
	Where results make sense

Topic: International HapMap Project

Related Topics

Race

IQ and the Wealth of Nations

Scientific racism

The Bell Curve

Race

In the News (Fri 17 Feb 12)

EXECUTIVE POWER

Iran

ANALYSIS

Pakistan

Family compact

	National Human Genome Research Institute - Background on Ethical and Sampling Issues Raised by the International ...
		Members of the research consortium working on the International HapMap Project have taken steps to try to ensure that the map will be designed, developed and used in a manner that is sensitive to the ethical, legal and social concerns raised by this type of genomics research.
		The HapMap will describe the common patterns of human genetic variation and will be used in future studies that compare the patterns of genetic variation (haplotypes) in people with a specific disease to patterns in people who do not have the disease.
		When researchers use the HapMap and find that a disease is associated with a genetic variant that is common in a particular population, some people may mistakenly generalize that all individuals in that population have increased risk for the disease or that the population as a whole is somehow genetically inferior.
	www.genomica.net /RICERCA/HAPMAP/HAPMAP_etica.htm (1455 words)

	Technology Review: A New Genetic Globe (Site not responding. Last check: 2007-10-17)
		The International HapMap Project, launched in October 2002, has catalogued more than three million single-nucleotide polymorphisms (SNPs), or single-point differences in the sequence of the human genome, based on samples from four different populations around the world.
		The HapMap Consortium undertook the project in an effort to speed the identification of genes involved in common diseases, such as cancer and diabetes.
		HapMap by Guest (Tony Beals) 11/9/2005 1:27 PM If you are assuming that every disease (cancer, etc.) is gene related rather than lifestyle such as diet I believe that this study may be flawed.
	www.technologyreview.com /wtr_15860,1,p1.html?trk=nl (613 words)

	The Cancer Genome Atlas - International HapMap Project
		The HapMap should be valuable by reducing the number of SNPs required to examine the entire genome for association with a phenotype from the 10 million SNPs that exist to roughly 500,000 tag SNPs.
		In addition to its use in studying genetic associations with disease, the HapMap should be a powerful resource for studying the genetic factors contributing to variation in response to environmental factors, in susceptibility to infection, and in the effectiveness of and adverse responses to drugs and vaccines.
		All such studies will be based on the expectation that there will be higher frequencies of the contributing genetic components in a group of people with a disease or particular response to a drug, vaccine, pathogen, or environmental factor than in a group of similar people without the disease or response.
	cancergenome.nih.gov /related/ihp.asp (431 words)

	About the HapMap
		The International HapMap Project is a multi-country effort to identify and catalog genetic similarities and differences in human beings.
		The Project is a collaboration among scientists and funding agencies from Japan, the United Kingdom, Canada, China, Nigeria, and the United States.
		The goal of the International HapMap Project is to compare the genetic sequences of different individuals to identify chromosomal regions where genetic variants are shared.
	www.hapmap.org /thehapmap.html.en (241 words)

	International HapMap Project - Wikipedia, the free encyclopedia
		The International HapMap Project is an organization whose goal is to develop a haplotype map of the human genome (the HapMap), which will describe the common patterns of human genetic variation.
		The project is a collaboration among researchers at academic centers, non-profit biomedical research groups and private companies in Canada, China, Japan, Nigeria, the United Kingdom, and the United States.
		Four populations were selected for inclusion in the HapMap: 30 adult-and-both-parents trios from Ibadan, Nigeria (YRI), 30 trios of U.S. residents of northern and western European ancestry (CEU), 44 unrelated individuals from Tokyo, Japan (JPT) and 45 unrelated Han Chinese individuals from Beijing, China (CHB).
	en.wikipedia.org /wiki/International_HapMap_Project (936 words)

	News: International consortium completes most important genetic map since the Human Genome Project
		The International HapMap Consortiumwww.hapmap.org published a comprehensive catalogue of human genetic variation today, a landmark achievement that is already accelerating the search for genes involved in common diseases, such as asthma, diabetes, cancer and heart disease.
		The consortium is also nearing completion of the Phase II HapMap that will contain nearly three times as many markers as the initial version and will enable researchers to focus their gene searches even more precisely on specific regions of the genome.
		By using HapMap data to compare the SNP patterns of people affected by a disease with those of unaffected people, researchers can survey genetic variation across the whole genome and identify genetic contributions to common diseases far more efficiently than is possible with traditional approaches.
	www.admin.ox.ac.uk /po/news/2005-06/oct/27.shtml (869 words)

	Gene Expression: Ethics of the Hapmap
		The HapMap Project is a major international research effort to construct a resource to facilitate future studies that relate human genetic variation to health and disease.
		Project researchers will not seek patents on the data that they generate for which they have not demonstrated a specific use (such as relating a particular haplotype to a disease) and will not use the Project data for other projects in their laboratories before the data are released.
		Consistent with international guidelines stating that any knowledge generated from research that is done in a resource-poor country should be made reasonably available for the benefit of its people33, the HapMap Project data will be placed in the public domain and will be accessible to researchers around the globe.
	www.gnxp.com /MT2/archives/002343.html (8130 words)

	BBC NEWS \| Health \| Gene map points to personal drugs
		In the HapMap research, the vast majority of both rare and common genetic differences were found in all the populations studied.
		The HapMap emerged from the Human Genome Project that produced the first human genetic blueprint in 2003.
		Details of the HapMap project are being presented to a meeting of the American Society of Human Genetics this week.
	news.bbc.co.uk /1/hi/health/4378624.stm (675 words)

	International HapMap Consortium Widens Data Access, December 10, 2004 Press Release - National Institutes of Health ...
		The $130 million project, which was launched in October 2002 and is expected to be completed in September 2005, is a public-private partnership of scientists and funding agencies from Canada, China, Japan, Nigeria, the United Kingdom and the United States.
		However, concerns existed that outside groups might be able to combine some of the HapMap data with their own data to generate patentable inventions — a process referred to by some as "parasitic patenting." Such patents could potentially be used to exclude other researchers from being able to freely use the HapMap data.
		To prevent this from happening, the HapMap consortium required users to sign, using a simple mouse click from their computers, a free, non-exclusive, non-royalty-bearing licensing agreement to obtain access to certain types of data the project had collected on individuals' DNA sequences, specifically the genotypes.
	www.nih.gov /news/pr/dec2004/nhgri-10.htm (918 words)

	NIH Guide: LARGE-SCALE GENOTYPING FOR THE HAPLOTYPE MAP OF THE HUMAN GENOME
		The HapMap is expected to be valuable by reducing the number of SNPs required to examine the entire genome for association with a phenotype from 10 million SNPs to roughly 300,000 tag SNPs.
		In addition to its use in studying genetic associations with disease, the HapMap is expected to be a powerful resource for studying the genetic factors contributing to variation in response to environmental factors, in susceptibility to infection, in host immune responses, and in the effectiveness of and adverse responses to drugs and vaccines.
		Research Scope The goal of the HapMap Project is to develop a genome-wide haplotype map by identifying the haplotype blocks and the common haplotypes in the human genome, and to define a set of tag SNPs, using the population samples discussed above.
	grants.nih.gov /grants/guide/rfa-files/RFA-HG-02-005.html (6294 words)

	Data Release Policy
		The data being generated by the Project are the new SNPs identified, the genotypes of the 270 individual DNA samples for about 3 million SNPs, the frequencies of SNPs and haplotypes in each population, and the tag SNPs used to identify haplotypes.
		The participants in the Project believe that patents should not be issued for a SNP or haplotype for which a "specific utility" -- as defined in patent law -- has not been generated.
		Participants in the Project have agreed that they will not use HapMap data for other projects in their laboratories before the data are publicly released.
	hapmap.jst.go.jp /datareleasepolicy.html.en (261 words)

	Genome project Summary
		Genome projects are scientific endeavours that ultimately aim to determine the complete genome sequence of an organism (be it an animal, a plant, a fungus, a bacterium, an archaean, a protist or a virus).
		The Human Genome Project was a landmark genome project and some have argued that the era of genomics is one of the more fundamental advances in human history.
		Such projects may also include gene prediction to find out where the genes are in a genome, and what those genes do.
	www.bookrags.com /Genome_project (951 words)

	Illumina's BeadArray technology to underpin Canadian genotyping in HapMap Project
		Thomas Hudson, M.D., principal investigator and head of the Canadian HapMap Project team, commented: "Illumina's system enables a scale of experimentation and cost-effectiveness that is unmatched in the industry and consistent with what we need to execute our HapMap Project deliverables.
		The project will identify and map blocks of DNA into which the human genome is organised.
		Project contributors include research groups representing Canada, China, Japan, Nigeria, the United Kingdom, and the United States.
	www.hoise.com /vmw/03/articles/vmw/LV-VM-02-03-25.html (778 words)

	Wellcome Trust Sanger Institute Press Releases
		From its beginning, the consortium has made most of the results of the HapMap Project available to the scientific community and to the public quickly and freely on the Internet, in keeping with the data release approach established by the Human Genome Project.
		The consortium was concerned that other groups might combine some of the HapMap data on individual genotypes with their own data to generate patentable inventions on haplotypes and then use these patents to exclude researchers from being able to use the HapMap data, which some call 'parasitic' patents.
		Researchers are already using the HapMap data to study conditions such as type 2 diabetes, asthma and dyslexia, as well as genes related to drug metabolism and adverse effects.
	www.sanger.ac.uk /Info/Press/2004/041213.shtml (863 words)

	Wellcome Trust Sanger Institute Press Releases
		International HapMap Consortium, to which The Wellcome Trust is a major contributor, describes important new tools it will produce to enhance our use of the human genome sequence and to fast-track that quest.
		The HapMap Project will define those all-important 'tag' SNPs in multiple populations and the regions of the genome where they are located.
		As a result of the HapMap Project, researchers will not have to search through the 10,000,000 SNPs that occur in the human genome, but instead will be able to use the map developed by the Project to obtain as much information using a massively reduced number of SNPs, about 500,000.
	www.sanger.ac.uk /Info/Press/2003/031218.shtml (1154 words)

	NIH Guide: ADDITIONAL GENOTYPING FOR THE HUMAN HAPLOTYPE MAP
		The International HapMap Consortium is a collaboration among researchers in six countries: Japan, the United Kingdom, Canada, China, Nigeria, and the U.S. An earlier RFA (http://grants.nih.gov/grants/guide/rfa-files/RFA-HG-02-005.html) solicited research proposals for genotyping SNPs in the chromosomes that are to be done by U.S. researchers for the Project, which is almost one-third of the genome.
		The NHGRI thus has adopted the International HapMap Consortium’s policies and procedures for data submission and release, which were designed to ensure the access of researchers to the HapMap data (Nature 426: 789-796 (2003), http://www.hapmap.org/downloads/datarelease.html, http://www.hapmap.org/cgi-perl/registration).
		The International HapMap Consortium members have also agreed that their own laboratories will access the data only through the DCC and under the license terms, to ensure that all scientists have equal access to the data for research in which the HapMap is used.
	grants.nih.gov /grants/guide/rfa-files/RFA-HG-04-005.html (6410 words)

	Project to Identify Genes For Common Illnesses Launched - 2002-11-01 (Site not responding. Last check: 2007-10-17)
		Researchers from around the world have launched a three-year project aimed at identifying genes that are responsible for such common illnesses as cancer, heart disease and diabetes.
		The $100-million International HapMap Project, described as the next phase of the Human Genome Project, is a refinement.
		The HapMap project is scheduled to take three years to complete, although researchers hope to finish it sooner.
	www.voanews.com /english/archive/2002-11/a-2002-11-01-14-Project.cfm (711 words)

	ScienceDaily: International Consortium Launches Genetic Variation Mapping Project; Hapmap Will Help Identify Genetic ...
		Called the International HapMap Project, this new venture is aimed at speeding the discovery of genes related to common illnesses such as asthma, cancer, diabetes and heart disease.
		For this reason, the HapMap consortium needs to include samples from a few geographically separated populations to find the SNP variants that are common in any of the populations.
		In addition to its pioneering approach towards developing the HapMap and related technologies, the international consortium continues the strategy of pulling together a wide range of public and private partners from around the globe to both conduct and fund the research.
	www.sciencedaily.com /releases/2002/10/021031075131.htm (2211 words)

	HK Scientists to Join Int' HapMap Project
		The goal of the project is to develop a haplotype map of the human genome, describing the common patterns of human DNA sequence variants and to make this information freely available in the public domain.
		The HapMap is expected to be a key resource for researchers to use in finding genes that affect health, disease, and responses to drugs and environmental factor, Tsui said Thursday.
		The international HapMap project is a collaboration among scientists in the United States, the United Kingdom, Japan, Canada, China (including Hong Kong and Taiwan), and Nigeria.
	www.china.org.cn /english/scitech/82866.htm (389 words)

	Geneticists map what makes us different - The Boston Globe
		An international team of scientists announced yesterday that it has completed an ambitious map of all the common variations in the human genetic code, an advance that could accelerate the search for the genes behind a wide range of diseases.
		The HapMap, which is described in today's issue of the journal Nature, is a follow-up to the Human Genome Project, and an attempt to make it more useful for medical research.
		The HapMap project, which was funded by an international consortium that includes the US government, has located some 3.8 million of these tags, the scientists said.
	www.boston.com /news/nation/articles/2005/10/27/geneticists_map_what_makes_us_different (1473 words)

	International HapMap Consortium publishes scientific strategy
		The $120 million International HapMap Project was launched in October 2002 and is expected to take three years to complete.
		The project is a partnership of scientists and funding agencies from Canada, China, Japan, Nigeria, the United Kingdom and the United States.
		In addition to the current paper detailing the project's scientific strategy, the consortium plans to publish a companion paper describing in more detail how the project is addressing the ethical, social and cultural concerns raised by this type of genomics research.
	www.eurekalert.org /pub_releases/2003-12/nhgr-ihc121603.php (354 words)

	Biocompare News - International HapMap Consortium Publishes Scientific Strategy
		The project is a partnership of scientists and funding agencies from Canada, China, Japan, Nigeria, the United Kingdom and the United States.
		The U.S. component of the International HapMap Project is led by the National Human Genome Research Institute (NHGRI), which is part of the National Institutes of Health, an agency of the Department of Health and Human Services.
		In addition to the current paper detailing the project's scientific strategy, the consortium plans to publish a companion paper describing in more detail how the project is addressing the ethical, social and cultural concerns raised by this type of genomics research.
	news.biocompare.com /newsstory.asp?id=22268 (386 words)

	Washington University SNP Research - Articles - HapMap Project and Personalized Medicine
		It marks the conclusion of the first phase of the International HapMap Project - a five-year sequel to the Human Genome Project that began in 2001.
		The project's goal was to identify the patterns of human genetic variation using single-nucleotide polymorphisms (SNPs).
		Before the HapMap Project, choosing the best SNPs for an association study was an extraordinarily difficult problem.
	snp.wustl.edu /articles/hapmap-personalized-medicine.html (499 words)

	Technology Review: A New Genetic Globe
		The International HapMap Project, launched in October 2002, has catalogued more than three million single-nucleotide polymorphisms (SNPs), or single-point differences in the sequence of the human genome, based on samples from four different populations around the world.
		The HapMap Consortium undertook the project in an effort to speed the identification of genes involved in common diseases, such as cancer and diabetes.
		HapMap by Guest (Tony Beals) 11/9/2005 1:27 PM If you are assuming that every disease (cancer, etc.) is gene related rather than lifestyle such as diet I believe that this study may be flawed.
	www.techreview.com /Biotech/15860 (679 words)

Try your search on: Qwika (all wikis)