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| | Isopropyl methyl phosphonic acid (IMPA) (CASRN 1832-54-8), IRIS, Environmental Protection Agency |
 | | In studies conducted in rats, mice, dogs, and mink, as well as in quail and ducks, for periods ranging from 90 days to 26 weeks, and in a 3-generation rat reproduction study, DIMP was relatively nontoxic to all species (U.S. No unequivocal systemic effect nor sign of toxicity was evident in any species. |
 | | Since DIMP is rapidly and mostly metabolized to IMPA, it is reasonable to assume that the DIMP administered to mammals in these studies was metabolized to IMPA; therefore, the absence of effects from DIMP also may be considered to indicate a lack of effects from IMPA. |
 | | Section II provides information on three aspects of the carcinogenic assessment for the substance in question; the weight-of-evidence judgment of the likelihood that the substance is a human carcinogen, and quantitative estimates of risk from oral exposure and from inhalation exposure. |
| www.epa.gov /iris/subst/0530.htm (2661 words) |
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