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| | 477. Ionone, beta- (WHO Food Additives Series 14) |
 | | No adverse effects were observed as judged (in comparison with controls) by appearance, growth, haematological and blood chemical determinations, terminal body weight, organ weights, or gross and microscopic examination of major organs (Oser et al., 1965). |
 | | Groups of 10 male and 10 female rats were maintained for 17 weeks on diets containing "Ionone Standard" (60% alpha-ionone and 40% ß-ionone) at levels of 0, 1000, 2500, and 10 000 ppm (approximately equivalent to 50, 125, and 500 mg/kg bw). |
 | | No adverse effects were observed on growth, appearance, food intake, haematology, final body weights, organ weights, or macroscopic appearance of organs of rats on all levels of "Ionone Standard" in the diet. |
| www.inchem.org /documents/jecfa/jecmono/v14je13.htm (770 words) |
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