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Topic: Hydromorphone

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	HYDROMORPHONE (Trade name: Dilaudid®; Street Names: Dust, Juice, Smack, D, Footballs)
		Hydromorphone is used for relief of moderate to severe pain in patients where an opioid analgesic is appropriate.
		Hydromorphone, [4,5-epoxy-3-hydroxy-17-methylmor-phinan-6-one, dihydrohydroxycodeinone; dihydromorphinone; dimorphone] is a semi-synthetic opioid agonist derived from morphine.
		Abuse of hydromorphone is mainly among rural and suburban populations.
	www.deadiversion.usdoj.gov /drugs_concern/hydromorphone.htm (710 words)

	Hydromorphone hydrochloride patient advice including side effects
		Hydromorphone hydrochloride may impair the mental and/or physical abilities required for the performance of potentially hazardous tasks such as driving a car or operating machinery.
		Hydromorphone hydrochloride should be used with caution if you are in a weakened condition or if you have a severe liver or kidney disorder, hypothyroidism (underactive thyroid gland), Addison's disease (adrenal gland failure), severe lung problems, an enlarged prostate, a urethral stricture (narrowing of the urethra), low blood pressure, or a head injury.
		Hydromorphone hydrochloride suppresses the cough reflex; therefore, the doctor will be cautious about prescribing Hydromorphone hydrochloride after an operation or for patients with a lung disease.
	www.drugs.com /pdr/HYDROMORPHONE_HYDROCHLORIDE.html (1399 words)

	Hydromorphone - Wikipedia, the free encyclopedia
		Hydromorphone is often sought after by opiate drug abusers as it is one of the most potent of all prescription narcotics, when taken parenterally.
		Hydromorphone, a semi-synthetic μ-opioid agonist, is a hydrogenated ketone of morphine and shares the pharmacologic properties typical of opioid analgesics.
		Hydromorphone, Ketobemidone, Morphine, Nalbuphine, Oxycodone, Oxymorphone, Pentazocine, Pethidine (Meperidine), Tramadol
	en.wikipedia.org /wiki/Hydromorphone (525 words)

	Hydromorphone Tablets - Drugs & Vitamins - Drug Library - DrugDigest (Site not responding. Last check: 2007-10-11)
		Hydromorphone may also be used to treat pain associated with cancer, heart attacks, sickle cell disease and other medical conditions.
		Rarely, hydromorphone may cause you to have hallucinations (to see things that are not really there) or cause your legs or arms to "jerk" or have spasms.
		Avoid accidental swallowing of hydromorphone by someone (especially children) other than the person for whom it was prescribed as this may result in severe effects and possibly death.
	drugdigest.org /DD/DVH/Uses/0,3915,331\|Hydromorphone+Tablets,00.html (897 words)

	hydromorphone - Drug Finder - MSN Health & Fitness (Site not responding. Last check: 2007-10-11)
		An extended-release form of hydromorphone should not be the first narcotic pain medication that has been prescribed to you and should not be used if you will only need pain medicine for a short time or will only be using it occasionally (as needed).
		Hydromorphone is habit forming and should only be used under close supervision if you have an alcohol or drug addiction.
		Hydromorphone is in the FDA pregnancy category C. This means that it is not known whether it will be harmful to an unborn baby.
	health.msn.com /drugfinder/articlepage.aspx?cp-documentid=100059734 (1582 words)

	ACS :: Cancer Drug Guide: hydromorphone
		Hydromorphone relieves moderate to severe pain and is similar to morphine.
		Hydromorphone is given in a number of ways.
		Since hydromorphone affects the central nervous system, it is important not to take other drugs or substances that are known CNS depressants such as alcohol, sedatives, and hypnotics.
	www.cancer.org /docroot/CDG/content/CDG_hydromorphone.asp (723 words)

	hydromorphone Consumer Drug Information
		Hydromorphone should never be given to another person, especially someone who has a history of drug abuse or addiction.
		Hydromorphone rectal is used to treat moderate to severe pain.
		Since hydromorphone is sometimes used as needed, you may not be on a dosing schedule.
	www.drugs.com /MTM/hydromorphone.html (1700 words)

	RemedyFind: patient ratings of Dilaudid etc. (Hydromorphone) for Fibromyalgia Syndrome (FMS; FM) (Site not responding. Last check: 2007-10-11)
		Hydromorphone is 7-10 times more analgesic than morphine, with a shorter duration of action.
		Hydromorphone is available in many forms: as tablets; liquid; suppository; and as an injectable solution.
		Hydromorphone (Dilaudid/Palladon) is very effective in reducing or eliminating acute or chronic pain, especially if your body does not respond to morphine, such as mine.
	www.remedyfind.com /treatments/10/1387 (601 words)

	Hydromorphone
		Hydromorphone (Dilaudid®) is marketed in tablets (2, 4, and 8 mg), rectal Suppositories, oral solutions, and injectable formulations.
		Much sought after by narcotic addicts, hydromorphone is usually obtained by the abuser through fraudulent prescriptions or theft.
		The tablets are often dissolved and injected as a substitute for heroin.
	www.streetdrugs.org /hydromorphone.htm (80 words)

	Pharmacy Times: COMPOUND IT!
		Hydromorphone is important because its metabolites are considered inactive, although renal failure patients may exhibit neuroexcitation possibly related to accumulated hydromorphone-3-glucuronide metabolite.
		Hydromorphone is not a firsttier medication, however, because of its higher cost relative to morphine.
		Thus, hydromorphone is reserved for those patients that do not tolerate less expensive opiates for one reason or another.
	www.pharmacytimes.com /article.cfm?ID=3430 (410 words)

	Health Report - 28 January 2002 - Hydromorphone Trials
		Hydromorphone is an injectable opioid that has similar effects to heroin.
		Wayne Hall: Hydromorphone is an opioid drug, commonly known as Dilaudid that is short-acting, like heroin, and produces a lot of the same effects as heroin.
		I think the conditions under which Hydromorphone would be prescribed in the type of trial we had in mind would be the same as in Switzerland, that is the drug would only be administered on site under medical supervision; there'd be no take-away doses.
	www.abc.net.au /rn/healthreport/stories/2002/469267.htm (1294 words)

	The addition of hydromorphone to epidural fentanyl does not affect analgesia in early labour: [L'addition ...
		The addition of hydromorphone to epidural fentanyl does not affect analgesia in early labour: [L'addition d'hydromorphone a l'injection epidurale de fentanyl n'affecte pas l'analgesie au debut du travail] -- Parker et al.
		a hydromorphone analgesia duration of 165 ± 45
		analgesic duration of hydromorphone in labour is not significantly
	www.cja-jca.org /cgi/content/full/49/6/600 (2450 words)

	Dilaudid, Hydromorphone, Narcotics, Analgesics, Pain Killers Drug & Medication Indexes On The Nursefriendly
		Dilaudid (Hydromorphone Hydrochloride): Health Sqaure: "Dilaudid a narcotic analgesic, is prescribed for the relief of moderate to severe pain such as due to.
		Hydromorphone HCl is hydrogenated ketone of morphine which is a narcotic analgesic.
		Although hydromorphone is widely used in North America, no study has compared the analgesic efficacy, side effect profiles and patients' satisfaction with the method of injection of hydromorphone s.c.
	www.jokesnjokes.net /skinner/drugs.medications.index/narcotics.analgesics.pain.killers/dilaudid.hydromorphone.htm (1066 words)

	An Omnipresent Risk of Morphine-Hydromorphone Mix-ups
		ISMP Canada recently received an error report in which a 69-year-old patient was given 10 mg of hydromorphone IM instead of 10 mg of morphine.
		For example, since both drugs are available in 2 mg and 4 mg prefilled syringes (in the US), stock 2 mg of hydromorphone and 4 mg of morphine (but not vice versa, since 4 mg of hydromorphone could be an excessive dose).
		Educate staff about the differences between hydromorphone and morphine, as some of the reported mix-ups have been due to the mistaken belief that hydromorphone is the generic name for morphine.
	www.ismp.org /MSAarticles/morphine.htm (729 words)

	Purdue Begins Shipment of Palladone (hydromorphone HCl extended-release) Capsules (CII)
		While long-acting (q12h) hydromorphone formulations are available in Canada, the United Kingdom, and Germany, Palladone is the first long-acting hydromorphone formulation available in the U.S. The product offers the convenience of once-daily (q24h) dosing and will be available in 12 mg, 16 mg, 24 mg, and 32 mg dosage strengths.
		Palladone™ (hydromorphone HCl extended-release) Capsules are indicated for the management of persistent, moderate to severe pain in patients requiring continuous, around-the-clock analgesia with a high potency opioid for an extended period of time (weeks to months) or longer.
		Schedule II opioid agonists (which include hydromorphone, fentanyl, methadone, morphine, oxycodone, and oxymorphone), have the highest risk of fatal overdoses due to respiratory depression, as well as the highest potential for abuse.
	www.pharma.com /pressroom/news/20050107-02.htm (1553 words)

	Palladone (Hydromorphone Hydrochloride Extended-Release) Capsules: Questions and Answers
		Palladone is used to treat adults (18 years of age and older) with persistent pain that is moderate-to-severe in intensity, which requires around the clock opioid pain relief for an extended period of time.
		Alcohol when taken with Palladone may cause too much hydromorphone to be released into the blood at once, which is called “dose-dumping.” This can result in respiratory depression, serious injury, coma, or death.
		Purdue Pharma completed a study in 24 healthy men that showed that, compared to taking Palladone by itself, concentrations of hydromorphone in the blood were 5.5 times higher when the 12 mg Palladone extended release capsules (the lowest dose available) were taken with 8 ounces of 40% alcohol.
	www.fda.gov /cder/drug/infopage/palladone/palladoneQA.htm (823 words)

	Hydromorphone for acute and chronic pain
		While hydromorphone appears to be a potent analgesic, evidence to date does not support its superiority over morphine for the management of moderate to severe pain.
		Of the remainder, hydromorphone was compared with other opioids (morphine, fentanyl, sufentanyl, meperidine, oxycodone, diamorphine), bupivicaine and with itself, using different formulations.
		However, the majority demonstrated that hydromorphone is a potent analgesic, that the clinical effects of hydromorphone appear to be dose-related, and that the adverse effect profile of hydromorphone is similar to that of other mu opioid receptor agonists.
	www.cochrane.org /reviews/en/ab003447.html (538 words)

	Hydromorphone Hydrochloride Injection
		The drug will be either injected into a large muscle (such as your buttock or hip) or added to an intravenous fluid that will drip through a needle or catheter placed in your vein or under your skin.
		If you are receiving hydromorphone intravenously (in your vein), you probably will be told to store it in the refrigerator.
		If you are receiving hydromorphone in your vein or under your skin, you need to know the symptoms of a catheter-related infection (an infection where the needle enters your vein or skin).
	www.safemedication.com /displaydrug.cfm?id=601148 (726 words)

	Inhibition of Cytochrome P450 2D6 Metabolism of Hydrocodone to Hydromorphone Does Not Importantly Affect Abuse ...
		Hydromorphone HCl and quinidine sulfate tablets were obtained as generic products from The Drug Trading Co. Ltd.
		Hepatic conversion of hydrocodone to hydromorphone is of almost no consequence in determining the effects of hydrocodone.
		Although the receptor binding of hydromorphone is greater than that of hydrocodone (Hennies et al.
	jpet.aspetjournals.org /cgi/content/full/281/1/103 (4167 words)

	Hydromorphone
		Hydromorphone is a semisynthetic narcotic and analgesic that is available in a variety of forms for oral, parenteral and rectal administration typically in doses of 1 — 4 mg as the hydrochloride.
		It is prescribed both as an antitussive and analgesic.
		About 6% of a dose is excreted as free and 30% as conjugated hydromorphone in a 24 hour.
	www.sdrl.com /druglist/hydromorphone.html (221 words)

	Dilaudid Online, Description, Chemistry, Ingredients - Hydromorphone Hydrochloride - RxList Monographs
		WARNING: DILAUDID ORAL LIQUID AND DILAUDID 8 MG TABLETS CONTAIN HYDROMORPHONE, WHICH IS A POTENT SCHEDULE II CONTROLLED OPIOID AGONIST.
		DILAUDID (hydromorphone hydrochloride), a hydrogenated ketone of morphine, is an opioid analgesic.
		The chemical name of DILAUDID (hydromorphone hydrochloride) is 4,5
	www.rxlist.com /cgi/generic/hydromorphone.htm (201 words)

	Palladone Extended Release Capsules (hydromorphone)
		FDA has issued a public health advisory to inform patients and health care providers that the sponsor of Palladone, Purdue Pharma, has agreed to suspend sales and marketing of Palladone (hydromorphone hydrochloride, extended release capsules), a potent narcotic painkiller, because of the potential for severe side effects if Palladone is taken with alcohol.
		Pharmacokinetic data indicate that the co-ingestion of Palladone and alcohol results in dangerous increases in the peak plasma concentrations of hydromorphone.
		FDA approved Palladone (hydromorphone hydrochloride extended-release) Capsules for the management of persistent, moderate to severe pain in patients requiring continuous, around-the-clock opioid analgesia with a high potency opioid for an extended period of time generally weeks to months or longer.
	www.fda.gov /cder/drug/infopage/palladone/default.htm (134 words)

	Hydromorphone overdose
		This is poisoning from taking an excessive amount of hydromorphone, a prescription medicine used to relieve severe pain.
		Hydromorphone is an opioid narcotic, which means it is an extremely powerful drug that can cause very deep sleep.
		Patients who are prescribed hydromorphone for pain should not drink alcohol.
	www.pennhealth.com /ency/article/002633.htm (391 words)

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