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Topic: Immune thrombocytopenic purpura

Related Topics

Thrombocytopenia

Platelet

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HELLP syndrome

Clot

Leukemia

Bleeding diathesis

Autoimmune disorder

Blood

Coagulation

	Immune thrombocytopenic purpura definition - Medical Dictionary definitions of popular medical terms
		Immune thrombocytopenic purpura: A blood disorder characterized by the destruction of blood platelets due to the presence of antiplatelet autoantibodies.
		Purpura pertains to the visible hallmarks: purplish areas in the skin and mucous membranes (such as the mouth lining) where bleeding has occurred as a result of decreased platelets.
		Immune thrombocytopenic purpura (ITP) can be triggered by drugs, or associated with infection, pregnancy, or immune disorders such as systemic lupus erythematosus.
	www.medterms.com /script/main/art.asp?articlekey=24151 (422 words)

	Immune Thrombocytopenic Purpura (ITP) (Site not responding. Last check: 2007-09-21)
		Immune Thrombocytopenic Purpura (ITP) is a disorder of the blood.
		Purpura refers to the purplish- looking areas of the skin and mucous membranes (such as the lining of the mouth) where bleeding has occurred as a result of decreased platelet.
		The treatment of idiopathic thrombocytopenic purpura is determined by the severity of the symptoms.
	www.niddk.nih.gov /health/hematol/pubs/itp/itp.htm (685 words)

	What Is Idiopathic Thrombocytopenic Purpura?
		Idiopathic thrombocytopenic purpura (ITP) is a bleeding disorder in which the blood does not clot as it should.
		Thrombocytopenic (throm-bo-cy-toe-PEE-nick) means there is a lower-than-normal number of platelets in the blood.
		Chronic ITP is a long-lasting (6 months or longer) type of ITP that mostly affects adults.
	www.nhlbi.nih.gov /health/dci/Diseases/Itp/ITP_WhatIs.html (464 words)

	Immune Thrombocytopenic Purpura
		“Purpura” is a purplish looking areas of the skin and mucous membranes, such as the lining of the mouth, where bleeding has occurred as a result of decreased platelets.
		Acute, or temporary, thrombocytopenic purpura is the most common in young children.
		Thrombocytopenic purpura is considered chronic when it has lasted more than six months.
	steelseraphim.tripod.com /itp.htm (646 words)

	ITP (idiopathic thrombocytopenic purpura, immune thrombocytopenic purpura) : What is ITP? (Site not responding. Last check: 2007-09-21)
		In a nutshell, ITP (an abbreviation for "idiopathic thrombocytopenic purpura") is a disease that kills platelets.
		ITP triggers the immune system to mark platelets as foreign, and subsequently to destroy them in the spleen or, sometimes in the liver.
		ITP is generally not fatal; however, extreme cases may be life-threatening because of a risk of spontaneous hemorrhages, internal bleedings and hard-to-stop bleedings that might be caused by injuries.
	www.mediprimer.com /Hematology/itp (243 words)

	Novel Drug Boosts Platelet Production, Reversing Chronic Immune Thrombocytopenic Purpura (ITP)
		In ITP, immune system antibodies mysteriously begin to attack and destroy blood platelet cells.
		Up till now, ITP patients have typically turned to powerful drugs such as corticosteroids or intravenous immune globulin, which work by inhibiting platelet destruction.
		For some ITP patients splenectomy (surgical removal of the spleen) is another treatment option.
	news.med.cornell.edu /wcmc/wcmc_2006/11_14c_06.shtml (897 words)

	University of Miami School of Medicine - Glossary - Immune thrombocytopenic purpura
		Immune thrombocytopenic purpura: A blood disorder characterized by the destruction of blood platelets due to the presence of antiplatelet autoantibodies.
		Purpura pertains to the visible hallmarks: purplish areas in the skin and mucous membranes (such as the mouth lining) where bleeding has occurred as a result of decreased platelets.
		Immune thrombocytopenic purpura (ITP) can be triggered by drugs, or associated with infection, pregnancy, or immune disorders such as systemic lupus erythematosus.
	www.med.miami.edu /glossary/art.asp?articlekey=24151 (392 words)

	Summary of Immune Thrombocytopenic Purpura
		ITP is a bleeding disorder that can lead to bruising and bleeding that is hard to stop.
		ITP is caused by a low number of platelets in the blood.
		ITP is not the only cause of low platelets (thrombocytopenia), so diagnosis includes ruling out other possible causes of low platelets.
	www.patientlinx.com /bloodDisorders/sumitp.cfm (284 words)

	Immune Thrombocytopenic Purpura
		Immune indicates that the illness is caused by the immune system, which makes cells and antibodies that attack the person's own platelets —; the parts of the blood that help the blood to clot.
		Purpura means that the illness produces a red or purple rash that is caused by bleeding under the skin.
		ITP does not cause symptoms as long as your platelet count remains above 50,000, which usually is the minimum needed to prevent abnormal bleeding.
	www.dental.am /more.php?id=2611_0_10_0_M138 (1409 words)

	Low Platelets
		Distinguishing ITP from other conditions is usually done clinically, paying careful attention to the onset of symptoms, family history, medication use, and recent illnesses.
		This means that her immune system can attack the platelets of the growing fetus, and the baby will be extremely thrombocytopenic immediately after birth.
		Schonlein-Henoch Purpura is a condition characterized by purpura, lesions, edema, itching, and bleeding.
	www.itppeople.com /lowplate.htm (2226 words)

	Immune Thrombocytopenic Purpura
		Another type of immune mediated disorder is immune thrombocytopenic purpura (ITP), a bleeding disorder that often causes purple bruises on the skin but also may cause life threatening bleeding, e.g.
		Thrombocytopenic indicates that the illness is related to low levels of thrombocytes, also called platelets, which are cells in our blood that help stop bleeding, resulting from the attack of the immune system.
		Another form of immune mediated disorders is immune thrombocytopenic purpura (ITP), a bleeding disorder that often causes purple bruises on the skin.
	www.zlbbehring.ca /zb/n10783860/PFDiseaseCatProd10.htm (459 words)

	Idiopathic Thrombocytopenia Purpura - Lucile Packard Children's Hospital
		ITP is a blood disorder characterized by an abnormal decrease in the number of platelets in the blood.
		ITP affects approximately four to eight per 100,000 children under the age of 15 each year in the US.
		ITP platelets usually survive only a few hours, in comparison to normal platelets which have a lifespan of 7 to 10 days.
	www.lpch.org /DiseaseHealthInfo/HealthLibrary/hematology/bledidio.html (1312 words)

	AMG 531 increases platelets in patients with immune thrombocytopenic purpura
		AMG 531 increases platelets in patients with immune thrombocytopenic purpura
		Immune thrombocytopenic purpura is characterized by an immune system malfunction that recognizes the body's own platelets as foreign and destroys them, potentially resulting in dangerously low platelet counts (less than 30,000 platelets per microliter).
		For ITP patients who do not respond to these therapies, there are no effective treatment options," said James George, at the University of Oklahoma Health Sciences Center, Oklahoma City.
	www.xagena.com /news/hematologynews_net_news/f4a331b7a22d1b237565d8813a34d8ac.html (608 words)

	IMMUNE (IDIOPATHIC) THROMBOCYTOPENIC PURPURA : Contact a Family - for families with disabled children: information on ...
		ITP is thus a type of auto (self) immune disorder.
		The risk of serious bleeding in childhood ITP is very small, and usually no treatment is necessary other than avoidance of Aspirin or Ibuprofen, which increase the risk of bleeding.
		This is usually achieved by either a short course of steroid drugs (by mouth or, occasionally, by intravenous drip) which suppress the immune system, or an intravenous injection of large amounts of human, soluble antibody protein from blood donors (intravenous immunoglobulin) which interfere with the destruction of platelets by the immune system.
	www.cafamily.org.uk /Direct/i12.html (679 words)

	AllRefer Health - Idiopathic Thrombocytopenic Purpura (ITP) (Immune Thrombocytopenic Purpura, ITP)
		Idiopathic thrombocytopenic purpura is a bleeding disorder characterized by too few platelets in the blood.
		The disease occurs when immune system cells, called lymphocytes, produce antibodies against platelets.
		ITP affects women more frequently than men, and is more common in children than adults.
	health.allrefer.com /health/idiopathic-thrombocytopenic-purpura-itp-info.html (385 words)

	eMedicine - Immune Thrombocytopenic Purpura : Article by S Gerald Sandler, MD, FACP, FCAP (Site not responding. Last check: 2007-09-21)
		Background: Immune thrombocytopenic purpura (ITP) is a clinical syndrome in which a decreased number of circulating platelets (thrombocytopenia) manifests as a bleeding tendency, easy bruising (purpura), or extravasation of blood from capillaries into skin and mucous membranes (petechiae).
		In adults, thrombocytopenic purpura may be a manifestation of systemic lupus erythematosus or acute or chronic leukemia.
		Immune destruction of immunoglobulin-coated platelets is mediated by macrophage immunoglobulin G Fc (Fc gamma RI, Fc gamma RII, and Fc gamma RIII) and complement receptors (CR1, CR3).
	www.emedicine.com /MED/topic1151.htm (6259 words)

	eMedicine - Idiopathic Thrombocytopenic Purpura : Article by Michael A Silverman, MD (Site not responding. Last check: 2007-09-21)
		Background: Idiopathic thrombocytopenic purpura (ITP), also known as primary immune thrombocytopenic purpura and autoimmune thrombocytopenic purpura, is defined as isolated thrombocytopenia with normal bone marrow and the absence of other causes of thrombocytopenia.
		ITP is a decrease in the number of circulating platelets in the absence of toxic exposure or a disease associated with a low platelet count.
		Nonpalpable spleen: The prevalence of palpable spleen in patients with ITP is approximately the same as that in the non-ITP population (ie, 3% in adults, 12% in children).
	www.emedicine.com /emerg/topic282.htm (2879 words)

	Treatment with liposome-encapsulated clodronate as a new strategic approach in the management of immune ... (Site not responding. Last check: 2007-09-21)
		Immune thrombocytopenic purpura (ITP) is an autoimmune disease related to the presence of elevated levels of platelet-associated
		of macrophage Fc receptors in the uptake of platelets in ITP
		Exacerbation of autoantibody-mediated thrombocytopenic purpura by infection with mouse viruses
	www.bloodjournal.org /cgi/content/full/96/8/2834 (5033 words)

	ITP Foundation: Facts About Immune Thrombocytopenic Purpura (Site not responding. Last check: 2007-09-21)
		Purpura refers to the purplish-looking areas of the skin and mucous membranes (such as the lining of the mouth) where bleeding has occurred as a result of decreased platelet.
		We urge patients with ITP and their parents to review this material and then to consult with a licensed health professional for evaluation of treatment options suitable for them, as well as for diagnosis and answers to their personal medical questions.
		Terms And Conditions Of Use.This website, graphics, logos and photos are the property of ITP Foundation and may not be duplicated for any purpose without the permission of the owner.
	www.itpfoundation.org /itp/facts (795 words)

	NEJM -- Immune Thrombocytopenic Purpura
		--> Immune thrombocytopenic purpura is an autoimmune disorder characterized
		purpura is classified as primary or as secondary to an underlying
		Panitsas, F. P., Theodoropoulou, M., Kouraklis, A., Karakantza, M., Theodorou, G. L., Zoumbos, N. C., Maniatis, A., Mouzaki, A. Adult chronic idiopathic thrombocytopenic purpura (ITP) is the manifestation of a type-1 polarized immune response.
	content.nejm.org /cgi/content/short/346/13/995 (580 words)

	MyThyroid.com: Disease Associations
		ITP (Idiopathic thrombocytopenic purpura) is a disorder of blood platelets, a circulating fragment of blood cells responsible for ensuring that our blood coagulation system responds appropriately to blood vessel injury by helping blood clots form.
		Patients with ITP often have circulating antibodies directed against their platelets, in a manner analogous to patients with Graves' disease (GD) that have antibodies directed against their thyroid gland.
		There does not seem to be a consistent relationship between progression of ITP and treatment of GD Variable presentation of thrombocytopenia in Graves' disease.
	www.mythyroid.com /diseaseassociations.html (2196 words)

	Current topic: Idiopathic thrombocytopenic purpura -- Bolton-Maggs 83 (3): 220 -- Archives of Disease in Childhood
		Intravenous immunoglobulin versus oral corticosteroids in acute immune thrombocytopenic purpura in childhood.
		Treatment of childhood acute immune thrombocytopenic purpura with anti-D immune globulin or pooled immune globulin.
		In-labelled platelets and the efficiency of splenectomy in children and adults with idiopathic thrombocytopenic purpura: a study of 578 patients with 268 splenectomies.
	adc.bmjjournals.com /cgi/content/full/83/3/220 (2057 words)

	ITP Foundation: Immune Thrombocytopenic Purpura (ITP) in Children and Teens
		The ITP Foundation is making great efforts to raise awareness and to increase the amount of research into Immune Thrombocytopenic Purpura ("ITP"), but we need your support.
		The ITP Foundation is a tax exempt organization pursuant to Section 501(c)(3) of the Internal Revenue Code of 1986, as amended, and all donations are tax deductible as allowed by law.
		ITP Foundation announces unique collaboration with Ironman North America.
	www.itpfoundation.org (371 words)

	Immune thrombocytopenic purpura (Site not responding. Last check: 2007-09-21)
		Because more is being learned about the autoimmune nature of the disease, it is sometimes called immune thrombocytopenic purpura.
		ITP affects women more frequently than men, and is more common in children than adults.
		People with ITP should avoid taking aspirin, ibuprofen, and warfarin because these drugs interfere with platelet function and blood clotting, and bleeding may occur.
	www.dental.am /more.php?id=13439_0_14_0_M226 (452 words)

	Aortic dissection in a young man with immune thrombocytopenic purpura.
		He did, however, suffer from untreated, chronic immune thrombocytopenic purpura (ITP) and had a platelet count less than 20,000/mm(3) on admission.
		We postulate that the thrombocytopenia led to spontaneous hemorrhage within the vasa vasorum of the aorta and the subsequent development of aortic dissection.
		Chronic ITP has been associated with an increased risk of intracranial hemorrhage but, to our knowledge, has not been reported to be associated with aortic dissection.
	abdominalaorticaneurysm.researchtoday.net /archive/2/3/170.htm (221 words)

	ITP Immune Thrombocytopenic Purpura caused by Perchlorate (Irenat) (Site not responding. Last check: 2007-09-21)
		ITP Immune Thrombocytopenic Purpura caused by Perchlorate (Irenat)
		Immune Thrombocytopenic Purpura (ITP) is a disorder of the blood and refers to the purplish- looking areas of the skin and mucous membranes (such as the lining of the mouth) where bleeding has occurred as a result of decreased platelet count in the blood.
		If the purpura does not resolve promptly, then it is strongly advised to consider other potential causes of the purpura.
	www.drugintel.com /public/matters_arising/purpura.htm (409 words)

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