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Topic: Insulin antagonist

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Literary antagonist

H2 antagonists

receptor antagonist

antagonistic contradiction

leukotriene antagonist

beta receptor antagonist

androgen antagonist

Insulin antagonist

Biphasic insulin

Insulin resistance type B

insulin glargine

insulin analog

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	Receptor antagonist - Wikipedia, the free encyclopedia
		In medicine and biology, a receptor antagonist is a substance that inhibits the normal physiological function of a receptor.
		Antagonists that compete with an agonist for a receptor are competitive antagonists.
		Antagonists stop agonists from acting on certain receptors by blocking them.
	en.wikipedia.org /wiki/Receptor_antagonist (203 words)

	children with DIABETES - Diabetes Dictionary: I
		In this second case, the insulin binds with the proteins that are supposed to protect the body from outside substances (antibodies).
		The insulin flows from the pump through a plastic tube (called a catheter) that is connected to a needle inserted into the skin and taped in place.
		Insulin is delivered at different rates, which can be either manually set or preprogrammed: a low, steady rate (called the basal rate) for continuous day-long coverage, and extra boosts of insulin (called bolus doses) to cover meals or when extra insulin is needed.
	www.childrenwithdiabetes.com /dictionary/i.htm (1763 words)

	BD Diabetes - The Diabetes Dictionary : I -
		If the insulin is an injected form of insulin and not made by the body, the body sees the insulin as an outside or "foreign" substance.
		The insulin flows from the pump through a plastic tube that is connected to a needle inserted into the body and taped in place.
		Insulin is delivered at two rates: a low, steady rate (called the basal rate) for continuous day-long coverage, and extra boosts of insulin (called bolus doses) to cover meals or when extra insulin is needed.
	www.bddiabetes.com /us/understanding/dict_i.asp (1497 words)

	EFFECTS OF GLUCOSE, INSULIN, GLUCAGON AND NICOTINE ON CULTURED FIBROBLASTS
		The aim of this investigation is to study androgen metabolism in human gingival fibroblasts exposed to a hyperglycaemic environment and their response to insulin, the antagonist glucagon and nicotine; this may be extrapolated to their metabolic responses in vivo, in uncontrolled diabetes (obtained local Ethical Committee approval).
		Duplicate incubations of four cell lines of monolayer cultures of fibroblasts were performed in Eagle's MEM with radiolabelled testosterone as substrate; in the presence or absence of a) glucose (1-100micrograms/ml) / insulin, (3micrograms/ml) b) the insulin antagonist glucagon (0.5-10micrograms/ml) / insulin (3micrograms/ml) and c) insulin (0.5-50micrograms/ml) / nicotine (250micrograms/ml), alone and in the above combinations.
		Insulin was able to overcome hyperglycaemic effects in this model, demonstrated by the yields of androgen metabolites, which can be used as a parameter of risk for wound healing in diabetics.
	www.endocrine-abstracts.org /ea/0004/ea0004dp3.htm (349 words)

	Insulin Attenuates Formalin-Induced Nociceptive Response in Mice through a Mechanism that Is Deranged by Diabetes ...
		a dopamine 2 receptor antagonist), pindolol (1 mg/kg i.p., a 5-hydroxytryptamine
		1 receptor antagonist) and ketanserin (1 mg/kg i.p., a 5-hydroxytryptamine
		(1 mg/kg i.p., a 5-hydroxytryptamine 3 receptor antagonist).
	jpet.aspetjournals.org /cgi/content/full/281/1/315 (3540 words)

	A1 adenosine receptor antagonism improves glucose tolerance in Zucker rats -- Xu et al. 274 (2): E271 -- AJP - ...
		of the insulin receptor or of an insulin receptor substrate (IRS)
		Insulin receptor kinase is hyperresponsive in adipocytes of young obese Zucker rats.
		Adenosine reversal of in vivo hepatic responsiveness to insulin.
	ajpendo.physiology.org /cgi/content/full/274/2/E271 (5084 words)

	Glucagon-Like Peptide-1, But Not Glucose-Dependent Insulinotropic Peptide, Regulates Fasting Glycemia and Nonenteral ...
		The GLP-1 receptor antagonist exendin(9, 10, 11, 12, 13,
		Northern blot analysis of pancreatic insulin and glucagon mRNA transcripts in +/+ and GLP-1R-/- mice treated with exendin(9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39) [Ex 9–39(A)] or GIPR Ab (B).
		Pancreatic insulin content in +/+ and GLP-1R-/- mice treated with exendin(9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39) (A) or GIP Ab (B).
	endo.endojournals.org /cgi/content/full/141/10/3703 (5983 words)

	A New Selective Peroxisome Proliferator-Activated Receptor {gamma} Antagonist with Antiobesity and Antidiabetic ...
		antagonist or by invalidation of one allele of the PPAR
		SR-202 Is an Insulin Sensitizer in Vivo, Decreasing Hyperglycemia and Hyperinsulinaemia in ob/ob Mice
		Serum glucose (A) and insulin (B) levels at the fed state in ob/ob mice on d 0 (white bars) or on d 20 after the treatment with vehicle (gray bars) or SR-202 (fl bars).
	mend.endojournals.org /cgi/content/full/16/11/2628 (5873 words)

	Inhibition of RXR and PPAR{gamma} ameliorates diet-induced obesity and type 2 diabetes -- Yamauchi et al. 108 (7): 1001 ...
		mice with the RXR antagonist or the PPAR
		A synthetic antagonist for the peroxisome proliferator-activated receptor gamma inhibits adipocyte differentiation.
		Glucose metabolism and insulin sensitivity in transgenic mice overexpressing leptin with lethal yellow agouti mutation: usefulness of leptin for the treatment of obesity-associated diabetes.
	www.jci.org /cgi/content/full/108/7/1001 (6606 words)

	Levodopa with carbidopa diminishes glycogen concentration, glycogen synthase activity, and insulin-stimulated glucose ...
		n = 14 (basal), 15 (insulin), 14 (insulin and levodopa-carbidopa), 6 (levodopa-carbidopa), and 6 (insulin, levodopa-carbidopa, and propranolol).
		Tyr(612) and Tyr(632) in human insulin receptor substrate-1 are important for full activation of insulin-stimulated phosphatidylinositol 3-kinase activity and translocation of GLUT4 in adipose cells.
		Caffeine-induced impairment of insulin action but not insulin signaling in human skeletal muscle is reduced by exercise.
	jap.physiology.org /cgi/content/full/97/6/2339 (4218 words)

	Glossary I
		When a person's body has an allergic or bad reaction to taking insulin made from pork or beef or from bacteria, or because the insulin is not exactly the same as human insulin or because it has impurities.
		To treat the disease, the person must inject insulin, follow a diet plan, exercise daily, and test blood glucose several times a day.
		Many people with noninsulin-dependent diabetes produce enough insulin, but their bodies do not respond to the action of insulin.
	members.aol.com /jfoster166/i.html (1568 words)

	Role of Nitric Oxide, Adenosine, and ATP-Sensitive Potassium Channels in Insulin-Induced Vasodilation -- McKay and ... (Site not responding. Last check: 2007-10-26)
		Interactions between insulin and norepinephrine on blood pressure and insulin sensitivity: studies in lean and obese men.
		Decreased effect of insulin to stimulate skeletal muscle blood flow in obese man: a novel mechanism for insulin resistance.
		Insulin Induces the Release of Vasodilator Compounds From Platelets by a Nitric Oxide-G Kinase-VAMP-3-dependent Pathway
	hyper.ahajournals.org /cgi/content/full/28/2/202 (4170 words)

	A Selective Peroxisome Proliferator-Activated Receptor-{gamma} (PPAR{gamma}) Modulator Blocks Adipocyte Differentiation ...
		LG100641 Blocks Thiazolidinedione-Induced 3T3-L1 Cell Differentiation (A) but not Differentiation Induced with Dexamethasone, Insulin, and IBMX (B) or the RXR Ligand LG100268 (C) 3T3-L1 cells were induced to differentiate with rosiglitazone (BRL 49653), LG100641, LG100268, dexamethasone, insulin, and IBMX or combinations of inducer and antagonist at the concentrations shown.
		This induction was abolished in the presence of the antagonist.
		this repression was attenuated in the presence of the antagonist.
	mend.endojournals.org /cgi/content/full/14/9/1425 (3767 words)

	Tissue-specific effects of in vivo adenosine receptor blockade on glucose uptake in Zucker rats -- Crist et al. 12 ...
		of the adenosine receptor antagonist to increase glucose uptake
		Glucose uptake was determined during the final 40 min of a 3 h euglycemic hyperinsulinemic clamp in which insulin was infused at a rate sufficient to maximally stimulate whole body and tissue glucose uptake.
		Terrettaz, J., and Jeanrenaud, B. In vivo hepatic and peripheral insulin resistance in genetically obese fa/fa rats.
	www.fasebj.org /cgi/content/full/12/13/1301 (4437 words)

	IGF-I/IGF-Binding Protein-3 Combination Improves Insulin Resistance By GH-Dependent and Independent Mechanisms -- ...
		Administration of the GHR antagonist for 2 wk was accompanied
		Dominici FP, Cifone D, Bartke A, Turyn D 1999 Loss of sensitivity to insulin at early events of the insulin signaling pathway in the liver of growth hormone-transgenic mice.
		Insulin Resistance in the Liver-Specific IGF-1 Gene-Deleted Mouse Is Abrogated by Deletion of the Acid-Labile Subunit of the IGF-Binding Protein-3 Complex: Relative Roles of Growth Hormone and IGF-1 in Insulin Resistance
	jcem.endojournals.org /cgi/content/full/87/9/4356 (4007 words)

	Effects of simulated hyperglycemia, insulin, and glucagon on endothelial nitric oxide synthase expression -- Ding et ...
		Effects of simulated hyperglycemia, insulin, and glucagon on endothelial nitric oxide synthase expression -- Ding et al.
		insulin level, and the insulin antagonist glucagon on endothelial
		Insulin down-regulates the inducible nitric oxide synthase pathway: nitric oxide as cause and effect of diabetes?
	ajpendo.physiology.org /cgi/content/full/279/1/E11 (3956 words)

	Alternate-Day Administration of Pegvisomant Maintains Normal Serum Insulin-Like Growth Factor-I Levels in Patients with ...
		alter the binding characteristics of the antagonist with the
		Insulin was measured by the Immulite immunoassay (Diagnostics
		(3) and morbidities such as insulin resistance (4, 12, 13).
	jcem.endojournals.org /cgi/content/full/90/3/1588 (3992 words)

	Inhibition of growth hormone action improves insulin sensitivity in liver IGF-1-deficient mice -- Yakar et al. 113 (1): ...
		Inactivation of insulin action in the LID mice is restored by introduction of GHa (LID + GHa mice).
		Suppressors of cytokine signaling-1 and -6 associate with and inhibit the insulin receptor.
		Insulin resistance in acromegaly: defects in both hepatic and extrahepatic insulin action.
	www.jci.org /cgi/content/full/113/1/96 (7010 words)

	Selective Angiotensin II Receptor Antagonism Reduces Insulin Resistance in Obese Zucker Rats -- Henriksen et al. 38 ...
		Increase above basal due to insulin for 2-DG uptake also was calculated in the acute vehicle-treated group (open bars) and each of the acute irbesartan-treated groups (shaded and filled bars, right top and bottom).
		DeFronzo RA, Ferrannini E. Insulin resistance: a multifaceted syndrome responsible for NIDDM, obesity, hypertension, dyslipidemia, and atherosclerotic cardiovascular disease.
		Insulin responsiveness in skeletal muscle is determined by glucose transporter (Glut4) protein level.
	hyper.ahajournals.org /cgi/content/full/38/4/884 (4770 words)

	Energy Citations Database (ECD) - Energy and Energy-Related Bibliographic Citations
		Energy Citations Database (ECD) Document #6718510 - Antagonistic effects of a covalently dimerized insulin derivative on insulin receptors in 3T3-L1 adipocytes
		Availability information may be found in the Availability, Publisher, Research Organization, Resource Relation and/or Author (affiliation information) fields and/or via the "Full-text Availability" link.
		Antagonistic effects of a covalently dimerized insulin derivative on insulin receptors in 3T3-L1 adipocytes
	www.osti.gov /energycitations/product.biblio.jsp?osti_id=6718510 (179 words)

	Diabetes Dictionary (Site not responding. Last check: 2007-10-26)
		Putting liquserid into the body with a needle and syringe.
		Putting a fluserid into a vein with a needle and syringe.
		We subscribe to the HONcode principles of the Health On the Net Foundation
	www.healthatoz.com /healthatoz/Atoz/dc/caz/diab/dia1/i_dic.jsp (1687 words)

	Growth hormone receptor antagonist improves insulin resistance in acromegaly (Site not responding. Last check: 2007-10-26)
		Growth hormone receptor antagonist improves insulin resistance in acromegaly
		Pegvisomant news vertical portal can now be syndicated quickly and easily using our new Really Simple Syndication feeds.
		For any further understanding that could lead to the prevention, treatment, and/or cure of the disorders, we recommend that affected individuals seek the advice or counsel of his or her own personal physician(s).
	pegvisomant.diseasemap.com /page_78689.html (123 words)

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