| | Intracellular Ion Environment and Membrane Electric Potential |
 | | The movement of ions across the plasma membrane and organelle membranes is mediated by several types of transport proteins: all symporters and certain antiporters cotransport ions simultaneously along with specific small molecules, whereas ion channels, ion pumps, and some antiporters transport only ions. |
 | | In all cases, the rate and extent of ion transport across membranes is influenced not only by the ion concentrations on the two sides of the membrane but also by the voltage (i.e., the electric potential) that exists across the membrane. |
 | | However, continued right-to-left movement of the Na ions eventually is inhibited by the mutual repulsion between the excess positive (Na) charges accumulated on the left side of the membrane and by the attraction of Na ions to the excess negative charges built up on the right side. |
| www.ncbi.nlm.nih.gov /books/bv.fcgi?rid=mcb.section.4055 (2011 words) |