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	IgA Nephropathy
		IgA nephropathy is a kidney disorder that occurs when IgA—a protein that helps us fight infections—settles in the kidneys.
		IgA nephropathy may run in families or be related to respiratory infections.
		Researchers sponsored by DKUHD are studying families in which IgA nephropathy is prevalent in order to understand genetic factors that may influence the disease.
	kidney.niddk.nih.gov /kudiseases/pubs/iganephropathy/index.htm (1337 words)

	eMedicine - IgA Nephropathy : Article Excerpt by: Mona Brake, MD
		IgA nephropathy (in its mildest form, also known as Berger disease) is highly variable, both clinically and pathologically.
		The association of some cases of IgA nephropathy with syndromes that affect the respiratory tract or gastrointestinal tract, such as celiac disease, led to the suggestion that IgA nephropathy is a disease of the mucosal immune system.
		Serum IgA levels are elevated in approximately half of patients with IgA nephropathy, but that increase is unlikely to play a role in the pathogenesis of the disease because markedly elevated IgA levels are observed in patients with AIDS who do not have IgA nephropathy.
	www.emedicine.com /med/byname/iga-nephropathy.htm (589 words)

	MedlinePlus Medical Encyclopedia: IgA nephropathy (Berger’s disease)
		IgA nephropathy is a kidney disorder characterized by blood in the urine.
		IgA nephropathy (Berger's disease) is a form of mesangial proliferative nephritis.
		Risk factors include having a personal or family history of IgA nephropathy or Henoch Schonlein purpura (a form of vasculitis that affects many parts of the body, and may cause a kidney lesion that is identical to the lesion of Berger's disease).
	www.nlm.nih.gov /medlineplus/ency/article/000466.htm (612 words)

	IgA Nephropathy Support Network - Shedding Light on IgA Nephropathy
		Founded in 1992, the IgA Nephropathy Support Network is a non-profit organization that serves as a clearinghouse for information on IgA Nephropathy (IgAN), a disorder of the immune system affecting the kidneys and slowly destroying them in nearly 50% of the cases.
		If your nephrologist has other patients with IgA Nephropathy, he or she may be willing to put you in contact with them, provided you are willing to sign a waiver of confidentiality that allows the doctor to do this.
		IgA Nephropathy has even been cured by homeopathy, although achieving a cure requires time and great skill on the part of the homeopathic practitioner.
	igansupport.org (1074 words)

	IgA nephropathy Information
		IgA nephropathy (also known as IgA nephritis, IgAN, Berger's disease and synpharyngitic glomerulonephritis) is a form of glomerulonephritis (inflammation of the glomeruli of the kidney).
		Primary IgA nephropathy is characterized by deposition of the IgA antibody in the glomerulus.
		IgA nephropathy has a very variable course, ranging from a benign recurrent hematuria up to a rapid progression to chronic renal failure.
	www.bookrags.com /wiki/IgA_nephropathy (2366 words)

	Nephrology - IgA Nephropathy
		IgA nephropathy or Berger's disease is a clinical/pathological entity defined by the presence of macroscopic or microscopic hematuria and mesangial IgA deposits.
		In all patients, IgA is present and is deposited mainly in the mesangium of the glomerular tuft.
		This has prompted some to suggest that IgA nephropathy and HSP are illnesses along a continuum with a common etiology.
	www.kidneydoctor.com /iga.htm (527 words)

	IGA NEPHROPATHY
		The IgA protein damages the glomeruli, leading to blood and protein in the urine, to swelling in the hands and feet, and sometimes to kidney failure.
		IgA nephropathy is a form of glomerular disease that results when immunoglobulin A (IgA) forms deposits in the glomeruli, where it creates inflammation.
		Although IgA nephropathy is found in all age groups, young people rarely display signs of kidney failure because the disease usually takes several years to progress to the stage where it causes detectable complications.
	www.websters-online-dictionary.org /definition/english/Ig/IgA+nephropathy.html (370 words)

	IgA nephropathy
		IgA nephropathy is the commonest "glomerulonephritis" (inflammation of the glomerulus) found in the developed countries of the world.
		IgA is short for immunoglobulin A, an antibody which usually helps the body to fight infections and toxins (poisons) encountered in the gut and the lungs.
		In about half of all patients the levels of IgA in the blood are raised and this, or a history of passing blood in the urine at the same time as an infection is suggestive of the diagnosis.
	renux.dmed.ed.ac.uk /EdREN/EdRenINFObits/IgALong.html (1525 words)

	IgA nephropathy (Berger's disease) - MayoClinic.com
		IgA nephropathy — also called Berger's disease — is a kidney disorder caused by abnormal deposits of the immunoglobulin A (IgA) inside the small blood vessels (glomeruli) of your kidneys.
		IgA deposits in the glomeruli hamper this process and can lead to blood and protein in your urine, high blood pressure, and swelling in your hands and feet.
		IgA nephropathy is the most common form of primary glomerulonephritis, a type of kidney disease that hinders your kidneys' ability to remove waste and excess fluids.
	www.mayoclinic.com /health/iga-nephropathy/DS00856 (330 words)

	What IgAN is (a summary)
		IgA nephropathy (or Berger's Disease, IgA nephritis) is an immune complex disorder (or immune-system mediated disease) which causes IgA immune complexes to be deposited and trapped in the glomeruli (the filters in the kidneys), where they cause inflammation (called glomerulonephritis), proliferation of cells in the mesangial matrix, and eventual scarring of the glomeruli (called glomerulosclerosis).
		IgA nephropathy is probably most accurately described as a circulating immune complex glomerulonephritis in which there is glomerular trapping of predominantly IgA immune complexes.
		This author suspects that adult who has IgA nephropathy would eventually reach end-stage renal failure if the person lived long enough (that is, didn't die of old age or other causes first).
	www.igan.ca /id45.htm (1165 words)

	IGA Nephropathy: by Ray Sahelian, M.D., health benefits
		In treating IgA nephropathy, therefore, it is necessary that suitable dose antioxidants should be supplemented to them so as to alleviate the oxidative damage in their bodies.
		Although the pathophysiology of IgA nephropathy is incompletely understood, it is likely that n-3 PUFA prevents renal disease progression by interfering with a number of effector pathways triggered by mesangial immune-complex deposition.
		Using an experimental mouse model in which early immunopathological hallmarks of IgA Nephropathy are induced by the mycotoxin vomitoxin (VT), the ameliorative effects of FO ingestion on this disease were evaluated in two studies.
	www.raysahelian.com /iganephropathy.html (2944 words)

	The International IGA Nephropathy Network
		IgA nephropathy is the commonest of a group of conditions which have the general name glomerulonephritis.
		In IgA nephropathy, like all chronic kidney problems it is important to control the blood pressure very well; you can expect that the blood pressure goal recommended for you will be lower than for many other people who have high blood pressure without kidney problems.
		The recurrence of IgA nephropathy may eventually contribute to the failure of the transplant but this is nearly always a very slow process as it is in your original kidneys.
	www.igan-world.org /infopatients.htm (2934 words)

	National Kidney Foundation: A to Z Health Guide Item
		In many parts of the world, IgA nephropathy is the most common form of glomerulonephritis--a disease that damages the tiny filtering units of the kidney, called glomeruli.
		In some patients with IgA nephropathy, this loss of kidney function progresses to chronic kidney failure, which requires dialysis treatment or a kidney transplant.
		IgA Nephropathy is sometimes called "Berger's Disease," because a French physician named Berger was one of the first to describe the disease.
	www.kidney.org /atoz/atozItem.cfm?id=76 (844 words)

	The Foundation for IgA Nephropathy
		It is a very active, friendly and positive group, and we invite everyone with an interest in IgA nephropathy and chronic renal failure to participate.
		The IgA Nephropathy Support Group is a peer support group, currently operated on Yahoo Groups.
		It is impossible to provide useful support without at least some discussion of medical issues, potential treatments, etc. The Foundation for IgA Nephropathy does not under any circumstances advise making medical decisions about treatment without consulting with your own doctors (this includes medications, diet, exercise, supplements, and all aspects of having kidney disease).
	www.igan.ca (481 words)

	Update - IgA nephropathy and CD89
		Kidney biopsies typically show deposition of IgA in the mesangium of the glomerulus and the proliferation of mesangial cells and increased amounts of mesangial matrix.
		This is a receptor for the Fc portion of IgA antibodies.
		A group from the famous Necker hospital in Paris now report in the Journal of Experimental Medicine, that in patients with IgA nephropathy there are high levels of soluble CD89 bound to IgA which circulate in the blood as a complex.
	www.learndoctor.com /updates/iganephropathy.htm (292 words)

	Loyola Univ. Health Sys. - Urology - Immunoglobulin A (IgA) Nephropathy (Site not responding. Last check: )
		It is unknown what causes IgA deposits in the glomeruli, however, in more than half of families, IgA nephropathy is inherited by an autosomal dominant gene.
		IgA nephropathy is a very heterogeneous condition, which means that the presentation varies greatly between individuals and families.
		IgA nephropathy is a silent disease that may go undetected for years, but usually onsets before the age of 40.
	www.luhs.org /health/topics/urology/iganeph.htm (462 words)

	UK NKF - Kidney Disease
		IgA is short for Immunoglobulin A, one of the types of antibody our body produces to fight infection.
		IgA is produced by glands around the throat and bowel to fight off infection.
		However, if you have had IgA nephropathy confined to the kidneys for some time, it would be very unusual for this to convert to the more serious Henoch-Schonlein purpura.
	www.kidney.org.uk /Medical-Info/kidney-disease/Iga.html (764 words)

	eMedicine - IgA Nephropathy : Article by Mona Brake, MD
		However, IgA nephropathy and gluten hypersensitivity are associated, and withdrawal of gluten from the diet of these patients has resulted in clinical and immunological improvement of the renal disease.
		IgA nephropathy has been reported in patients with HIV infection, both whites and fls, despite the rarity of typical IgA nephropathy in the fl population.
		IgA is deposited in a diffuse granular pattern in the mesangium and occasionally in the capillary wall (see Image 3).
	www.emedicine.com /med/topic886.htm (4269 words)

	eMedicine - IgA Nephropathy : Article by Mohammad Ilyas, MD, FAAP (Site not responding. Last check: )
		Despite the demonstration of a specific IgA receptor on mesangial cells and in the glomerulus of patients with IgA nephropathy, studies of the expression of Fc alpha R on peripheral blood mononuclear cells and granulocytes led to conflicting results.
		IgA nephropathy may be linked to the expression of an IgA nephropathy–specific variant of Fc alpha R receptor on monocytes.
		Although IgA nephropathy was thought to carry a relatively benign prognosis, an estimated 1-2% of all patients with IgA nephropathy develop end-stage renal failure each year from the time of diagnosis.
	www.emedicine.com /ped/topic228.htm (4311 words)

	IgA Nephropathy - Causes, Symptoms & Treatment
		IgA nephropathy is a kidney disorder caused by deposits of the protein immunoglobulin A (IgA) inside the glomeruli (filters) within the kidney.
		The IgA protein prevents this filtering process, leading to blood and protein in the urine and swelling in the hands and feet.
		The IgA protein is a normal part of the body's system to protect against disease (the immune system).
	www.healthnewsflash.com /conditions/iga_nephropathy.php (294 words)

	IgA Nephropathy
		Mesangial IgA in IgA nephropathy arises from the mucosa.
		Layward L, Allen AC, Hattersley JM, Harper SJ, Feehally J. Elevation of IgA in IgA nephropathy is localized in the serum and not saliva and is restricted to the IgA1 subclass.
		IgA nephritis: on the importance of morphological and clinical parameters in the long-term prognosis of 239 patients.
	www.medical-journals.com /real2a.htm (5752 words)

	UNC Kidney Center: IgA Nephropathy
		However in IgA nephropathy, this IgA protein is abnormally affecting the kidney even in the absence of a known kidney infection.
		Though your tonsils have been reported to be a “factory” for making IgA protein complexes, tonsillectomy has not been found to be effective and is not usually recommended (unless you suffer from frequent bouts of tonsillitis).
		Unfortunately, there is no cure for IgA nephropathy though many patients will have periods of remission when their disease is not thought to be active.
	www.unckidneycenter.org /patients/iga_nephropathy.htm (963 words)

	[No title] (Site not responding. Last check: )
		It seems that IgA anti-gliadin antibodies are elevated in patients with IgA nephropathy, but their antiendomysial & antireticulin antibodies counter the suggestion that this disease is associated with celiac disease.
		The other side of the argument is that because IgA nephropathy has been clearly demonstrated to have no visible relationship with celiac disease, and one study they cite was a trial of gluten-free diet on IgA nephropathy, which had little effect on the course of the nephropathy.
		For now, it is clear that she was referring to the gluten-free diet, and this is a whole spectrum of possible gluten-intolerance that needs some investigation.
	www.gluten-free.org /hoggan/igan.txt (280 words)

	IgA Nephropathy Resources : IGAN Biosciences
		Nair R, Walker PD. Is IgA nephropathy the commonest primary glomerulopathy among young adults in the USA?
		Julian BA, Novak J. IgA nephropathy: an update.
		ASM Press, Washington D.C. Tomana M, Novak J, Julian BA, Matousovic K, Konecny K, Mestecky J. Circulating immune complexes in IgA nephropathy consist of IgA1 with galactose-deficient hinge region and antiglycan antibodies.
	www.iganbio.com /iga_nephropathy_resources.html (139 words)

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