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Topic: Hydroxylapatite


In the News (Mon 8 Sep 08)

  
  Reference.com/Encyclopedia/Hydroxylapatite
Hydroxylapatite is the hydroxyl endmember of the complex apatite group.
Carbonated-calcium deficient hydroxylapatite is the main mineral of which dental enamel and dentin are comprised.
Coral skeletons can be transformed into hydroxylapatite by high temperatures; their porous structure allows relatively rapid ingrowth at the expense of initial mechanical strength.
www.reference.com /browse/wiki/Hydroxylapatite   (586 words)

  
 eMedicine - Middle Ear, Ossiculoplasty : Article by Robert A Battista, MD, FACS
Hydroxylapatite is currently one of the most common alloplastic materials used for ossicular reconstruction.
Hydroxylapatite is a polycrystalline calcium phosphate ceramic that has the same chemical composition as bone.
The crural notches on the base of the shaft are aligned on the stapes, the malleus is lifted with a pick, and the head of the prosthesis is engaged on the mid portion of the manubrium.
www.emedicine.com /ent/topic219.htm   (7089 words)

  
 Forum on Opportunistic Infections: Bioform for facial wasting
It is made of calcium hydroxylapatite which has safely been used in the body for many applications including dental applications where bone build-up is needed for reconstruction and also in block form for cosmetic applications such as cheek, jaw, cranial and chin implants.
The manufacturer claims that calcium hydroxylapatite creates a lattice where the surrounding cells can be incorporated from ossification in bony areas to a stable scaffold in which soft tissue can grow.
The manufacturer also claims that with Radiance, the calcium hydroxylapatite microspheres are suspended in a polysaccharide carrier which holds the microspheres in place until it is resorbed and the collagenation takes place.
www.thebody.com /Forums/AIDS/Infections/Archive/Lipodystrophy/Q147295.html   (823 words)

  
 Phosphate recovery at The Natural History Museum
The precipitation of dicalcium phosphate dihydrate (DCPD) onto hydroxylapatite (HAP) seeding crystals was studied at a temperature of 37°C and a pH of 4.5-5.0 (pH-stat method).
The precipitation of hydroxylapatite (Ca HAP) is preceded by the precipitation of amorphous calcium phosphate (Ca)*xH
The dissolution-rate of synthetic hydroxylapatite was measured in pure water at a temperature of 25C at a constant pH in the range 6.6-7.2, using the pH stat method.
www.nhm.ac.uk /research-curation/projects/phosphate-recovery/abstracts.htm   (7622 words)

  
  Standard Reference Material, SRM 2910 Calcium Hydroxylapatite {Ca10(PO4)6(OH)2}
SRM 2910 is a high-purity powder form of calcium hydroxylapatite with crystal sizes of about 0.1 µm to 0.5 µm.
Source of Material: The calcium Hydroxylapatite was synthesized at NIST by solution reaction of calcium oxide and phosphoric acid in accordance with the procedure of McDowell et al.
The resulting calcium Hydroxylapatite [6,7] is composed of about 75 % (by mass) of the hexagonal form (space groups P63/m or specifically P63 [8]) and of about 25 % (by mass) of the monoclinic form (space group P21/b [9]).
polymers.nist.gov /Biomedical-Materials-Reference-Data/Standard-Reference-Material-SRM2910-Calcium-Hydroxylapatite.html   (1749 words)

  
  Delivery system for implantation of fine particles in surgical procedures - Patent 4657548
It is quite common for the bone of the mandible and the maxilla of older individuals to have resorbed during their lifetime to the extent that in the case of the mandible it is too thin and weak to support dentures and presents a high risk of fracture.
The main problems associated with the use of powdered hydroxylapatite, tricalcium phosphate, autogenous cancellous bone, or demineralized bone for alveolar ridge augmentation are the migration of the mineral powder and the resorption of the powder.
Hydroxylapatite was then injected around the graft to fill in the defects and placed in the buttress regions as well.
www.freepatentsonline.com /4657548.html   (5701 words)

  
  English Hydroxylapatite
Hydroxylapatite, also frequently called hydroxyapatite, is a naturally occurring form of calcium apatite with the formula Ca (OH), but is usually written Ca to denote that the crystal unit cell comprises two molecules.
Hydroxylapatite is the main mineral component of dental enamel, dentin, and bone.
Hydroxylapatite can be used as a filler to replace amputated bone or as a coating to promote bone ingrowth into prosthetic implants.
articles.gourt.com /?article=hydroxyapatite   (306 words)

  
 Implant with bioactive particles stuck and method of manufacturing the same - Patent 5934287
In such an implant, the connection state between the bone and the hydroxylapatite layer is called bio-integration, and it is said that the implant and the bone are chemically coupled to each other.
In a method of coating the hydroxylapatite layer, a powder of hydroxylapatite is adhered to the surface of the implant by a plasma thermal spraying method and so on.
However, when these fine particles are hydroxylapatite (HAP) or tricalcium phosphate having high bio-activity and are formed of the material which is absorbed by bone as in the present invention, these particles have osteo-conduction to contribute the formation of bone immediately after the implantation of the complete implant and to function to help the osteo-integration.
www.freepatentsonline.com /5934287.html   (6235 words)

  
 Histological study of hydroxylapatite implants in rat zygomatic arch
Among other procedures, hydroxylapatite is presently used in the treatment of periodontal lesions, covering of metallic implants and orthognatic surgery.
Several studies have shown that hydroxylapatite is an osteoconductive material (1,2) and that more bone is usually deposited in particulate ceramic implants in comparison to block implants (3).
200, a hydroxylapatite with a porous microstructure resembling bone and a porosity size of 150 µm, considered adequate for bone ingrowth (10), was used as positive control.
www.forp.usp.br /bdj/bdj12(1)/trab02121/trab02121.html   (2582 words)

  
 Brazilian Dental Journal: Rosa et al: Hydroxylapatite and Tricalcium Phosphate Implants in the Dental Alveolus of Rats. ...
Hydroxylapatite and Tricalcium Phosphate Implants in the Dental Alveolus of Rats.
As to HA 40, it is possible that it did not reach an initial stabilization because it became a block inside the alveoli, and the growth of connective tissue may have led to exposure of the implants, with their consequent expulsion from the alveoli.
Thus, when hydroxylapatites are used with this objective it is desirable that the material act as a permanent implant; considering its high absorption rate, this seems not to occur with MIC.
www.forp.usp.br /bdj/t0562.html   (2914 words)

  
 Ceramic forming process - Patent 4312821
The green bodies comprising hydroxylapatite or a mixture of hydroxylapatite and whitlockite are sintered in accordance with the procedures described in Jarcho U.S. Pat.
As stated therein, the composition of the ultimately produced ceramic, that is, whether hydroxylapatite or a mixture of hydroxylapatite and whitlockite depends on the molar ratio of calcium to phosphorus in the gelatinous precipitate.
Hydroxylapatite in the form of a gelatinous precipitate of a phosphate of calcium having a molar ratio of calcium to phosphorus of about 1.67 prepared according to the procedures described in Jarcho U.S. Pat.
www.freepatentsonline.com /4312821.html   (4221 words)

  
 Clinique du Docteur Jean Causse   (Site not responding. Last check: 2007-11-02)
From a compatibility stand point, hydroxylapatite is the most promising implant material currently in use.
Hydroxylapatite, when in composite form with Flex (silastic) or Teflon, offers a wide range of use from surgery for chronic otitis media to pure functional surgery.
The prostheses that are in use, are made of a head of dense hydroxylapatite, a flexible metallie link of titanium, and a shaft of either Flex H/A or Teflon.
www.clinique-causse.com /pages/081.html   (2437 words)

  
 Purification and Characterization of Diacylglycerol Pyrophosphate Phosphatase from Saccharomyces cerevisiae -- Wu et ...
Hydroxylapatite peak I DGPP phosphatase activity eluted from Mono Q I at a salt concentration of 0.12 M (Fig.
Overall, the hydroxylapatite peak I DGPP phosphatase was purified 33,333-fold over the cell extract with an activity yield of 0.73% to a final specific activity of 150 µmol/min/mg (Table 1).
Hydroxylapatite peak II DGPP phosphatase was purified 24,666-fold over the cell extract to a final specific activity of 111 µmol/min/mg with an activity yield of 4% (Table 1).
www.jbc.org /cgi/content/full/271/4/1868   (7082 words)

  
 Breast Cancer Research | Full text | Estrogen receptor of primary breast cancers: evidence for intracellular proteolysis
The aims of the present study were to demonstrate that hydroxylapatite adsorption assay easily identifies cleaved cytosolic ER forms and to assess the origin of such ER forms.
H]oestradiol-binding capacities measured by hydroxylapatite assay; ABC domains are indeed required for hydroxylapatite adsorption [12].
In practice, for clinical correlation studies devoted to analysis of these hypotheses, we propose that a hydroxylapatite extraction assay should be performed as a complement to the usual immunohistochemical test (or Abbott's ER enzyme immunoassay [4]), in view of the small size of most tumours that restrict the cytosol amount.
breast-cancer-research.com /content/2/6/444   (6432 words)

  
 ASTM F1185-03 Standard Specification for Composition of Hydroxylapatite for Surgical Implants
For a material to be called hydroxylapatite, it must conform to this specification.
1.2 The biological response to hydroxylapatite in soft tissue and bone has been characterized by a history of clinical use (1-3)² and by laboratory studies (4-6).
1.4 This specification specifically excludes hydroxylapatite coatings, amorphous calcium phosphate, ceramic-glasses, tribasic calcium phosphate, whitlockite, and alpha- and beta-tricalcium phosphate.
www.astm.org /DATABASE.CART/REDLINE_PAGES/F1185.htm   (226 words)

  
 Stryker Howmedica Osteonics (Stryker Orthopaedics) - Mahway, NJ:Robotic Plasma Spraying and Ceramic Powder Manufacturing
Hydroxylapatite is a hexagonal, calcium-phosphate mineral used to promote bone growth onto orthopaedic implants.
This process involves loading the plasma gun with hydroxylapatite, and using a plasma flame to spray the partially melted powder onto the part.
Hydroxylapatite (HA) is a hexagonal, calcium-phosphate mineral used to promote bone growth onto orthopaedic implants.
www.bmpcoe.org /bestpractices/internal/sho/sho_3.html   (583 words)

  
 J9712.HTM
Hydroxylapatite as an alloplastic graft in the treatment of human periodontal osseous defects.
Augmentation of the atrophic edentulous ridge with porous replamineform hydroxyapatite (Interpore-200).
The use of a porous hydroxylapatite implant in periodontal defects, treatment of Class II furcation lesions in lower molars.
das.cs.amedd.army.mil /journal/J9712.HTM   (3880 words)

  
 Hydroxylapatite - Wikipedia, the free encyclopedia
Hydroxylapatite, also frequently called hydroxyapatite, is a mineral.
It is a naturally occurring form of calcium apatite with the formula Ca (OH), but is usually written Ca to denote that the crystal unit cell comprises two molecules.
Hydroxylapatite is the main mineral component of bone.
en.wikipedia.org /wiki/Hydroxylapatite   (299 words)

  
 Hydroxylapatite-coated hip implants. Multicenter three-year clinical and - Wheeless' Textbook of Orthopaedics
The application of a thin coating of hydroxylapatite to total hip implants has provided the opportunity to realize stable fixation of a press-fit prosthesis without a porous coating or an intervening fibrous tissue layer.
The femoral prosthesis used was a roughened titanium alloy with a 50-microns surface treatment of hydroxylapatite applied to the proximal one third.
Femoral cancellous condensation characteristically is seen at the transition zone of hydroxylapatite coated-to-uncoated stems (86%), whereas up to 32% of cases show cortical hypertrophy at the medial distal stem.
www.wheelessonline.com /ortho/hydroxylapatite_coated_hip_implants_multicenter_three_year_clinical_and   (311 words)

  
 Emanuel Horowitz
In some cases a ceramic-like material, calcium hydroxylapatite, is then plasma sprayed onto the previously deposited coating to form a composite, double-layered, interlocked and bonded structure.
The composition of calcium hydroxylapatite was determined using wet chemical analysis, infrared spectroscopy, and X-ray dispersive analysis.
X-ray diffraction and infrared spectroscopy were used to determine the microstructure of calcium hydroxylapatite which yielded quantitative data on the degree of crystallinity.
www.jhu.edu /~matsci/people/faculty/horowitz/horowitz.html   (425 words)

  
 Skin Medicine USA Radiance Treatment - Collagen alternative for facial soft tissue augmentation   (Site not responding. Last check: 2007-11-02)
Because calcium hydroxylapatite is a normal constituent of bone, it should not elicit a chronic inflammatory or immune response.
Calcium hydroxylapatite has been used in humans for a long time in prosthetic implants in dental, facial and orthopedic surgery.
While calcium hydroxylapatite has similar chemical and structural characteristics as bone and teeth and therefore is naturally compatible with the body, the Radiance material is synthetic and man-made similar to a calcium phosphate.
www.skinmedicine.com /radiance.htm   (613 words)

  
 Lifecore Hydroxylapatite (HA) Coated Implants
These threaded implants combine a high-quality hydroxylapatite (HA) coating with a popular external hex connection, making them an excellent choice for both single tooth and multiple-unit restorations.
These externally hexed cylinders employ the clinically proven design of the original press-fit HA implant with hydroxylapatite (HA) coating, while adding a 0.5mm machined collar.
Hydroxylapatite coatings have been used successfully on dental and orthopedic implants for many years.
www.lifecore.com /Products/hacoated.asp   (269 words)

  
 Abstract Archvive
Two patients were treated with surgical implantation of synthetic, granular, nonporous hydroxylapatite to correct bone defects around dental implants.
Ultrastructural examination of biopsy specimens taken several months later showed that the hydroxylapatite material was encapsulated mostly by fibrous connective tissue, without any signs of active inflammation.
These findings confirm the results of pervious studies, in which it was hypothesized that the electron-dense structures were of a mucopolysaccaride nature and might prove the close bond between the hydroxylapatite and the tissues.
www.quintpub.com /journals/archive_display_abstract.php3?journalArt=72   (140 words)

  
 Standard Specification for Composition of Hydroxylapatite for Surgical Implants - ASTM F1185-03   (Site not responding. Last check: 2007-11-02)
For a material to be called hydroxylapatite, it must conform to this specification.
1.2 The biological response to hydroxylapatite in soft tissue and bone has been characterized by a history of clinical use (1-3)² and by laboratory studies (4-6).
1.4 This specification specifically excludes hydroxylapatite coatings, amorphous calcium phosphate, ceramic-glasses, tribasic calcium phosphate, whitlockite, and alpha- and beta-tricalcium phosphate.
webstore.ansi.org /ansidocstore/product.asp?sku=ASTM+F1185-03   (199 words)

  
 SKINTOLOGY - Welcome
Radiance consists of calcium hydroxylapatite suspended in gel (carboxymethylcellulose).
Because calcium hydroxylapatite is a normal constituent of bone, it should not elicit a chronic inflammatory or immune response.
Additionally, the gel carrier does not require allergy testing, as is required with collagen.
www.skintologyny.com /spas/md-radiance.php   (63 words)

  
 Big Sky Cosmetic Surgery - Radiesse™
Radiesse consists of calcium hydroxylapatite suspended in gel (carboxymethycellulose).
Calcium hydroxylapatite has been used in humans for a long time in prosthetic implants in dental, facial, and orthopedic surgery.
The longest term studies come from Italy and suggest that Radiesse FN shows promise as a new agent for facial contouring with no serious side effects and reasonable efficacy and durability.
www.bigskycosmeticsurgery.com /non_radiesse.php   (156 words)

  
 Hydroxylapatite Powders for Implant Coatings
Dense, porous, resorbable and nonresorbable are all too familiar terms associated with hydroxylapatite (HA) bone grafting materials.
While each of the above have their clinical applicability in osseous oral rehabilitation, the HA powder characteristics that ensure optimal plasma spray coatings to implants are distinctly different.
While multiple parameters are important in plasma spraying, control of the powder is the first step toward high-quality coatings.
www.astm.org /DIGITAL_LIBRARY/STP/PAGES/STP25178S.htm   (285 words)

  
 HYDROXYLAPATITE - where to bes buy
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Hydroxylapatite is the main mineral component of bone.
I'm a Russian geologist and spent lot of time hunting meteorites, minerals, rocks and fossils all around the World.
www.squidoo.com /HYDROXYLAPATITE/?x=1&adult=false&ufg=false   (221 words)

  
 APATITE (Calcium (Fluoro-, Chloro-, Hydroxyl-) Phosphate)
These ions can freely substitute in the crystal lattice and all three are usually present in every specimen although some specimens have been close to 100% in one or the other.
The rather non-inventive names of these minerals are Fluorapatite, Chlorapatite and Hydroxylapatite.
The three are usually considered together due to the difficulty in distinguishing them in hand samples using ordinary methods.
www.galleries.com /minerals/phosphat/apatite/apatite.htm   (338 words)

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