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Topic: Hyposensitization

	ALLERGY TESTING (Site not responding. Last check: 2007-10-14)
		This vaccine, actually is a hyposensitization injection, given subcutaneously (often at home) attempting to desensitize your pet to those things known to be causing a problem.
		The basic principle of desensitization (hyposensitization) is to inject small amounts of the substances known to cause the allergic signs in increasing concentrations and at regular intervals in an effort to induce a tolerance of these substances by the pet’s body.
		Hyposensitization injections and testing for food allergy is not successful and therefore not recommended.
	www.gentlepetcare.com /allergy_testing.htm (496 words)

	Oral hyposensitization in the treatment of allergies - Patent 4822611
		A method of treating allergies whereby hyposensitization to allergens to which the patient has been found to be sensitive by skin testing and history is induced by sequentially scheduled oral administration of titrated amounts of allergenic extracts in a liquid vehicle comprising defined proportions of a selected hexose monosaccharide and ethyl alcohol in water.
		According to this invention, hyposensitization to various allergens is induced by sequentially scheduled oral administrtion of titrated amounts of the allergens to which the patient has been found to be sensitive, in a liquid vehicle comprising defined proportions of a selected hexose monosaccharide and ethyl alcohol in water.
		Among the advantages of practice of allergic hyposensitization according to the present invention is that measurement of the administered doses need not be as precise as that required for subcutaneous injection.
	www.freepatentsonline.com /4822611.html (3968 words)

	Practice parameters for Allergen Immunotherapy - Immunotherapy Glossary (Site not responding. Last check: 2007-10-14)
		Other terms that have been used for allergen immunotherapy are hyposensitization, allergen-specific desensitization, and the common terms allergy shots or injections.
		Hyposensitization was formerly used interchangeably with allergen immunotherapy.
		Immunomodulation is a global term that refers to a wide range of drug or immunologic interventions that alter normal or abnormal immune responses by deletion of specific T or B cells, immune deviation, anergic induction of peripheral or central tolerance, or modification of various inflammatory pathways (eg, chemotaxis, adhesins, or intracytoplasmic signaling).
	www.jcaai.org /PP/ai_3_glossary.asp (673 words)

	ALLERGY TESTING & HYPOSENSITIZATION
		Therefore, hyposensitization represents a treatment option that should be explored, especially for a young pet or one that has a prolonged seasonal involvement.
		Although hyposensitization does not provide a cure for allergy.
		The goal of hyposensitization is to decrease this number of acute attacks to the minimum possible.
	www.vetofkaty.com /GeneralConditions/AllergyTest-Hyposensitization.htm (450 words)

	Efficacy of hyposensitization in feline allergic diseases based upon results of in vitro testing for allergen-specific ...
		A survey was undertaken to evaluate the responses to hyposensitization in cats for which a diagnosis of allergic disease was made by assessment of clinical signs and evaluation of allergen-specific immunoglobulin E (IgE) using the radioallergosorbent test (RAST).
		In nine patients, the hyposensitization was discontinued due to lack of response.
		The results suggest that confirmation of a suspected diagnosis of allergic disease in cats by means of in vitro tests and subsequent therapy with hyposensitization should be a major consideration in feline practice.
	www.jaaha.org /cgi/content/abstract/33/3/282 (294 words)

	integrityweb.com - Atopy (Inhaled Allergies) and Hyposensitization
		Hyposensitization is the administration of gradually increasing quantities of allergen extracts to a dog or cat to diminish the adverse signs associated with exposure to that allergen.
		Initially, this consists of two vials- vial 1- a start-up vial half-full and more pale in color which is used in the initial phases of small, dilute amounts when first starting hyposensitization; vial 2- maintenance vial which is a darker color when the next phase of treatment is started.
		It is recommended that hyposensitization be continued for at least one year before a response or lack of response can be evaluated.
	www.integrityweb.com /news/integritywebcom_Atopy40InhaledAllergies41andHyposensitization.htm (1136 words)

	The Physician and Sportsmedicine: Poison Ivy, Oak, and Sumac Dermatitis
		The effectiveness of hyposensitization is controversial because of the absence of well-controlled clinical studies with either oral or intramuscular use of urushiol.
		Very careful hyposensitization using oral purified urushiol has been attempted; positive results have been reported, but many annoying side effects can occur, including pruritus ani and urticaria.
		Hyposensitization with intramuscular injections has also appeared to benefit some patients.
	www.physsportsmed.com /issues/1999/05_99/garner.htm (1769 words)

	Foundation for Integrated Medicine - Childhood Migraine
		Children with frequent severe migraine were initially selected by the methods used in the study of diet and pediatric migraine at Great Ormond Street, ie freedom from headache during the oligoantigenic diet period and provocation of headache upon exposure to individual foods.
		Participation in the hyposensitization trial was offered to children who fulfilled these criteria but for whom a safe diet was unacceptably restricted.
		Forty children took part in the double-blind placebo-controlled trial of hyposensitization for migraine, each receiving an injection of placebo or active material every eight to ten weeks for a total of three injections.
	www.mdheal.org /childhoo.htm (3662 words)

	Hyposensitization Attenuates Airway Inflammation and Antigen-Induced Proliferative Response by Lymphocytes in a Rat ...
		We established a hyposensitization model of bronchial asthma in rats and examined airway responses and immunological parameters.
		Animals were hyposensitized by intraperitoneal injections of OA from day 17 to day 22.
		Hyposensitization significantly reduced the OA-induced immediate airway response, accumulation of CD4+ lymphocytes and eosinophils recovered by bronchoalveolar lavage, and the OA-induced proliferative response by blood lymphocytes.
	content.karger.com /ProdukteDB/produkte.asp?Doi=29315 (279 words)

	happypets.org - Please Spay/Neuter
		If you can minimize the non-cat allergens in the air you breathe and control the cat-oriented allergens, your body may be able to tolerate the presence of a cat.
		A physician administers a series of injections of cat allergen extract that are gradually increased in strength until the patient is able to tolerate the cat's presence with miinal if any discomfort.
		Hyposensitization isn't always successful, but it is worth a try.
	happypets.addr.com /catallergy.htm (1244 words)

	PolyCheck - Informations about hyposensitization
		Hyposensitization is the logical follow-up from an allergy test in which responsible allergens have been identified.
		Tree pollen is only found during 1-2 months, and the hyposensitization to mould fungi is controversial.
		Hyposensitization must continue for many years if not for the life of the animal because symptoms reoccur when the therapy is terminated.
	www.imovet-biocheck.com /pagesen/hyposens.htm (171 words)

	Effect of hyposensitization upon the immediate and late asthmatic reaction and upon histamine reactivity in patients ...
		Effect of hyposensitization upon the immediate and late asthmatic reaction and upon histamine reactivity in patients allergic to house dust mite (Dermatophagoides pteronyssinus) -- Van Bever and Stevens 5 (3): 318 -- European Respiratory Journal
		Effect of hyposensitization upon the immediate and late asthmatic reaction and upon histamine reactivity in patients allergic to house dust mite (Dermatophagoides pteronyssinus)
		The effect of hyposensitization (HS) upon the allergen evoked immediate asthmatic reaction (IAR), late asthmatic reaction (LAR) and upon bronchial reactivity towards histamine was examined.
	erj.ersjournals.com /cgi/content/abstract/5/3/318 (323 words)

	The Animal Medical Clinic - Allergies
		The third major form of allergy treatment is hyposensitization with specific antigen injections (or "allergy shots").
		For most dogs, a realistic goal is for the itching to be significantly reduced in severity; in some dogs, itching may completely resolve.
		Although hyposensitization is the ideal way to treat inhalant allergy, it does have some drawbacks and may not be the best choice in certain circumstances and for these reasons:
	www.theanimalmedicalclinic.com /doghealthinfo_allergies.htm (1449 words)

	References
		Enzyme potentiated hyposensitization I: The effect of pre-treatment with beta-glucuronidase, hyaluronidase and antigen on anaphylactic sensitivity of guinea pigs, rats and mice.
		Enzyme potentiated hyposensitization II: Effect of glucose, glucosamine, N-acetylamino-sugars and gelatin on the ability of beta- glucuronidase to block the anamnestic response to antigen in mice.
		Nicholson M. Kitchen I. White S. Enzyme potentiated hyposensitization III: Control by sugars and diols of the immunological effect of beta-glucuronidase in mice and patients with hay fever.
	www.drshrader.com /new_page_2.htm (435 words)

	Hyposensitization - Wikipedia, the free encyclopedia
		This can either reduce the severity or eliminate hypersensitivity altogether.
		This reaction would not cause concern, but larger reactions may require a readjustment of the treatment regimen.
		"Hyposensitization with Dermatophagoides pteronyssinus in house dust allergy: a controlled study of clinical and immunological effects.", a study from the NCBI
	en.wikipedia.org /wiki/Hyposensitization (1886 words)

	Canine Dermatology Series: Atopy
		Next to glucocorticoid treatment, immunotherapy (hyposensitization) has been found to be the most effective treatment for atopy and is effective either alone or in combination with other therapies (EFA and antihistamine treatment; discussed below) at completely circumventing the need for glucocorticoid therapy in as many as 75% of atopic cases.
		Immunotherapy (hyposensitization) is a therapeutic approach whereby an allergen is administered to a hypersensitive patient in an attempt to reduce allergic reaction when the patient is naturally exposed to the allergen in the environment.
		In any event, dogs receiving hyposensitization with specific allergens demonstrate reduced inflammatory reactions when later challenged by these same allergens, suggesting a positive effect for immunotherapy to control atopic disease.
	www.labbies.com /atopy.htm (2357 words)

	ALBAY Honeybee Venom (Apis mellifera); ALBAY Honeybee Venom Treatment Set; ALBAY Honeybee Venom Maintenance Set; ALBAY ...
		Since routine immunizations have been suspected of exacerbating auto-immune diseases, hyposensitization should be given cautiously to patients with other immunological diseases and only if the risk from insect stings is greater than the risk of exacerbating the underlying disorder.
		Doctors administering venom, whether performing initial sensitivity testing or hyposensitisation, should be experienced in both administering hyposensitisation therapy and in the treatment of severe systemic reactions.
		Hyposensitisation using ALBAY honeybee venom is recommended only for patients who demonstrate a clear history of reagin mediated allergenic reactions combined with a positive specific IgE or skin test.
	home.intekom.com /pharm/bayer/albay.html (1546 words)

	integrityweb.com - Hyposensitization Treatments
		Hyposensitization works on the same principles as "allergy shots" for humans.
		The idea is to initially expose your pet to dilute amounts of the allergen, then increase the strength in order to properly stimulate the immune system.
		Usually, hyposensitization takes 4-6 months to see signs of improvement and treatment should be continued for at least a year and often is needed for life.
	integrityweb.com /news/integritywebcom_HyposensitizationTreatments.htm (781 words)

	PetCareLibrary - Allergy Testing and Hyposensitization (pvy.com)
		The initial treatment program for those pets whose test shows a good possibility of successful therapy is initial treatment for a period of about nine months.
		If the pet has shown improvement during the first nine months then a maintenance program of injections should be continued Usually it will not be recommended to continue therapy if the initial nine month treatment does not yield significant results.
		Hyposensitization for food allergy is not highly successful and therefore not recommended.
	www.pvy.com /pcl/articles/c100010/q10000042.htm (518 words)

	Effects of oral hyposensitization with recombinant Der f2 on immediate airway constriction in a murine allergic model ...
		Effects of oral hyposensitization with recombinant Der f2 on immediate airway constriction in a murine allergic model -- Yasue et al.
		Effects of oral hyposensitization with recombinant Der f2 on immediate airway constriction in a murine allergic model
		We conclude that recombinant Der f2 exhibits both sensitizing and hyposensitizing activities in mice.
	erj.ersjournals.com /cgi/content/abstract/11/1/144 (314 words)

	Onibasu.com :: [K9Nutrition] Re: Allergy Shots (was Digest Number 5952) (Site not responding. Last check: 2007-10-14)
		Hyposensitization injections are done using tiny amounts of whatever the dog is allergic to in an attempt to accustom the body to them and stop it from reacting in an allergic manner.
		"Hyposensitization, which is the injection of very small amounts of the substance that the patient is allergic to, so that a tolerance to the substance develops.
		We send our patients to a veterinary dermatologist to determine what they are allergic to through skin testing and the dermatologist mixes up the injections based on what he finds.
	onibasu.com /archives/kn/125158.html (662 words)

	The Treatment
		The best treatment for Bo is hyposensitization therapy, which is commonly known in people as allergy shots.
		Using the results obtained from the skin testing, a special serum will be mixed containing the three allergens to which Bo is most allergic.
		Hyposensitization is a long term therapy, and it will take about 6-12 months before any improvement is seen.
	cvm.msu.edu /courses/AP/Bo/tx.htm (125 words)

	Patients with Inhalant Allergic Dermatitis
		This is not possible in many cases, but should be considered when items such as wool or feathers are identified on the intradermal skin test.
		The second form of treatment is allergy shots (hyposensitization therapy).
		The goal of hyposensitization therapy is to try and train the patient's immune system to not recognize the offending allergens as foreign and react to them.
	www.dermdvm.com /patients_with_inhalant_allergic_dermatitis.htm (505 words)

	Alternative-Doctor Home Page
		One final failure, which is not talked about: the substance with the largest reaction may NOT be the one which is causing you the most trouble, as I have found out many times with the help of Miller’s Method (see later in the testing section, page 000).
		The hyposensitization method aims to find out which substances the patient is allergic to, by giving a whole batch of prick testing, and then to administer injections of a mixture of these, increasing gradually in strength, until quite large amounts are being tolerated.
		Patients sometimes react severely and deaths due to anaphylaxis occured regularly until by common consent its use was abandoned in 1986, except in special circumstances and where full cardio-pulmonary resuscitation equipment is at hand.
	www.alternative-doctor.com /allergydotcom/testing.htm (8634 words)

	Capsules containing the active principle of an allergen, and process for their preparation - Patent 4681752 (Site not responding. Last check: 2007-10-14)
		It is the specific hyposensitization, which consists, as everybody knows, in administering to the patient increasing doses of the allergen to which he is sensitive.
		The administration of the allergen is generally carried our either parenterally or by atomization and inhalation of an aqueous solution of the allergen.
		In the capsules of the present invention, the content of the allergen active principle can vary within a wide range: generally small quantities, ranging from some thousanths to some millionths grams per dose, are enough to obtain the wanted effect.
	www.freepatentsonline.com /4681752.html (2808 words)

	Practice parameters for allergen immunotherapy - XVI. References (Site not responding. Last check: 2007-10-14)
		Bronchial sensitivity testing in asthma: an assessment of the effect of hyposensitization in house dust and pollen-sensitive asthmatic subjects.
		Modification of the late asthmatic reaction by hyposensitization in asthmatic children allergic to house dust mite (Dermatophagoides pteronyssinus) or grass pollen.
		A controlled trial of hyposensitization with adsorbed tyrosine Dermatophagoides pteronyssinus antigen in childhood asthma: in vivo aspects.
	www.jcaai.org /pp/allim_16_refs.asp (977 words)

	www.VarlAllergy.com - Products (Site not responding. Last check: 2007-10-14)
		This is the only serum allergy test that is not ELISA/RAST and double-blinded research study has shown hyposensitization based on results of Liquid Gold testing to be better than skin testing.
		To you, this will mean better success with hyposensitization … to your clients, deep satisfaction.
		To guarantee a high successful rate of hyposensitization free consultations are available to veterinarians on hyposensitization and selection of allergens to be included in the allergen immunotherapy mixture.
	www.varlallergy.com /products.html (228 words)

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