
	Where results make sense

Topic: Hormesis

Related Topics

Ionizing radiation

US FIRST

Tung Chung

Brian Transeau

Doune

	Hormesis and Aging
		Hormesis is the term used to describe biological phenomena that are often adverse or detrimental but become beneficial when applied at low levels.
		The concept of biological hormesis is as important as that of homeostasis for the survival of the organism.
		Thus, hormesis in aging is the biological adaptive function to resist or blunt the age-related deleteriousness.
	www.innovitaresearch.org /news/06061501.html (1344 words)

	Hormesis - Wikipedia, the free encyclopedia
		In toxicology, hormesis is a dose response phenomenon characterized by a low dose stimulation, high dose inhibition, resulting in either a J-shaped or an inverted U-shaped dose response.
		Hormesis is the term for generally-favorable biological responses to low exposures to toxins and other stressors.
		Radiation hormesis is not generally accepted by The International Commission on Radiological Protection (ICRP), its U.S. counterpart, the National Council on Radiation Protection and Measurements (NCRP), the National Research Council Committees on the Biological Effects of Ionizing Radiation (the BEIR Committees), or the U.S. regulatory agencies.
	en.wikipedia.org /wiki/Hormesis (870 words)

	[No title]
		It appears the term "hormesis" itself arose in the 1940's after two scientists reported that the growth of fungi were stimulated at low concentrations by a certain substance.
		There is no doubt that accepting hormesis after several decades of adopting the LNT hypothesis would require a true "leap of faith" by these scientific groups and certainly by the regulatory agencies that review and typically adopt their recommendations.
		Hormesis, according to Dr. Sagan, is not presently accepted because it does not fit the widely held beliefs that 1) radiation exposure is harmful; 2) radiation exposure is harmful at all levels; and 3) there are no effects at low doses which cannot be predicted from effects noted at high-dose levels.
	www.iem-inc.com /prhorr.html (3319 words)

	Our Stolen Future: Irresponsible flaws in proposed regulatory application of hormesis
		Hormesis has been proposed to be an adaptive response to low-level exposures that has beneficial consequences.
		This interpretation has been used by two of the principal proponents of hormesis, Edward Calabrese and Linda Baldwin, to argue that exposure standards not only are too stringent and costly, but may also perversely cause harm because, if met, they would prevent the beneficial impacts of low-level exposure.
		In research on the impact of atrazine on frog development, and in studies of the low dose impacts of bisphenol A, funding by a source with a strong economic interest in the outcome strongly biased the research toward outcomes that were favorable.
	ourstolenfuture.org /NewScience/regulatory/2005/2005-0615thayeretal.htm (1193 words)

	IS SIMILIA PRINCIPLE RELATED TO THE ARNDT-SCHULTZ LAW AND HORMESIS, Monaco International Talks
		Hormesis is considered as a non-specific phenomenon increasing the resistance and growth of the treated organism.
		Starting from the idea of this "vital activity" and to demonstrate the poisoning resistance of living organisms, it was proposed to use sub-lethal dosis pretreatment of a poison followed by lethal dosis of the same poison (as it was used by Mithridate or by Raspoutine to prevent poisoning lethal agression).
		Whatever the interest of the Arndt-Schultz law and hormesis to demonstrate the adaptative capacity of a living organism or to develop the identity principle, they are not helpful for the interpretation of the similia principle which is the foundation of Homeopathy.
	www.entretiens-internationaux.mc /similia.htm (1869 words)

	The Scientist : Challenging Dose-Response Dogma (Site not responding. Last check: 2007-10-13)
		Having been relegated for years to the toxicological waste heap by misconception and inertia, hormesis is regaining respect, and I believe that such modeling will replace the outmoded standards in toxicology and may ultimately influence most areas of biological research.
		On the political side, the hormesis concept, immediately upon its discovery in the 1880s, became closely but incorrectly associated with the medical practice of homeopathy, becoming a victim of collateral damage in a long-standing and intensely bitter confrontation with traditional medicine.
		In an ironic twist, the increased recognition, acceptance, and use of hormesis within the biomedical research and clinical medicine domains may prove to be the equivalent of a toxicological Trojan Horse, which will lead to its eventual acceptance in environmental risk assessment.
	www.the-scientist.com /2005/2/14/22/1 (1568 words)

	International Hormesis Society - Home
		Hormesis is a dose-response phenomenon characterized by low-dose stimulation and high-dose inhibition.
		Hormesis, the biological and toxicological concept that small quantities have opposite effects from large quantities, is reviewed with emphasis on its relevance to nutrition.
		But hormesis is a possible, if not highly probable, iconoclastic notion, first postulated either in the 16th century or the 1880s, but gaining flattering attention within the last decade, that humans actually need small amounts of poison in their diets.
	www.hormesissociety.org /index.htm (968 words)

	Hormesis
		Hormesis is the general biological response to exposures to toxins and other stressors.
		In the absence of policies to accept hormesis, and with hundreds of billions at stake, as well as many people's livelihoods, the controversy is very active.
		Hormesis was associated with the medical practice of homeopathy in its early years and was stigmatized as a result.
	www.mrsci.com /Toxicology/Hormesis.php (613 words)

	WorldNetDaily: Toxins lead to healthier lives?
		Hormesis, the scientific theory that humans actually need small amounts of poison in their diets, could be the most important environmental event of the 21st century if proved valid.
		But hormesis is a possible, if not highly probable, iconoclastic notion, first postulated either in the 16th century or the 1880s but gaining flattering attention within the last decade.
		One who apparently did not know about hormesis, or at least whose office refused to respond to repeated messages about it, was recently resigned EPA administrator Christine Todd Whitman, who would not comment even on the work of her own people on this matter.
	www.worldnetdaily.com /news/article.asp?ARTICLE_ID=36421 (1608 words)

	Glutathione and Radiation Hormesis (Site not responding. Last check: 2007-10-13)
		We are investigating "hormesis", a beneficial effect of radiation observed in both animal experiments and human epidemiological data as an extended life span in subjects exposed to low radiation doses compared to matched unirradiated controls.
		This impedes incorporating hormesis into risk analysis, because risks must be assessed on the basis sound scientific principles in order to be defensible.
		Although this finding was disappointing, it implies that hormesis is likely to be a subtle process expressing its beneficial effects over a period of years.
	lowdose.tricity.wsu.edu /2001mtg/abstracts/bailey.htm (551 words)

	Environmental Health News: Archives
		A peer-reviewed commentary in the scientific journal of the National Institute of Environmental Health Sciences concludes that it is irresponsible for proponents of hormesis to portray chemicals with numerous adverse effects as having "benefits" from low-dose stimulation while ignoring their hazards.
		A scientist finds benefit in small doses of toxins For more than a decade, Calabrese, a respected professor of toxicology at the University of Massachusetts, endured ridicule as he gathered evidence showing that small amounts of poisons, even cancer-causing chemicals like dioxin, can be good for you.
		Hormesis: Sipping from a poisoned chalice People have believed since antiquity that tiny doses of toxicants can be healthful.
	www.environmentalhealthnews.org /archives.jsp?sm=&tn=1subject,text,publishername&tv=hormesis&ss=1 (935 words)

	Chemical Hormesis - Access to Energy - Pro-Science, Pro-Technology, Pro-Freedom (Site not responding. Last check: 2007-10-13)
		He concluded, however, that this effect was the result of oxidative destruction of biological macromolecules by Vitamin C and the resulting stimulation of the immune system by biochemical breakdown products - chemical hormesis by a substance with (at higher doses) a toxic effect.
		Pauling drank one or two drinks of hard liquor (usually gin) per day, did not smoke, and increased his Vitamin C intake from 3 grams per day at the age of 67 to 18 grams per day at the age of 92.
		By practicing chemical hormesis, however, (whether he recognized it or not) he increased his chances of living in good health for many years.
	www.accesstoenergy.com /view/ate/s41p900.htm (744 words)

	RADIATION HORMESIS *
		Hormesis was the word suggested by Southam and Erlich (1943) who determined the effective concentration of phenolic compounds in wood which protects trees from fungi decay.
		Shared characteristics are listed in part A. Characteristics of homeopathy which do not typify hormesis are listed in part B. And hormesis characteristics not found in homeopathy are listed in part C. The major difference is that hormesis is a general phenomenon while homeopathy involves one, or very few, specific compounds for each malady.
		Thus, radiation hormesis is comparable to those essential nutrients which are not present in adequate quantities in certain environments.
	www.webstore.fr /eim/TMP953135741.htm (2606 words)

	Aging
		Hormesis - beneficial effects of mild stress or challenge - is a way to improve upon the natural homeodynamic network of vitagenes which assure longevity.
		The idea of applying hormesis in aging research and therapy is based in the fact that one of the immediate cellular responses to external and internal stress is the upregulation of maintenance and repair pathways.
		Furthermore, it may be possible to use the approach of hormesis in order to identify genes which are important for aging and longevity.
	imsb.au.dk /~rattan/aging.html (2241 words)

	Hormesis: a revolution in toxicology, risk assessment and medicine
		To this end, we have developed a rigorous a priori process to assess and quantitatively evaluate possible hormetic dose−response relationships, estimate the frequency of hormetic dose responses in the toxicological literature and estimate which toxicological model occurred more frequently in the peer-reviewed literature (Calabrese, 2002, 2003; Calabrese and Baldwin, 2001a, 2003b).
		In short, the hormesis model clearly outperforms either of the other two competitive models in fair head-to-head competition (Calabrese and Baldwin, 2001b, 2003a).
		In fact, as the hormesis hypothesis can actually be tested with the available data, for the first time in the modern history of cancer risk assessment, we would be able to rely on a verifiable dose−response model and not depend on unverifiable extrapolations of animal data to estimate actual risk to humans.
	www.nature.com /cgi-taf/DynaPage.taf?file=/embor/journal/v5/n1s/full/7400222.html (3050 words)

	ES&T Online News: Hormesis gets massive data support
		Hormesis [160KB PDF]explains that low doses can have the opposite effect of high doses, such that chemicals that can have harmful biological effects in relatively large amounts can have beneficial effects in small quantities.
		This means that hormesis has the potential to overturn some environmental regulations, and its relevance to such policies has engendered lively debate.
		“If hormesis were used in the decision-making process to allow higher exposures to toxic and carcinogenic agents, this would substantially increase health risks for many, if not most, segments of the general population,” they wrote.
	pubs.acs.org /subscribe/journals/esthag-w/2006/oct/science/rr_hormesis.html (795 words)

	An Introduction to Radiation Hormesis (Site not responding. Last check: 2007-10-13)
		They published their findings regarding the new term "hormesis" in 1943 (Bruce M. Generally, hormesis is any stimulatory or beneficial effect, induced by low doses of an agent, that can not be predicted by the extrapolation of detrimental or lethal effects induced by high doses of the same agent.
		The concept of radiation hormesis is usually applied to physiological benefits from low LET radiation in the range of 1-50 cGy total absorbed dose (Macklis 1991).
		It is concluded that according to new findings, the existence of radiation hormesis and adaptive response are not deniable and abandoning the LNT theory in low dose risk estimations will be a real nessecity in the near future.
	www.angelfire.com /mo/radioadaptive/inthorm.html (2662 words)

	Looking Fit 10/2000: Small amounts of something bad may be good for you
		Therefore, the hormesis conundrum states that while too much of a good thing may be bad for you, a small amount of something bad may be good for you.
		The worldwide healthcare community is beginning to take another look at hormesis due to its importance, particularly in the case of substances such as vitamins and minerals that are essential for life at low doses but toxic at higher ones.
		That is why it is important to take the time to explain to your clients the concept of hormesis and that it substantiates the premise that the benefits of sensible, moderate and responsible exposure to UVR outweigh the minimal and manageable risks involved.
	www.lookingfit.com /articles/0a1column1.html (1096 words)

	Science & Technology at Scientific American.com: Nietzsche's Toxicology -- [ HORMESIS ] -- Whatever doesn't kill ... (Site not responding. Last check: 2007-10-13)
		Called hormesis, this phenomenon appears to be primarily an adaptive response to stress, says toxicologist Edward J. Calabrese of the University of Massachusetts at Amherst.
		Thus, it might be possible to refine pollution standards so that we can reap the benefits of hormesis while still being protected against adverse effects in the environment.
		In some sense, endocrine disruption appears to be the opposite of hormesis, in which low doses could have unsuspected harmful effects because of the contaminant's chemical similarity to hormones.
	www.sciam.com /article.cfm?articleID=00019A70-0C1C-1F41-B0B980A841890000&ref=sciam (804 words)

	Is Radiation Good For You? - - science news articles online technology magazine articles Is Radiation Good For You? (Site not responding. Last check: 2007-10-13)
		Hormesis and homeopathy share similar trappings, but they are very different concepts.
		Hormesis has been a "marginalized hypothesis" for decades, he said, yet the data suggest that it's a fundamental, unifying aspect of biology.
		Hormesis might be a cruel joke—biology's equivalent of cold fusion—but he sees important differences.
	www.discover.com /issues/dec-02/features/featradiation (4136 words)

	Radiation Hormesis
		Hormesis: The notion that small doses of a toxin can be helpful.
		In surveying the literature, T. Luckey found that hormesis was common, particularly when the "dose" was of ionizing radiation.
		In August 1985, a Conference on Radiation Hormesis in Oakland, California, recognized the reversal in concepts of radiation effects.
	www.alamut.com /proj/98/nuclearGarden/bookTexts/Rad_hormesis.html (1442 words)

	Energy Citations Database (ECD) - Energy and Energy-Related Bibliographic Citations (Site not responding. Last check: 2007-10-13)
		Hormesis is the stimulation of any system by low doses of any agent.
		Radiation hormesis encompasses the beneficial effects of low-dose irradiation in both animals and humans.
		The radiation hormesis model comprises statistically significant (X{sup 2} test) results that compare total death rates and cancer death rates in exposed and unexposed nuclear workers.
	www.osti.gov /energycitations/product.biblio.jsp?osti_id=415810 (233 words)

	NOT IMMUNE TO BRAINWASH - Access to Energy Newsletter Archive
		are beneficial; the phenomenon is known to physicians as hormesis.
		In the case of radiation, hormesis was known to few people until the publication of Prof.
		Today it is recognized among experts in the field, though not by the media machine, that low level radiation is not only beneficial to living organisms (which have never been without it), but essential to their life.
	www.accesstoenergy.com /view/atearchive/s76a5220.htm (439 words)

	RE: Radiation Hormesis (Site not responding. Last check: 2007-10-13)
		To show the effects of hormesis, no effect, and ill effect the students all received seeds from each exposed group plus seeds that did not get any extra dose (controls).
		I am perfectly ready to accept hormesis, but in the current radiophobic climate, I believe we are better off just claiming no harm at less than a particular dose.
		Hormesis is one of those phenomena that even if it is real, doesn't SOUND real.
	www.vanderbilt.edu /radsafe/0401/msg00422.html (509 words)

	Hormesis Theory: Tiny Bits of Toxins Do Affect People: Tiny doses of toxins and radiation in the environment, once ... (Site not responding. Last check: 2007-10-13)
		The hormesis theory is that small doses of a toxin can make a human cell grow stronger.
		The once-discredited theory, hormesis, is making its way into mainstream science and will be a central topic at next month's Society of Toxicology conference in Baltimore.
		The idea behind hormesis is that parts of human cells change when challenged with small doses of toxins.
	www.mindfully.org /Pesticide/2004/Hormesis-Theory-Toxins27feb04.htm (595 words)

	jousciexplorationltr
		Numerous animal studies indicate a radiation-induced hormesis occurs in major physiologic functions (Luckey, 1980; Luckey, 1991) and at all levels ranging from biochemical to organismal (Macklis and Beresford, 1991).
		Radiation hormesis researcher, Myron Pollycove, M.D. cites several examples, including reductions in lung cancer incidence with increasing radon exposure, and reductions in breast cancer rates in Canadian women exposed to low doses of radiation from lung fluoroscopy.
		Additionally, Pollycove concludes that a tenfold increase of annual background radiation stimulates overall biosystem activity by approximately 20%, producing a significant decrease in the metabolic rate of mutations and corresponding decreases of cancer mortality and mortality from all causes (Pollycove, 1998).
	www.homestead.com /newvistas/jousciexplorationltr.html (1910 words)

Try your search on: Qwika (all wikis)