| |
| | Zyprexa (Olanzapine) IntraMuscular Rapidly Controls Acute Agitation in Bipolar Mania |
 | | To date in the United States, there are no drugs, either in an oral or intramuscular formulation, specifically approved by the Food and Drug Administration for the treatment of acute agitation in patients with bipolar mania. |
 | | After a screening period, 201 patients were randomly allocated to treatment with either the atypical antipsychotic Zyprexa Intramuscular, intramuscular lorazepam, or intramuscular placebo. |
 | | Patients received from one to three intramuscular injections based on the clinical judgment of the investigator: Zyprexa (10 mg, first two injections; 5 mg, third injection); lorazepam (2 mg, first two injections; 1 mg, third injection); or placebo (placebo, first two injections; Zyprexa 10 mg, third injection) within a 24-hour period. |
| www.docguide.com /dg.nsf/PrintPrint/2DB3AC4D87AB791785256A9C0053B720 (901 words) |
|