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Topic: Iron poisoning


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In the News (Sat 28 Nov 09)

  
  Iron poisoning - Wikipedia, the free encyclopedia
Iron poisoning is caused by an excess of iron in the blood.
In nature, iron is usually found in its oxidized form, iron (III) oxide, which is insoluble and therefore non-toxic.
The first indication of iron poisoning by ingestion is a pain in the stomach, as the stomach lining becomes ulcerated.
en.wikipedia.org /wiki/Iron_poisoning   (188 words)

  
 CPCS: Iron Poisoning
Iron is important for good nutrition because it is used in blood and muscle tissue.
Iron is available in numerous over-the-counter and prescription tablets and liquids, such as ferrous sulfate, ferrous gluconate and ferrous fumarate.
Treatment for iron poisoning may include removing iron from the stomach, checking a blood level and, when needed, giving a chelating agent to bind up the iron in the bloodstream and help eliminate it from the body.
www.calpoison.org /public/iron.html   (491 words)

  
 Iron
Iron plays a role in the creation of chlorophyll in plants and is an essential part of hemoglobin, the substance that carries oxygen within red blood cells.
Iron ore is the term applied to a natural iron-bearing mineral in which the content of iron is sufficient to be commercially usable.
Iron cannot be excreted therefore the excess builds to toxic levels in tissues of major organs such as the liver, heart, pituitary, thyroid, pancreas, lungs, and synovium (joints).
www.heavymetalstest.com /iron.php   (990 words)

  
 CPCS: Call Us!... Newsletter (Feb 2002)
Multisystem failure from iron poisoning results from cell death and tissue necrosis secondary to injury to the GI mucosa, the liver and the lung.
Iron poisoning should be considered in any patient with GI symptoms, mental status changes, and an unexplained anion-gap metabolic acidosis.
Total iron binding capacity (TIBC) is listed in many sources as a useful laboratory parameter to evaluate the severity of iron toxicity; however, controlled studies have shown TIBC to be an unreliable laboratory index of iron poisoning.
www.calpoison.org /hcp/Cal_us_archives/call_us_feb03.html   (2230 words)

  
 FDA/CFSAN FDA Backgrounder: Preventing Iron Poisoning in Children
Accidental iron overdose is a leading cause of poisoning deaths in children under 6 in the United States.
Some iron products are available without a prescription, either as single-ingredient iron pills, which may contain 30 mg or more of iron per dose, or in combination with vitamins or other minerals--for example, pediatric vitamins with iron--which often have less than 30 mg of iron per dose.
The proposal came in recognition of a recent upsurge in iron poisoning cases among children and in response to three citizen petitions submitted to FDA by the American Association of Poison Control Centers, the attorneys general of 34 states, and the Nonprescription Drug Manufacturers Association.
vm.cfsan.fda.gov /~dms/bgiron.html   (1391 words)

  
 Indian Pediatrics - Editorial
Another drawback with use of serum iron as a guide to therapy is that the report of serum iron should be available immediately to enable a timely therapeutic decision-making, which is not feasible in most of health care facilities in our country.
Efficacy of orally administered iron chelator deferiprone in acute iron poisoning is still under investigation though findings from experimental studies in animals hold promise for its use in humans(19).
The efficacy of oral deferiprone in acute iron poisoning.
www.indianpediatrics.net /june2003/june-534-540.htm   (2708 words)

  
 Iron tests
Iron tests are a group of blood tests that are done to evaluate the iron level in blood serum, the body's capacity to absorb iron, and the amount of iron actually stored in the body.
Iron is an essential trace element; it is necessary for the formation of red blood cells and certain enzymes.
The iron level test measures the amount of iron in the blood serum that is being carried by a protein (transferrin) in the blood plasma.
www.healthatoz.com /healthatoz/Atoz/ency/iron_tests.jsp   (1171 words)

  
 WHFoods: iron
Iron serves as the core of the hemoglobin molecule, which is the oxygen-carrying component of the red blood cell.
Iron poisoning, caused by acute ingestion of large quantities of iron-containing supplements, causes nausea, vomiting, damage to the lining of the intestinal tract, shock, and liver failure, and is a leading cause of death among children.
Iron absorption is increased when there is an increased physiological need for iron, as occurs in children during rapid growth periods and during pregnancy and lactation.
www.whfoods.com /genpage.php?tname=nutrient&dbid=70   (1573 words)

  
 IRON
Iron is an essential element in the body, needed to make the oxygen carrying protein of the red blood cells, haemoglobin (see the 'metals in nutrition section' on iron).
Iron in these tablets is in the form of salts, and may be ingested in suicide attempts or by small children.
Once excess iron has been ingested, the body has no natural means of getting rid of it so it continues to store it, as it would do with iron that is ingested in normal circumstances through the diet.
www.portfolio.mvm.ed.ac.uk /studentwebs/session2/group29/irontox.htm   (1025 words)

  
 Iron Poisoning | Poison Control Center - Children's Hospital of Philadelphia
Iron is available as ferrous sulfate (20 percent elemental iron), ferrous fumarate (33 percent elemental iron) and ferrous gluconate (12 percent elemental iron) salts, as prenatal vitamins and in multivitamin preparations.
Acute iron poisoning produces gastrointestinal, cardiovascular, metabolic, hepatic, and central nervous system effects secondary to both the direct caustic effect of iron on the GI mucosa and to the presence of free unbound iron in the circulation.
Iron tablets are radiopaque, therefore, an abdominal radiograph should be performed to determine if there is evidence of iron tablets in the stomach or small bowel.
www.chop.edu /consumer/jsp/division/generic.jsp?id=72615   (853 words)

  
 eMedicine - Toxicity, Iron : Article by Clifford Spanierman, MD
Iron is used as a pediatric or prenatal vitamin supplement and for treatment of anemia.
Hepatic dysfunction is common in severe iron poisoning because the liver is the first organ outside of the GI tract to encounter iron.
Approximately 8 mg of iron is bound by 100 mg of deferoxamine.
www.emedicine.com /emerg/topic285.htm   (2100 words)

  
 Iron Poisoning
Iron poisoning occurs when a person, usually a child, swallows a large number of iron-containing pills, most often vitamins.
Acute iron poisoning mainly involves children younger than 6 years who swallow pediatric or adult vitamins containing iron.
Iron preparations are widely used and are available without a prescription and may be housed in bottles with or without child resistant closures.
www.emedicinehealth.com /iron_poisoning/article_em.htm   (278 words)

  
 Iron
Iron is mainly absorbed in the duodenum and upper jejunum.
Most of the iron in the body is recycled when old red blood cells are taken out of circulation and destroyed, with their iron scavenged by macrophages in the mononuclear phagocyte system, and returned to the storage pool for re-use.
The probable defect is a cytokine-mediated blockage in transfer of iron from the storage pool to the erythroid precursors in the bone marrow.
www-medlib.med.utah.edu /WebPath/TUTORIAL/IRON/IRON.html   (2119 words)

  
 CNN Food Central - Resources: Iron Quick Facts
Children with iron poisoning may immediately suffer nausea, vomiting, diarrhea, and intestinal hemorrhaging, leading to coma and death.
In addition, some people suffer from hemochromatosis, also known as "iron overload disease." Iron overload patients do not process iron properly; instead, excess iron is stored in their organs, where it eventually causes heart and liver disease and other problems.
Iron sources that have high iron availability include oysters, liver and other organ meats, lean red meat, tuna, and eggs (especially egg yolks).
www.cnn.com /FOOD/resources/food.for.thought/explainers/iron.facts.html   (432 words)

  
 New center treats victims of chronic iron poisoning
Iron is needed to develop blood cells that promote growth and help the body fight infection.
But while the average person eventually excretes most of the iron he consumes through the bowels, the kidneys, the skin and the hair, those with hemochromatosis absorb iron, storing it in their organs.
Iron overload can be detected through blood samples and DNA testing, which involves collecting tissue from the inside of the cheek with a tiny brush.
www.post-gazette.com /healthscience/19981110hemo1.asp   (1395 words)

  
 Pediatric Iron Poisoning
Please note that iron absorption may be prolonged or delayed, owing to the formation of bezoars (a concretion of tablets) or ingestion of sustained-release preparations.
Multiple serum iron concentrations are necessary to adequately manage serious iron poisoning cases.

For many years, measurement of total iron binding capacity (TIBC) was suggested along with the serum iron measurement as a method of identifying the specific individualandapos;s ability to bind iron.

In moderate to severe iron poisoning, the risk of not treating will outweigh any potential teratogenic risk to the fetus, and deferoxamine should not be withheld.

In patients with iron-induced injury to the GI tract, treatment with deferoxamine, particularly by the oral route, may predispose them to sepsis with Yersinia enterocolitica.

www.medscape.com /content/2000/00/40/85/408556/408556.xml   (1855 words)

  
 Iron Poisoning: Poisoning: Merck Manual Home Edition
The symptoms of iron poisoning typically occur in four stages.
The diagnosis of iron poisoning is based on the person's history, symptoms, and the amount of iron in the blood.
To remove any iron remaining in the stomach, gastric lavage may be necessary.
www.merck.com /mrkshared/mmanual_home2/sec24/ch297/ch297h.jsp   (401 words)

  
 EMSA Online - Lead and Iron Poisoning
However, iron is an essential nutrient sometimes lacking in people’s diets which is why iron is often recommended for people with conditions such as iron-deficiency anemia.
Even if a child appears to have no symptoms after accidentally swallowing iron, or appears to be recovering, medical evaluation should still be sought since successful treatment is difficult once iron is absorbed from the small intestine into the bloodstream.
And children who survive iron poisoning can experience other problems, such as gastrointestinal obstruction and liver damage, up to four weeks after the ingested poisoning.
www.emsaonline.com /mediacenter/articles/00000051.html   (299 words)

  
 Preventing Childhood Poisoning (FDA Consumer Reprint)
Childhood poisonings caused by accidental overdoses of iron-containing supplements are the biggest concern of poison control experts, consumer protection groups, and health-care providers.
Iron is always included in prenatal vitamins prescribed for pregnant women, and is often included in multivitamin formulas and children's supplements.
The nation's first poison control center opened in Chicago in 1953, after a study of accidental deaths in childhood reported a large number were due to poisoning.
www.fda.gov /fdac/features/296_kid.html   (3290 words)

  
 Preventing Childhood Poisoning
Iron is an essential nutrient sometimes lacking in people's diets, which is why iron is often recommended for people with conditions such as iron-deficiency anemia.
Iron products are regulated as drugs if they are intended to affect the structure or function of the body, or are used in the diagnosis, cure, treatment, or prevention of disease and are listed in the U.S. Pharmacopeia.
Iron is always included in prenatal vitamins prescribed for pregnant women, and is sometimes included in multivitamin formulas.
www.kidsource.com /kidsource/content3/fda.poisoning.all.safety.html   (3352 words)

  
 Medical/cast iron poisoning   (Site not responding. Last check: 2007-10-25)
This is presented in two halves: first, implications of iron in arthritis, then the possibility of iron from cast-iron frying pans.
Stainless is readily attacked by organic acids, particularly at cooking temperatures; hence iron, chromium, and nickel should be released from the material into the food.
Daily dietary intake could vary from 11 to 6 mg of iron, 11 to 9 mg of zinc, 2 to 1 mg of copper and 0.4 to 0.1 mg of lead, depending on the cooking utensils used.
tafkac.org /medical/cast_iron_poisoning.html   (543 words)

  
 FDA Consumer: Preventive Measures Proposed for Childhood Iron Poisoning   (Site not responding. Last check: 2007-10-25)
To prevent accidental, potentially fatal childhood poisonings, FDA is proposing that packages of capsules and tablets containing iron be labeled with warnings.
Most prenatal iron products contain 30 mg or more of iron and are likely to be in homes with young children.
Accidental ingestion of iron is the leading cause of poisoning deaths in children under 6, despite child-resistant packaging.
vm.cfsan.fda.gov /~dms/fdupiron.html   (235 words)

  
 Iron Poisoning: Poisoning: Merck Manual Home Edition
Iron also is included in many multiple vitamin supplements.
Because many households contain multiple vitamin supplements for adults that contain iron, iron overdose is common.
If poisoning is very serious, rapid breathing, a rapid heart rate, and low blood pressure may develop.
www.merck.com /mmhe/print/sec24/ch297/ch297h.html   (394 words)

  
 CNN: In-Depth Food - Iron Facts
When adults take iron supplements following the directions on the label, the supplements are generally safe.
However, they can often raise their blood iron levels by eating more high-iron foods.
Commercial fl or pekoe teas also contain substances that bind to iron so it cannot be used by the body.
www.cnn.com /HEALTH/indepth.food/explainers/iron.facts.html   (424 words)

  
 Iron-Chelating Agents in Non-Iron Overload Conditions -- Voest et al. 120 (6): 490 -- Annals of Internal Medicine
Iron is an essential element for the proliferation of cells.
The role of iron in the pathogenesis of chronic doxorubicin induced cardio- and nephrotoxicity.
Iron metabolism in patients with the anaemia of end-stage renal disease during treatment with recombinant human erythropoietin.
www.annals.org /cgi/content/full/120/6/490   (6281 words)

  
 Iron Disorders Institute - Acquired Iron Overload
One can accumulate dangerously high levels of iron by accidental ingestion which usual occurs with young children who get iron pills prescribed for their mothers; these children can get very sick and can even die from iron poisoning.
The Centers for Disease Control and Prevention (CDC) states that accidental iron poisoning is one of the leading causes of poisoning in children.
In the case of accidental iron poisoning: contact your state poison control center and physician immediately.
www.irondisorders.org /Disorders/Acquired.asp   (381 words)

  
 33496. Iron Poisoning question [Utah]
It was almost 12 months before I could convince my heart doctor to refer me to a toxicologist after some research (msds) I have discovered that iron salts are very dangerous and can be absorbed into the skin.
If you were diagnosed with secondary polycythemia, exposure to iron salts is not listed as one of the causes.
As far as whether ferric chloride solution could be causing you medical problems, it would probably be best to get medical advice from an expert.
www.finishing.com /334/96.shtml   (469 words)

  
 Iron Toxicity in Children
Almost 17% of children's deaths reported to poison control centers between 1988 and 1992 were due to iron poisoning, compared to 12% between 1984 and 1987.
Supplements involved in the poisonings range from non-prescription daily multivitamin/mineral pills for children to prescription iron for pregnant women.
Caregivers of children need to be educated and/or reminded about the importance of keeping iron supplements out of the reach of children.
www.colostate.edu /Orgs/safefood/NEWSLTR/v2n3s04.html   (396 words)

  
 Wrong diagnosis of Iron poisoning - WrongDiagnosis.com
The other diseases for which Iron poisoning is listed as a possible alternative diagnosis in their lists include:
About misdiagnosis: When checking for a misdiagnosis of Iron poisoning or confirming a diagnosis of Iron poisoning, it is useful to consider what other medical conditions might be possible misdiagnoses or other alternative conditions relevant to diagnosis.
These alternate diagnoses of Iron poisoning may already have been considered by your doctor or may need to be considered as possible alternative diagnoses or candidates for misdiagnosis of Iron poisoning.
www.wrongdiagnosis.com /i/iron_poisoning/misdiag.htm   (207 words)

  
 Iron poisoning - WrongDiagnosis.com
What reseach is being conducted on Iron poisoning
Poisoning from overdose of iron (usually iron supplements)
Visit our research pages for current research about Iron poisoning treatments.
www.wrongdiagnosis.com /i/iron_poisoning/intro.htm   (200 words)

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