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Topic: Hypertriglyceridemia


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  Familial Hypertriglyceridemia - Health Centers
Familial hypertriglyceridemia is a common inherited disorder in which the level of triglycerides (a type of fat) in a person's blood are higher than normal.
Familial hypertriglyceridemia is caused by a genetic defect, which is passed on in an autosomal dominant fashion.
Risk factors are a family history of hypertriglyceridemia or a family history of heart disease before the age of 50.
www.wftv.com /encyclopedia/6860082/detail.html   (513 words)

  
 Postgraduate Medicine: Does hypertriglyceridemia increase risk for CAD?
Elevated triglyceride levels are a marker for a clinical condition known as the insulin resistance syndrome, the metabolic syndrome, or syndrome X. Patients with this syndrome are at significantly increased risk for atherosclerotic disease.
The triad of hypertriglyceridemia, low HDL cholesterol levels, and elevated levels of small, dense LDL cholesterol particles is common in this syndrome and in diabetes.
Hypertriglyceridemia may predict the presence of small, dense LDL particles.
www.postgradmed.com /issues/2000/12_00/coughlan.htm   (3196 words)

  
 Triglycerides   (Site not responding. Last check: 2007-09-10)
Hypertriglyceridemia is due to increased CM or VLDL.
Hyperlipemia is mostly associated with hypertriglyceridemia with a mild increase in cholesterol.
Hypertriglyceridemia is due to increased VLDL and results in hepatic lipidosis (and liver failure with increased liver enzymes), hypoglycemia, renal disease and central nervous system signs.
www.diaglab.vet.cornell.edu /clinpath/modules/chem/hypert.htm   (461 words)

  
 Discovery Health :: Diseases & Conditions :: familial hypertriglyceridemia
Familial hypertriglyceridemia is an inherited disorder that causes high triglycerides in the blood.
A person with familial hypertriglyceridemia has an increased risk of developing pancreatitis.
This is an inflammation of the pancreas that may cause severe abdominal pain and, rarely, death.
www.health.discovery.com /encyclopedias/illnesses.html?article=28   (250 words)

  
 Case Study: A 55-Year-Old Man With Obesity, Hypertriglyceridemia, and Newly Diagnosed Type 2 Diabetes Who Collapsed and ...
Hypertriglyceridemia can be primary (associated with familial hypertriglyceridemia) or secondary (due to diabetes mellitus, hypothyroidism, kidney disease, or medication).
Hypertriglyceridemia and low HDL cholesterol (<35 mg/dl) are commonly seen in the insulin resistance syndrome, or Syndrome X. In fact, an increase in plasma triglyceride is the most common metabolic characteristic of Syndrome X. Although all insulin-resistant patients do not develop type 2 diabetes, many do.
Hypertriglyceridemia should be carefully monitored and aggressively treated by weight loss, diet, exercise, alcohol restriction, and pharmacological means to keep serum levels <400 mg/dl to prevent possible pancreatitis and <200 mg/dl to prevent coronary heart disease.
journal.diabetes.org /clinicaldiabetes/V17N41999/pg186.htm   (1211 words)

  
 Lipids Online Slides: hypertriglyceridemia, coronary heart disease
This figure does not depict the important contribution of postprandial hypertriglyceridemia, which often occurs in these same patients, wherein elevated postprandial chylomicrons (from the intestine) may also contribute to hypertriglyceridemia, the atherogenic lipid profile described above, and the creation of chylomicron remnant particles, which may be significantly atherogenic.
First of all, hypertriglyceridemia is associated with the accumulation of chylomicron remnants, which we know can be atherogenic, and accumulation of VLDL remnants, which are also atherogenic.
Hypertriglyceridemia is also associated with increased coagulability and decreased fibrinolysis, as shown by its association with increased levels of plasminogen activator inhibitor 1 (PAI-1) and factor VII and its activation of prothrombin to thrombin.
www.lipidsonline.org /slides/slide01.cfm?q=hypertriglyceridemia   (1209 words)

  
 Endocrine Today - Emerging Treatments for Coronary Heart Disease: The Role of Omega-3 Fatty Acids
Two exceptions to this rule are the hypertriglyceridemias associated with alcohol ingestion and use of oral estrogens due to simultaneous alterations in hepatic lipase: In these two conditions, high triglycerides occur in conjunction with high HDL cholesterol levels.
First, not every case of hypertriglyceridemia is associated with increased CHD risk, creating “noise” in the data when large cohorts with different types of hypertriglyceridemias are studied.
For example, mild hypertriglyceridemia in an otherwise healthy young woman on oral contraceptives is likely a benign phenomenon, whereas a similar finding in a patient with other components of the metabolic syndrome or with diabetes is likely associated with substantial cardiovascular risk.
www.endocrinetoday.com /monograph/0604/chd.asp   (2431 words)

  
 BioMed Central | Full text | Potential of essential fatty acid deficiency with extremely low fat diet in lipoprotein ...
Eruptive xanthomas, which are associated with hypertriglyceridemia, developed on the proband's buttocks at week 20 and subsequently spread to the upper arms and medial aspects of thighs as her TG levels rose.
Outcome goals were clearly set at the onset of her pregnancy care, including nutritional management of the expected rise in triglyceride levels associated with the estrogen surge of pregnancy to prevent acute pancreatitis, and avoidance of clinical EFA deficiency in both the mother and the fetus.
Pregnancy-induced hypertriglyceridemia is estimated to be the cause in 4–6% of all pancreatitis cases during pregnancy, while most cases result from cholelithiasis [4].
www.biomedcentral.com /1471-2393/4/27   (4223 words)

  
 Familial hypertriglyceridemia (Disease)... Fort Lauderdale, Florida   (Site not responding. Last check: 2007-09-10)
Familial hypertriglyceridemia is a common inherited disorder in which the concentration of very low density lipoprotein (VLDL) is elevated in the plasma.
The gene mutation for familial hypertriglyceridemia causes a mild to moderate elevation of triglycerides in the blood, though how exactly it does so is unknown.
Nicotinic acid or gemfibrozil are drugs that have effectively reduced triglycerides in people affected with familial hypertriglyceridemia.
www.browardhealth.org /16722.cfm   (426 words)

  
 Management of Dyslipidemia in Primary Care - Annotation N
The most common secondary causes of hypertriglyceridemia are alcohol, diabetes, and hypothyroidism.
Hypertriglyceridemia can be caused by or exacerbated by an underlying medical disorder.
A thorough review of the patient's chart and previous lipid panels may support the possibility of a drug side effect as the etiology for the lipid abnormality, or a trial off the suspected agent may be required for confirmation.
www.oqp.med.va.gov /cpg/DL/dl_cpg/content/annotations/annoN.htm   (406 words)

  
 eMedicine - Hypertriglyceridemia : Article by Elena Citkowitz
Hypertriglyceridemia can be categorized by the Fredrickson classification (analysis of lipids by beta-quantification—ultracentrifugation followed by electrophoresis).
Hypertriglyceridemia is correlated with an increased risk of cardiovascular disease (CVD), particularly in the setting of low HDL cholesterol (HDL-c) levels and/or elevated LDL cholesterol (LDL-c) levels.
Hypertriglyceridemia is a laboratory diagnosis; therefore, a differential diagnosis is not appropriate.
www.emedicine.com /med/topic2921.htm   (6492 words)

  
 Medical Encyclopedia: Familial hypertriglyceridemia (Print Version)
Familial hypertriglyceridemia is caused by a genetic defect, which is passed on in an autosomal dominant fashion.
This means that if you get a bady copy of the gene from just one of your parents,  you will have the condition.
If high triglyceride levels persist despite diet changes, medication may be needed.  Nicotinic acid  and gemfibrozil have been shown to effectively reduced triglycerides in those with familial hypertriglyceridemia.
www.nlm.nih.gov /medlineplus/print/ency/article/000397.htm   (431 words)

  
 Hypertriglyceridemia in the acquired immunodeficiency syndrome.
RESULTS: Mean triglyceride concentrations and the prevalence of hypertriglyceridemia (50 percent) were significantly increased in patients with AIDS compared with control subjects (p less than 0.002 and p less than 0.005, respectively), whereas the mean triglyceride levels of HIV-positive subjects were intermediate.
In patients with AIDS, mean triglyceride levels and the prevalence of hypertriglyceridemia were similar in the presence and absence of wasting.
CONCLUSION: Hypertriglyceridemia is a common finding in AIDS and is independent of the degree of wasting.
www.aegis.com /aidsline/1989/apr/M8940203.html   (482 words)

  
 Hypertriglyceridemia -- Pejic and Lee 19 (3): 310 -- The Journal of the American Board of Family Medicine
Hypertriglyceridemia is a risk factor for pancreatitis and it
Hypertriglyceridemia: new insights and new approaches to pharmacologic therapy.
Consensus statement: role of therapy with "statins" in patients with hypertriglyceridemia.
www.jabfm.org /cgi/content/full/19/3/310   (2210 words)

  
 Hypertriglyceridemia - Wikipedia, the free encyclopedia
In medicine, hypertriglyceridemia (or "Hypertriglyceridaemia") denotes high (hyper-) blood levels (-emia) of triglycerides, the most abundant fatty molecule in most organisms.
A related term is "Hyperglyceridemia" or "Hyperglyceridaemia", which refers to a high level of all glycerides, including monoglycerides, diglycerides and triglycerides.
Treatment of hypertriglyceridemia is by restriction of carbohydrates and fat in the diet, as well as with niacin, fibrates and statins (three classes of drugs).
en.wikipedia.org /wiki/Hypertriglyceridemia   (149 words)

  
 Hypertriglyceridemia - WrongDiagnosis.com
The cause of Hypertriglyceridemia may be more easily identified if other symptoms exist.
When you follow a link to our interactive multiple symptoms page, you will be able to modify your list by adding and removing symptoms thus helping to better research your condition.
This information refers to the general prevalence and incidence of these diseases, not to how likely they are to be the actual cause of Hypertriglyceridemia.
www.wrongdiagnosis.com /sym/hypertriglyceridemia.htm   (512 words)

  
 Fenofibrate Is Effective in Treating Hypertriglyceridemia Associated with HIV-related Lipodystrophy
The aim of the current study was to determine the effectiveness of fenofibrate in treating hypertriglyceridemia associated with highly active antiretroviral therapy-associated HIV lipodystrophy syndrome (HLS).
Fenofibrate is an effective, well-tolerated treatment for hypertriglyceridemia associated with HLS.
Fenofibrate is effective in treating hypertriglyceridemia associated with HIV lipodystrophy.
www.hivandhepatitis.com /recent/lipo/cholesterol/080204_b.html   (259 words)

  
 I-88: Gemfibrozil Effectively Lowers Protease-Associated Hypertriglyceridemia in HIV-Infected Patients - The Body   (Site not responding. Last check: 2007-09-10)
In addition to elevated cholesterol, HIV-infected persons may have elevated levels of triglycerides, which have been associated with increased likelihood of pancreatitis and cardiovascular risks in uninfected persons.
Hypertriglyceridemia has been associated with HIV-associated catabolism in patients with the wasting syndrome, has also been documented in patients who are asymptomatic, including those not taking PIs.
In patients with hypertriglyceridemia on PIs, gemfibrozil seems to be safe and well-tolerated, but larger studies are needed to assess long term efficacy in chronic and changing regimens and other treatments will be needed to treat the common occurance of elevated cholesterol in persons living with HIV.
www.thebody.com /confs/icaac98/i88.html   (484 words)

  
 Hypertriglyceridemia and Atherosclerosis -- Feeman 128 (1): 73 -- Annals of Internal Medicine
Hypertriglyceridemia and Atherosclerosis -- Feeman 128 (1): 73 -- Annals of Internal Medicine
Pure hypertriglyceridemia was seen in only 9% of the men and
Is hypertriglyceridemia a risk factor for atherosclerotic cardiovascular disease?
www.annals.org /cgi/content/full/128/1/73-a   (558 words)

  
 Severe and Moderate Hypertriglyceridemia Secondary to Citalopram and Fluoxetine -- Teitelbaum 41 (5): 448 -- ...   (Site not responding. Last check: 2007-09-10)
The primary care physician recommended gemfibrozil (600 mg daily) to treat hypertriglyceridemia, while fluoxetine (20 mg daily) was restarted for recurrent depression.
Suga S, Tamasawa N, Kinpara I, et al: Identification of homozygous lipoprotein lipase gene mutation in a woman with recurrent aggravation of hypertriglyceridemia induced by pregnancy.
Jeng J, Jeng C, Sheu W, et al: Gemfibrozil treatment of hypertriglyceridemia: improvement on fibrinolysis without change of insulin resistance.
psy.psychiatryonline.org /cgi/content/full/41/5/448   (617 words)

  
 Severe Hypertriglyceridemia Secondary to Venlafaxine and Fluoxetine -- Teitelbaum 42 (5): 440 -- Psychosomatics   (Site not responding. Last check: 2007-09-10)
hypertriglyceridemia apparently as a result of exposure to fluoxetine
Tozuka M, Yamauchi K, Hidaka H, et al: Characterization of hypertriglyceridemia induced by L-asparaginase therapy for acute lymphoblastic leukemia and malignant lymphoma.
Teitelbaum M: Severe and moderate hypertriglyceridemia secondary to citalopram and fluoxetine.
psy.psychiatryonline.org /cgi/content/full/42/5/440   (719 words)

  
 Hypertriglyceridemia and Atherosclerosis -- Avins 128 (1): 74 -- Annals of Internal Medicine
Hypertriglyceridemia and Atherosclerosis -- Avins 128 (1): 74 -- Annals of Internal Medicine
Is hypertriglyceridemia a risk factor for atherosclerotic disease?
The status of hypertriglyceridemia as a risk factor for coronary heart disease.
www.annals.org /cgi/content/full/128/1/74?ck=nck   (458 words)

  
 Common problems in the management of hypertriglyceridemia -- Fung and Frohlich 167 (11): 1261 -- Canadian Medical ...
A 41-year-old man presents for assessment of severe hypertriglyceridemia.
Hypertriglyceridemia may be the result of either genetic defects
levels, which are often reduced in patients with hypertriglyceridemia.
www.cmaj.ca /cgi/content/full/167/11/1261   (2411 words)

  
 Effect of Postprandial Hypertriglyceridemia and Hyperglycemia on Circulating Adhesion Molecules and Oxidative Stress ...   (Site not responding. Last check: 2007-09-10)
Effect of Postprandial Hypertriglyceridemia and Hyperglycemia on Circulating Adhesion Molecules and Oxidative Stress Generation and the Possible Role of Simvastatin Treatment -- Ceriello et al.
hypertriglyceridemia is a risk factor for CVD (2), whereas in
Kowalska I, Straczkowski M, Szelachowska M, Kinalska I, Prokop J, Bachorzewska-Gajewska H, Stepien A: Circulating E-selectin, vascular adhesion molecule-1, and intercellular adhesion molecule-1 in men with coronary artery disease assessed by angiography and disturbances of carbohydrate metabolism.
diabetes.diabetesjournals.org /cgi/content/full/53/3/701   (3797 words)

  
 Management of Hypertriglyceridemia   (Site not responding. Last check: 2007-09-10)
Patients with hypertriglyceridemia are extremely sensitive to weight loss, generally much more so than patients with hypercholesterolemia.
These patients often have post-prandial triglycerides in excess of 1000 mg/dl putting them at risk for developing pancreatitis.
iacin and gemfibrozil are the preferred agents for the treatment of hypertriglyceridemia.
www.md-phc.com /education/trig.html   (121 words)

  
 Case Study: Hypertriglyceridemia in a Woman With Insulin Resistance -- Ilag 19 (4): 183 -- Clinical Diabetes
Case Study: Hypertriglyceridemia in a Woman With Insulin Resistance -- Ilag 19 (4): 183 -- Clinical Diabetes
Case Study: Hypertriglyceridemia in a Woman With Insulin Resistance
Hypertriglyceridemia is the most common lipid abnormality in
clinical.diabetesjournals.org /cgi/content/full/19/4/183   (964 words)

  
 Insulin Therapy for a Non-Diabetic Patient with Severe Hypertriglyceridemia -- Jabbar et al. 17 (5): 458 -- Journal of ...
In this study of an adolescent patient with hypertriglyceridemia,
A 13-year-old white male was referred for evaluation of hypertriglyceridemia.
Chait A, Bruzzell JD: Severe hypertriglyceridemia: role of familial and acquired disorders.
www.jacn.org /cgi/content/full/17/5/458   (1630 words)

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