Human serum albumin

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Topic: Human serum albumin

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	Pfam 16.0 : Serum_albumin
		The principal regions of ligand binding to human serum albumin are located in hydrophobic cavities in subdomains IIA and IIIA, which exhibit similar chemistry.
		The 3D structure of human serum albumin has been determined by X-ray crystallography to a resolution of 2.8A MEDLINE:1630489.
		Atomic structure and chemistry of human serum albumin.
	pfam.wustl.edu /cgi-bin/getdesc?acc=PF00273

	Detergents as Probes of Hydrophobic Binding Cavities in Serum Albumin and Other Water-Soluble Proteins -- Kragh-Hansen et al. 80 (6): 2898 -- Biophysical Journal
		The spectra were recorded at 20°C by excitation of 7.5 µM of defatted human serum albumin at 290 nm in the same way as described in Fig.
		The spectra were recorded at 20°C by excitation of 7.5 µM defatted human serum albumin at 290 nm in the same medium as described in Fig.
		no evidence for micellar or cooperative interaction of serum albumin
	www.biophysj.org /cgi/content/full/80/6/2898

	Molecular Interactions Between Inhaled Anesthetics and Proteins -- Eckenhoff and Johansson 49 (4): 343 -- Pharmacological Reviews
		Inhaled Anesthetic Binding Sites in Human Serum Albumin
		The Role of Electrostatic Interactions in Human Serum Albumin Binding and Stabilization by Halothane
		Anesthetic-like Interactions of Nitric Oxide with Albumin and Hemeproteins.
	pharmrev.aspetjournals.org /cgi/content/abstract/49/4/343

	Serum Albumin in Mammalian Cornea: Implications for Clinical Application -- Nees et al. 44 (8): 3339 -- Investigative Ophthalmology & Visual Science
		study found that both human and bovine serum albumin in the
		serum albumin in the mouse and bovine cornea.
		Serum albumin may also be an antioxidant reacting
	www.iovs.org /cgi/content/full/44/8/3339

	Human Serum Albumin Crystals and Method of Preparation
		A detailed knowledge of the three-dimensional structure of serum albumin, especially the human form, is imperative in order to fully understand the binding nodes and physical properties of this multifaceted protein.
		An understanding of the crystal structure of serum albumin is critical in the development of new human pharmaceuticals.
		The human serum albumin crystal growth process is part of NASA's Technology Transfer Program and is available for licensing.
	www.nasasolutions.com /Patents/(36).html

	Do You Know Your Serum Albumin?
		Your physician will be sent a copy of the human clinical serum albumin trials (test papers).
		No single test is more predictive of morbidity, mortality, and surgical success than serum albumin.
		In study after study of many populations, comprised of both healthy people and patients with acute or chronic illness, it was found that the estimated increase in the odds of death ranges from 24% to 56% for each 2.5g/L decrement in serum albumin concentration.
	www.anitafinley.com /sept00/serum.html

	bovine serum albumin based
		Phone: Serum-free defined liquid media Human Serum lbumin based bovine serum albumin based Bovine Serum Albumin based Storage Conditions -20�C during 18 months +4�C during 6 months (adding bovine serum albumin based Glutamate after 1 month).
		Connection types: bovine serum albumin based All types of standard connection components are available, bovine serum albumin based auto sealing ports, luer ports, multiple port connectors, bovine serum albumin based sample bags, filters, etc. Flexible tube connections are available bovine serum albumin based including peristaltic pump flexible tubing.
		The aliquots can bovine serum albumin based then be stored at -20�C for 18 months or +4�C for 6 months Laboratories bovine serum albumin based are focused to the creation, development and production of bovine serum albumin based innovative solutions in the domains of cell culture and tissue engineering.
	www.mabio.net /mabio_laboratories/bovine_serum_albumin_based.htm

	A nucleotide insertion and frameshift cause albumin Kenitra, an extended and O-glycosylated mutant of human serum albumin with two additional disulfide bridges -- Minchiotti et al. 268 (2): 344 -- European Journal of Biochemistry
		Thr): a glycoprotein variant of human serum albumin whose precursor has an aberrant signal peptidase cleavage site.
		Keywords: human serum albumin; extended genetic variant; O-glycosylation; disulfide bridges; frameshift.
		Albumin Kénitra is a new type of genetic variant of human
	www.ejbiochem.org /cgi/content/full/268/2/344

	Binding and Relaxometric Properties of Heme Complexes with Cyanogen Bromide Fragments of Human Serum Albumin -- Monzani et al. 83 (4): 2248 -- Biophysical Journal
		Binding and Relaxometric Properties of Heme Complexes with Cyanogen Bromide Fragments of Human Serum Albumin -- Monzani et al.
		is currently thought that human serum albumin (HSA) and hemopexin
		C (124-298), A (299-585), and D (1-298) of human serum albumin
	www.biophysj.org /cgi/content/full/83/4/2248

	What is human serum albumin?
		Human serum albumin (HSA) is a high molecular weight endogenous plasma protein (MW 67 kDa).
		The variety of albumin function for all transport stages is based on high conformation flexibility of this protein molecule and on the lability of its binding site characteristics.
		Transport properties of HSA depend on its ability for competitive metabolite adsorption at the loading stage, on binding site�s capacities, strength of ligand fixation during their transfer in blood, and on the rate of albumin-ligand complex dissociation under interaction with target objects.
	www.medinnovation.de /background/hsa.htm

	Electrospray ionization mass analysis of normal and genetic variants of human serum albumin -- Brennan 44 (11): 2264 -- Clinical Chemistry
		Electrospray ionization mass analysis of normal and genetic variants of human serum albumin
		Electrospray ionization mass analysis of normal and genetic variants of human serum albumin -- Brennan 44 (11): 2264 -- Clinical Chemistry
		Both normal albumin (Al A) and genetically modified forms were
	www.clinchem.org /cgi/content/abstract/44/11/2264

	Use of the KlADH4 Promoter for Ethanol-Dependent Production of Recombinant Human Serum Albumin in Kluyveromyces lactis -- Saliola et al. 65 (1): 53 -- Applied and Environmental Microbiology
		The secretion of human serum albumin from the yeast Saccharomyces cerevisiae using five different leader sequences.
		Physiological approach to heterologous human serum albumin production by Kluyveromyces lactis in chemostat culture.
		Regulation of the chelatin promoter during the expression of human serum albumin or yeast phosphoglycerate kinase in yeast.
	aem.asm.org /cgi/content/full/65/1/53

	Human Serum Albumin antibody [BSA-7G10] (ab3781) datasheet
		If Human Serum Albumin antibody [BSA-7G10] (ab3781) does not perform as described on this datasheet, a replacement or refund will be offered.
		At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this Human Serum Albumin antibody [BSA-7G10] is on this datasheet.
		Compatible Secondaries for Human Serum Albumin antibody [BSA-7G10]
	www.abcam.com /?datasheet=3781

	Interactions of very long-chain saturated fatty acids with serum albumin -- Choi et al. 43 (7): 1000 -- Journal of Lipid Research
		Abbreviations: HSA, human serum albumin; Ms, methanesulfonyl; PC, phosphatidylcholine; SUV, small unilamellar vesicles; VLCFA, very long-chain fatty acids
		Interactions of very long-chain saturated fatty acids with serum albumin -- Choi et al.
		The remarkable binding properties of serum albumin have been
	www.jlr.org /cgi/content/abstract/43/7/1000

	Binding of the General Anesthetics Propofol and Halothane to Human Serum Albumin. HIGH RESOLUTION CRYSTAL STRUCTURES -- Bhattacharya et al. 275 (49): 38731 -- Journal of Biological Chemistry
		Human serum albumin (HSA) is one of the most abundant proteins in the circulatory system and plays a key role in the transport
		Binding of the General Anesthetics Propofol and Halothane to Human Serum Albumin.
		The abbreviation used is: HSA, human serum albumin.
	www.jbc.org /cgi/content/full/275/49/38731

	Human Serum Albumin (HSA) and other species albumin antibodies from Research Diagnostics Inc
		Human Serum Albumin (HSA) and other species albumin antibodies from Research Diagnostics Inc
		Application: Suitable for ELISA techniques or radiolabelling, purification of human serum albumin.
		Does not react with bovine serum albumin and egg white albumin.
	www.researchd.com /miscabs/trk4t24.htm

	Human Serum Albumin and its N-Terminal Tetrapeptide (DAHK) Block Oxidant-Induced Neuronal Death -- Gum et al. 35 (2): 590 -- Stroke
		Human Serum Albumin and its N-Terminal Tetrapeptide (DAHK) Block Oxidant-Induced Neuronal Death -- Gum et al.
		Human Serum Albumin and its N-Terminal Tetrapeptide (DAHK) Block Oxidant-Induced Neuronal Death
		stroke have shown that human serum albumin (HSA) significantly
	www.strokeaha.org /cgi/content/abstract/35/2/590

	Fatty acids carried on albumin modulate proximal tubular cell fibronectin production: a role for protein kinase C -- Arici et al. 17 (10): 1751 -- Nephrology Dialysis Transplantation
		human serum albumin (rHSA) or palmitate (P)-, stearate (S)-,
		Fatty acids carried on albumin modulate proximal tubular cell fibronectin production: a role for protein kinase C -- Arici et al.
		Albumin Signals the Coming of Age of Proteinuric Nephropathy
	ndt.oupjournals.org /cgi/content/abstract/17/10/1751

	Ann Intern Med -- Sign In Page
		Patient Survival after Human Albumin Administration: A Meta-Analysis of Randomized,...
		Please note: PDFs are free 6 months after publication.
		To view this item, select one of the options below:
	www.annals.org /cgi/content/full/135/3/149

	Structural basis of albumin-thyroxine interactions and familial dysalbuminemic hyperthyroxinemia -- Petitpas et al. 100 (11): 6440 -- Proceedings of the National Academy of Sciences
		Human serum albumin (HSA) is the major protein component of
		the elevated serum thyroxine levels associated with familial
		Edited by John Kuriyan, University of California, Berkeley, CA, and approved April 2, 2003 (received for review November 26, 2002)
	www.pnas.org /cgi/content/abstract/100/11/6440

	Mumpsvax Online, Description, Chemistry, Ingredients - Mumps Virus Vaccine Live - RxList Monographs
		The cells, virus pools, fetal bovine serum, and human albumin are all screened for the absence of adventitious agents.
		The growth medium for mumps is Medium 199 (a buffered salt solution containing vitamins and amino acids and supplemented with fetal bovine serum) containing SPGA (sucrose, phosphate, glutamate, and human albumin) as stabilizer and neomycin.
		Each dose of the vaccine is calculated to contain sorbitol (14.5 mg), sodium phosphate, sucrose (1.9 mg), sodium chloride, hydrolyzed gelatin (14.5 mg), human albumin (0.3 mg), fetal bovine serum (
	www.rxlist.com /cgi/generic3/mumpsvax.htm (213 words)

	Human Genome Sciences: Albuferon
		One subject developed antibodies to human serum albumin.
		Design of yeast-secreted albumin derivatives for human therapy: biological and antiviral properties of a serum albumin-CD4 genetic conjugate.
		Human Genome Sciences is developing Albuferon as a potential treatment for chronic hepatitis C. Clinical and preclinical results to date suggest that Albuferon is well tolerated, remains in the blood substantially longer than is reported for recombinant interferon alpha and pegylated interferon alpha, and exhibits robust antiviral activity.
	www.albugranin.com /products/albuferon.html (213 words)

	ABI Online: Products: Cell Biology Products
		Following induction with PHA, the leukocytes are incubated for 40 to 72 hours in Dulbecco's Modified Eagle Medium (DMEM) supplemented with 5 mg/ml human serum albumin and 10 ug/ml Gentamicin and the crude TCGF fluids harvested.
		Incubate activated cells 5 days at 37°C in 5% CO Wash cells 3 times in RPMI-1640 fetal bovine serum 10%.
		The product is lectin-free and capable of stimulating long-term growth of adult human T-lymphocytes when assayed by long-term proliferation assays in vitro.
	www.abionline.com /products/cellbio/specs/03020.htm (320 words)

	Glucose and free radicals impair the antioxidant properties of serum albumin -- BOURDON et al. 13 (2): 233 -- The FASEB Journal
		Fluorescence behavior of tryptophan residues of bovine and human serum albumins in ionic surfactant solutionsa comparative study of the two and one tryptophan(s) of bovine and human albumins.
		Antioxidant potential of anaerobic human plasmarole of serum albumin and thiols as scavengers of carbon radicals.
		High serum alpha-tocopherol, albumin, selenium and cholesterol, and mortality from coronary heart disease in northern Finland.
	www.fasebj.org /cgi/content/full/13/2/233 (320 words)

	Albumin
		Evaluation of human serum albumin cobalt binding assay for the assessment of myocardial ischemia and myocardial infarction.[comment].
		Recombinant human serum albumin + oleate, 2.4Å, #1GNI, Petipas, I., 2001a.
		Case #36 is a 29-year old Canadian First Nations woman in Saskatchewan with serum albumin concentration of 0.2 g/L. She displayed a striking lipodystrophy with massive cellulite deposits on her thighs and buttocks.
	www.albumin.org (320 words)

	Kinetics of Bilirubin Transfer between Serum Albumin and Membrane Vesicles -- Zucker et al. 270 (3): 1074 -- Journal of Biological Chemistry
		Thermodynamic analysis suggests that the binding site on bovine serum albumin demonstrates higher specificity for the bilirubin molecule than that on human or rat serum albumin, which exhibit similar binding characteristics.
		(±S.D.) at 25 °C for human, rat, and bovine serum albumins, respectively.
		To better characterize the mechanism of bilirubin delivery to the hepatocyte, stopped-flow techniques were utilized to study the kinetics of bilirubin transfer between serum albumin and both model phospholipid and native hepatocyte plasma membrane vesicles.
	www.jbc.org /cgi/content/abstract/270/3/1074 (568 words)

	Welcome to Mediatech, Inc. - Sera
		35-095-LR, Human Serum Albumin, 25% USP Therapeutic Grade, sold as a 10 pack of 50mL bottle
		35-060-CI, Human AB Serum, sold as a single 100mL bottle
		35-015-CV, Fetal Bovine Serum, Premium, sold as a single 500mL bottle
	www.cellgro.com /shop/customer/home.php?cat=343&js=n (115 words)

	Albumin for nephrotic syndrome
		Albumin (Normal serum albumin (human), Salt-poor albumin, SPA, Albuminar, Albumisol, Plasbumin)
		Albumin is primarily used for short-term treatment of nephrotic syndrome.
		Albumin is a protein that is made in the liver and released into the blood.
	www.webmd.com /hw/kidney_failure/tv7231.asp (278 words)

	Millipore - Technical Library - Montage Albumin Deplete Kit
		The kit’s centrifugal columns are prepacked with an affinity resin that removes >65% of albumin from typical human serum samples.
		Radial immunodetection assay revealed an average of 66% albumin reduction across the 10 separate depletions with a standard deviation of 3.2 and a CV of 2.1%.
		To accurately assess albumin removal, all sample loads were volume normalized to the undepleted starting sample.
	www.millipore.com /publications.nsf/docs/PF1770en00 (523 words)

	Albumin
		From both studies they concluded that the overall conformation of albumin in neutral solution is rigid and very similar to the 80x80x80x30 heart-shaped structure derived from crystallography of human albumin.
		"Dielectric behavior and atomic structure of serum albumin." Biophys.Chem.
		The albumin is said to act as a sink for NO(+) and as a modulator for its transfer from the vessel wall to red cell hemoglobin.
	www.albumin.org (4884 words)

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In the News (Wed 30 Dec 09)