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Topic: Interleukin

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	Interleukin - Wikipedia, the free encyclopedia
		Interleukins are a group of cytokines that were first seen to be expressed by white blood cells (leukocytes, hence the -leukin) as a means of communication (inter-).
		The name is sort of a relic though; it has since been found that interleukins are produced by a wide variety of bodily cells.
		The function of the immune system depends in a large part on interleukins, and rare deficiencies of a number of them have been described, all featuring autoimmune diseases or immune deficiency.
	en.wikipedia.org /wiki/Interleukin (221 words)

	Interleukin 18 is a primary mediator of the inflammation associated with dextran sulphate sodium induced colitis: ...
		Interleukin 18 is a primary mediator of the inflammation associated with dextran sulphate sodium induced colitis: blocking interleukin 18 attenuates intestinal damage -- Sivakumar et al.
		Interleukin 18 is a primary mediator of the inflammation associated with dextran sulphate sodium induced colitis: blocking interleukin 18 attenuates intestinal damage
		Interleukin 1 and interleukin 18 as mediators of inflammation and the aging process
	gut.bmjjournals.com /cgi/content/abstract/50/6/812 (455 words)

	Interleukin 1: Facts and details from Encyclopedia Topic (Site not responding. Last check: 2007-11-07)
		Interleukin-1 (IL-1) is secreted by the macrophage[Click link for more facts about this topic]s, EHandler: no quick summary.
		It is commercially produced as anakinra[For more facts and a topic of this subject, click this link], EHandler: no quick summary.
		(which is a human recombinant form of interleukin 1 receptor antagonist.
	www.absoluteastronomy.com /encyclopedia/i/in/interleukin_1.htm (343 words)

	Interleukin
		Interleukin 10, Recombinant, Murine (IL-10, Cytokine Synthesis Inhibitory Factor, CSIF)
		Interleukin 10, Recombinant, Porcine (IL-10, Cytokine Synthesis Inhibitory Factor, CSIF)
		Interleukin 10, Recombinant, Rat (IL-10, Cytokine Synthesis Inhibitory Factor, CSIF)
	www.usbio.net /Category.aspx?catName=Growth+Factors-Interleukin (502 words)

	Serum interleukin 10 and interleukin 11 in patients with acute pancreatitis -- Chen et al. 45 (6): 895 -- Gut
		Serum interleukin 10 and interleukin 11 in patients with acute pancreatitis -- Chen et al.
		Serum interleukin 10 and interleukin 11 in patients with acute pancreatitis
		Interleukin 10 (IL-10) is a recently characterised potent anti-inflammatory cytokine.
	gut.bmjjournals.com /cgi/content/full/45/6/895 (2575 words)

	Leukemia Inhibitory Factor, Interleukin 6, and Other Cytokines Using the GP130 Transducing Receptor: Roles in ...
		Interleukin 6, but not ciliary neurotrophic factor or leukaemia inhibitory factor, is responsible for the acute phase response to turpentine-induced myositis.
		Interleukin (IL)-6 gene expression in the central nervous system is necessary for fever response to lipopolysaccharide or IL-1 beta: a study on IL-6-deficient mice.
		Neurologic disease induced in transgenic mice by cerebral overexpression of interleukin 6.
	stemcells.alphamedpress.org /cgi/content/full/17/3/127 (6319 words)

	Prognostic Value of Serum Interleukin-6 in Diffuse Large-cell Lymphoma -- Preti et al. 127 (3): 186 -- Annals of ...
		Expression of an exogenous interleukin 6 in human Epstein Barr virus B cells confers growth advantage and in vivo tumorigenicity.
		Interleukin 6 gene expression in normal and neoplastic B cells.
		Serum level of interleukin 6 as a prognostic factor in metastatic renal cell carcinoma.
	www.annals.org /cgi/content/full/127/3/186 (4826 words)

	Hereditary predisposition to low interleukin-10 production in children with extended oligoarticular juvenile idiopathic ...
		Interleukin 10 (IL-10) and viral IL-10 strongly reduce antigen-specific human T cell proliferation by diminishing the antigen-presenting capacity of monocytes via downregulation of class II major histocompatibility complex expression.
		Interleukin 10 increases CCR5 expression and HIV infection in human monocytes.
		Regulation of interleukin 10 release by tumor necrosis factor in humans and chimpanzees.
	rheumatology.oxfordjournals.org /cgi/content/full/40/5/574 (2601 words)

	Role of Tumor Necrosis Factor Alpha, Interleukin-1beta , and Interleukin-6 in a Mouse Model of Group B Streptococcal ...
		Role of interleukin 12 in experimental neonatal sepsis caused by group B streptococci.
		Interleukin-1-induced interleukin-6 is required for the inhibition of proteoglycan synthesis by interleukin-1 in human articular cartilage.
		Interleukin 1 induced leukocyte infiltration and cartilage proteoglycan degradation in the synovial joint.
	iai.asm.org /cgi/content/full/67/9/4545 (3689 words)

	Interleukin-1 Inhibition at Treatment for Rheumatoid Arthritis on Johns Hopkins Arthritis
		The interleukin gene family is comprised of IL-1a, IL-1b, and IL–1 receptor antagonist (IL–1ra).
		The third member of the interleukin gene family is IL-1ra.
		Interleukin 1 signaling occurs exclusively via the type I receptor.
	www.hopkins-arthritis.som.jhmi.edu /rheumatoid/il1.html (3951 words)

	IL6 - Interleukin 6 (interferon, beta 2) - aka: IFNB2 - Cancer GeneticsWeb
		Clinical correlates of elevated serum levels of interleukin 6 in patients with untreated Hodgkin's disease.
		Serum evaluation of interleukin 6 in ovarian cancer patients.
		Serum level of interleukin 6 as a prognosis factor in metastatic renal cell carcinoma.
	www.cancerindex.org /geneweb/IL6.htm (428 words)

	Interleukin
		Th1 (interleukin (IL)-2) and Th2 (IL-6) cytokines and monokines (IL-1 =DF, IL-1 receptor antagonist (RA)) were studied during IFN therapy.
		Materials and Methods: Sixty-one CHC patients who were treated by fixed protocol of IFN therapy (IFN [alpha] 9-10 mega U/day for 2 weeks followed by 3 times/week for 22 weeks) and showed similar clinical activities were carefully chosen from 542 IFN-treated CHC and enrolled in this study.
		The aim of this study was determine the immunoregulatory functions of Interleukin 12 (IL-12) with regard to local cytokine production in human liver.
	www.hepatitis-c.de /interleu.htm (1158 words)

	Pulmonary expression of interleukin-13 causes inflammation, mucus hypersecretion, subepithelial fibrosis, physiologic ...
		Interleukin 4, but not interleukin 5 or eosinophils, is required in a murine model of acute airway hyperreactivity.
		Recombinant human interleukin 5 is a selective activator of human eosinophil function.
		Phenotypic and physiologic characterization of transgenic mice expressing interleukin 4 in the lung: lymphocytic and eosinophilic inflammation without airway hyperreactivity.
	www.jci.org /cgi/content/full/103/6/779 (6301 words)

	Accelerated Prion Disease in the Absence of Interleukin-10 -- Thackray et al. 78 (24): 13697 -- The Journal of Virology
		Interleukin (IL)1beta, IL-1alpha, and IL-1 receptor antagonist gene polymorphisms in patients with temporal lobe epilepsy.
		Heightened expression of tumor necrosis factor alpha, interleukin 1 alpha, and glial fibrillary acidic protein in experimental Creutzfeldt-Jakob disease in mice.
		Interleukin (IL)-10 inhibits nuclear factor kappa B (NF kappa B) activation in human monocytes.
	jvi.asm.org /cgi/content/full/78/24/13697 (6289 words)

	interleukin.html
		TI: Fibronectin modulates interleukin 6 and fibronectin synthesis of human glomerular mesangial cells in culture.
		Because of their broad potential for modulation we examined the effect of a cytokine growth factor which is present constitutively in the marrow, interleukin 3 (IL3), on integrin-mediated adherence of hemopoietic progenitor cells to the matrix component fibronectin (FN).
		To study the role of this domain in adhesion, we have expressed in NIH 3T3 cells a cDNA consisting of the interleukin 2 receptor alpha subunit extracellular and transmembrane domains, connected to the integrin beta 1 cytoplasmic domain (IL2R-beta 1).
	www.indiana.edu /~pietsch/interleukin.html (14766 words)

	Melanoma Center - Types of Treatment - Biological Therapy - Immunotherapy - Interleukin-2
		Like interferons, interleukins are cytokines, naturally produced proteins of the immune system.
		One type, interleukin-2, causes the immune system's T-cells to multiply and perform a variety of functions, including killing cancer cells.
		High-dose recombinant interleukin 2 therapy for patients with metastatic melanoma: analysis of 270 patients treated between 1985 and 1993.
	www.melanomacenter.org /treatment/interleukin.html (319 words)

	Pathophysiological roles of interleukin-8/CXCL8 in pulmonary diseases -- Mukaida 284 (4): 566 -- AJP - Lung Cellular ...
		Detection of interleukin 8 and tumor necrosis factor in normal humans after intravenous endotoxin: the effect of antiinflammatory agents.
		Molecular cloning of a human monocyte-derived neutrophil chemotactic factor (MDNCF) and the induction of MDNCF mRNA by interleukin 1 and tumor necrosis factor.
		Inhibition of interleukin 8 attenuates angiogenesis in bronchogenic carcinoma.
	ajplung.physiology.org /cgi/content/full/284/4/L566 (7077 words)

	Recombinant Human Interleukin-3 - CYT-210
		Diphtheria toxin fused to variant human interleukin-3 induces cytotoxicity of blasts from patients with acute myeloid leukemia according to the level of interleukin-3 receptor expression.
		Recombinant human interleukin-3 administered concomitantly with chemotherapy in patients with relapsed small cell lung cancer.
		Evidence for a lectin activity for human interleukin 3 and modeling of its carbohydrate recognition domain.
	www.prospec.co.il /~prospec/cart/catalog/rHuIL3.html (463 words)

	CancerGuide: Nutritional Supplements and Interleukin-2
		Marcus SL, Petrylak DP, Dutcher JP, Paietta E, Ciobanu N, Strauman J, Wiernik PH, Hutner SH, Frank O, Baker H. Hypovitaminosis C in patients treated with high-dose interleukin 2 and lymphokine-activated killer cells.
		Marcus SL, Dutcher JP, Paietta E, Ciobanu N, Strauman J, Wiernik PH, Hutner SH, Frank O, Baker H. Severe hypovitaminosis C occurring as the result of adoptive immunotherapy with high-dose interleukin 2 and lymphokine-activated killer cells.
		Effects of interleukin 2 therapy on lymphocyte magnesium levels.
	www.cancerguide.org /rcc_il2supplements.html (1470 words)

	The Body: Interleukin
		Interleukin 2 and Immune Reconstitution (July 25, 2000)
		Interleukin 2 Treatment for HIV Infection (July 12, 2000)
		Immunologic and Virologic Effects of Subcutaneous Interleukin 2 in Combination With Antiretroviral Therapy: A Randomized Controlled Trial (July 12, 2000)
	www.thebody.com /treat/interleu.html (962 words)

	Arterial Inflammation in Mice Lacking the Interleukin 1 Receptor Antagonist Gene -- Nicklin et al. 191 (2): 303 -- The ...
		Arterial Inflammation in Mice Lacking the Interleukin 1 Receptor Antagonist Gene -- Nicklin et al.
		Arterial Inflammation in Mice Lacking the Interleukin 1 Receptor Antagonist Gene
		Interleukin 1 genetics, inflammatory mechanisms, and nutrigenetic opportunities to modulate diseases of aging
	www.jem.org /cgi/content/abstract/191/2/303 (1470 words)

	Interleukin
		Interleukin Genetics is among the world leaders in understanding and applying the genetics of inflammation, one of the body's most important defense mechanisms, to improve health.
		Our core mission is: (1) to develop genetic tests to inform people about increased risk for disease; and (2) to develop preventive and therapeutic products to reduce the risk of those diseases.
		Interleukin Genetics CEO to present at Korean Conference on Aging (5/16/06)
	www.ilgenetics.com (96 words)

	The soluble interleukin 6 receptor: mechanisms of production and implications in disease -- JONES et al. 15 (1): 43 -- ...
		INTERLEUKIN 6 (IL-6) IS produced by a variety of cell types
		Interleukin 6 signaling is facilitated through the homodimerization
		Interleukin 6 has been proposed to act as both a pro- and anti-inflammatory
	www.fasebj.org /cgi/content/full/15/1/43 (6829 words)

	NEJM -- The Role of Interleukin-1 in Disease
		Increased rectal mucosal expression of interleukin 1{beta} in recently acquired post-infectious irritable bowel syndrome.
		Association of the interleukin 1 receptor antagonist gene with ulcerative colitis in Northern European Caucasians.
		Five genetic markers in the interleukin 1 family in relation to inflammatory bowel disease.
	content.nejm.org /cgi/content/extract/328/2/106 (2287 words)

	Interleukin-1{beta} Enhances Interleukin-1 Receptor Antagonist Content in Human Somatotroph Adenoma Cell Cultures -- ...
		1990 Intrinsic pituitary interleukin 1-ß is induced by bacterial lipopolysaccharide.
		1993 Interleukin involvement in anterior pituitary cell growth regulation: effects of interleukin-2 (IL-2) and IL-6.
		1993 Interleukin 1 receptor antagonist inhibits the augmentation of metastasis induced by interleukin 1 or lipopolysaccharide in a human melanoma/nude mouse system.
	jcem.endojournals.org /cgi/content/full/83/7/2429 (4237 words)

	Polymorphisms Within the Interleukin-1{beta} Gene Cluster and Preeclampsia -- HEFLER et al. 97 (5): 664 -- Obstetrics & ...
		A new member of the interleukin 1 family.
		Interleukin 1 receptor antagonist is a member of the interleukin 1 gene family: Evolution of a cytokine control mechanism.
		Expression of the placental cytokines tumor necrosis factor alpha, interleukin 1beta, and interleukin 10 is increased in preeclampsia.
	www.greenjournal.org /cgi/content/full/97/5/664 (2221 words)

	Autoantibodies against interleukin 1{alpha} in rheumatoid arthritis: association with long term radiographic outcome -- ...
		Autoantibodies against interleukin 1{alpha} in rheumatoid arthritis: association with long term radiographic outcome -- Graudal et al.
		Abbreviations: aAb, autoantibodies; IL, interleukin; ra, receptor antagonist; RA, rheumatoid arthritis; TNF tumour necrosis factor
		A multicentre, double blind, randomised, placebo controlled trial of anakinra (Kineret), a recombinant interleukin 1 receptor antagonist, in patients with rheumatoid arthritis treated with background methotrexate
	ard.bmjjournals.com /cgi/content/abstract/61/7/598 (371 words)

	Inhibition of endotoxin-induced lung inflammation by interleukin-10 gene transfer in mice -- Dokka et al. 279 (5): 872 ...
		Interleukin (IL)-10 is an anti-inflammatory cytokine that has great potential for use in the treatment of inflammatory and
		Effect of pretreatment of mice with indicated amounts of recombinant interleukin (IL)-10 2 h before instillation of LPS (0.03 mg/mouse).
		Ghivizzani, SC, Lechman ER, Kang R, Tio C, Kolls J, Evans CH, and Robbins PD. Direct adenovirus-mediated gene transfer of interleukin 1 and tumor necrosis factor alpha soluble receptors to rabbit knees with experimental arthritis has local and distal anti-arthritic effects.
	ajplung.physiology.org /cgi/content/full/279/5/L872 (3677 words)

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