| |
| |
British Journal of Pharmacology - Specific inhibition of stretch-induced increase in L-type calcium channel currents ... |
 | | The present results suggest that cell swelling by hypotonic solution increases the L-type calcium channel currents in canine basilar artery and that herbimycin-sensitive PTK activity is primarily involved in the enhancement of calcium channel currents. |
 | | Hypotonic superfusion was employed, as it provides an alternative way to apply mechanical stress to a cell (Matsuda et al., 1996; Xu et al., 1996; 1997). |
 | | As to the effect of herbimycin A, a cytoplasmic non-receptor tyrosine kinase of 60,000 dalton, known as c-Src, is widely distributed in smooth muscle cells (Di Salvo et al., 1989) and is a common target of herbimycin A (Uehara et al., 1989; Uehara, 1997). |
| www.nature.com /bjp/journal/v130/n4/full/0703360a.html (0 words) |
|