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Topic: Interferon beta-1a

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Interferon beta-1a - Wikipedia, the free encyclopedia Interferon beta-1a is a drug in the interferon family used to treat multiple sclerosis. Rebif ( interferon beta-1a) is a disease -modifying drug used to treat relapsing forms of multiple sclerosis (MS) and is similar to the interferon beta protein produced by the human body. Interferons have been shown to have about a 30-35% reduction in the rate of MS relapses, and to slow the progression of disability in MS patients. en.wikipedia.org /wiki/Avonex

Interferon Beta 1-A - multiple sclerosis encyclopaedia Interferon beta-1a is the generic name of the immuno-modulatory drugs Avonex and Rebif which are used to treat multiple sclerosis. www.mult-sclerosis.org /InterferonBeta1A.html

FELLESKATALOGEN: Rebif «Serono» - Interferon. Interferon beta-1a har samme aminosyresekvens som naturlig humant interferon beta. Influensalignende symptomer inntrer ofte i forbindelse med behandling med interferon beta-1a, og kan innebære en ekstra belastning ved hjertesykdom. Interferon beta-1a er ennå ikke undersøkt på pasienter med primær progressiv multippel sklerose og bør ikke brukes på slike pasienter. www.felleskatalogen.no /ecom/StaticPages/NO/EA323682-24A2-42D0-BB92-A96BD162F953/BD8C0A83-17C0-4F5E-A622-702052781BB7/HighlightHelper.asp?target=NO/EA323682-24A2-42D0-BB92-A96BD162F953/BD8C0A83-17C0-4F5E-A622-702052781BB7/3B93FC80-E697-4F11-A590-28CB5C315BF3.asp&frameset=1&words=rebif

Rebif Online, Description, Chemistry, Ingredients - Interferon beta-1a - RxList Monographs (interferon beta-1a) is a purified 166 amino acid glycoprotein with a molecular weight of approximately 22,500 daltons. (interferon beta-1a) is formulated as a sterile solution in a prefilled syringe intended for subcutaneous (sc) injection. It is produced by recombinant DNA technology using genetically engineered Chinese Hamster Ovary cells into which the human interferon beta gene has been introduced. www.rxlist.com /cgi/generic3/rebif.htm

Clinical Trial: Safety Study of Interferon Beta 1a to for Acute Stroke Interferon beta 1a is approved for use in patients with multiple sclerosis to prevent further brain injury caused by inflammation; the drug may also help prevent further brain injury in patients with acute stroke. The dose of interferon beta 1a is increased in successive groups of patients, so that the first group to enter the study receives 11 micrograms (mcg) of the drug, the next receives 22 mcg, then 44 mcg, 66 mcg, and 88 mcg. This study will examine the safety of the drug interferon beta 1a in patients with acute ischemic stroke to determine the highest dose patients can tolerate without serious side effects and to determine the best way to give the medication. www.clinicaltrials.gov /ct/show/NCT00097318?order=7

MedlinePlus Drug Information: Interferon beta-1a Intramuscular Injection Interferon beta-1a intramuscular injection comes as a powder to be mixed into a solution for injection, and a prefilled injection syringe. Interferon beta-1a is in a class of medications called immunomodulators. Remove the caps from the vials of interferon beta-1a powder and sterile water. www.nlm.nih.gov /medlineplus/druginfo/medmaster/a693040.html

Starting Interferon Beta-1a Inititally May Slow Multiple Sclerosis Progression Initiation of interferon beta-1a at initial diagnosis of multiple sclerosis may reduce neurological and clinical symptoms of disease progression. Interferon beta reduces activity in multiple sclerosis, as measured clinically and by magnetic resonance imaging (MRI). Clinicians found that fewer patients (34 percent) in the interferon groups developed clinically definite multiple sclerosis in the interferon group than in the placebo group (45 percent). www.ilneurologo.com /pr28.htm

Interferon Beta-1a (Rebif) Associated Rarely With Severe Hepatic Injur Interferon beta-1a is indicated for the reduction of the frequency of clinical exacerbations of multiple sclerosis and to delay the accumulation of physical disability in patients with relapsing forms of multiple sclerosis. Interferon Beta-1a (Rebif) Associated Rarely With Severe Hepatic Injury On Dec. 23, the FDA approved revisions to the safety labeling for interferon beta-1a injection (Rebif, made by Serono, Inc.), warning of the risk of severe hepatic injury rarely associated with its use. Treatment with interferon beta-1a should be discontinued in patients who develop jaundice and other signs of liver dysfunction due to the potential for rapid progression to liver failure. archive.mail-list.com /hbv_research/msg07826.html

Interferon - Avonex (Interferon beta-1a) Learn about interferon, AVONEX® (Interferon beta-1a), part of the glycoproteins group that are produced by different cell types in response to various stimuli such as exposure to a virus, bacterium, parasite, or other antigen, and that prevent viral replication in newly infected cells and, in some cases, modulate specific cellular functions.. www.ms-activesource.com /avonex/interferon.html

News - Study Confirms Benefits of High-Dose, High-Frequency Beta Interferon Regimen in Treatment for Multiple Sclerosis Clinical activity significantly worsened during the year on interferon beta-1a and although it improved during the year after returning to high-dose, high-frequency beta interferon, the MRI activity persisted in some patients, failing to return to the total absence of disease activity demonstrated after three years of chronic interferon beta-1b treatment. In conclusion, the reduction in beta interferon dose and frequency may be associated with increased signs of clinical and MRI disease activity. The study was prompted by the hypothesis that once MS is controlled for several years using a high-dose, high-frequency beta interferon regimen, it might be possible to maintain the beneficial immunological and clinical effects using lower doses or less frequent applications of beta interferon. www.docguide.com /news/content.nsf/news/8525697700573E1885256ED700498133

Prescribing Information - Avonex® (Interferon beta-1a) (Interferon beta-1a) should be used with caution in patients with depression. (Interferon beta-1a) is contraindicated in patients with a history of hypersensitivity to natural or recombinant interferon beta, human albumin, or any other component of the formulation. (Interferon beta-1a) should be used with caution in patients with depression (see Warnings). www.vidyya.com /archives/0927_5.htm

Drug Directory: Interferon beta- 1a Interferon beta-1a is a specific interferon used in the treatment of relapsing multiple sclerosis to slow the development of physical disability and to decrease the frequency of exacerbations. Interferon beta-1a is in the FDA pregnancy category C. This means that it is not known whether interferon beta-1a will harm an unborn baby. Your pharmacist has additional information about interferon beta-1a written for health professionals that you may read. www.netpediatrics.com /drugs/i-30.htm

MedlinePlus Drug Information: Interferon, Beta-1a (Systemic) Although there is no specific information comparing use of interferon beta-1a in the elderly with use in other age groups, this medicine is not expected to cause different side effects or problems in older people than it does in younger adults. Interferon beta-1a (in-ter-FEER-on BAY-ta) is used to treat the relapsing forms of multiple sclerosis (MS). Interferon beta-1a is also used to treat genital warts. www.nlm.nih.gov /medlineplus/druginfo/uspdi/203537.html

Avonex, abc drugs of Multiple Sclerosis Interferon beta-1a is used in the treatment of multiple sclerosis to decrease the number and severity of attacks. Interferon beta-1a (Avonex®) is for injection into a muscle. Flu-like symptoms are common with interferon beta-1a therapy. www.pychealth.com /msandopcs.html

Chinese Patients Have Better Response to Interferon Beta-1a in Chronic HCV Unresponsive to Interferon Alfa This multicentre, randomized, parallel-group, dose-finding study evaluated the efficacy of interferon beta-1a in the treatment of chronic hepatitis C patients unresponsive to interferon-alfa. “In conclusion, write the authors, “interferon beta-1a provided considerable clinical benefit in Chinese patients with chronic hepatitis C unresponsive to interferon alfa. Chinese Patients Have Better Response to Interferon Beta-1a in Chronic HCV Unresponsive to Interferon Alfa www.hivandhepatitis.com /hep_c/news/2004/092004_c.html

MedicalPost.com: AAN: Plan can I.D. non-response to interferon Based on the first year clinical data, 21 (12%) patients in the 22 mcg interferon beta-1a group and 19 (10%) patients in the 44 mcg interferon beta-1a group were considered to be at high concern for a sub-optimal response. Overall, 180 patients in the 22 mcg interferon beta-1a and 182 patients in the 44 mcg interferon beta-1a groups were included in the analysis. In the following years, three patients on 22 mcg interferon beta-1a and three patients on 44 mcg interferon beta-1a who were assigned high concern status did not have a relapse. www.medicalpost.com /mpcontent/article.jsp?content=20050508_192054_2464

Multiple sclerosis Interferon beta 1a (Avonex, Rebif), interferon beta 1b (Betaseron) and glatiramer acetate (Copaxone) are currently used in the management of multiple sclerosis and are believed to alter the course of disease, reduce future disability and improve quality of life. The National Multiple Sclerosis Society recommends treatment with one of the licensed “disease modifying” drugs as soon as possible after the diagnosis of a relapsing form (the most common kind) of multiple sclerosis. These drugs help to lessen the frequency and severity of multiple sclerosis attacks, reduce the accumulation of lesions (areas of damage) in the brain, and slow the progression of disability. www.antigenics.com /diseases/ms.html

avonex interferon beta-1a, avonex interferon beta-1a No Prescription Rx, avonex interferon beta-1a mexico rx, avonex interferon beta-1a generic prescription, rx mexico prescriptions, free shipping avonex interferon beta-1a Interferon beta - 1a ( Avonex ®) is produced by recombinant DNA technology... Interferon beta - 1a is a 166 amino acid... The Avonex formulation of interferon beta - 1a is used as an intramuscular (into the muscle) injection... zeroprescriptions.com /A/avonex-interferon-beta-1a.html

National MS Society Rebif (Interferon beta-1a) Pregnancy Registries for the Interferon Beta Products Prescribed for Women with MS The FDA issued guidelines requiring the manufacturers of Avonex, Betaseron, and Rebif to develop pregnancy registries to monitor women who have taken one of these drugs within a week of becoming pregnant or while they were pregnant. It is made up of exactly the same amino acids (major components of proteins) as the interferon beta found in the human body. However, some patients treated with interferons, including Rebif, have become seriously depressed, and depression and suicidal thoughts are known to occur with some frequency in MS. www.nationalmssociety.org /meds-interferonbeta1arib.asp

High-dose interferon beta-1b for multiple sclerosis patients There are three interferon beta therapies known to be effective in reducing MS symptoms: interferon beta-1a 30 mcg administered intramuscularly once a week; interferon beta-1a 22 mcg or 44 mcg given subcutaneously three times a week; and interferon beta-1b 250 mcg administered subcutaneously on alternate days. Over 2 years, 51% of individuals administered interferon beta-1b remained relapse-free compared with 36% given interferon beta-1a; 55% compared with 26%, respectively, remained free from new proton density/T2 brain lesions at the MRI assessment. In a 2-year prospective study, 188 patients with relapsing-remitting MS were randomised to receive either interferon beta-1b or interferon beta-1a. www.eurekalert.org /pub_releases/2002-04/l-hib042402.php

Interferon beta 1a Interferon beta-1a (Rebif® and Avonex®) is produced by Chinese hamster ovary (CHO) cell lines by recombinant genetic techniques. IFN beta-1a is virtually identical to natural human IFN beta. Like natural IFN beta, they have a 10- to 14-times higher specific biological activity compared with that of IFN beta-1b (Betaferon®). www.rebif.net /international/branded/doctors/treatment/available_therapies/immunomodulatory_therapy/interferon_beta_a.jsp

Frequently Asked Questions Interferons are naturally occurring proteins and glycoproteins produced by cells in response to biological triggers. The clinical significance of neutralizing antibodies to interferons in MS is unknown. Copaxone is not an interferon - it is a synthetic compound that is a mixture of 4 amino acids. www.avonex.com /msavProject/avonex.portal?_nfls=false&_nfpb=true&_pageLabel=threeColLayout&path=/SCSRepository/en_US/avonex/includes/faq.xml

Interferon beta-1a Interferon beta-1a should be used with caution in patients with a history of depression, since it has been linked to an increase in suicidal impulses. Interferon beta-1a may pass into breast milk; caution is advised. It acts in the same way as the body's natural interferons, which are proteins released by the immune system to fight viruses, cancer cells, and other types of disease. www.wholehealthmd.com /refshelf/drugs_view/0,1524,702,00.html

Neutralising antibodies to interferon beta during the treatment of multiple sclerosis -- Giovannoni et al. 73 (5): 465 -- Journal of Neurology, Neurosurgery, and Psychiatry Neutralizing antibodies to interferon (IFN) alpha-2a and IFN beta-1a or IFN beta-1b in MS are not cross-reactive. Neutralizing antibodies to interferon beta-1a and interferon beta-1b in MS patients are cross-reactive. interferon beta-1b and interferon beta-1a is not surprising jnnp.bmjjournals.com /cgi/content/full/73/5/465

Directory of open access journals The patient was a 21-year-old man with MS and no past history of affective disorders who was given interferon beta-1a in the dose of 11 mug three times per week. As a new relapse occurred the dose of interferon beta-1a was increased to 22 mug three times a week. We report a case of depression and suicidal ideation in coincidence with the start of increased doses of interferon beta-1a and their complete reversal following the drug withdrawal. www.doaj.org /abstract?id=11321&toc=y

INTERFERON BETA-1A (Injection) (Injectable) Prescription Drug Information, Cost, Price, Side Effects, and More. INTERFERON BETA-1A (Injection) (Injectable) is used for the Treatment Interferon Beta-1a (in-ter-FEER-on BAY-ta-1a) Reduces frequency of flare-ups (relapses) in people who have multiple sclerosis (MS). Store INTERFERON BETA-1A (Injection) (Injectable) at room temperature away from sunlight and moisture unless otherwise stated by manufacturer's instructions or labelling. www.healthdigest.org /INTERFERON-BETA-1A-(Injection)-(Injectable)_4151_PRO.php

Interferon-beta bei Multipler Sklerose Interferone sind körpereigene Zytokine, welche die Bildung von Proteinen regulieren. Die genauen Wirkmechanismen der Interferone sind nicht bekannt. Dadurch ergeben sich besonders bei Arzneimitteln, die eine Wirkung auf den Krankheitsverlauf zeigen, ethische Probleme. www.infomed.org /pharma-kritik/pk01a-96.html

Avonex (interferon beta-1a), revisions to the labelling - FDA Interferon beta-1a may cause severe hepatic injury or failure, and a new registry is being created for women who become pregnant during treatment, according to the FDA.Yael Waknine The FDA has approved revisions to the safety labeling for interferon beta-1a injection (Rebif), filgrastim injection (Neupogen), and 50- and 100-mg ibuprofen chewable tablets (Children's Advil, Ju... Results of a European study in this week?s issue of THE LANCET provide further evidence that patients with early symptoms of multiple sclerosis given a weekly injection with interferon beta are le... www.medical-buzz.com /v56533.html

Interferon Beta 1a ( Interferon Beta 1a) was first launched in 1998 in Europe, and is now the market leader outside the US for the treatment of relapsing forms of MS. The two drugs currently on the market and used to treat MS with Interferon Beta 1a are Rebif Welcome to www.rebif.net > Assisting people with MS > Interferons www.rebif.net /international/branded/general/assisting_people_with_MS/interferons/interferon_beta_1a.jsp

Interferon Treatments In Multiple Sclerosis 2g2 Interferon-beta-1b (Betaferon) therapy in Relapsing/Remitting Multiple Sclerosis: findings of a prospective, multi-center study of disease progression The time at which 30% of patients had converted to Clinically Definite Multiple Sclerosis was 569 days in the Interferon group and 252 in the placebo group (p=0.034). Fewer patients developed Clinically Definite Multiple Sclerosis in the Interferon group than in the placebo group (52/154 [34%] vs 69/154 [45%]; p=0.047). www.geocities.com /thjuland/inf2g2.html

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