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Topic: Hydrogel

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	World Intellectual Property Organization (Site not responding. Last check: 2007-10-15)
		Hydrogel is used to improve the effectiveness of skincare, and is produced in a form of a sheet or a patch to be effectively applied to the skin.
		In the hydrogel composition of the present invention, the branched gelation polymer and electrolyte gelation polymer are used as the gel forming substance.
		When the hydrogel sheet or patch of the present invention is applied to the skin, hydrogel is transformed from the gel state to the fluid state due to the body temperature.
	www.wipo.int /ipdl/IPDL-CIMAGES/view/pct/getbykey5?KEY=05/16305.050224&ELEMENT_SET=DECL (3335 words)

	The Whitaker Foundation: Growing Nerve Cells in the Laboratory (Site not responding. Last check: 2007-10-15)
		Hydrogels are made up mostly of water but have the physical properties of a solid, like Jell-O or soft contact lenses.
		The researchers chose hydrogel as a scaffold material because the substance is soft and closely matches the mechanical properties of soft nerve tissue.
		Because they are mostly water, biodegradable hydrogel scaffolds would be readily absorbed by the body.
	www.whitaker.org /news/shoichet2.html (507 words)

	Feature
		Hydrogel dressings reduce pain by cooling and covering the open nerve endings and thus are very useful in plastic surgery.
		Hydrogel dressings hydrate the desiccated wounds which is essential for healing.
		If dried on the wound, hydrogel dressing should be rehydrated by first wetting the dressing, using boiled, cooled or distilled water for 10 to15 minutes to ensure a painless removal of the dressing.
	pib.nic.in /feature/feyr2003/fsep2003/f290920031.html (1064 words)

	Patent 6,203,845
		The dehydrated hydrogel produced by the method of the invention may be in the form of a film having a thickness of, for example, 20 microns to 10 mm.
		In a typical method of preparing a dehydrated hydrogel in accordance with the invention, the fibres, polymer and plasticiser in their relative requisite amounts are admixed with water such that the fibres, polymer and plasticiser together provide less than 5% by weight (e.g.
		Dehydrated hydrogels produced in accordance with the method of this invention may be laminated to hydrophilic films which have an increased breathability in the presence of liquid water as compared to moisture vapour alone.
	www.pharmcast.com /Patents/Yr2001/March2001/032001/6203845_Hydrogel032001.htm (1060 words)

	World Intellectual Property Organization (Site not responding. Last check: 2007-10-15)
		Preferably, the hydrogel composition forms a gel that is substantially insoluble in water under physiological conditions, whereby the hydrogel is not washed away by the wound fluid.
		The hydrogel material may further comprise from 5 to 50% by weight on a dry weight basis of one or more humectants such as glycerol For example, the hydrogel layer comprise a hydrogel material of the kind described in WO00/07638, the entire content of which is incorporated herein by reference.
		The hydrogel and foam sheets are allowed to cure partially for about 90 seconds at ambient temperature, and then the foam layer is pressed gently onto the hydrogel in the cover sheet and the combination is placed in an oven for about 15 minutes to complete the curing and drying.
	www.wipo.int /ipdl/IPDL-CIMAGES/view/pct/getbykey5?KEY=03/86255.031023&ELEMENT_SET=DECL (3931 words)

	Anterior capsule contraction and intraocular lens decentration and tilt after hydrogel lens implantation -- Hayashi et ...
		IOL, and the degree of IOL decentration and tilt.
		The mean percentage of the area reduction in the hydrogel group was significantly greater than that in the acrylic group at 3 and 6 months after surgery.
		Hydrogel materials are reported to be highly biocompatible in terms of their hydrophilic properties.
	bjo.bmjjournals.com /cgi/content/full/85/11/1294 (2535 words)

	Microscopic hydrogel chambers facilitate drug screenings
		Microscopic chambers constructed of a hydrogel similar to Jell-O, may allow pharmaceutical chemists to screen chemical libraries of molecules rapidly for potential new drugs, according to a Penn State chemical engineer.
		Then the 3-dimensional poly (ethylene) glycol hydrogel microstructures are fabricated in the microfluidic channels using a photo mask and light, which sets the gel.
		Because the hydrogel is transparent, a variety of optical sensors can also be used on chambers in the biochip.
	www.eurekalert.org /pub_releases/2002-04/ps-mhc040402.php (541 words)

	Insertion of hydrogel keratoprosthesis
		The implantation of a synthetic hydrogel cornea is a two-stage surgical procedure.
		The superficial flap is then reflected to allow a portion of the central part of the posterior lamella to be removed using a trephine, and the synthetic hydrogel cornea to be inserted into the intralamellar pocket.
		The second stage of the procedure is performed 12 weeks later, and involves removing the conjunctival cover and the superficial flap of the cornea exposing the synthetic hydrogel cornea to light.
	www.nice.org.uk /cms/ip/ipcat.aspx?o=80299 (447 words)

	Stable, aqueous cationic hydrogel - US Patent 6667029 (Site not responding. Last check: 2007-10-15)
		A stable, aqueous cationic hydrogel of, by weight, 1-50% of a crosslinked cationic copolymer of 5-95% vinylpyrrolidone (VP) and 5-95% 3-dimethylaminopropyl(meth)acrylamide (DMAPMA) monomers, a crosslinking agent in an amount of 0.05-1% of said monomers, and water is described.
		A cationic hydrogel according to claim 1 in which said crosslinking agent is present in an amount of 0.1-0.5%.
		The cationic hydrogel of the invention, at a pH of 3-9, preferably 4-8, is useful as a viscosity modifier or swelling agent.
	www.patentstorm.us /patents/6667029.html (1919 words)

	Technique creates patterns in unique photonic crystals
		Hydrogel photonic crystal samples composed of various particle types and sizes are shown.
		Before the hydrogel nanoparticles can be useful in photonic applications, however, the researchers must reduce the size of the spheres and refine the technology to create smaller features.
		The temperature at which the particles transition to a crystalline state can be controlled chemically during the synthesis process in a range from 10 degrees C to 60 degrees C. After synthesis and precipitation polymerization in aqueous media, the particles are separated from the surrounding water by simple centrifuging.
	gtresearchnews.gatech.edu /newsrelease/patterning.htm (1151 words)

	Vetalintex Wound Hydrogel Launched - Horse News from the Equiworld Magazine - February 2002
		Using a hydrogel can help to maintain a moist wound environment, considered to be important for the healing process to take place at the optimum rate.
		Hydrogel dressings are not suitable for heavily infected wounds which should always be treated under veterinary supervision.
		Vetalintex Wound Hydrogel together with a free information leaflet on moist wound healing is available from your veterinary surgeon or from most equestrian and agricultural retail outlets.
	www.equiworld.net /uk/ezine/0202/robinsoncare.htm (263 words)

	Patent 6,124,273
		In another embodiment, this invention provides a composition of matter that promotes the directed migration of animal cells, comprising: a hydrogel; and an effective concentration of at least one growth factor, wherein the concentration of the growth factor is effective in promoting the directed migration of the animal cells.
		In another embodiment, this invention provides a simple to use, fast acting, field-ready bandage for applying a hydrogel to wounded tissue in a patient, comprising an occlusive backing, affixed to which is a layer of dry materials comprising an effective amount of dry, purified chitin or chitosan to produce a tissue-sealing hydrogel matrix upon hydration.
		A sixth advantage is that the antibiotic-supplemented hydrogel of this invention, such as with TET, has been found to unexpectedly increased the longevity and stability of the chitin hydrogen, as compared to that of the unsupplemented hydrogel.
	pharmcast.com /Patents/September2000/092600OG/6124273_Chitin092600.htm (2214 words)

	It’s half time, bring on the hydrogel
		A potential alternative form of treatment would be to introduce a hydrogel into the knee to support the damaged meniscus and promote the formation of new cartilage, and a number of research groups have studied various hydrogels for this purpose.
		To create their hydrogel, the researchers combined HA with the photoreactive compound methacrylic anhydride to produce methacrylated HA (MeHA), and then mixed this with the photosensitive compound poly(ethylene glycol) dimethacrylate.
		After discovering that an excess of MeHA in the hydrogel makes it less able to support tissue cells, the researchers were able to create a hydrogel that could support encapsulated cartilage-producing cells known as chondrocytes.
	www.rsc.org /chemistryworld/Issues/2005/February/hydrogel.asp (343 words)

	Posterior capsule opacification after implantation of a hydrogel intraocular lens -- Hayashi and Hayashi 88 (2): 182 -- ...
		The PCO value in the hydrogel group increased significantly, while the change in the PCO value was not significant in the acrylic group.
		Mean visual acuity in the hydrogel group was worse than that in the acrylic group; this difference was significant at 18 and 24 months after surgery.
		In an eye with a hydrogel IOL (A), fibrosis of the anterior capsule along the capsulorrhexis margin is marked.
	www.bjophthalmol.com /cgi/content/full/88/2/182 (2738 words)

	Hydrogel Impregnated Gauze
		Wound gels are excellent for helping to create or maintain a moist environment Some hydrogels provide absorption, desloughing and debriding capacities to necrotic and fibrotic tissue.
		Hydrogel sheets are cross-linked polymer gels in sheet form.
		Hydrogel wound cover (gauze or sheet) is usually changed once per day.
	www.medicaledu.com /hydrogelgauze.htm (156 words)

	Ameda Hydrogel
		Soft hydrogel pads provide cool, soothing relief for mothers who may be experiencing nipple pain or trauma associated with breastfeeding.
		Hydrogel pads provide a moist healing environment and help absorb leakage to keep skin healthy and to help the nipple area remain dry between feedings.
		With a low profile and contoured design, the hydrogel pads fit discreetly under a nursing bra.
	www.duematernity.com /amedahydrogel.html (92 words)

	Protesi mammarie all' hydrogel
		Le protesi mammarie in hydrogel sono riempite con un materiale polimerico, che, immerso in acqua, ha la capacità di gonfiarsi e formare un gel trattenendo liquido.
		Esistono numerosi tipi di hydrogel, tra cui quelli usati per le lenti a contatto, ma quelli impiegati nelle protesi mammarie sono sostanzialmente due: il PVP, polivinilpirrolidone, usato nelle protesi NovaGold e precedentemente nelle MistiGold, e l' idrossipropilcellulosa impiegata nelle protesi PIP Hydrogel.
		Il fatto che la relativa documentazione clinica sia inferiore rispetto a quella ormai disponibile per le protesi in silicone o con soluzione fisiologica le rende comunque, almeno nella nostra opinione, una scelta priva di sostanziali vantaggi e dotata, invece, di qualche incertezza sul comportamento del gel a distanza di anni.
	www.chirurgiaestetica.com /news/hydrogel.htm (357 words)

	Hydrogel Breast Implants Information
		PIP Hydrogel bre ast implants come in smooth and textured surfaces, as well as standard and high profile.
		Hydrogels are said to feel very much like natural breast tissue, but cost $400-$1500 more than other implants do.
		Basically, the same concerns regarding the PVP Hydrogel implants are the same as the concerns about the PIP Hydrogels, as well as the lack of data to assess risks arising from the implantation of guar gum.
	www.justbreastimplants.com /implants/hydrogel.htm (418 words)

	001211e-hss HYDROGEL BREAST IMPLANTS WITHDRAWN Department of Health, Social Services and Public Safety 11 December 2000 (Site not responding. Last check: 2007-10-15)
		PIP Hydrogel® breast implants are made in France and supplied here by Clover Leaf Products Ltd. Approximately 4000 women in Scotland, England, Wales and here have received these implants since they were first introduced in 1994.
		Women who think that they may have hydrogel breast implants and are concerned should contact the surgeon who carried out their operation, or their GP or get advice from the Health Information Service on 0800 66 5544.
		Hydrogels are polymeric materials that have the ability to swell in water without dissolving and retain water within their structures.
	www.nics.gov.uk /press/hss/001211e-hss.htm (1134 words)

	Editorial - Protein and Lipid Deposition of Silicone-Hydrogel Contact Lens Materials
		Detailed explanations of the development of silicone hydrogel materials for contact lenses and their polymer chemistry have been described in detail elsewhere.
		The use of silicon-containing flexible contact lenses is not new, as silicone-elastomeric lenses have been used for therapeutic and paediatric applications for many years.
		The adsorption of proteins and lipids at the contact lens interface is dependent upon a number of factors.
	www.siliconehydrogels.org /editorials/previous_editorial_jones_senchyna.asp (1999 words)

	Today's SurgiCenter - CardioTech Announces FDA Clearance of Antibiotic Hydrogel Wound and Burn Dressing
		The CardioTech hydrogel dressing is a unitary construction that is absorbent, with reduced tendency to adhere to skin lesions.
		With hydration, the hydrogel forms intimate contact with the wound, minimizing dead space, and because it does not adhere to tissue, the removal is atraumatic and painless.
		The hydrogel dressing maintains a "moist wound environment" which aids in healing, and the medication is an aid in the prevention of bacterial infection.
	www.surgicenteronline.com /hotnews/31h782813.html (481 words)

	775 (Site not responding. Last check: 2007-10-15)
		c-PVA hydrogel was prepared from saponified copolymers of vinyl acetate and triallyl isocyanurate by exposure to ultraviolet light.
		Hydrogels were individually kept in the 0.5 w/v% lysozyme solution at 37 °C for 24 hours.
		The lysozyme adsorbed to hydrogels was extracted with 1 w/v% sodium dodecyl sulfonate (SDS) respectively.
	www.csj.jp /journals/nikka/abs/nikka9911/nk99775a.html (156 words)

	Hydrogel-Based Nanoparticles Make Photonic Crystals
		Lyon and his colleagues have fabricated nearly 100 different types of monodisperse hydrogel particles, in sizes ranging from 50 nanometers to 1 micron in diameter.
		The temperature at which the particles transition to a crystalline state can be controlled chemically during the synthesis process in a range from 10 degrees C to 60 degrees C. The nanoparticles are synthesized from poly-N-isopropylacrylamide (pNIPAm) lightly cross-linked with N,N-methylenebis(acrylamide)(BIS).
		This thermal cycling process serves to pack the soft hydrogel particles into an ordered 3-D hexagonal array, which produces the periodic dielectric structure needed for optical properties.
	unisci.com /stories/20022/0418022.htm (898 words)

	Hydrogel - Wikipedia, the free encyclopedia
		Hydrogel is a network of polymer chains that are water-soluble, sometimes found as a colloidal gel in which water is the dispersion medium.
		Hydrogels are superabsorbent (they can contain over 99% of water) natural or synthetic polymers.
		medical electrodes using hydrogels composed of cross linked (polyethylene oxide, polyAMPS and polyvinylpyrrolidone)
	en.wikipedia.org /wiki/Hydrogel (133 words)

	In vitro and in vivo study of lens refilling with poloxamer hydrogel -- Han et al. 87 (11): 1399 -- British Journal of ...
		In vitro and in vivo study of lens refilling with poloxamer hydrogel -- Han et al.
		The gelling temperature of the poloxamer hydrogel was
		refractive index of the poloxamer hydrogel was 1.36.
	bjo.bmjjournals.com /cgi/content/full/87/11/1399 (1849 words)

	BD Biosciences
		BD™ PuraMatrix™ Peptide Hydrogel is a synthetic matrix that is used to create defined three-dimensional (3D) microenvironments for a variety of cell culture experiments.
		Hydrogel is readily formed in a culture dish, plate, or cell culture insert
		The cell-bearing hydrogels were transferred to dishes with fresh medium.
	www.bdbiosciences.com /discovery_labware/Products/tissue_engineering/PuraMatrix (820 words)

	Cornell News: biodegradable hydrogels
		The hydrogels not only are useful for controlling and delivering medications and serving as biodegradable networks for implants, tissue engineering and regeneration but also may have applications for coatings in agricultural products.
		In one of the new hydrogel inventions from his lab, Chu combined dextran and maleic acid to develop one type of hydrogel that can increase its swelling without lessening its structural stability and mechanical strength.
		About the other new class of hydrogel inventions from his lab that has both polysaccharide and synthetic biodegradable components, Chu says: "We have found that the release profile of medications is not only controlled by molecular weight but also by manipulating the composition ratio of these two hydrogel components.
	www.news.cornell.edu /releases/Nov99/hydrogel.advances.ssl.html (736 words)

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