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Topic: Inhibins


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In the News (Wed 15 Feb 12)

  
  MEDLINE Search on Medscape.com
[Inhibins, activins and anti-Müllerian hormone: structure, signalling pathways, roles and predictive value in reproductive medicine]Anti-Müllerian hormone (AMH), inhibins and activins are members of the transforming growth factor (TGFbeta) superfamily and are known to have a variety of...
Inhibins in female and male reproductive physiology: role in gametogenesis, conception, implantation and early pregnancy.
Expression of inhibins, activins, insulin-like growth factor-I and steroidogenic enzymes in the equine placenta.
search.medscape.com /medline-search?queryText=Inhibins   (439 words)

  
 Concentrations of inhibins and steroids in follicular fluid during development of dominant follicules in heifers -- ...
Concentrations of inhibins and steroids in follicular fluid during development of dominant follicules in heifers -- Martin et al.
Concentrations of inhibins and steroids in follicular fluid during development of dominant follicules in heifers
that inhibins are involved in growth and atresia of dominant follicles
www.biolreprod.org /cgi/content/abstract/44/4/693   (459 words)

  
  Inhibins, genetics   (Site not responding. Last check: 2007-10-15)
Inhibin alpha-subunit and the inhibin coreceptor betaglycan are downregulated in endometrial carcinoma.
Inhibin B is comprised of the inhibin alpha subunit disulfide-linked to the inhibin/activin betaB subunit.
Inhibin is a gonadal hormone composed of an a-subunit and one of two beta-subunits (betaA, betaB), and its primary role is to inhibit FSH secretion by the pituitary.
lib.bioinfo.pl /meid:43316   (4313 words)

  
 The role of inhibins and activins in prostate cancer pathogenesis -- Dowling and Risbridger 7 (4): 243 -- ...
Inhibin and its structurally related protein, activin, are members of the transforming-growth-factor beta (TGFbeta) superfamily.
The aim of this review is to examine the relationship between inhibins, activins and their related proteins and the development of prostate cancer.
The importance of this review lies in demonstrating that inhibin, an endocrine hormone, and its related proteins may contribute to endocrine-related cancers, such as that of the prostate gland.
erc.endocrinology-journals.org /cgi/content/abstract/7/4/243   (424 words)

  
 Population Briefs | July 2002, Vol. 8, No. 1 | Illuminating the Role of Inhibins and Activins in Fertility
Bernard, however, is most interested in pursuing inhibins, which are produced in the ovary and testis, and activins, which appear to affect FSH through their local production within the pituitary gland.
Both inhibin and activin are part of a larger family of proteins that seem to act as tumor suppressors.
When inhibins are added, activin-stimulated gene activity stops almost entirely.
www.popcouncil.org /publications/popbriefs/pb8(1)_4.html   (813 words)

  
 Inhibins, physiology   (Site not responding. Last check: 2007-10-15)
Inhibin B is one of the growth factors mediating between Sertoli cells and germ cells.
Inhibin B levels are low in the first week after birth in male newborns, then increase up to the 6th month of age and then decline progressively to reach their nadir towards 3-6 years.
Current understanding of inhibin physiology and pathology in the human suggests that inhibin B may be of importance as a marker of Sertoli cell function in men with infertility and as a prognostic indicator in women undergoing ovulation induction therapy.
lib.bioinfo.pl /meid:197232   (1910 words)

  
 Groups   (Site not responding. Last check: 2007-10-15)
Activins and Inhibins are structurally related gonadal dimeric glycoproteins defined by their ability to modulate the synthesis and release of follicle-stimulating hormone (FSH) from the anterior pituitary gland.
Inhibins are heterodimers consisting of a common α-subunit linked to either a βA subunit (Inhibin A) or βB subunit (Inhibin B) by disulfide bridges, and in contrast to the Activins, inhibit FSH release.
Activins are bound with high affinity to follistatin with a possible regulatory role, while both inhibins and activins are found to bind reversibly with α2-macroglobulin [3].
www.dslabs.com /research_reagents/reagent_analyte_gp.aspx?analyte_group_id=49   (354 words)

  
 The testis as a major source of circulating inhibins in the male equine fetus during the second half of gestation -- ...
The testis as a major source of circulating inhibins in the male equine fetus during the second half of gestation -- Tanaka et al.
The testis as a major source of circulating inhibins in the male equine fetus during the second half of gestation
Inhibin B Regulating Follicle-Stimulating Hormone Secretion During Testicular Recrudescence in the Male Golden Hamster
www.andrologyjournal.org /cgi/content/abstract/23/2/229   (408 words)

  
 Unbound MEDLINE | Inhibins journal articles
Very high inhibin a concentration attributed to heterophilic antibody interference.
Inhibin as a diagnostic marker for ovarian cancer.
Granulosa cell tumors of the ovary: The clinical value of serum inhibin A and B levels in a large single center cohort.
www.unboundmedicine.com /medline/ebm/mesh/Inhibins   (204 words)

  
 Activins and Inhibins in Endocrine and Other Tumors -- Risbridger et al. 22 (6): 836 -- Endocrine Reviews
Inhibin potentially interferes with activin signaling by forming complexes with the activin receptors; the low affinity of inhibin for ActRII is enhanced by binding to betaglycan (BG).
inhibin and activin subunit genes, the follistatin gene, and
of inhibin in the diagnosis of ovarian tumors.
edrv.endojournals.org /cgi/content/full/22/6/836   (8202 words)

  
 Thieme-connect - Abstract   (Site not responding. Last check: 2007-10-15)
The development of assays specific for dimeric inhibin A and inhibin B defined the distinct physiology of these two hormones in the normal menstrual cycle.
Inhibin A and inhibin B expression and secretion along with their differential regulation by gonadotropins explain their unique serum patterns and their potential endocrine and ovarian autocrine-paracrine functions.
There is evidence that inhibin A and inhibin B play an endocrine role in the negative regulation of follicle-stimulating hormone (FSH) in nonhuman primates and humans.
www.thieme-connect.com /DOI/DOI?10.1055/s-2004-831894   (196 words)

  
 Activins and Inhibins and Their Signaling -- VALE et al. 1038 (1): 142 -- Annals of the New York Academy of Sciences
Activins and Inhibins and Their Signaling -- VALE et al.
Activins and inhibins, which were discovered by virtue of their
Inhibin antagonizes activin by binding to the proteoglycan,
www.annalsnyas.org /cgi/content/abstract/1038/1/142   (335 words)

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