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Topic: Imipramine

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	Imipramine, Serum
		Imipramine is the most thoroughly studied tricyclic antidepressant for the treatment of agoraphobia and panic disorder.
		Imipramine is a tertiary tricyclic antidepressant prescribed for the treatment of various depressive disorders.
		Imipramine is metabolized to desipramine which is pharmacologically active and which is marketed separately.
	www.labcorp.com /datasets/labcorp/html/chapter/mono/td011600.htm (558 words)

	Imipramine (Tofranil) Anti-Depressant
		Imipramine was approved by the FDA for use for depression in 1959 and for enuresis in 1973.
		Because imipramine is metabolized to a secondary amine (desipramine), however, classification according to neurotransmitter type does not further elucidate imipramine's action.
		Imipramine also blocks acetylcholine receptors, and this may be responsible for its efficacy in the treatment of enuresis.
	www.rockford.uic.edu /jc/imiprami.htm (461 words)

	Imipramine -- Facts, Info, and Encyclopedia article (Site not responding. Last check: 2007-10-22)
		Imipramine is the first antidepressant to be developed in the late (The decade from 1950 to 1959) 1950s.
		Imipramine, a tertiery (A compound derived from ammonia by replacing hydrogen atoms by univalent hydrocarbon radicals) amine, inhibits the reuptake of (A neurotransmitter involved in e.g.
		Imipramine is converted to (Click link for more info and facts about desipramine) desipramine, another (Click link for more info and facts about TCA) TCA, in the body.
	www.absoluteastronomy.com /encyclopedia/i/im/imipramine.htm (187 words)

	imipramine Drug Information
		Imipramine is used to treat symptoms of depression.
		While you are taking imipramine, you will need to be monitored for worsening symptoms of depression and/or suicidal thoughts during the first weeks of treatment, or whenever your dose is changed.
		Symptoms of an imipramine overdose may include uneven heartbeats, extreme drowsiness, agitation, vomiting, blurred vision, sweating, muscle stiffness, swelling, shortness of breath, blue lips or fingernails, feeling light-headed, fainting, seizure (convulsions), or coma.
	www.drugs.com /mtm/imipramine.html (1773 words)

	Imipramine for bed-wetting
		Imipramine usually is given for 3 to 4 months and then tapered off over 3 to 4 weeks until it is stopped altogether.
		Imipramine should not be used to treat children younger than 6 years of age.
		Imipramine has not been shown to be helpful in stopping bed-wetting in older teens or children who have small bladders.
	www.webmd.com /hw/raising_a_family/hw211404.asp (457 words)

	imipramine
		The antidepressant imipramine is a dibenzazepine tricyclic antidepressant.
		A's imipramine blood level was 170 ng/ml (therapeutic range l~0-300 ng/ml), and she experienced a dramatic alleviation of her depression.
		The correlations between initiation of imipramine treatment and the onset of yawning, as well as between the reduction of yawning with dosage decrease, suggest that irnipramine was the cause of yawning.
	www.baillement.com /imipramine.html (1124 words)

	Antidepressant Medications Anti-depressant Drugs Antidepressant: imipramine, Tofranil
		Imipramine is a tricyclic antidepressant with general pharmacological properties similar to those of structurally related tricyclic antidepressant drugs such as amitriptyline and doxepin.
		Imipramine may also be useful as temporary adjunctive therapy in reducing enuresis in children aged 5 years and older, after possible organic causes have been excluded by appropriate tests.
		Imipramine should not be given in conjunction with, or within 14 days of treatment with a MAO inhibitor.
	support4hope.com /medications/antidepressants/imipramine_tofranil.htm (563 words)

	Imipramine for bed-wetting - [Medication]
		Imipramine usually is given for 3 to 4 months and then tapered off over 3 to 4 weeks until it is stopped altogether.
		Imipramine should not be used to treat children younger than 6 years of age.
		Imipramine has not been shown to be helpful in stopping bed-wetting in older teens or children who have small bladders.
	www.peacehealth.org /kbase/topic/detail/drug/hw211404/detail.htm (438 words)

	Imipramine (Tofranil®)
		Imipramine is a prescription drug and can only be obtained from a veterinarian or by prescription from a veterinarian.
		Imipramine should not be used in animals with known hypersensitivity or allergy to the drug.
		Imipramine is not commonly used in animals, and perhaps for this reason, reports of adverse and toxic effects are scant.
	www.petplace.com /drug-library/imipramine-tofranil/page1.aspx (698 words)

	imipramine - Drug Finder - MSN Health & Fitness (Site not responding. Last check: 2007-10-22)
		While you are taking imipramine you may need to be monitored for worsening symptoms of depression and/or suicidal thoughts at the start of therapy or when doses are changed.
		Imipramine may be taken several times a day or in one daily dose (usually at bedtime).
		Imipramine may increase the effects of other drugs that cause drowsiness, including other antidepressants, alcohol, antihistamines, sedatives (used to treat insomnia), pain relievers, anxiety medicines, and muscle relaxants.
	health.msn.com /drugfinder/articlepage.aspx?cp-documentid=100059747 (1490 words)

	Howstuffworks "Imipramine: A Profile of an Antidepressant Drug"
		Imipramine is used to relieve the symptoms of mental depression.
		Imipramine is also used to treat enuresis (bed-wetting) in children 6 to 12 years of age.
		Imipramine can be taken with water or with food to lessen the chance of stomach irritation, unless your doctor directs you to do otherwise.
	health.howstuffworks.com /define-imipramine.htm (1099 words)

	Imipramine
		Imipramine may be taken with or without food.
		It is especially important to check with your doctor before combining Imipramine with albuterol, antidepressants that act on serotonin, barbiturates, blood pressure medications, carbamazepine, cimetidine, decongestants, drugs that control spasms, epinephrine, flecainide, major tranquilizers, methylphenidate, norepinephrine, other antidepressants, phenytoin, propafenone, quinidine, thyroid medications, or tranquilizers and sleep aids.
		Extreme drowsiness and other potentially serious effects can result if Imipramine is combined with alcohol or other mental depressants, such as narcotic painkillers, sleeping medications, or tranquilizers.
	www.health-net.info /imipramine.html (345 words)

	Column - Imipramine, Mirtazapine, and Nefazodone: Multiple Targets
		At low concentrations, imipramine increases blood pressure by increasing the ionotrophic effect of norepinephrine on the myocardium and its vasoconstrictive effect on peripheral arterioles via its blockade of the norepinephrine uptake pump.
		Imipramine, mirtazapine, and nefazodone are at the opposite end of the spectrum from the SSRIs (e.g., sertraline) or the NSRIs (e.g., desipramine or reboxetine) in terms of number of mechanisms of action that are affected at concentrations achieved in the usual patient taking these drugs at their respective antidepressant doses.
		In contrast, the pharmacology of imipramine, mirtazapine, and nefazodone is richer or more varied or more complicated (i.e., pick the spin you prefer) than that of the SSRIs as a result of their effects on multiple mechanisms of action.
	www.preskorn.com /columns/0003.html (3864 words)

	imipramine - Depression symptoms, causes, and treatments including clinical and manic depression.
		Imipramine also is used for childhood enuresis (bedwetting), several disorders associated with chronic pain, and attention-deficit hyperactivity disorder (ADHD.
		Imipramine was first synthesized in the late 1940s and was approved by the FDA for depression in 1959 and for enuresis in 1973.
		Imipramine and other TCAs should not be used with monoamine oxidase inhibiting drugs, for example, isocarboxazid (Marplan), phenelzine (Nardil), tranylcypromine (Parnate), and procarbazine (Matulane), since high fever, convulsions and even death can occur.
	www.medicinenet.com /imipramine/article.htm (695 words)

	Imipramine for urinary incontinence
		Imipramine is a tricyclic antidepressant, but it has anticholinergic side effects that relax the smooth muscle of the bladder.
		Use of imipramine for the treatment of urinary incontinence is an unlabeled use of the medication.
		Imipramine is not a highly effective treatment for urinary incontinence, but it may be worth trying if other medications don't work or cannot be tolerated.
	www.webmd.com /hw/health_guide_atoz/hw219618.asp (511 words)

	Imipramine (PIM 273)
		Every patient with a history of significant imipramine ingestion or having symptoms, signs or ECG changes consistent with imipramine poisoning, should be admitted to an intensive care department, with immediate monitoring (for 24 hours) of ventilation and circulation, independent of the clinical condition of the patient.
		Imipramine is metabolised almost exclusively in the liver, undergoing oxidation by microsomal enzymes, followed by conjugation with glucuronic acid.
		Imipramine is mainly metabolised by demethylation to an active metabolite desipramine, and to a lesser extent by aromatic 2- hydroxylation to 2-hydroxyimipramine.
	www.intox.org /databank/documents/pharm/imiprami/imiprami.htm (4305 words)

	Parkinsn's List Drug DataBase imipramine / Tofranil
		Description: Imipramine is an antidepressant drug of the dibenzazepine type, referred to as a tricyclic because of its chemical structure.
		Imipramine and nortriptyline are known to prolong the QRS interval.
		This particularly occurs with the tertiary amine tricyclic antidepressants: amitriptyline, imipramine, clomipramine, trimipramine, and doxepin.
	www.parkinsons-information-exchange-network-online.com /drugdb/069.html (3405 words)

	Imipramine - Patient UK
		Imipramine is used to treat depression, especially when the patient is experiencing difficulty sleeping and a loss of appetite.
		Imipramine may take several weeks before you begin to feel the benefits of this treatment.
		Imipramine can cause some people to become more sensitive to sunlight than they usually are.
	www.patient.co.uk /showdoc/30002904 (976 words)

	Mechanism of Block of hEag1 K+ Channels by Imipramine and Astemizole -- García-Ferreiro et al. 124 (4): 301 -- ...
		Deactivation was slowed in the presence of imipramine (Fig.
		Deactivation kinetics in the presence of imipramine and astemizole.
		Symbols and associated error bars in B and D represent mean ± SEM for three (0.1, 2, 5, and 50 µM) and five (0.5 and 5 µM) cells for imipramine, and six (0.1, 1, and 5 µM) and nine (0.025 and 0.25 µM) cells for astemizole.
	www.jgp.org /cgi/content/full/124/4/301 (7924 words)

	National MS Society \| Tofranil (Imipramine) (Site not responding. Last check: 2007-10-22)
		Imipramine is a tricyclic antidepressant used to treat mental depression.
		Imipramine is also prescribed occasionally for the management of neurologic pain in MS.
		Imipramine may cause your skin to be more sensitive to sunlight than it is normally.
	www.nationalmssociety.org /Meds-Imipramine.asp (483 words)

	Imipramine Information on Healthline
		Imipramine is used to relieve symptoms of depression such as feelings of sadness, worthlessness, or guilt; loss of interest in daily activities; changes in appetite; tiredness; sleeping too much; insomnia; and thoughts of death or suicide.
		Do not take imipramine if you have taken a monoamine oxidase inhibitor such as isocarboxazid (Marplan), phenelzine (Nardil), or tranylcypromine (Parnate) within the last 14 days.
		If you are over 60 years of age, you may be more likely to experience side effects such as drowsiness, dizziness, unsteadiness, feeling uncoordinated, and low blood pressure.
	www.healthline.com /multumcontent/imipramine (955 words)

	Imipramine
		The IC patients were treated with imipramine hydrochloride, and the efficacy of treatment was assessed to be no change, fair, or good.
		Imipramine and amitriptyline should be used cautiously in patients who are poor metabolizers of C219.
		The plasma concentration of imipramine may increase when the drug is given concomitantly with hepatic enzyme inhibitors (e.g., cimetidine, fluoxetine) and decrease by concomitant administration of hepatic enzyme inducers (e.g., barbiturates, phenytoin), and adjustment of the dosage of imipramine may therefore be necessary.
	www.mongabay.com /health/medications/Imipramine.html (1982 words)

	Pharmacy online. elidel (Site not responding. Last check: 2007-10-22)
		Imipramine may cause dry elidel and blurred vision.
		Imipramine may make your skin more sensitive to the sun.
		If you are a diabetic, check your blood sugar more often elidel usual, especially during elidel first few weeks of imipramine elidel Call your prescriber or health elidel professional for advice if you notice a change in the results elidel blood or urine glucose tests.
	elidel.pills-onweb.com (621 words)

	Imipramine for bedwetting - [Medication]
		The exact way imipramine works to reduce bedwetting is not known.
		When treated with imipramine, about 50% of children are able to control bedwetting, at least for a short time.
		Imipramine has not been shown to be helpful in stopping bedwetting in older teens or children who have small bladders.
	www.bchealthguide.org /kbase/topic/detail/drug/hw211404/detail.htm (447 words)

	Complete Imipramine information from Drugs.com
		Imipramine may be taken with or without food.
		Use Imipramine with caution in the ELDERLY (especially those with cardiac disease) because they may be more sensitive to its effects.
		Imipramine is to be used only by the patient for whom it is prescribed.
	www.drugs.com /cdi/Imipramine_Tablets.html (1564 words)

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