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Topic: Hydrochloride

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In the News (Sat 20 Apr 19)

  Data Sheet
Naloxone hydrochloride, a narcotic antagonist, is a synthetic congener of oxymorphone.
Naloxone Hydrochloride Injection USP may be likely to produce minor or moderate adverse effects that may impair the patient's ability to concentrate and react and therefore constitute a risk in the ability to drive and use machines.
Naloxone hydrochloride occurs as a white to slightly off-white powder and is soluble in water, dilute acids and strong alkalis and is slightly soluble in alcohol.
www.medsafe.govt.nz /profs/Datasheet/n/Naloxonehydrochlorideinj.htm   (1699 words)

 FDA Approval for Erlotinib Hydrochloride - National Cancer Institute
Survival was significantly prolonged on the erlotinib hydrochloride arm with a
The study involved 569 patients with 521 patients in the erlotinib hydrochloride 100 mg cohort and 48 patients in the erlotinib hydrochloride 150 mg cohort.
Survival was significantly prolonged on the erlotinib hydrochloride arm with a median overall survival of 6.4 months and 6.0 months in the 100 mg erlotinib hydrochloride/gemcitabine and placebo/gemcitabine groups, respectively.
www.cancer.gov /cancertopics/druginfo/fda-erlotinib-hydrochloride   (1066 words)

 MedFriendly.com: Diphenhydramine hydrochloride
Diphenhydramine hydrochloride is available in capsule form, tablet form, syrup form, injectable form (through a muscle or vein), cream form, gel form, stick form, spray form, and in an elixir (a clear, sweet, part-alcoholic liquid that is taken by mouth) form.
The dose of diphenhydramine hydrochloride that should be taken varies according to the reason for why this medication is being taken, the form in which the medication is taken, the age of the person, and the weight of the person.
When using diphenhydramine hydrochloride to prevent motion sickness, it should be taken 30 minutes before traveling and 1 to 2 hours before being exposed to anything that would lead to motion sickness, such as sitting on a boat before traveling on it.
www.medfriendly.com /diphenhydramine.html   (2326 words)

 Doxorubicin Hydrochloride Liposome - National Cancer Institute
Doxorubicin hydrochloride liposome is also approved to be used with a drug called bortezomib to treat multiple myeloma after treatment with other chemotherapy.
Doxorubicin hydrochloride liposome is being studied in the treatment of other types of cancer.
Doxorubicin hydrochloride liposome is a form of doxorubicin hydrochloride contained inside liposomes (very tiny particles of fat).
www.cancer.gov /cancertopics/druginfo/doxorubicin-hydrochloride-liposome   (468 words)

 Sullivans Pharmacy, Boston, MA - home medical supplies - Respiratory equipment, Wheelchairs
Betahistine Hydrochloride is a drug resembling naturally occurring histamine in some of its effects and is used as a treatment for Menier's disease, a condition caused by the pressure of excess fluid in the inner ear.
When taken regularly Betahistine Hydrochloride can reduce the frequency and severity of the attacks of nausea and vertigo that characterise this condition and is thought to work by improving blood flow in the small blood vessels of the inner ear.
Betahistine Hydrochloride has not been demonstrated to have any effect on the evolution or progression of Meniere's disease and it appears not to eliminate the development of incapacitating vertigo and the subsequent need for surgery in some patients.
www.sullivanspharmacy.com /meniers.htm   (1350 words)

 Tramadol hydrochloride
The decrease in AUC was 14% for (+)-tramadol, 10.4% Tramadol hydrochloride for (-)-tramadol, 11.9% for (+)-M1 and 24.2% for (-)-M1.
Peak plasma Tramadol hydrochloride concentrations of acetaminophen occur within one hour and are Tramadol hydrochloride not affected by co-administration with tramadol.
Approximately 30% of the dose Tramadol hydrochloride is excreted in the urine as unchanged drug, whereas 60% of the dose Tramadol hydrochloride is excreted as Tramadol hydrochloride metabolites.
mywebpage.netscape.com /Rueben561/Tramadol-hydrochloride.html   (617 words)

 NTP: Abstract for TR-425 - Promethazine Hydrochloride
Promethazine hydrochloride is a drug used for the management of allergic conditions, motion sickness and nausea, and as a sedative to (treat psychiatric disorders.
Promethazine hydrochloride did not induce gene mutations in Salmonella typhimurium strains TA97, TA98, TA100, TA1535, or TA1537, or a significant increase in chromosomal aberrations in cultured Chinese hamster ovary cells; both of these tests were conducted with and without exogenous metabolic activation (S9).
Promethazine hydrochloride did not induce sex-linked recessive lethal mutations in germ cells of male Drosophila melanogaster administered the chemical by feeding or injection.
ntp-server.niehs.nih.gov /index.cfm?objectid=0709C7B1-BEBF-FF5A-3326AAF4ECDEF5C3   (1627 words)

 Ranbaxy Receives Tentative Approval to Manufacture and Market Cetirizine Hydrochloride Syrup   (Site not responding. Last check: )
Cetirizine Hydrochloride Syrup is indicated for the relief of symptoms associated with seasonal allergic rhinitis due to allergens such as ragweed, grass and tree pollens in adults and children 2 years of age and older.
Cetirizine Hydrochloride Syrup is also indicated for the relief of symptoms associated with perennial allergic rhinitis due to allergens such as dust mites, animal dander and molds in adults and children 6 months of age and older.
Cetirizine Hydrochloride Syrup is also indicated for the treatment of the uncomplicated skin manifestations of chronic idiopathic urticaria in adults and children 6 months of age and older.
www.prnewswire.com /cgi-bin/stories.pl?ACCT=104&STORY=/www/story/11-02-2006/0004465863&EDATE=   (495 words)

 Tramadol (28:08.08) - 395011
Tramadol hydrochloride extended-release tablets are used for the management of moderate to moderately severe pain (e.g., osteoarthritis-related pain, low back pain) when a continuous, around-the-clock analgesic is needed for an extended period of time.
For patients receiving tramadol hydrochloride conventional tablets alone for the relief of moderate to moderately severe pain and not requiring rapid onset of analgesic effect, the manufacturers recommend a dosage titration regimen to decrease the likelihood of discontinuance secondary to adverse effects (e.g., nausea, vomiting, dizziness, vertigo) associated with administration at higher initial dosages.
When tramadol hydrochloride is used in fixed combination with acetaminophen for the short-term (5 days or less) management of acute pain in patients 17 years of age and older, the usual dosage is 75 mg of tramadol hydrochloride every 4–6 hours as needed, up to a maximum of 300 mg daily.
www.ashp.org /mngrphs/ahfs/a395011.htm   (6677 words)

 Inclusion complex of nicardipine or its hydrochloride with beta-cyclodextrin and a sustained release pharmaceutical ...
The inclusion complex of nicardipine or its hydrochloride posesses cerebrovascular-vasodilatory and coronary-vasodilatory properties, which are equally well expressed as those of nicardipine or its hydrochloride themselves, yet owing to the better solubility of the complex at a higher pH range, such as it exists e.g.
The resemblance between the powder pattern of beta-cyclodextrin and that of the inclusion complex of nicardipine hydrochloride with beta-cyclodextrin is in that they both show the strongest lines for the spacings between the lattice planes in the ranges from 4.5 to 5.0 and from 6.5 to 7.0.
The DSC scans of nicardipine hydrochloride, beta-cyclodextrin, the physical mixture of nicardipine hydrochloride and beta-cyclodextrin and of the inclusion complex of nicardipine hydrochloride with beta-cyclodextrin clearly indicate the formation of the inclusion complex of nicardipine hydrochloride with beta-cyclodextrin.
www.freepatentsonline.com /5079237.html   (4153 words)

 Lidocaine Hydrochloride Official FDA information, side effects and uses.
Lidocaine Hydrochloride jelly, 2% is indicated for prevention and control of pain in procedures involving the male and female urethra, for topical treatment of painful urethritis, and as an anesthetic lubricant for endotracheal intubation (oral and nasal).
Lidocaine Hydrochloride jelly, 2% should be used with extreme caution in the presence of sepsis or severely traumatized mucosa in the area of application, since under such conditions there is the potential for rapid systemic absorption.
The oral LD50 of Lidocaine Hydrochloride in non-fasted female rats is 459 (346 to 773) mg/kg (as the salt) and 214 (159 to 324) mg/kg (as the salt) in fasted female rats.
www.drugs.com /pro/lidocaine-hydrochloride.html   (2892 words)

 EPA: Federal Register: Propamocarb Hydrochloride; Notice of Filing a Pesticide Petition to Establish a Tolerance for a ...
Propamocarb hydrochloride was previously classified as toxicity category III for acute oral and dermal toxicity and eye irritation, and category IV for acute inhalation toxicity and skin irritation.
As a professional use turf and ornamental fungicide, propamocarb hydrochloride is used primarily (>90% of use) on golf courses for control of Pythium blight (BANOL Fungicide, EPA Reg.
The toxicology database for propamocarb hydrochloride regarding potential prenatal and postnatal effects in children is complete according to existing Agency data requirements and does not indicate any particular developmental or reproductive concerns, therefore an additional UF to protect infants and children is not needed.
www.epa.gov /fedrgstr/EPA-PEST/2004/March/Day-10/p464.htm   (5355 words)

 CLONIDINE HYDROCHLORIDE TABLETS, USP Drug Information - Medicine Online
Clonidine hydrochloride, USP is a centrally acting alpha-agonist hypotensive agent available as tablets for oral administration in three dosage strengths: 0.1 mg, 0.2 mg and 0.3 mg.
Acute studies with clonidine hydrochloride in humans have demonstrated a moderate reduction (15% to 20%) of cardiac output in the supine position with no change in the peripheral resistance: at a 45° tilt there is a smaller reduction in cardiac output and a decrease of peripheral resistance.
As clonidine hydrochloride is excreted in human milk, caution should be exercised when clonidine hydrochloride is administered to a nursing woman.
www.medicineonline.com /drugs/C/3235/CLONIDINE-HYDROCHLORIDE-TABLETS-USP.html   (2205 words)

 Amiodarone Hydrochloride 50 mg/ml Sterile Concentrate , SPC from the eMC
Intravenous amiodarone hydrochloride is indicated only for the treatment of severe rhythm disorders not responding to other therapies or when other treatments cannot be used.
Amiodarone hydrochloride induces ECG changes: QT interval lengthening corresponding to prolonged repolarisation with the possible development of U and deformed T waves; these changes are evidence of its pharmacological action and do not reflect toxicity.
Amiodarone hydrochloride may increase the plasma levels of cyclosporin when used in combination, due to a decrease in the clearance of this drug.
emc.medicines.org.uk /emc/assets/c/html/displaydoc.asp?DocumentID=9321   (2803 words)

 Pharmaceutical compositions containing donepezil hydrochloride - Patent 6734195
A pharmaceutical composition according to claim 1 in which the amount of donepezil hydrochloride amorphous is between 1 to 30 mg.
Thus, it is described that at 40° C. the content of the impurities of crystalline donepezil hydrochloride (forms I to IV) did not change during a 12 week period, whereas the impurity content in amorphous donepezil hydrochloride changed from an initial value of 0.1% to 0.2% after 4 weeks and to 0.4% after 12 weeks.
Donepezil hydrochloride was dissolved in water and the solution was mixed with a mixture of lactose monohydrate, microcrystalline cellulose, maize starch and hydroxypropylcellulose.
www.freepatentsonline.com /6734195.html   (1248 words)

 Fluoxetine hydrochloride -induced pulmonary disease - Prozac CHEST - Find Articles   (Site not responding. Last check: )
She had been taking fluoxetine hydrochloride (20 to 60 mg daily) for 4 months On the presumption she had acute bronchitis, she was treated with bronchodilators and antibiotics, with slow symptom resolution.
In the interim 10 months, after other antidepressants failed to control her depression, treatment with these was discontinued and fluoxetine hydrochloride therapy was eventually restarted at 20 mg daily.
Suspecting that the fluoxetine hydrochloride may have triggered her condition, she discontinued treatment with it.
www.findarticles.com /p/articles/mi_m0984/is_n6_v107/ai_17111852   (733 words)

 Glucophage (Metformin Hcl) drug description - FDA approved labeling for prescription drugs and medications at RxList
GLUCOPHAGE® (metformin hydrochloride tablets) and GLUCOPHAGE® XR (metformin hydrochloride extended-release tablets) are oral antihyperglycemic drugs used in the management of type 2 diabetes.
Metformin hydrochloride is freely soluble in water and is practically insoluble in acetone, ether, and chloroform.
Metformin hydrochloride is combined with a drug release controlling polymer to form an "inner" phase, which is then incorporated as discrete particles into an "external" phase of a second polymer.
www.rxlist.com /cgi/generic/metformi.htm   (382 words)

 Abstract for TR-344 - Tetracycline Hydrochloride - National Toxicology Program
Tetracycline hydrochloride is a broad-spectrum antibiotic used for its bactericidal action in human and veterinary medicine.
Based on these results, 2-year studies of tetracycline hydrochloride were conducted by feeding diets containing 0, 12,500, or 25,000 ppm tetracycline hydrochloride to groups of 50 rats and 50 mice of each sex for 103 weeks.
Tetracycline hydrochloride was negative in the mouse lymphoma L5178Y/TK+/- assay with or without induced rat liver S9 but gave a marginally positive response when tested in the presence of noninduced S9.
ntp.niehs.nih.gov /index.cfm?objectid=07085276-B3E2-C702-7C6F26FAE2157677   (968 words)

 Aricept Drug Description - donepezil hydrochloride - HealthScout
ARICEPT® (donepezil hydrochloride) is a reversible inhibitor of the enzyme acetylcholinesterase, known chemically as (?±)-2,3-dihydro-5,6-dimethoxy-2-[[1-(phenylmethyl)-4-piperidinyl]methyl]-1H-inden-1-one hydrochloride.
Donepezil hydrochloride is commonly referred to in the pharmacological literature as E2020.
Donepezil hydrochloride is a white crystalline powder and is freely soluble in chloroform, soluble in water and in glacial acetic acid, slightly soluble in ethanol and in acetonitrile and practically insoluble in ethyl acetate and in n-hexane.
www.healthscout.com /rxdetail/1/113/1/main.html   (241 words)

 Betaine Hydrochloride Information on Healthline
Betaine hydrochloride is a synthesized chemical, and is not obtained from any plant or animal source.
Betaine hydrochloride has been used as a source of hydrochloric acid in the treatment of hypochlorhydria, a condition in which an abnormally low amount of hydrochloric acid is in the stomach.
Betaine hydrochloride has also been used to treat tic douloreux (a condition which involves spasmodic pain along the course of a facial nerve), cystinuria (a hereditary defect that results in recurrent kidney stone formation), and vitiligo (a condition that is characterized by milky-white patches on otherwise normal skin).
www.healthline.com /galecontent/betaine-hydrochloride   (796 words)

 Glucosamine Hydrochloride vs. Sulfate /Chondroitin
Glucosamine hydrochloride offers the promise of the same efficacy as glucosamine sulfate, since glucosamine is not absorbed intact with its carrier.
As a matter of clarification, while this study references glucosamine sulfate, it was actually glucosamine hydrochloride that was radiolabeled and used to prove the bioavailability of glucosamine.
We can conclude that since sulfate and hydrochloride are not the key building blocks for the production of joint cartilage, it makes no difference whether glucosamine has a sulfate or hydrochloride carrier, in terms of bioavailability.
www.chiro.org /nutrition/ABSTRACTS/Glucosamine_Update.shtml   (680 words)

 Dopamine Hydrochloride
Dopamine (Dopamine Hydrochloride) is the immediate precursor of epinephrine in the body.
Dopamine hydrochloride is a white to off-white crystalline powder, which may have a slight odor of hydrochloric acid.
Dopamine hydrochloride injection is a clear, practically colorless, sterile, pyrogen-free, aqueous solution of dopamine HCl for intravenous infusion after dilution.
www.greatvistachemicals.com /pharmaceutical_intermediates/dopamine_hydrochloride.html   (291 words)

 [No title]
Fexofenadine hydrochloride is a white to off-white crystalline powder.
Fexofenadine hydrochloride is a racemate and exists as a zwitterion in aqueous media at physiological pH.
In 2 separate studies, fexofenadine hydrochloride 120 mg twice daily (240 mg total daily dose) was co-administered with either erythromycin 500 mg every 8 hours or ketoconazole 400 mg once daily under steady-state conditions to healthy volunteers (n=24, each study).
www.lycos.com /info/fexofenadine--fexofenadine-hydrochloride.html   (370 words)

 Betaine and Betaine Hydrochloride
The hydrochloride of betaine is known as betaine hydrochloride, betaine HCL and pluchine.
Betaine hydrochloride is a delivery form of hydrochloric acid and may aid in digestion in some.
Betaine hydrochloride is converted to betaine in the alkaline environment of the small intestine.
www.pdrhealth.com /drug_info/nmdrugprofiles/nutsupdrugs/bet_0331.shtml   (1663 words)

 19890112 Human Exposure and Adverse Drugs Reaction from Vetalor (ketamine hydrochloride).   (Site not responding. Last check: )
DESCRIPTION Vetalar (ketamine hydrochloride) is a rapid-action, nonnarcotic, nonbarbiturate agent for anesthetic use in cats and for restraint in subhuman primates.
It is chemically designated at 2-(o-chlorophenyl)-2-(methylamino) cyclohexanone hydrochloride and is supplied as a slightly acid (pH 35 to 55) solution for intramuscular injection in a concentration containing the equivalent of 100 mg ketamine base per milliliter and contains not more than 01 mg/ml Phemerol (benzethonium chloride) as a preservative.
Vetalar (Ketamine Hydrochloride Injection, USP) As with other anesthetic agents, the individual response to Vetalar is somewhat varied depending upon the dose, general condition, and age of the subject so that dosage recommendations cannot e absolutely fixed.
www.osha.gov /dts/hib/hib_data/hib19890112.html   (1651 words)

 Hydrochloride - Wikipedia, the free encyclopedia
Even though this style of formulas is often used for denoting the hydrochlorides, the dot incorrectly implies that the two molecules are weakly bonded together.
The typical breadth of time needed for a hydrochloride to be absorbed thusly is 15-30 minutes.
Examples of what they are medically used for are ubiquitous ranging from over-the-counter sinus relief to antinausea medication used mainly in the treatment of chemotherapy-induced nausea and vomiting (Zofran, Ondansetron hydrochloride).
en.wikipedia.org /wiki/Hydrochloride   (189 words)

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