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Topic: Insulin resistance


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In the News (Mon 23 Nov 09)

  
  Insulin resistance - Wikipedia, the free encyclopedia
Insulin resistance is the condition in which normal amounts of insulin are inadequate to produce a normal insulin response from fat, muscle and liver cells.
Insulin resistance in muscle reduces glucose uptake whereas insulin resistance in liver reduces glucose storage, with both effects serving to elevate blood glucose.
Insulin resistance is often found in people with visceral adiposity (i.e., a high degree of fatty tissue underneath the abdominal muscle wall - as distinct from subcutaneous adiposity or fat between the skin and the muscle wall), hypertension, hyperglycemia and dyslipidemia involving elevated triglycerides, small dense low-density lipoprotein (sdLDL) particles, and decreased HDL cholesterol levels.
en.wikipedia.org /wiki/Insulin_resistance   (1536 words)

  
 Insulin Resistance Project
Insulin is a hormone produced by the beta-cells of the islets of Langerhans of the pancreas.
Insulin is required for the uptake and utilization of the blood glucose by tissues of the body.
Insulin resistance can occur either because of a defect in insulin binding to its receptor or to "post-receptor" defects; with the latter, the spread of insulin-stimulated signals throughout the cell is deranged.
www8.utsouthwestern.edu /utsw/cda/dept27717/files/148934.html   (611 words)

  
 Insulin Resistance - Nutritional Information - HERSHEY'S
Insulin resistance occurs when the normal amount of insulin secreted by the pancreas is not able to "unlock the door" to cells.
Therefore, for individuals who are insulin resistant, a diet low in saturated fat (less than 10 percent of total calories) and more moderate in total fat content (30 percent - 35 percent of total calories) may be beneficial.
- Insulin resistance occurs when the normal amount of insulin secreted by the pancreas is not able to remove glucose from the blood into the muscle cells for use as energy or storage for future use.
www.hersheys.com /nutrition/insulin.asp   (830 words)

  
 Insulin resistance syndrome in women
Insulin resistance — also called syndrome X — is so pervasive today that we evaluate nearly every woman who visits our clinic to determine her level of risk.
Women who are insulin resistant are at much greater risk of obesity, diabetes, hypertension (high blood pressure), heart disease, high cholesterol, breast cancer and polycystic ovarian syndrome (PCOS).
Insulin resistance often accompanies the most common complaints we hear at Women to Women — fatigue and weight gain.
www.womentowomen.com /insulinresistance/index.asp   (1990 words)

  
 eMedicine - Insulin Resistance : Article Excerpt by Samuel T Olatunbosun
Insulin resistance is a state in which a given concentration of insulin produces a less-than-expected biological effect.
Insulin resistance and hyperinsulinemia are thought to be responsible for the hyperandrogenism that is characteristic of polycystic ovary disease (PCOD).
Two major variants of insulin receptor abnormalities associated with acanthosis nigricans have been described—the classic type A insulin resistance syndrome, which is due to an absent or dysfunctional receptor, and type B insulin resistance syndrome, which results from autoantibodies to the insulin receptor.
www.emedicine.com /med/byname/insulin-resistance.htm   (1958 words)

  
 Insulin resistance definition - Medical Dictionary definitions of popular medical terms
Insulin resistance: The diminished ability of cells to respond to the action of insulin in transporting glucose (sugar) from the bloodstream into muscle and other tissues.
Insulin resistance typically develops with obesity and heralds the onset of type 2 diabetes.
Insulin Resistance - Insulin resistance is associated with obesity, fatty liver, type 2 diabetes, heart disease, skin tags, polycystic ovary disease, and growth abnormalities.
www.medterms.com /script/main/art.asp?articlekey=18822   (360 words)

  
 Insulin Resistance Syndrome
Insulin resistance syndrome, or Syndrome X, is a condition where muscle cells have lost insulin sensitivity to the point that glucose no longer enters them.
Insulin resistance syndrome is caused by elevated insulin levels due to high blood pressure; high triglycerides and low HDL, or “good”, cholesterol; excessive fat tissue in the abdominal region or a family history of diabetes.
Symptoms of insulin resistance include Type II diabetes, central obesity, high levels of lipids in the blood coupled with low levels of HDL cholesterol, high blood pressure, elevated levels of blood factors that promote blood clotting and high levels of uric acid in the blood.
www.hmc.psu.edu /healthinfo/i/insulinresistance.htm   (438 words)

  
 Insulin Resistance and Pre-Diabetes   (Site not responding. Last check: 2007-11-05)
Insulin resistance is a silent condition that increases the chances of developing diabetes and heart disease.
Many people with insulin resistance and high blood glucose have excess weight around the waist, high LDL (bad) blood cholesterol levels, low HDL (good) cholesterol levels, high levels of triglycerides (another fat in the blood), and high blood pressure, all conditions that also put the heart at risk.
Insulin resistance plays a role in the development of cardiovascular disease, which damages the heart and blood vessels.
diabetes.niddk.nih.gov /dm/pubs/insulinresistance   (2739 words)

  
 The Body: Insulin Resistance and Diabetes   (Site not responding. Last check: 2007-11-05)
Insulin resistance is a condition in which the body's cells do not respond properly to the hormone and cannot take up glucose, which then builds up in the bloodstream.
Insulin resistance and diabetes are a concern because untreated high blood sugar can lead to a wide range of long-term health problems, including kidney dysfunction, retina damage leading to blindness, nerve damage, erectile dysfunction in men, and pregnancy complications in women.
As noted previously, insulin resistance and diabetes were not common in people with HIV before the advent of HAART, and many studies have found an association between blood glucose abnormalities and PI therapy.
www.thebody.com /sfaf/winter04/insulin.html   (7200 words)

  
 American Heart Association
This is why insulin resistance is considered a core metabolic dysfunction of type 2 diabetes.
Insulin resistance is a core metabolic dysfunction associated with type 2 diabetes and an increased risk for heart disease and stroke.
Insulin resistance is associated with blood lipid imbalances, such as an increased ratio of small low-density lipoprotein (LDL or "bad" cholesterol), low levels of high-density lipoprotein (HDL or "good" cholesterol), and increased levels of triglycerides, which cause atherosclerosis.
www.s2mw.com /heartofdiabetes/resistance.html   (388 words)

  
 children with DIABETES - Diabetes Dictionary: I
Insulin lowers the level of glucose (sugar) in the blood, whereas glucagon raises it; therefore, glucagon is an antagonist of insulin.
The insulin flows from the pump through a plastic tube (called a catheter) that is connected to a needle inserted into the skin and taped in place.
Insulin resistance is also linked to high blood pressure and high levels of fat in the blood (see Syndrome X).
www.childrenwithdiabetes.com /dictionary/i.htm   (1765 words)

  
 Diabetes and Detecting Insulin Resistance
Insulin resistance syndrome is a term used to describe a combination of medical conditions that have a common link -- an increased risk of premature heart disease.
In insulin resistance, the body's cells have a diminished ability to respond to the action of the insulin hormone.
People with this syndrome have insulin resistance and high levels of insulin in the blood as a marker of the disease rather than a cause.
www.webmd.com /content/article/59/66846?z=1667_50910_6504_00_14   (661 words)

  
 Insulin Resistance
But the beta cells in her pancreas are producing lots of insulin—enough of it to overcome her insulin resistance and escort the glucose from the food she eats to the cells that need it.
Europeans may have a low incidence of insulin resistance and diabetes because they were among the first to adopt agriculture and their diet has been high in carbohydrate for 10,000 years.
Since insulin resistance is one of the underlying causes of diabetes, it shouldn't be a big surprise that the best treatment for it is very much like that generally recommended for diabetes itself.
www.mendosa.com /ir.htm   (2014 words)

  
 The Covert Plague - Discover Magazine - science news articles online technology magazine articles The Covert Plague   (Site not responding. Last check: 2007-11-05)
Cells gradually become resistant to insulin, which is produced in the body to process glucose levels that rise in the blood after a meal.
Insulin can open up a cell's outer membrane like a key in a door lock and set in motion the machinery that feeds the cell glucose, which is converted to energy.
Another method is for cells to throttle back the processing of glucose during lean times by becoming insulin resistant, which blocks insulin from entering the cell and in essence rations the supply of glucose to last longer while also creating a powerful hunger impulse to drive people to find food.
www.discover.com /issues/dec-05/features/diabetes-insulin-resistance   (1322 words)

  
 Insulin Resistance   (Site not responding. Last check: 2007-11-05)
In some cases (about 1/3 of the people with insulin resistance), when the body cells resist or do not respond to even high levels of insulin, glucose builds up in the blood resulting in high blood glucose or type 2 diabetes.
Therefore, for individuals who are insulin resistant, a diet low in saturated fat (less than 10 percent of total calories) and more moderate in total fat content (40% of total calories) may be beneficial.
Insulin resistance occurs when the normal amount of insulin secreted by the pancreas is not able to remove glucose from the blood into the cells for use as energy or storage for future use.
syndromex.stanford.edu /InsulinResistance.htm   (984 words)

  
 Articles "The Insulin Resistance Syndrome"
What seems to connect the various features of the syndrome together is something called insulin resistance: that is, a reduced sensitivity in the tissues of the body to the action of insuln, which is, importantly, to bring glucose into those tissues to be used as a source of energy.
It is not clear how insulin resistance contributes to the presence of high blood pressure, but it is clear that the high insulin levels resulting from insulin resistance contribute to abnormalites in blood lipids—cholesterol and triglycerides.
This approach to caring for people with the insulin resistance syndrome, that of comprehensive evaluation and risk factor management, is essential if we are to meet and overcome the real health danger which accompanies this constellation of metabolic abnormalities—cardiovascular disease.
www.woundcare.org /newsvol1n3/ar1.htm   (668 words)

  
 Insulin resistance symptoms, causes, diagnosis and treatment on MedicineNet.com
Insulin is a hormone that is produced by the beta cells, which are cells that are scattered throughout the pancreas.
Insulin also is important in regulating the cells of the body including their growth.
Insulin resistance (IR) is a condition in which the cells of the body become resistant to the effects of insulin, that is, the normal response to a given amount of insulin is reduced.
www.medicinenet.com /insulin_resistance/article.htm   (365 words)

  
 Insulin Resistance Syndrome 
Insulin is a hormone that helps the sugar in your blood — which comes from the food you eat — enter the cells of your body, where it is used for energy.
Insulin resistance is now estimated to occur in half of all obese people and is considered a major risk factor for heart disease, high blood pressure and diabetes.
Insulin resistance is now estimated to occur in half of all obese people and is considered a major risk factor for heart disease, high blood pressure and type II diabetes.
www.psha-inc.com /guai-support/sf/InsulinResistanceSyndrome.htm   (7519 words)

  
 TREATMENT OF INSULIN RESISTANCE
The insulin resistance syndrome (IRS) puts you at very high risk for a heart attack and is associated with storing fat in the belly, rather than the hips; having high blood triglyceride levels and low level of the good HDL cholesterol; high blood pressure and an increased tendency to form clots.
As I mentioned earlier, insulin is a bad hormone, so the safest drugs are those that lower both insulin and sugar.
The relation between insulin resistance and cardiovascular complications of the insulin resistance syndrome.
www.drmirkin.com /diabetes/D222.html   (638 words)

  
 eMedicine - Insulin Resistance : Article by Samuel T Olatunbosun
Type B insulin resistance (autoantibodies to the insulin receptor): Patients usually have symptomatic diabetes mellitus, although ketoacidosis is unusual.
Measurement of response to direct intravenous infusion of insulin: The limitations of this measurement are a confounding factor in data interpretation and a variation in secretion of antagonist hormones in response to hypoglycemia.
For patients with insulin resistance without overt diabetes, the metabolic syndrome criteria for cardiovascular risk stratification is less sensitive than that of the Framingham Risk Score, which takes into account age, total cholesterol, tobacco use, HDL cholesterol, and blood pressure, but not diabetes.
www.emedicine.com /med/topic1173.htm   (6502 words)

  
 Insulin Resistance - WrongDiagnosis.com
Body is not sensitive enough to insulin; resists its use in processing sugar.
Detailed information about the causes of Insulin Resistance including medication causes and drug interaction causes can be found in our causes pages.
With a diagnosis of Insulin Resistance, it is also important to consider whether there is an underlying condition causing Insulin Resistance.
www.wrongdiagnosis.com /i/insulin_resistance/intro.htm   (686 words)

  
 Insulin Resistance Syndrome - Vitacost   (Site not responding. Last check: 2007-11-05)
Preliminary studies in animals and humans suggest that insulin resistance is worsened with increased use of saturated fat and improved with increased unsaturated omega-3 fatty acids from fish, while the role of other unsaturated fats is less clear.
Insulin resistance syndrome predicts the risk of coronary heart disease and stroke in healthy middle-aged men: the 22-year follow-up results of the Helsinki Policemen Study.
Insulin sensitivity is associated with blood pressure response to sodium in older hypertensives.
www.vitacost.com /science/hn/Concern/Insulin_Resistance_Syndrome.htm   (3563 words)

  
 Insulin Resistance Syndrome
Insulin resistant diabetics are 2-5 times more likely to die from heart attack or stroke than are non diabetics.
Additionally, insulin resistance may be worsened by reduced physicial activity, aging, tobacco smoking, or drugs such as diuretics, certain anti-hypertensives, or steroids.
It is a complicated and expensive study in which insulin and glucose is infused intravenously at several different doses to see what levels of insulin control different levels of glucose.
www.wdxcyber.com /ngen10.htm   (789 words)

  
 Metabolic Syndrome – Cause of Heart Disease, Cardiovascular Disease, Hypertension & more…
Insulin Resistance is an underlying cause of Metabolic Syndrome and there are many factors that contribute to its presence in the body.
This process leaves too few sites for insulin to carry out its normal function, which is to attach itself to the cell wall and act as "a key in a lock" allowing glucose to pass through the cell wall and be converted into energy.
When target cells are unresponsive to insulin, the pancreas responds by pouring even more insulin into the bloodstream, leading to high levels of the hormone in the blood, a condition called compensatory hyperinsulinemia.
www.metabolic-syndrome.insulitelabs.com   (2209 words)

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