| | Dry Powder Ipratropium Bromide Is As Safe and Effective As Metered-Dose Inhaler Formulation: A Cumulative Dose-Response ... (Site not responding. Last check: ) |
 | | Ipratropium bromide is a quaternary ammonium anticholinergic compound chemically related to atropine. |
 | | The bronchodilator action of ipratropium bromide is dose-dependent, and the recommended dose is not a definite dose but rather a range of doses, depending on the subject, the disease, and the severity of the disease. |
 | | Earlier powder inhalation formulations of ipratropium bromide used anhydrous glucose as the carrier substance, but the rate and extent of water uptake is less with lactose than with glucose, so the lactose-excipient DPI is less sensitive to environmental humidity than glucose-excipient DPI. |
| www.rcjournal.com /contents/02.02/02.02.0159.asp (796 words) |