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Topic: Ischemia

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	Silent Ischemia - Texas Heart Institute Heart Information Center
		Ischemia is a condition where the flow of oxygen-rich blood to a part of the body is restricted.
		Cardiac ischemia refers to lack of blood flow and oxygen to the heart muscle.
		If ischemia is severe or lasts too long, it can cause a heart attack (myocardial infarction) and can lead to heart tissue death.
	www.tmc.edu /thi/silent.html (570 words)

	INTESTINAL ISCHEMIA - Patients - American College of Gastroenterology
		Intestinal ischemia is the term used to describe the result of a variety of disorders all of which ultimately reflect a state of insufficient blood flow to the small intestine, the colon, or both -- collectively referred to as the intestines.
		The injury and prognosis for any given episode of intestinal ischemia depend on the cause of the injury, the blood vessel(s) involved, the underlying medical condition of the patient, and the swiftness with which the problem is brought to medical attention for diagnosis and treatment.
		The most common cause of ischemia from venous obstruction is a thrombus which, as it interferes with return of blood flow from the intestines, produces intestinal congestion, and resulting intestinal swelling and thickening, as well as bleeding.
	www.acg.gi.org /patients/gihealth/ischemia.asp (2419 words)

	ISCHEMIA AND REPERFUSION INJURY IN CRYONICS
		Ischemia is the condition suffered by tissues and organs when deprived of blood flow -- mostly the effects of inadequate nutrient and oxygen.
		Ischemia in tissues and blood vessels results in large amounts of ATP being broken-down to xanthine.
		The longer the ischemia, the worse is the reperfusion injury to blood vessels due to free-radicals and hemorrhage -- and the greater the chance of "no reflow" (impeded circulation).
	www.benbest.com /cryonics/ischemia.html (5381 words)

	eMedicine - Myocardial Ischemia : Article by Michael E Zevitz, MD
		Ischemia may manifest as (1) anginal discomfort, (2) ST-segment deviation on ECG, (3) reduced uptake of thallium 201 or technetium 99 in myocardial perfusion images, or (4) regional or global impairment of ventricular function.
		Silent myocardial ischemia is indicated by lack of symptoms in the presence of documented ECG or nuclear imaging evidence of myocardial ischemia.
		Current understanding of myocardial ischemia suggests that the favored management approach is to appropriately and aggressively pursue all causes of myocardial ischemia and to appropriately treat all reversible causes until clinical and/or perfusion studies confirm that the myocardial ischemia is maximally reduced or eliminated.
	www.emedicine.com /med/topic1568.htm (12833 words)

	Ischemia (Site not responding. Last check: 2007-11-07)
		Ischemia is an insufficient supply of blood to an organ, usually due to a blocked artery.
		Ischemia is almost always caused by blockage of an artery, usually due to atherosclerotic plaque.
		Myocardial ischemia is also caused by blood clots (which tend to form on plaque), artery spasms or contractions, or any of these factors combined.
	www.healthatoz.com /healthatoz/Atoz/ency/ischemia.jsp (2693 words)

	Effects of pharmacotherapy and training on recovery after cerebral ischemia in rats
		The validity of these cerebral ischemia models is highly dependent on the strict control of physiological variables, such as body temperature, blood pressure, blood gases and glucose levels, which may fluctuate and lead to variability in the results (Ginsberg and Busto 1998; Hossmann 1998).
		In focal ischemia studies, the animals were decapitated and the brain were rapidly removed from the skull and frozen on dry ice.
		The rats having focal ischemia lesion showed the most rapid improvement in the beam-walking task, but ischemic rats were found to be inferior to sham-operated rats during the first 2 days of testing on days 2 and 3 after ischemia induction.
	www.uku.fi /neuro/58the.htm (17250 words)

	Prostatitis and Sitting Ischemia
		Because multiple causes leading to bladder ischemia also decrease urethral perfusion, we assessed the effect of in vitro ischemia on the contractile responses of the rat bladder and urethra.
		Ischemia 60 minutes in duration caused a significant decrease in the maximal rate of tension generated as well as maximal tension in the urethra and bladder but only in response to field stimulation.
		Ischemia induced glandular atrophy was consistently associated with decreased vascular endothelial growth factor expression.
	www.chronicprostatitis.com /sitting.html (1602 words)

	Intestinal ischemia
		Intestinal ischemia due to mesenteric venous thrombosis is caused by a blood clot blocking a vein in the intestines.
		Risk factors for ischemia due to mesenteric venous thrombosis are similar to those for deep vein thrombosis and can include long periods of inactivity — such as after surgery — obesity, certain types of cancer, birth control pills, smoking, and a history of high blood pressure or heart disease.
		If your doctor suspects intestinal ischemia, he or she may want to conduct a thorough medical evaluation because signs and symptoms of intestinal ischemia can be similar to those of other disorders, such as ulcers, as well as stomach, pancreatic or colon cancer.
	www.cnn.com /HEALTH/library/DS/00459.html (1974 words)

	VascularWeb: Mesenteric Ischemia
		Ischemia occurs when your blood cannot flow through your arteries as well as it should, and your intestines do not receive the necessary oxygen to perform normally.
		The goal of treatment for mesenteric ischemia (both chronic and acute) is to re-open the artery to allow adequate blood flow to reach your intestine to allow it to work properly.
		For chronic mesenteric ischemia, one treatment method is trans-aortic endarterectomy, which is an operation that removes the plaque that blocks your mesenteric artery.
	www.vascularweb.org /_CONTRIBUTION_PAGES/Patient_Information/NorthPoint/Mesenteric_Ischemia.html (1403 words)

	Re: Why do you feel the prickly feeling after releasing pressure on a nerve
		Ischemia is about the worst thing that can happen to a body part.
		The reason that ischemia causes paraesthesia is that eliminating a nerve's blood supply changes the excitability of the nerve.
		As the ischemia continues, the nerve steadily becomes less excitable, until finally it is unable to fire at all.
	www.madsci.org /posts/archives/dec96/850996021.Ns.r.html (1345 words)

	Mesenteric Ischemia (Site not responding. Last check: 2007-11-07)
		Acute ischemia must be treated with surgery within hours or the intestines, and possibly the patient, will die.
		If the ischemia was acute, there may be segments of intestine that are dead and need to be removed during the operation.
		In the future, using this research, we plan to use a SQUID device to diagnose mesenteric ischemia and to decide whether segments of the intestines are alive or dead.
	www.vanderbilt.edu /biomag/mesich.htm (685 words)

	Cardiac Ischemia Recovery & Prevention
		Ischemia (is-KE' me-ah) is a condition that occurs when blood flow and oxygen are kept from a particular part of the body.
		Cardiac ischemia is the name for this condition when the heart is the body part targeted.
		Ischemia is often the cause of chest pain known as angina pectoris (AN' jih-nah or an-JI' nah PEK' tor-is).
	www.cardiacischemia.com (357 words)

	ASM 15(4): Reconstruction for Limb Ischemia
		Gintaras Zukauskas, MD, PhD; Henrikas Ulevicius, MD Treatment of critical limb ischemia (CLI) remains one of the most demanding problems of vascular surgery, especially when it is due to multisegmental occlusive arterial disease.
		Multilevel disease most often manifests as severe ischemia and is described as Grade III and IV according to the Fountain classification.
		In most cases, when the patient presented with ischemia of the limb due to graft thrombosis, an operation to restore the blood flow was attempted.
	www.kfshrc.edu.sa /annals/154/94128/94128.html (3245 words)

	Endocytic Pathway Alterations in Human Hippocampus after Global Ischemia and the Influence of APOE Genotype -- McColl ...
		In contrast, after global ischemia, there is intense rabaptin-5 and rab4 immunoreactivity in the cytoplasm of neurons.
		There was a significant increase in the level of neuronal rabaptin-5 immunoreactivity after global ischemia compared with controls in all regions examined except the dentate gyrus.
		ischemia caused by cardiac arrest with subsequent cerebral reperfusion.
	ajp.amjpathol.org /cgi/content/full/162/1/273 (4952 words)

	Ischemic Preconditioning Attenuates Apoptotic Cell Death in the Rat Retina -- Zhang et al. 43 (9): 3059 -- ...
		For ischemia, the IOP was increased to 110 mm Hg by elevating the saline reservoir to sufficient height above
		Ischemia for 8 minutes was used as a preconditioning stimulus.
		The ERG a- and b-waves were normalized to the preischemia baseline and corrected for day-to-day variation with the data from the nonischemic control eye.
	www.iovs.org /cgi/content/full/43/9/3059 (4382 words)

	eMedicine - Mesenteric Ischemia : Article by Christopher MB Fernandes, MD (Site not responding. Last check: 2007-11-07)
		Fifty percent of acute mesenteric ischemia (AMI) cases are due to a superior mesenteric artery occlusion from a thrombus or an embolus; 25% of cases are due to a nonocclusive infarction; and the remainder of cases are due to an inferior mesenteric artery occlusion, a mesenteric venous thrombosis, or arteritis.
		The sine qua non of mesenteric ischemia is a relatively normal abdominal examination in the face of severe abdominal pain.
		Ruotolo RA, Evans SR: Mesenteric ischemia in the elderly.
	www.emedicine.com /emerg/topic311.htm (2052 words)

	Mitogen-Activated Protein Kinases and Retinal Ischemia -- Roth et al. 44 (12): 5383 -- Investigative Ophthalmology & ...
		There was a significant reduction in overall or inner retinal thickness after ischemia in the vehicle treated group and in the groups treated with either JNK inhibitor.
		The effect of inhibitors on phosphorylation of the JNK substrate c-Jun and the p38 substrate ATF-2 was studied after ischemia in 10-µm retinal cryosections stained with the peroxidase (DAB) reaction.
		Apoptotic DNA fragmentation and upregulation of Bax induced by transient ischemia of the rat retina.
	www.iovs.org /cgi/content/full/44/12/5383 (5879 words)

	Ischemia-Reperfusion-induced Lung Injury -- de Perrot et al. 167 (4): 490 -- American Journal of Respiratory and ...
		Hence, the oxidative stress resulting from ischemia should be distinguished from the oxidative stress resulting from hypoxia.
		The potential mechanism of interaction between leukocyte activation and cytokine release during ischemia and reperfusion of the lung.
		Ischemia triggers the activation of passenger macrophages, which release proinflammatory cytokines and mediate reperfusion injury during the early phase of reperfusion.
	ajrccm.atsjournals.org /cgi/content/full/167/4/490 (8962 words)

	Neuronal Death/Survival Signaling Pathways in Cerebral Ischemia -- Sugawara et al. 1 (1): 17 -- NeuroRx (Site not responding. Last check: 2007-11-07)
		Cerebral ischemia and reperfusion generate ROS within mitochondria, which then signal the release of cytochrome c by mechanisms that may be related to the Bcl-2 family proteins, Bcl-2, Bcl-X
		Activation and cleavage of caspase-3 in apoptosis induced by experimental cerebral ischemia.
		Extracellular superoxide dismutase deficiency worsens outcome from focal cerebral ischemia in the mouse.
	www.neurorx.org /cgi/content/full/1/1/17 (4829 words)

	N-Acetylcysteine Enhances Hippocampal Neuronal Survival After Transient Forebrain Ischemia in Rats -- Knuckey et al. 26 ... (Site not responding. Last check: 2007-11-07)
		The results demonstrate that posttreatment with NAC (group 6) effected a significant improvement in neuronal survival compared with vehicle-treated animals (group 5) in animals with transient forebrain ischemia at 45 mm Hg, but there was no significance between groups 7 and 8 with transient forebrain ischemia at 30 mm Hg.
		Ischemia, resuscitation, and reperfusion: mechanism of tissue injury and prospects for protection.
		Cytochemical detection of superoxide in cerebral inflammation and ischemia in vivo.
	stroke.ahajournals.org /cgi/content/full/26/2/305 (3498 words)

	Ischemic Cell Death in Brain Neurons -- Lipton 79 (4): 1431 -- Physiological Reviews
		to anoxia or to anoxia in the absence of glucose (in vitro ischemia)
		of ischemia from the core of the lesion to its outermost boundary,
		In permanent ischemia, the infarct is first seen after 3-12 h (76, 137, 276, 355, 359, 814, 860).
	physrev.physiology.org /cgi/content/full/79/4/1431 (11036 words)

	Cardiac Ischemia - Page 1 - HeartCenterOnline:
		Cardiac ischemia is a situation in which the blood flow inside a
		The blockage within the coronary artery, which supplies the heart with oxygen–rich blood, may be complete or partial.
		However, many episodes of ischemia do not have any associated symptoms (silent ischemia).
	heart.healthcentersonline.com /cholesterol/cardiacischemia.cfm (377 words)

	Ischemia definition - Medical Dictionary definitions of popular medical terms
		Ischemia definition - Medical Dictionary definitions of popular medical terms
		Ischemia: Inadequate blood supply (circulation) to a local area due to blockage of the blood vessels to the area.
		Peripheral Vascular Disease - Peripheral vascular disease (PVD) refers to diseases of the blood vessels (arteries and veins) located outside the heart and brain.
	www.medterms.com /script/main/art.asp?articlekey=4052 (204 words)

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