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Topic: Infarct


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In the News (Thu 10 Dec 09)

  
  Acute Aspirin Treatment Abolishes, whereas Acute Ibuprofen Treatment Enhances Morphine-Induced Cardioprotection: Role ...
Infarct size expressed as a percentage of the area at risk in rats treated with vehicle (V), morphine (M; 0.3 mg/kg), ibuprofen plus morphine (I, 3 mg/kg and M, 0.3 mg/kg), or aspirin plus morphine (A, 1 or 3 mg/kg and M, 0.3 mg/kg).
Infarct size expressed as a percentage of the area at risk in rats treated with vehicle (V), morphine (M; 0.2 mg/kg), ibuprofen (I; 0.6 mg/kg), aspirin (A; 0.6 mg/kg), aspirin plus morphine (A, 0.6 mg/kg and M, 0.2 mg/kg), or ibuprofen plus morphine (I, 0.6 mg/kg and M, 0.2 mg/kg) administered 5 min before reperfusion.
Infarct size expressed as a percentage of the area at risk in rats treated with vehicle (V), morphine (M; 0.3 mg/kg), ibuprofen (I; 3 mg/kg), or ibuprofen plus morphine (I, 0.6 mg/kg and M, 0.2 mg/kg) administered 5 min before reperfusion.
jpet.aspetjournals.org /cgi/content/full/310/1/185   (3809 words)

  
 eMedicine - Bone Infarct : Article by Ali Nawaz Khan, MBBS, FRCP, FRCR   (Site not responding. Last check: 2007-10-08)
Bone infarcts associated with Gaucher disease are predominant in the Jewish population.
In the scaphoid bone, 10-15% of the fractures are complicated by osteonecrosis in the proximal pole of the scaphoid bone.
In patients with sickle cell disease, bone infarcts are typically multiple during the course of a sickle cell crisis.
www.emedicine.com /radio/topic86.htm   (7228 words)

  
 The impact of time to thrombolytic treatment on outcome in patients with acute myocardial infarction -- ...
Infarct size was significantly associated with elapsed time.
Infarct size in the < 2 hours subgroup was lower than in the other subgroups, among which there was no significant difference.
Mismatch of left ventricular function and infarct size demonstrated by technetium-99m isonitrile imaging after reperfusion therapy for acute myocardial infarction: identification of myocardial stunning and hyperkinesia.
heart.bmjjournals.com /cgi/content/full/84/2/142   (3734 words)

  
 Infarct   (Site not responding. Last check: 2007-10-08)
For the posterior wall, remember that vectors representing depolarization of the anterior and posterior portion of the left ventricle are in opposite directions.
Posterior wall infarcts are often associated with inferior wall infarcts (Q waves in II, III and aVF).
The second caveat is that, with a left bundle branch block, you cannot evaluate "infarct" on that ECG.
www.fammed.wisc.edu /pcc/ecg/infarct.html   (377 words)

  
 SIZE OF MYOCARDIAL INFARCT MEASURED USING MRI
A variety of methods are currently used to determine the size of an infarct by MRI, such as visual cues, but these estimates have been shown in previous studies to overestimate damage by an average of 11 percent.
Current methods for measuring the size of an infarct and assessing how much damage was done are highly subjective and arbitrary,” said senior study author and cardiologist João Lima, M.D., associate professor of medicine and radiology at The Johns Hopkins University School of Medicine and its Heart Institute.
When visual cues, the most commonly used method, were used, infarct size was measured with 69 percent accuracy.
www.hopkinsmedicine.org /Press_releases/2004/12_20a_04.html   (702 words)

  
 C-Reactive-Protein-Associated Increase in Myocardial Infarct Size After Ischemia/Reperfusion -- Barrett et al. 303 (3): ...
Infarct size is expressed as the TTC-negative region minus the TTC-negative region in sham occlusion rabbits (6 ± 1%).
A, the CRP-associated increase in infarct size was reduced by administration of heparin (300 U/kg) or N-acetylheparin (2 mg/kg) intravenously 2 h before the ischemic insult.
increase in plasma CRP correlated with an increase in infarct
jpet.aspetjournals.org /cgi/content/full/303/3/1007   (4645 words)

  
 Online Neuropathology Atlas
Subacute infarct in the territory of the internal carotid artery, Gross (6)
Hemorrhagic infarct in the territory of the internal carotid artery, Gross (5)
Hemorrhagic infarct in the territory of the anterior cerebral artery, Gross (4)
www.neuropat.dote.hu /atlas.html   (304 words)

  
 Which MR-derived Perfusion Parameters are the Best Predictors of Infarct Growth in Hyperacute Stroke? Comparative Study ...
infarct and in 80% of patients with an infarct decrease.
The area of infarct growth was defined as the red ROI minus the green ROI; and the area of viable hemodynamic disturbance, as the white ROI minus the red ROI.
The quantitative CBF was 7.3, 26, 34, and 49 mL/min/100 g in initial infarct, infarct growth, area of viable hemodynamic disturbance, and mirror ROIs, respectively.
radiology.rsnajnls.org /cgi/content/full/223/2/361   (6327 words)

  
 Relation Between Ischemia Time, Infarct Size, and Left Ventricular Function in Humans -- Hasche et al. 92 (4): 710 -- ...
Top, Example of early reperfusion of the infarct artery, with a rapid decrease in the magnitude of ST elevation.
Influence of infarct artery patency on the relation between initial ST segment elevation and final infarct size.
Reduction of infarct size with the early use of timolol in acute myocardial infarction.
circ.ahajournals.org /cgi/content/full/92/4/710   (6299 words)

  
 Critical Care | Full text | Case report: Capgras syndrome: a clinical manifestation of watershed cerebral infarct ...
Watershed cerebral infarcts are unusual ischaemic lesions, but which can easily be recognized by CT (a guide of vascular territories can be used) and magnetic resonance imaging [1].
Optical illusions with distortion of objects are described in posterior watershed infarct [1].
The main causes of cerebral border zone infarction are as follows [1]: serious cervical arterial artherosclerotic disease (specifically internal carotid artery occlusion), in which unilateral lesions are usually observed; and systemic hypotension, especially during cardiac surgery with extracoporeal circulation and cardiac arrest, which may cause bilateral lesions.
ccforum.com /content/5/4/232   (2159 words)

  
 eMedicine - Splenic Infarct : Article by Amber A Guth, MD, FACS   (Site not responding. Last check: 2007-10-08)
Although splenic infarct rates of 50% and 72% have been reported in chronic myelogenous leukemia and myelofibrosis respectively, few large series describing this entity exist.
Most commonly, these infarcts contract and fibrose over time, as demonstrated by the sickle hemoglobinopathies in which repeated episodes of infarction ultimately result in auto-infarction of the spleen.
Prior to the CT era, diagnosis of splenic infarct was made most commonly at laparotomy for intra-abdominal catastrophe or on postmortem examination.
www.emedicine.com /med/topic2750.htm   (2919 words)

  
 Dorlands Medical Dictionary
Brewer's i.’s dark-red, wedge-shaped areas, resembling infarcts, seen on section of a kidney in pyelonephritis.
an infarct that is red in color owing to the oozing of red corpuscles into the dead area; seen principally in the lung.
the formation of an infarct in a cardiac atrium, which may be due to coronary artery occlusion, periarteritis nodosa, obliterating endarteritis of the small branches of coronary arteries, or other conditions.
www.mercksource.com /pp/us/cns/cns_hl_dorlands.jspzQzpgzEzzSzppdocszSzuszSzcommonzSzdorlandszSzdorlandzSzdmd_i_07zPzhtm   (3740 words)

  
 Infarct-induced chronic heart failure increases bidirectional protein movement across the alveolocapillary barrier -- ...
I-albumin flux increased with infarct size (F-ratio P < 0.001) and was higher in the large infarct group compared with controls (*P < 0.001).
Scatter plots and median values of lavage fluid show the cell count (A) and percent neutrophils (B), and the bar graph shows means ± SE of the lavage fluid myeloperoxidase activity (C) in the three study groups as per Fig.
A: lavage cell count increased with infarct size (F-ratio P < 0.01) and was higher in the large infarct group compared with controls (*P < 0.01).
ajpheart.physiology.org /cgi/content/full/284/6/H2136   (5778 words)

  
 How well does the Oxfordshire Community Stroke Project classification predict the site and size of the infarct on brain ...
The overall accuracy is partly dependent on the definition of "appropriate infarcts".
Prediction of infarct topography using the Oxfordshire community stroke project classification of stroke subtypes.
Epidemiological characteristics of lacunar infarcts in a population.
jnnp.bmjjournals.com /cgi/content/full/68/5/558   (3457 words)

  
 Decreased capacity for mental effort after single supratentorial lacunar infarct may affect performance in everyday ...
The long term outcome after a single symptomatic lacunar infarct may be less favourable than is generally assumed.
Some 25% of strokes consist of lacunar infarcts in the deep regions of the brain.
Neuropsychological deficits after a subcortical infarct have been described before in case reports (table 1).
www.jnnp.com /cgi/content/full/65/5/697   (3346 words)

  
 Spontaneous late improvement of myocardial viability in the chronic infarct zone is possible, depending on persistent ...
Spontaneous late improvement of myocardial viability in the chronic infarct zone is possible, depending on persistent TIMI 3 flow and a low grade stenosis of the infarct artery -- Faraggi et al.
Spontaneous late improvement of myocardial viability in the chronic infarct zone is possible, depending on persistent TIMI 3 flow and a low grade stenosis of the infarct artery
infarct related artery is patent with a preserved coronary flow.
heart.bmjjournals.com /cgi/content/full/81/4/424   (4077 words)

  
 Wine and infarct
Myocardium infarct occurs when the cardiac muscle is deprived of oxygenated blood.
Doctor Rimm of the School of Public Health of Harvard - Cambridge - Massachusetts calculated that the risk of heart disease is reduced from 25 to 45% for people drinking 1 or 2 glasses of wine a day.
According to a study by Doctor Dean, for an equal consumption the risk of death by myocardium infarct is 1,03 for beer-drinkers, 1,00 for spirit-drinkers and only 0,47 for wine-drinkers.
www.terroir-france.com /wine/infarct.htm   (219 words)

  
 Infarction - Wikipedia, the free encyclopedia
The type of infarction is determined by the amount of hemorrhaging present.
Solid organs, such as the heart, spleen, and kidneys are infarcted from arterial occlusion and become white, or pale.
Lungs generally suffer more hemorrhaging or red infarctions.
en.wikipedia.org /wiki/Infarct   (159 words)

  
 Infarct Size After Acute Myocardial Infarction Measured by Quantitative Tomographic 99mTc Sestamibi Imaging Predicts ...
Infarct Size After Acute Myocardial Infarction Measured by Quantitative Tomographic 99mTc Sestamibi Imaging Predicts Subsequent Mortality -- Miller et al.
Plot of mortality curves for the entire study population and for the population divided into two groups on the basis of median infarct size.
Relation of size of transmural acute myocardial infarct to mode of death, interval between infarction and death and frequency of coronary arterial thrombus.
circ.ahajournals.org /cgi/content/full/92/3/334   (5855 words)

  
 Selective Activation of the Prostanoid EP3 Receptor Reduces Myocardial Infarct Size in Rodents -- Zacharowski et al. 19 ...
Reduction of experimental canine myocardial infarct size with prostaglandin E1: inhibition of neutrophil migration and activation.
Reduction by prostaglandin E1 or prostaglandin E0 of myocardial infarct size in the rabbit by activation of ATP-sensitive potassium channels.
Defibrotide reduces infarct size in a rabbit model of experimental myocardial ischaemia and reperfusion.
atvb.ahajournals.org /cgi/content/full/19/9/2141   (4495 words)

  
 Infarct Volume as a Surrogate or Auxiliary Outcome Measure in Ischemic Stroke Clinical Trials -- Saver et al. 30 (2): ...   (Site not responding. Last check: 2007-10-08)
Infarct Volume as a Surrogate or Auxiliary Outcome Measure in Ischemic Stroke Clinical Trials -- Saver et al.
of infarct volume in determining a favorable outcome was examined.
Transient disappearance of cerebral infarcts on CT scan: the so-called fogging effect.
stroke.ahajournals.org /cgi/content/full/30/2/293   (4040 words)

  
 Ligands of the peroxisome proliferator-activated receptors (PPAR-{gamma} and PPAR-{alpha}) reduce myocardial infarct ...
A) Area at risk (AR) and B) infarct size (IS) in rats subjected to regional myocardial ischemia (25 min) and reperfusion (2 h).
Different groups of animals were subjected to the surgical procedure alone (no left anterior descending coronary artery occlusion, sham n=8) or to left anterior descending (LAD) coronary artery occlusion and reperfusion and treated with either vehicle (10% DMSO control, n=11) or rosiglitazone (0.3, n=6; 1, n=6; or 3, n=5 mg/kg i.v.
Different groups of animals were subjected to the surgical procedure alone (no left anterior descending coronary artery occlusion, sham n=8) or to left anterior descending (LAD) coronary artery occlusion and reperfusion and treated with either vehicle (10% DMSO control, n=11) or ciglitazone (0.3, n=6; or 1, n=4 mg/kg i.v.
www.fasebj.org /cgi/content/full/16/9/1027   (6847 words)

  
 Current Controlled Trials in Cardiovascular Medicine | Full text | Early and long-term outcome of elective stenting of ...   (Site not responding. Last check: 2007-10-08)
As these recurrent events are mainly due to the presence of an unstable residual stenosis of the infarct-related coronary artery, an effective therapy should include an invasive procedure like angioplasty to optimize coronary flow to the infarct area in high risk patients [11].
Several post-infarction observational studies investigated viability as prognosticator and showed that the presence of viability in the infarct area was highly predictive for future coronary events like recurrent ischemia, recurrent infarction, left ventricular failure, and death [22-31].
Patients admitted to any of the participating centers with an acute or recent myocardial infarction, who are not treated by direct or rescue angioplasty, and who are stable during the first 48 hours after the acute event, are screened for the study.
cvm.controlled-trials.com /content/5/1/11   (4141 words)

  
 B-type natriuretic peptide limits infarct size in rat isolated hearts via KATP channel opening -- D'Souza et al. 284 ...
In the third infarct study, 8-Br-cGMP, a cell-permeable analog of cGMP, was perfused at 10
In the second series of infarct experiments, BNP was applied at a concentration of 10
infarcts that were 20% smaller than wild-type control animals.
ajpheart.physiology.org /cgi/content/full/284/5/H1592   (4196 words)

  
 eMedicine - Multi-infarct Dementia : Article by Giovanni d'Avossa, MD   (Site not responding. Last check: 2007-10-08)
Single ischemic or thromboembolic infarcts occurring in strategic areas of the dominant hemisphere (eg, angular gyri, mediodorsal thalamus, anterior thalamus) may cause a dementialike syndrome without the involvement of large volumes of cerebral matter.
Multiple lacunar infarcts, mainly in the frontal white matter and basal ganglia, lead to progressive cognitive decline and finally dementia.
In patients with VaD, multiple cortical, and more commonly subcortical, infarcts or single strokes affecting the thalamus, angular gyrus, and the territory supplied by the anterior cerebral arteries are observed.
www.emedicine.com /neuro/topic227.htm   (2410 words)

  
 Infarct restraint attenuates remodeling and reduces chronic ischemic mitral regurgitation after postero-lateral ...   (Site not responding. Last check: 2007-10-08)
Infarct restraint attenuates remodeling and reduces chronic ischemic mitral regurgitation after postero-lateral infarction -- Moainie et al.
Infarct restraint attenuates remodeling and reduces chronic ischemic mitral regurgitation after postero-lateral infarction
to infarct approximately 24% of the postero-lateral LV mass.
ats.ctsnetjournals.org /cgi/content/abstract/74/2/444   (839 words)

  
 cerebral peduncle infarct
It began with a spell of vertigo that lasted about a week (the kind where the room felt like it was spinning.) My PC doctor ordered another MRI about that time and it showed a tiny old infarct in the left cerebral peduncle.
The infarct in your cerebral peduncle should no cause all the symptoms you have described.
If this is truely an infarct, I cannot tell without reviewing the films, then you should be evaluated to determine why this occurred, and to determine your future risk of other strokes.
www.medhelp.org /forums/neuro/messages/33131.html   (369 words)

  
 Multi Infarct Dementia
Multi-infarct dementia (MID), a common form of dementia in the elderly, occurs when blood clots block small blood vessels in the brain and destroy brain tissue.
CADASIL (cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy) is an inherited form of MID.
This disease can cause stroke, dementia, migraine-like headaches, and psychiatric disturbances.
www.psychnet-uk.com /dsm_iv/multi_infarct_dementia.htm   (405 words)

  
 Differential Effects of Sarcolemmal and Mitochondrial KATP Channels Activated by 17beta -Estradiol on Reperfusion ...
Differential Effects of Sarcolemmal and Mitochondrial KATP Channels Activated by 17beta -Estradiol on Reperfusion Arrhythmias and Infarct Sizes in Canine Hearts -- Tsai et al.
is cardioprotective against infarct sizes and fatal reperfusion
infarct size-limiting and antiarrhythmic effects of estrogen were
jpet.aspetjournals.org /cgi/content/abstract/301/1/234   (391 words)

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