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Topic: Huperzine A


In the News (Sat 28 Nov 09)

  
  Huperzine A - Supplements
Huperzine A, is a purified alkaloid extract from a Chinese moss, Huperzia serrata (as such, it is really more of a “naturally derived drug” than a true herbal remedy) The moss has been used in Traditional Chinese Medicine for treating fever, inflammation, schizophrenia and memory loss.
In animal studies, daily oral administration of huperzine A has been shown to produce a significant improvement in learning ability (maze tasks) that is strongly correlated to promotion of blood flow and inhibition of acetylcholinesterase activity in various regions of the brain (cortex and hippocampus).
Huperzine occurs in 2 forms, “A” and “B” as well as 2 enantiomers (-) and (+).
www.supplementwatch.com /suplib/supplement.asp?DocId=1291   (1079 words)

  
  Huperzine A article
Huperzine A (HupA for short), an alkaloid found in the Chinese herb Huperzia serrata, is effective in improving cognitive and memory abilities in humans, including those with Alzheimer's disease.
Huperzine A is superior to the drugs tacrine and donepezil, which are acetylcholinesterase inhibitors widely prescribed for Alzheimer's disease.
Efficacy of tablet huperzine-A on memory and cognition in patients with benign senescent forgetfulness.
www.smartnutrition.info /info-huperzine.htm   (1084 words)

  
 Alzforum: Drugs In Clinical Trials - Huperzine A
Huperzine A increases sAPPa, by increasing levels of protein kinase C isoform a in ICV infused rats and cell culture (Zhang et al., 2004).
Huperzine A may counteract the effects of such drugs as dicyclomine or propantheline that are used to decrease acetylcholine’s effects in the treatment of diarrhea-prominent irritable bowel syndrome.
Huperzine A is currently in phase 4 in China for treatment of Alzheimer disease, and in the U.S., a multicenter (29 centers in 17 states), double-blind, placebo controlled phase 2 clinical trial is in enrollment stage until late spring 2007, with completion of the trial expected in late 2008, clinical trial NCT00083590.
www.alzforum.org /dis/tre/drc/detail.asp?id=53   (959 words)

  
 Geriatric Studies Center- Alzheimer's Disease, Memory Impairment, Clinical Trials, Research, Dementia, Mild Cognitive ...
Huperzine A is a natural cholinesterase inhibitor derived from the Chinese herb Huperzia serrata.
There is evidence that huperzine A may compare favorably in symptomatic efficacy to cholinesterase inhibitors currently in use.
In addition, huperzine A has antioxidant and neuroprotective properties that suggest that it may be useful as a disease-modifying treatment for Alzheimer’s disease (AD).
www.usc.edu /schools/medicine/departments/psychiatry_behavioralsciences/research/gsc/research/study_huperzine.php   (520 words)

  
 Huperzine A Huperzine
Huperzine A is an alkaloid found in the Chinese herb Huperzia Serrata.
Huperzine A is not known to be toxic even when administered at 50 to 100 times the human therapeutic dose.
Cheng DH, Ren H, Tang XC (1996) Huperzine A, a novel promising acetylcholinesterase inhibitor, Neuroreport 8: 97-101.
www.netshopsusa.com /shop/huperzine.a.html   (763 words)

  
 Huperzine A Memory Extract
Called Huperzine A, this memory extract appears to have the power to sharpen the mind and potentially ward off the devastating effects of Alzheimer's Disease, particularly in the early stages.
Mental improvements associated with huperzine A extract appear to stem from the compound's ability to inhibit the breakdown of acetylcholine, a brain chemical essential to memory.
Vincent A. Unravelling [sic] the pathogenesis of myasthenia gravis.
www.superbherbs.com /HuperzineA.html   (1273 words)

  
 Huperzine   (Site not responding. Last check: )
Huperzine A appears to work on areas of memory and can possibly benefit those with loss of short term memory; as well as in conditions of long term memory loss, such as Alzheimer's disease.
Huperzine A is derived from two different types of Chinese club moss, Huperzia serrata and Lycopodium selago.
Huperzine A directly affects the concentration of a particular neurotransmitter in the brain known as acetylcholine.
www.supplementnews.org /huperzine   (908 words)

  
 Huperzine : by Ray Sahelian, MD
Huperzine A. Drugs R D. Huperzine A, an alkaloid isolated from Huperzia serrata, is a putative nootropic agent developed by the Chinese Academy of Sciences.
Huperzine A is currently in phase III trials in China for the treatment of patients with Alzheimer's disease.
injection, huperzine A (0.25-0.75 micromol/kg), donepezil (2-6 micromol/kg) and rivastigmine (0.75-1.5 micromol/kg) dose-dependently elevated the concentration of acetylcholine.
www.raysahelian.com /huperzinea.html   (1382 words)

  
 Huperzine A for Memory and Learning
Huperzine A possesses a longer duration of action and higher therapeutic index, and the peripheral cholinergic side effects are minimal at therapeutic doses.
Huperzine A are considered a promising therapeutic agent for Alzheimer's disease and memory deficit.
Huperzine A showed significant improvements in their memory, cognitive and behavioral functions versus only 36% of those receiving the placebo.
www.bodyandfitness.com /Information/Health/Research/huperzineA.htm   (1105 words)

  
 ThirdAge: Huperzine A
Huperzine A is a highly potent compound with a recommended dose of only 100 to 200 micrograms twice a day for age-related memory loss.
Pharmacokinetics of huperzine A in rats and mice [in Chinese].
Huperzine A, a potential therapeutic agent for dementia, reduces neuronal cell death caused by glutamate.
www.thirdage.com /healthgate/files/21761.html   (1226 words)

  
 Huperzine Clinical Studies
In a 2003 double-blind, randomized study, Huperzine A, in injectable form, was tested against a saline control in 56 patients with multi-infarct dementia or senile dementia and in 104 patients with senile and pre-senile simple memory disorders.
Huperzine A produced significant positive effects as measured by the Wechsler Memory Scale.
Effects of a memory enhancing peptide on cognitive abilities of brain-lesioned mice: additivity with huperzine A and relative potency to tacrine - Effects of a memory enhancing peptide on cognitive abilities of brain-lesio...
www.huperzine.net /herbal-remedies/huperzine/huperzine-clinical-studies   (617 words)

  
 Biochem-online database-HuperzineA
Huperzine A is a reversible AChE inhibitor that prevents the degradation of endogenous acetylcholine and was used to releave the memory loss and other cognitive defects of Alzheimer's patients.
Huperzine A is the active constituent with memory-enhancing properties found in the club moss, Huperzia serrata (Thunb.).
Huperzine A appears to be a very well crafted invention of Mother Nature that is capable of filling the active site of the enyzme acetylcholinesterase, the enzyme that degrades the neurotransmitter acetylcholine.
home.ust.hk /~neltklee/huperzine1.htm   (251 words)

  
 Huperzine Benefits
Huperzine A may be used to treat dementia, memory loss, and other cognitive deficiencies.
Huperzine A is a potent inhibitor of acetylcholine esterase, superior in activity to TACRINE, the first drug licensed in the USA for Alzheimer’s disease and E2020 which was licensed recently by Eisai Pharmaceuticals.
Huperzine A has been proven superior to drugs licensed for the treatment of Alzheimer’s, including the leading anticholinesterase drugs physostigmine and tacrine.
www.huperzine.net /herbal-remedies/huperzine/huperzine-benefits   (576 words)

  
 Huperzine - FAQ
Huperzine A is a plant alkaloid derived from the Chinese club moss plant, Huperzia serrata, which is a member of the Lycopodium species.
Huperzine A may counteract the effects of drugs -- such as dicyclomine, Levsin, and propantheline -- that are used to decrease acetylcholine's effects.
Huperzine A should only be used with a physician's recommendation and monitoring.
www.huperzine.net /herbal-remedies/huperzine/huperzine---faq   (329 words)

  
 Huperzine A Dosage and Side Effects
Huperzine A is a plant extract derived from Chinese Club Moss.
In a double-blind trial with a group of 56 patients suffering from senile dementia as well as a group of 104 patients with senile and pre-senile memory loss, Huperzine A was demonstrated to be effective for improving memory.
Huperzine A is not known to be toxic even when administered at 50 to 100 times the human therapeutic dose.
www.femhealth.com /HuperzineA.html   (728 words)

  
 Researchers test whether huperzine A can effectively treat the symptoms of Alzheimer's disease
Huperzine A is used in China to treat Alzheimer's disease, and researchers at Rush are conducting a Phase II study to find out whether huperzine A can slow down or prevent Alzheimer's symptoms in patients with mild to moderate disease.
Huperzine A blocks the enzyme that breaks down Acetylcholine in the brain, and it is this loss of that chemical that leads to memory loss in Alzheimer's patients.
During the last two months, all participants will receive a dose of huperzine A. Phase III studies in China have shown that the effectiveness of huperzine A may be comparable to that of approved drugs for Alzheimer's while reducing the harsh side effects, such as gastrointestinal upset, that are common with traditional Alzheimer's medicines.
www.news-medical.net /?id=5437   (516 words)

  
 Huperzine.net - Improve your memory naturally!
Huperzine-A is a plant alkaloid derived from the Chinese club moss plant, Huperzia serrata, which is a member of the Lycopodium species.
During the past few years, Huperzine A, one of the chemicals in Chinese club moss, has been studied extensively for its potential in treating dementias such as Alzheimer's disease.
Additionally, in a small study of teenagers, Huperzine A appeared to enhance general mental functioning when it was taken consistently for as little as one month.
www.huperzine.net   (431 words)

  
 Huperzine Cautions
Huperzine A is not known to be toxic even when administered at 50 to 100 times the human therapeutic dose.
Huperzine A should be avoided by children, pregnant women and nursing mothers.
Huperzine A may cause the heart to beat slower than it would normally.
www.huperzine.net /herbal-remedies/huperzine/huperzine-cautions   (345 words)

  
 Carilion - HUPERZINE A - [Alternative Medicine]
Huperzine A is an extract from a moss called Huperaine serrata.
The amount depends on the strength of the medicine and the reason you are taking Huperzine A. If you are using this medicine without instructions from your caregiver, follow the directions on the medicine bottle.
Ved HS, Koenig ML, Dave JR et al: Huperzine A, a potential therapeutic agent for dementia, reduces neuronal cell death caused by glutamate.
www.carilion.com /kbase/htm/mdx-/ame0/287/mdx-ame0287.htm   (482 words)

  
 Huperzine A - Great Low Pricing! - Huperzine A   (Site not responding. Last check: )
ProHealth provides Huperzine A which is a powerful compound harvested from the club moss Huperzia serrata, is a popular mind supporting supplement that promotes enhanced brain function.
Huperzine A supports the nervous system's role in transmitting information from cell to cell, and promotes stronger nervous connections for healthy cognitive function and memory.
Huperzine A helps keep acetylcholine levels balanced so it does not break down as quickly, helping to improve the strength and duration of the nervous impulse.
www.immunesupport.com /huperzine_a.htm   (130 words)

  
 Ultra HealthNotes : ultralife
Huperzine A is an alkaloid found in huperzia that has been reported to prevent the breakdown of acetylcholine, an important substance needed by the nervous system to transmit information from cell to cell.
Another double-blind trial found that huperzine A (100–150 mcg two to three times per day for four to six weeks) was more effective for improving minor memory loss associated with age-related cognitive decline than the drug piracetam.
A double-blind study of huperzine A and piracetam in patients with age-associated memory impairment and dementia.
www.ultralifeshop.co.uk /healthnotes.asp?org=ultralife&ContentID=2113005   (790 words)

  
 Huperzine: The Proven Therapeutic Treatment for Memory Loss
Huperzine has also been shown to dramatically decrease the abnormally elevated free radical activity in both the brain of old animals10, and the blood of Alzheimer's victims11.
While Huperzine-A in a highly purified form has been used in the vast majority of research, Huperzine-A occurs naturally in extremely small quantities in the moss it is extracted from.
In addition to Huperzine-A, Vitamins C and E, ginkgo biloba, phosphatidylserine, vinpocetine, acetyl-l-carnitine, lipoic acid, bacopa, pregnenolone, and glycerylphosphorylcholine (GPC) are among the growing list of safe and effective therapeutic agents shown to improve memory and protect the brain from the devastating effects of free radical damage and diseases such as Alzheimer's.
www.smart-publications.com /articles/051005huperzine.php   (1791 words)

  
 Huperzine A - Drugs & Vitamins - Drug Library - DrugDigest
Huperzine A is one of the alkaloids contained in a plant known as Chinese club moss.
Huperzine A and huperzine B are two of the chemicals that have been separated from Chinese club moss.
Huperzine B is also an acetylcholinesterase inhibitor, but because its effects are much weaker than those of huperzine A, most research has focused on huperzine A. Synthetic forms of huperzine A have been made in chemical laboratories and they appear to be as effective as natural huperzine A in studies.
www.drugdigest.org /DD/PrintablePages/herbMonograph/0,11475,552633,00.html   (2313 words)

  
 Huperzine-A Natural Club Moss Extract Shows Promise for Enhancing Memory and Alertness Article
In one study, Huperzine A was found to be twice as effective in protecting mice against the lethal effects of the nerve agent soman when compared to physostigmine.6 Huperzine A’s effects lasted for six hours compared to only 90 minutes for physostigmine, providing further evidence for the slow clearance of Huperzine from the body.
Huperzine A is rapidly absorbed when taken orally, and possesses a very slow rate of dissociation from the enzyme and a longer duration of action.
Huperzine A has been shown to be effective in inhibiting the actions of AChE to increase acetylcholine concentrations and alleviate some of the symptoms associated with acetylcholine deficiencies.
www.vrp.com /art/300.asp   (1947 words)

  
 Liv4Evr.com - Huperzine-A for Better Health and Longer Life
Huperzine-A is a new supplement derived from an ancient traditional Chinese herbal medicine that offers hope to those suffering from Alzheimer’s disease and other age-related mental conditions.
In addition to benefiting Alzheimer’s, Huperzine’s memory-enhancing properties suggest that it may be an effective agent for improving memory and learning in healthy people as well.
It is estimated that in the past few years, more than 100,000 people have been treated in China with Huperzine-A. Researchers in China claim that it helps normal elderly individuals with memory problems as well as people with AD with no significant adverse side effects.
www.liv4evr.com /ten_pillars/huperzinea.php   (159 words)

  
 Huperzia serrata extract (containing Huperzine A)
Huperzine A is a potent inhibitor of acetylcholine esterase, superior in activity to TACRINE, the first drug licensed in the USA for Alzheimer’s disease and E2020 which was licensed recently by Eisai Pharmaceuticals.
In addition, Huperzine A has been shown to protect neuronal cells in culture from death caused by the excitoamino acid glutamate.
Huperzine A is highly specific for brain acetylcholine esterase (AChE) vs. AChE found elsewhere in the body.
www.brainlightning.com /huperzine.html   (1275 words)

  
 Huperzine A
Huperzine A is an alkaloid isolated from the Chinese Club Moss Huperzia serrata.
Huperzine A is a potent acetylcholine esterase inhibitor.
Huperzine A is non-toxic even at doses 100 times the therapeutic dose.
www.naturalhealthconsult.com /Monographs/huperzine.html   (261 words)

  
 Doctor's Trust Huperzine A with Ginkgo, 60 capsule, 50/60 mcg/mg   (Site not responding. Last check: )
Huperzine A is the most exciting herbal memory aid scientists have unveiled since ginkgo biloba.
Huperzine A helps maintain healthy levels of acetylcholine in the brain, which is the important brain chemical involved in both memory and thought.
Doctor's Trust Huperzine A with Ginkgo is an ideal formula for helping those trying to stay sharp, focused, and at the top of their game.
www.doctorstrust.com /item/DT1301-1.html   (351 words)

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