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Topic: Inhibition


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In the News (Thu 31 Dec 09)

  
  Inhibitor - Wikipedia, the free encyclopedia   (Site not responding. Last check: 2007-11-03)
Inhibition Theory, a theory pertaining to the performance of a mental task
Lateral inhibition, a mechanism by which neurons are able to determine the origin of a stimulus
Social inhibition, a conditioned fear reaction to social marginalization or isolation.
en.wikipedia.org /wiki/Inhibition   (178 words)

  
 Enzyme inhibition
This inhibition is most commonly encountered in multi-substrate reactions where the inhibitor is competitive with respect to one substrate (e.g.
The fractional inhibition is identical at all substrate concentrations and cannot be overcome by increasing substrate concentration due to the reduction in V
The diminution in the rate of reaction with pH, described earlier, may be considered as a special case of noncompetitive inhibition; the inhibitor being the hydrogen ion on the acid side of the optimum or the hydroxide ion on the alkaline side.
www.lsbu.ac.uk /biology/enztech/inhibition.html   (1016 words)

  
 Enzyme Inhibition
In feedback inhibition, there is a second binding site on the enzyme where the inhibitor binds, so that the inhibitor is not necessarily similar in structure to the substrate.
In feedback inhibition, the inhibitor binds to the enzyme at a site away from the active site and acts by altering the shape of the enzyme in such a way that it is incapable of catalyzing the reaction.
Feedback inhibition is a natural part of the process by which an organism regulates the chemical reactions that take place in its cells.
dl.clackamas.cc.or.us /ch106-08/enzyme1.htm   (654 words)

  
 Inhibition - LoveToKnow 1911
It is more particularly applied to a form of ecclesiastical censure, suspending an offending clergyman from the performance of any service of the Church, or other spiritual duty, for the purpose of enforcing obedience to a monition or order of the bishop or judge.
Such inhibitions are at the discretion of the ordinary if he considers that scandal might arise from the performance of spiritual duties by the offender (Church Discipline Act 1860, re-enacted by the Clergy Discipline Act 1892, sect.
5, similar powers of inhibition are given where a sequestration remains in force for more than six months, and also, by the Benefices Act 1898, in cases where a commission reports that the ecclesiastical duties of a benefice are inadequately performed through the negligence of the incumbent.
www.1911encyclopedia.org /Inhibition   (163 words)

  
 Repetitive Sensory Input Increases Reciprocal Ia Inhibition In Individuals With Incomplete Spinal Cord Injury Journal ...
Reciprocal inhibition between agonist-antagonist muscle pairs is necessary for the performance of smooth alternating movement such as those involved in locomotion.1,2 Without this alternation movement patterns may be dysfunctional.
For example, D1 inhibition5 mediates reciprocal inhibition presumably via presynaptic mechanisms (Figure 1.2), with inhibition observed at latencies of approximately 10 ms to 25 ms between activation of the agonist and inhibition of the antagonist.
Recently, we showed that a temporary increase in Ia inhibition could be induced in nondisabled individuals by repetitive sensory stimulation of the peripheral nerve both with and without additional motor cortical stimulation.13 The pattern of peripheral sensory input was a critical factor in inducing changes in Ia inhibition in nondisabled subjects.
www.findarticles.com /p/articles/mi_qa4108/is_200409/ai_n9434946   (759 words)

  
 Lateral Inhibition   (Site not responding. Last check: 2007-11-03)
Lateral inhibition helps to explain a number of "optical illusions" and, more importantly, provides an excellent example of how the brain is organized to actively "make sense" of the information it gets, rather than to simply absorb and respond to it.
The reason for this is that ouput cells near the edge of the left small grey square are signalling decreasing light intensity as one moves into the square, while those near the edge of the right small grey square are signalling increasing light intensity as one moves into the square.
A very interesting and important property of a lateral inhibition network (compare the output plots at the bottom of both figures) is that their outputs will be pretty much the same in the two cases.
serendip.brynmawr.edu /bb/latinhib.html   (2044 words)

  
 Drugs - Enzyme Inhibition
Inhibition caused by drugs may be either reversible or irreversible.
Many substances which inhibit nucleic acid biosynthesis are very toxic since the drug is not very selective in its action between the parasite and host.
The counterfeit metabolite inhibits another enzyme or is an unusable fraudulent end product which cannot be utilized by the cell for growth or reproduction.
www.elmhurst.edu /~chm/vchembook/651enzymeinhibit.html   (300 words)

  
 Endogenous regulators of G protein signaling proteins regulate presynaptic inhibition at rat hippocampal synapses -- ...
Percent presynaptic inhibition was calculated as the difference between peak EPSC amplitudes under control conditions and in the presence of the drug divided by the control EPSC amplitude, multiplied by 100.
Steady-state inhibition in the presence of adenosine was 47 ±
that the onset of adenosine-induced presynaptic inhibition was
www.pnas.org /cgi/content/full/97/23/12810   (4094 words)

  
 Inhibition of HIV-1 Replication.
DNA oligonucleotides hybridize to target RNA by Watson-Crick base pairing to inhibit translation by simply blocking ribosomal reading or inducing degradation of the RNA part of duplexed DNA/RNAs by activation of RNase H. DNA with natural phosphodiester linkages has been found to be rapidly degraded by nucleases and to poorly cross cellular membranes.
Sequence-specific inhibition of gene expression by a novel antisense oligodeoxynucleotide phosphorothioate directed against a nonregulatory region of the human immunodeficiency virus type 1 genome.
Synergistic inhibition of HIV-1 by an antisense oligonucleotide and nucleoside analog reverse transcriptase inhibitors.
www.aapsj.org /view.asp?art=ps030107   (5692 words)

  
 Allelopathic Inhibition of the Nitrogen Cycle by Monoterpenes
The conservation of energy due to the inhibition of nitrification is therefore one argument for inhibition of nitrification.
He predicted that inhibition by monoterpenes was competitive and that monoterpenes should vary in degree of inhibition with differences in molecular structure.
The results also implied that the degree of inhibition of nitrification was inversely proportional to the inherent rate of nitrification in the soil.
www.colostate.edu /Depts/Entomology/courses/en570/papers_1998/adair.htm   (3417 words)

  
 Inhibition of Voltage-Dependent Calcium Channels by Prostaglandin E2 in Rat Melanotrophs -- Tanaka et al. 139 (12): ...
Note that inhibition of P/Q-type currents was almost entirely removed by the prepulse, whereas that of L-type currents was largely unaffected.
inhibition and was relatively resistant to a prepulse.
Physiological or pathophysiological significance of inhibition of melanotrophs by PGE
endo.endojournals.org /cgi/content/full/139/12/4801   (4819 words)

  
 F. M. Alexander Quotations: Inhibition - 6.11
But instead of employing inhibition, he adds to his difficulties by renewing his efforts on the old basis to put right what he is told is wrong, and he actually employs increased force in accordance with his own estimate of the amount needed to perform the act.
As long as he inhibits the sending of the old messages the old lines of communication are not used, and as he becomes more and more versed in the procedures of the technique the tendency to make use of them decreases, as does his dependence upon his feeling of rightness associated with them.
The employment of inhibition calls for the exercise of memory and awareness – the former for remembering the procedures involved in the technique and the proper sequence in which they should be used, and the latter in the recognition of what is happening.
www.mouritz.co.uk /6.11.quo.inhibition.html   (3737 words)

  
 Cytopathogenesis and Inhibition of Host Gene Expression by RNA Viruses -- Lyles 64 (4): 709 -- Microbiology and ...
108 of TBP that is responsible for the observed inhibition (144).
Inhibition by VSV M protein is shown at the RCC1 step because it resembles inhibition by a ts mutation in RCC1, but the actual target could be some other step in the Ran-GTP/Ran-GDP cycle.
The role of vesicular stomatitis virus matrix protein in inhibition of host-directed gene expression is genetically separable from its function in virus assembly.
mmbr.asm.org /cgi/content/full/64/4/709   (11182 words)

  
 Sensitivity to Voltage-Independent Inhibition Determined by Pore-Lining Region of the Acetylcholine Receptor -- Francis ...
Sensitivity to Voltage-Independent Inhibition Determined by Pore-Lining Region of the Acetylcholine Receptor -- Francis et al.
The trace marked a is the response to a co-application of ACh with inhibitor, and the trace marked b is the response to ACh alone 5 min later and is used as a measure of recovery from inhibition.
It should be noted that, in these experiments, measures of relative inhibition of peak current at t = 0 min do not quantitate steady-state inhibition (see Materials and Methods) but serve to demonstrate the fundamental sensitivity of both receptor subtypes to the TMP compounds.
www.biophysj.org /cgi/content/full/74/5/2306   (6728 words)

  
 Cyclooxygenase Inhibition and Cardiovascular Risk -- Antman et al. 112 (5): 759 -- Circulation
Common side effects (in varying relative frequencies) are gastrointestinal ulceration, inhibition of platelet aggregation, inhibition of uterine motility, inhibition of PG-mediated renal function, and hypersensitivity reactions.
Inhibition and uncoupling of oxidative phosphorylation by nonsteroidal anti-inflammatory drugs: study in mitochondria, submitochondrial particles, cells, and whole heart.
Differential inhibition by aspirin of vascular and platelet prostaglandin synthesis in atherosclerotic patients.
circ.ahajournals.org /cgi/content/full/112/5/759   (6836 words)

  
 Site-directed inhibition of DNA replication by triple helix formation -- DIVIACCO et al. 15 (14): 2660 -- The FASEB ...
Quantification of DNA replication inhibition from the pSV/PPT(+) plasmid is presented as a function of oligonucleotide concentration in the culture medium (•, np; O, po).
24 h later, replicated DNA was quantified and replication inhibition was reported as a function of PNA concentration in the electroporation cuvet (800 µl).
No inhibition was observed with the 9TC PNA at the highest concentration (800 nM); at the same concentration, the bis-PNA 9–9TC inhibited 60% of replication.
www.fasebj.org /cgi/content/full/15/14/2660   (5629 words)

  
 Cholinesterase Inhibition
While the effects of cholinesterase inhibiting products are intended for insect pests, these chemicals can also be poisonous, or toxic, to humans in some situations.
Any pesticide that can bind, or inhibit, cholinesterase, making it unable to breakdown acetylcholine, is called a "cholinesterase inhibitor," or "anticholinesterase agent." The two main classes of cholinesterase inhibiting pesticides are the organophosphates (OPs) and the carbamates (CMs).
Although the signs of cholinesterase inhibition are similar for both carbamate and organophosphate poisoning, blood cholinesterase returns to safe levels much more quickly after exposure to CMs than after OP exposure.
pmep.cce.cornell.edu /profiles/extoxnet/TIB/cholinesterase.html   (2721 words)

  
 inhibition. The American Heritage® Dictionary of the English Language: Fourth Edition. 2000.
The act of inhibiting or the state of being inhibited.
Chemistry The condition in which or the process by which a reaction is inhibited.
Biology The condition in which or the process by which an enzyme, for example, is inhibited.
www.bartleby.com /61/32/I0143200.html   (118 words)

  
 G Protein Preferences for Dopamine D2 Inhibition of Prolactin Secretion and DNA Synthesis in GH4 Pituitary Cells -- ...
In the latter case DA inhibited DNA synthesis, presumably due to replacement of PTX-inactivated G proteins by new protein synthesis during the subsequent 20-h assay period.
B, The concentration dependence of PTX action to inhibit D2S receptor-mediated inhibition of DNA synthesis in GH ZR7 cells was determined.
Florio T, Pan MG, Newman B, Hershberger RE, Civelli O, Stork PJ 1992 Dopaminergic inhibition of DNA synthesis in pituitary tumor cells is associated with phosphotyrosine phosphatase activity.
mend.endojournals.org /cgi/content/full/16/8/1903   (4101 words)

  
 Inhibition of human leukocyte 3-hydroxy-3-methylglutaryl coenzyme A reductase activity by ascorbic acid. An effect ...
Inhibition of human leukocyte 3-hydroxy-3-methylglutaryl coenzyme A reductase activity by ascorbic acid.
and 81% inhibition, respectively) and 0.1 and 10 mM dehydroascorbate (5 and
Fifty per cent inhibition of enzyme activity occurred at a
www.jbc.org /cgi/content/abstract/261/16/7127   (416 words)

  
 Enzyme Inhibition
The lecture handout, Data Analysis for Competitive Inhibition shows an example of the use of replots to determine the K
When the control is exerted by the end product of the pathway, the inhibition (or activation) is termed "feedback regulation".
An example to be considered later is the feedback inhibition by ATP of the glycolytic pathway.
www.nitorig.net /lec15.html   (962 words)

  
 Vasopeptidase Inhibition: A Double-Edged Sword? -- Campbell 41 (3): 383 -- Hypertension
Inhibition of neutral endopeptidase causes vasoconstriction of human resistance vessels in vivo.
Effects of neutral endopeptidase inhibition and combined angiotensin converting enzyme and neutral endopeptidase inhibition on angiotensin and bradykinin peptides in rats.
Inhibition of neutral endopeptidase 3.4.24.11 in conscious dogs with pacing induced heart failure.
hyper.ahajournals.org /cgi/content/full/41/3/383   (5489 words)

  
 Two-Dimensional Absorption-Inhibition
A novel inhibition procedure, called two-dimensional absorption-inhibition, is described.
Two-dimensional inhibition takes advantage of the best features of inhibition-titration and titration-inhibition, and is shown to be more sensitive than either of them.
Results obtained using all the inhibition methods on secretor saliva, semen, urine, urine stain, and perspiration stain specimens show that the new technique is especially powerful in correctly determining the ABH antigens in secretor body fluids having lower concentrations of soluble blood group antigens.
www.astm.org /JOURNALS/FORENSIC/PAGES/1386.htm   (248 words)

  
 Inhibition, orgasmic definition - Medical Dictionary definitions of popular medical terms
Inhibition, orgasmic definition - Medical Dictionary definitions of popular medical terms
MedicineNet Home > MedTerms medical dictionary A-Z List > Inhibition, orgasmic
MedicineNet does not provide medical advice, diagnosis or treatment.
www.medterms.com /script/main/art.asp?articlekey=25398   (59 words)

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