Where results make sense

About us   |   Why use us?   |   Reviews   |   PR   |   Contact us

Stem Cell Research Basics: Early Stem Cells Early stem cells are found in the inner cell mass of the blastocyst. Somatic cell nuclear transfer (SCNT) is a laboratory procedure that produces a blastocyst from an unfertilized egg and an ordinary adult somatic cell (e.g., from a single skin cell). The inner cell mass of the blastocyst is then removed to generate a pluripotent stem cell line. www.kumc.edu /stemcell/early.html   (861 words)

Gale - eNewsletters - CurricuLinks - Stem Cell Pro   (Site not responding. Last check: 2007-10-31) Although the inner cell mass cells can form virtually every type of cell found in the human body, they cannot form an organism because they are unable to give rise to the placenta and supporting tissues necessary for development in the human uterus. Cells from the inner cell mass of this blastocyst could, in theory, be used to develop pluripotent stem cell lines. In humans, neuronal stem cells have been isolated from fetal tissue and a kind of cell that may be a neuronal stem cell has been isolated from adult brain tissue that was surgically removed for the treatment of epilepsy. www.gale.com /enewsletters/curriculinks/2004_09/stemcell_pro.htm   (2876 words)

Red Blood Cell Indices: Encyclopedia of Medicine Cells of normal size are called normocytic, smaller cells are microcytic, and larger cells are macrocytic. Cells with a normal concentration of hemoglobin are called normochromic; cells with a lower than normal concentration are called hypochromic. Cells with too little hemoglobin are lighter in color with a larger pale area in the center. health.enotes.com /medicine-encyclopedia/red-blood-cell-indices   (1379 words)

Glossary [Stem Cell Information] The blastocyst is a sphere made up of an outer layer of cells (the trophoblast), a fluid-filled cavity (the blastocoel), and a cluster of cells on the interior (the inner cell mass). The ICM cells are used to generate embryonic stem cells. By combining a patient's somatic cell nucleus and an enucleated egg, a scientist may harvest embryonic stem cells from the resulting embryo that can be used to generate tissues that match a patient's body. stemcells.nih.gov /info/glossary.asp   (1825 words)

Stem Cell Information The blastocyst consists of a sphere made up of an outer layer of cells (the trophectoderm), a fluid-filled cavity (the blastocoel), and a cluster of cells on the interior (the inner cell mass). Human embryonic stem cell — A type of pluripotent stem cell derived from the inner cell mass of the blastocyst. Microenvironment — The molecules and compounds such as nutrients and growth factors in the fluid surrounding a cell in an organism or in the laboratory, which are important in determining the characteristicsof the cell. www.worldhealthspecialists.org /glossary.asp   (1168 words)

Stem Cell Glossary   (Site not responding. Last check: 2007-10-31) The blastocyst consists of a sphere made up of an outer layer of cells (the trophoblast), which will form the placenta, a fluid-filled cavity (the blastocoel), and a cluster of cells on the interior from which the stem cells are derived (the inner cell mass). Cells from the inner cell mass are isolated and used to develop new stem cell lines. The reason somatic cell nuclear transfer (sometimes referred to as therapeutic cloning) is being used to obtain stem cells is to address the vital issue of tissue incompatibility and possible rejection. www.stemcellresearchfoundation.org /WhatsNew/Glossary.htm   (1079 words)

ISSCR :: Glossary : Glossary The blastocyst is a spherical cell mass produced by cleavage of the zygote (fertilized egg). In the context of cells, heterologous is a mixed or divergent cell population or of a divergent origin. If the stem cells are placed back into the individual who gave the DNA for the somatic cell nuclear transfer, the embryonic stem cells and their derivatives are genetically identical and thus immunocompatible (they will not be rejected). www.isscr.org /glossary/index.htm#plasticity   (2890 words)

Stem Cell Research at UCSF | Glossary Embryonic stem cells are made by isolating and culturing cells from the inner cell mass. Cells found mainly in the bone marrow that give rise to a number of tissues, including bone, cartilage (the lining of joints), muscle, fat and connective tissue (tissue that is in between organs and structures in the body). Totipotent stem cells give rise to all cell types that are found in an embryo, fetus or adult organism, as well as the embryonic components of the amniotic sac and placenta. stemcellfacts.ucsf.edu /glossary.php   (586 words)

Stem Cell Primer Stem cells,which are cells that have the ability to divide for indefinite periods in culture and to give rise to specialized cells such as blood or skin or brain tissue, are best described in the context of normal human development. In 1998, James Thomson and coworkers at the University of Wisconsin isolated pluripotent stem cells directly from the inner cell mass of human embryos at the blastocyst stage. Given the enormous promise of stem cells for the development of new therapies to treat the most devastating diseases, it is important to simultaneously pursue all lines of research. forum.ra.utk.edu /2000spring/stem.html   (3231 words)

The Harry M. Zweig Memorial Fund for Equine Research - Currently Funded Projects While the cells are initially growing in culture, there are distinct cellular characteristics (morphology) which can be used to determine if the inner cell mass cells remain as totipotent ES cells, or if they have differentiated into other cell types. Because isolating the inner cell mass requires specialized equipment and expertise and because recognizing the morphologic characteristics of ES versus differentiated cell types requires a great deal of experience, our initial embryos were shipped to Dr. Neil Talbot at the USDA Gene Evaluation and Mapping Laboratory. Equine inner cell mass isolates were maintained as morphologically appearing ES cells (large nucleus:cytoplasm ratio, single large nucleoli) for four days when cultured on equine fibroblastic feeder cells. www.vet.cornell.edu /public/research/zweig/fortier03.html   (1200 words)

Factors affecting cellular outgrowth from porcine inner cell masses in vitro -- Schilperoort-Haun and Menino 80 (10): ... Porcine inner cell masses at 0 h (A) and accompanying outgrowths on laminin at 24 (B), 48 (C), 72 (D), and 96 h (E) of culture. Porcine inner cell masses cultured on laminin in 0 (A) and 500 µg/mL (B) arg-gly-asp at 72 h of culture. migration of a population of endodermal cells from the embryo’s jas.fass.org /cgi/content/full/80/10/2671   (3919 words)

PCBE: Monitoring Stem Cell Research: Glossary ICM cells: Cells from the inner cell mass, a population of cells inside the blastula that give rise to the body of the new organism rather than to the chorion or other supporting structures. Cells that can produce all the cell types of the developing body, such as the ICM cells of the blastocyst, are said to be pluripotent. Primitive streak: A band of cells appearing in the embryo at the start of the third week of development, that marks the axis along which the spinal chord develops. www.bioethics.gov /reports/stemcell/glossary.html   (2469 words)

What is a Stem Cell? Embryonic stem cells are derived from a group of cells called the inner cell mass, which is part of the blastocyst, a lump of cells that forms four-five days after fertilization of an egg by a sperm. Once the cells from the inner cell mass are removed from the blastocyst they can be cultured in petri dishes into embryonic stem cells (see figure). Recently, stem cells have been found in the adult inner ear and it remains to be seen whether stimulation of such internal stem cells could be an option to restore hearing in patients. www.drf.org /hearing_health/archive/2004/winter04_whatisastemcell_ex.htm   (613 words)

Photo Collage 3) The blastocyst's inner stem cell mass is then removed and placed in culture where the undifferentiated stem cells proliferate. These inner cell mass cells are pluripotent — they can give rise to many types of cells but not all types of cells necessary for fetal development. Then, using carefully worked out laboratory conditions, a somatic cell (any cell other than an egg or a sperm cell) is placed next to the egg from which the nucleus had been removed, and the two are fused. web.pdx.edu /~kee/photocollage.htm   (706 words)

The Illinois Regenerative Medicine Institute (IRMI) : Glossary Endoderm — Lower layer of a group of cells derived from the inner cell mass of the blastocyst; it gives rise to lungs and digestive organs. Microenvironment — The molecules and compounds such as nutrients and growth factors in the fluid surrounding a cell in an organism or in the laboratory, which are important in determining the characteristics of the cell. Stromal cells — Non-blood cells derived from blood organs, such as bone marrow or fetal liver, which are capable of supporting growth of blood cells in vitro. www.idph.state.il.us /irmi/glossary.html   (1213 words)

lifeissues.net | Irving: Open Communication To Participants of the CBHD/NCCB Bioethics Stem Cell Coalition: F. The claim that certain cells in the early developing embryo are "fated" or irreversibly determined, is questioned by some human embryologists, and put in doubt by recent studies using human embryonic, fetal and adult stem cells. However, in general, the inner cell mass gives rise to most of the embryo proper and is therefore called the embryoblast. The outer cell mass is the primary source for the membranes of the placenta and is therefore called the trophoblast." (p. www.lifeissues.net /writers/irv/irv_71recordstraight3.html   (2631 words)

NEJM -- New Human Embryonic Stem-Cell Lines -- More Is Better Embryonic stem cells are derived from the inner cell mass of Embryonic stem cells are derived from the inner cell mass of the blastocyst; cells composing the inner cell mass are isolated and then plated on culture medium, below which is a layer of feeder cells. Isolation of a pluripotent cell line from early mouse embryos cultured in medium conditioned by teratocarcinoma stem cells. content.nejm.org /cgi/content/full/350/13/1275   (964 words)

Stem Cell Basics   (Site not responding. Last check: 2007-10-31) A stem cell is a type of cell that has the ability to either divide for indefinite periods in culture to create more stem cells, or to give rise to specialized cells. The inner cell mass will form all of the tissues of the human body, therefore, these are the cells that develop into the fetus. Multipotent stem cells are committed to give rise to cells that have a particular function, for example, blood stem cells give rise to red blood cells, white blood cells and platelets, and skin stem cells give rise to the different types of skin cells. www.molbio.princeton.edu /courses/mb427/2001/projects/09/SObasics.htm   (454 words)

LIFE BEGINS AT CONCEPTION During this phase, the zygote undergoes continual cell division, implants in the uterus, and forms the primary germ layers, which give rise to the organs of the human body. Cell division continues, and a cavity known as a blastocele forms in the center of the morula. The presence of the blastocyst indicates that two cell types are forming: the embryoblast (inner cell mass on the inside of the blastocele), and the trophoblast (the cells on the outside of the blastocele). www.jesuschristsavior.net /prolife.html   (2203 words)

Stem-Cell Unlike embryonic stem cells, which are unmanageable and do not produce the right kind of cells, stem cells from adult bone marrow do not trigger such problems, even after the cells differentiate. Bone marrow derived stem cells are used in cancer and autoimmune treatment protocols, to replace or repair organs that are damaged by chemotherapy during cancer therapy. Adult stem cell therapy is being used to treat brain tumors, retinoblastoma, ovarian cancer, sarcomas, multiple myeloma, leukemia, breast cancer, neuroblastoma, renal cell carcinoma, juvenile rheumatoid arthritis, and other diseases. www.pathlights.com /abortion/Stem-cell.htm   (3087 words)

Maintenance of the Inner Cell Mass in Human Blastocysts from Fragmented Embryos -- Hardy et al. 68 (4): 1165 -- Biology ... allocation of cells to the trophectoderm and inner cell mass ICM cell numbers within a fairly narrow range [28]. A quantitative analysis of cell allocation to trophectoderm and inner cell mass in the mouse blastocyst. www.biolreprod.org /cgi/content/full/68/4/1165   (4049 words)

Growth Retardation of Inner Cell Mass Cells in Polyspermic Porcine Embryos Produced In Vitro -- Han et al. 60 (5): 1110 ... Number of ICM nuclei of PPN-derived blastocysts cultured in vitro or in vivo were significantly lower than those of 2PN-derived blastocysts (p < 0.01), but no differences were detected in the number of TE or total nuclei (p > 0.05). The results suggest that the growth of ICM cells in PPN eggs slowed in early development. Origin of the ectoplacental cone and secondary giant cells in mouse blastocysts reconstituted from isolated trophoblast and inner cell mass. www.biolreprod.org /cgi/content/full/60/5/1110   (3657 words)

Possible Stem Cell Uses Stem cells are derived from the inner cell mass of a Blastocyst. This inner cell mass can be cultivated by removing it from the inside of the Blastocyst, allowing researchers to grow specialized cells or tissues which could be used to treat many different illnesses. Stem cells could also be used to test drugs for safety by using human cell lines. cs1.mcm.edu /~jacksone/website/page2.html   (93 words)

Gene Expression: December 2005   (Site not responding. Last check: 2007-10-31) The zona pellucida is the human equivalent of an egg shell. The inner cell mass is the important part. Send this entry to: Del.icio.us Spurl Ma.gnolia Digg Newsvine Reddit www.gnxp.com /blog/archives/2005_12_01_gene-expression_archive.php   (10480 words)

Try your search on: Qwika (all wikis)

About us   |   Why use us?   |   Reviews   |   Press   |   Contact us   Copyright © 2005-2007 www.factbites.com Usage implies agreement with terms.