Where results make sense

About us   |   Why use us?   |   Reviews   |   PR   |   Contact us

Islet cell carcinoma The majority of islet cell cancers are nonfunctional and produce symptoms from tumor bulk or metastatic dissemination. Because of the presence of several cell types in the pancreatic islet cells (alpha, beta, delta, A, B, C, D, E), the term islet cell carcinoma refers to at least five distinct cancers, which when functional, produce unique metabolic and clinical characteristics. Patients with multiple endocrine neoplasia syndrome type 1, an autosomal dominant condition in which 85% have pancreatic islet cell tumors, 90% have hyperparathyroidism, and 65% have pituitary tumors, are less likely to be cured by pancreatic resection than are patients with sporadic islet cell tumors. cancerweb.ncl.ac.uk /cancernet/100790.html   (1984 words)

CANCER - Islet Cell Cancer (Endocrine Pancreas) Islet cell cancer, a rare cancer, is a disease in which cancer (malignant) cells are found in certain tissues of the pancreas. Once islet cell cancer is found, more tests will be done to find out if cancer cells have spread to other parts of the body. Treatment of islet cell cancer depends on the type of tumour, the stage, and the patient’s overall health. www.medic8.com /cancer/islet-cell-carcinoma.htm   (1156 words)

Learn About Basal Cell & Squamous Cell Carcinomas (Carcinoma is cancer that begins in the cells that cover or line an organ.) Basal cell carcinoma accounts for more than 90 percent of all skin cancers in the United States. Both basal and squamous cell cancers are found mainly on areas of the skin that are exposed to the sun -- the head, face, neck, hands, and arms. To check for cancer cells, the tissue is examined under a microscope by a pathologist or a dermatologist. www.mgh.harvard.edu /cancer/crr/types/skin/BasalCell.asp   (1122 words)

M. D. Anderson Cancer Center - Liver Tumor Study Group: Neuroendocrine Tumors Islet cell carcinoma and carcinoid tumors are rare, accounting for less than 1% of all malignant disorders in the United States. Hepatic metastases from carcinoid tumor or islet cell carcinoma are frequently hypervascular because they derive their blood supply predominantly from the hepatic artery. Patients with islet cell carcinoma are often treated with systemic chemotherapy before hepatic artery occlusion, and those with carcinoid tumors are often treated with somatostatin analogue. www.mdanderson.org /departments/ltsg/dIndex.cfm?pn=35E10E16-BBC9-11D4-80FB00508B603A14   (507 words)

Islet Cell Tumors of the Pancreas Islet cell tumors arise from the islets of Langerhans, the endocrine-hormone producing portion of the pancreas. The immunohistochemical expression of the inhibitors of cyclin-dependent kinases p21 and p27 was investigated in 109 endocrine tumors of the pancreas and gastrointestinal tract and compared with that of Ki67 and p53. We report four cases of primary neuroendocrine carcinomas of the pancreas (islet cell tumors) that were characterized by prominent "rhabdoid" features of the tumor cells. www.thedoctorsdoctor.com /diseases/pancreas_isletcelltumors.htm   (6107 words)

NCI: Islet Cell Carcinoma (Endocrine Pancreas) Other islet cell cancers may not make extra hormones and are called nonfunctioning tumors. Hormone therapy uses hormones to stop the cancer cells from growing or to relieve symptoms caused by the tumor. Treatment of islet cell cancer depends on the type of tumor, the stage, and the patient’s overall health. www.jamesline.com /cancertypes/listing/index.cfm?action=Display&ID=62678   (1145 words)

Endotext.com - Chemotherapy for Metastatic Islet Cell Carcinomas Three of four additional patients with malignant islet cell carcinoma associated with glucagonoma syndrome were cited in this report as having responded to dacarbazine alone. The median survival in all patients was 19 months, and the authors concluded that dacarbazine clearly had beneficial activity in patients with advanced islet cell carcinoma. None of six evaluable patients with islet cell carcinoma responded to etoposide in a phase II study (238). www.endotext.org /guthormones/guthormone13/guthormone13.htm   (1259 words)

NTP: ChemIDPlus/HSDB 18883-66-4 Toxicity Islet cells from the pancreases of 20 day old fetuses were isolated and incubated for 30 min with mM of streptozotocin. Insulin release from the pretreated islet cells incubated with 16.5 mM glucose was not increased significantly, compared with a three fold-increase in control islets. Furthermore, the proportion of 2 cell embryos collected from streptozotocin diabetic mice which developed to blastocysts in vitro was similar to that of 2 cell embryos from control mice. ntp.niehs.nih.gov /index.cfm?objectid=E87E4C72-BDB5-82F8-F914AE5F6E0F127A   (3496 words)

Islet Cell Carcinoma (Endocrine Pancreas):   (Site not responding. Last check: 2007-10-25) Danforth DN Jr, Gorden P, Brennan MF Metastatic insulin-secreting carcinoma of the pancreas: clinical course and the role of surgery. However, one large retrospective series has suggested that extensive preoperative radiologic studies are neither clinically effective nor cost-effective, since intraoperative ultrasound and visual inspection of the pancreas at surgery localize most occult insulinomas. Glucagonoma is the third most common endocrine-secreting islet cell tumor and 70% of glucagonomas are malignant. www.acor.org /cnet/62794.html   (2312 words)

Islet cell carcinoma : 00790   (Site not responding. Last check: 2007-10-25) Since the clinical manifestations in functional tumors may result from the metabolic effects of polypeptide(s) secreted by the cancer cells rather than from tumor bulk or metastatic disease, each tumor type must be considered separately, both diagnostically and therapeutically. Islet cells Secreted active agent Tumor and syndrome Alpha Glucagon Glucagonoma (diabetes, dermatitis) Beta Insulin Insulinoma (hypoglycemia) Delta Somatostatin Somatostatinoma (mild diabetes) D Gastrin Gastrinoma (peptic ulcer disease) A -> D Vasoactive Intestinal WDHA (watery diarrhea, Peptide (VIP) and/or hypokalemia, achlorhydria) other undefined mediators serotonin (5-HT) Carcinoid ACTH Cushing's disease MSH Hyperpigmentation There is no detailed or generally accepted staging system for islet cell cancer, although one can logically divide these tumors as follows: islet cell cancers occurring in one site islet cell cancers occurring in several sites islet cell cancers metastatic to regional lymph nodes or distant sites www.acor.org /cnet/100790.html   (1573 words)

Sloan-Kettering - Islet Cell Tumors Islet cell tumors arise in the Isle of Langerhans, a cluster of specialized cells in the part of the pancreas that produces hormones (the endocrine pancreas). Only about 5 percent of pancreatic cancers arise from the islet cells; most pancreatic cancers develop in the part of the pancreas that secretes digestive juices (the exocrine pancreas). Islet cell cancers are usually diagnosed using blood and urine tests (to check levels of hormones) and x-rays or other special imaging tests. www.mskcc.org /mskcc/html/5425.cfm   (270 words)

Islet Cell Tumor of the Pancreas The dense homogeneous enhancement on CT is characteristic of an islet cell tumor. When a diagnosis of islet cell tumor of the pancreas is entertained, MEN syndromes should also be considered in the differential diagnosis. Except for the nonfunctioning islet cell tumor, each secretes an identifiable hormone in the serum to produce a distinct syndrome. brighamrad.harvard.edu /Cases/bwh/hcache/184/full.html   (1151 words)

Pancreatic Islet Cell Tumor   (Site not responding. Last check: 2007-10-25) Islet cell tumors of the pancreas: pathologic-imaging correlation among size, necrosis and cysts, calcification, malignant behavior, and functional status. Nonfunctioning islet cell tumors of the pancreas: a difficult diagnosis but one worth the effort. Islet cell tumors: comparison of dynamic contrast-enhanced CT and MR imaging with dynamic gadolinium enhancement and fat suppression. home.flash.net /~drrad/tf/052499.htm   (291 words)

Islet Cell Carcinoma (Endocrine Pancreas) Many islet cell cancers are nonfunctional and produce symptoms from tumor bulk or metastatic dissemination. Islet cell cancers metastatic to regional lymph nodes or distant sites. The approach to management depends on carefully performed preoperative localization studies and the findings at exploratory laparotomy.[2] [3] [4] However, one large retrospective series has suggested that extensive preoperative radiologic studies are neither clinically effective nor cost-effective, since intraoperative ultrasound and visual inspection of the pancreas at surgery localize most occult insulinomas.[5] www.cancersource.com /Oncology/NCI/48,CDR0000062794   (2269 words)

Functional Islet Cell Tumors - The Merck Veterinary Manual Endocrine pancreatic tissue appears to be derived from multipotential ductal epithelial cells, which differentiate into one of the several cell types present within the islets. Gastrin, somatostatin, pancreatic polypeptide, and vasoactive intestinal peptide may also be produced in excess in islet cell tumors. Because clinical signs are compatible with primary disease of the CNS, functional islet cell tumors may be misdiagnosed as idiopathic epilepsy, brain tumors, or other organic neurologic disease. www.merckvetmanual.com /mvm/htm/bc/40303.htm   (668 words)

eBooks.com - The Official Patient's Sourcebook on Islet Cell Carcinoma eBook Selected readings from various agencies are reproduced to give you some of the latest official information available to date on islet cell carcinoma. While this sourcebook covers islet cell carcinoma, your doctor, research publications, and specialists may refer to your condition using a variety of terms. Therefore, you should understand that islet cell carcinoma is often considered a synonym or a condition closely related to the following: Encephalopathy, Hypoglycemic; islet cell cancer; Islet cell tumors; Islet of Langerhan's tumor; Multiple Endocrine Adenomatosis; Tumor islet cell. www.ebooks.com /cj.asp?IID=213699   (632 words)

Islet Cell Carcinoma (Endocrine Pancreas) -islet cell cancers that have spread to lymph nodes near the pancreas or to distant sites A doctor also needs to know the type of islet cell tumor to plan treatment. Hepatic arterial occlusion or embolization to kill cancer cells growing in www.marystolfacancerfoundation.com /IsletCellCarcinomaEndocrinePancreas.html   (1122 words)

Cancer Information | UPMC Cancer Centers   (Site not responding. Last check: 2007-10-25) Islet cell cancers that make too many hormones are called functioning tumors. Each type of tumor may affect different hormones in the body and cause different symptoms. Hormone therapy (using hormones to stop cancer cells from growing). www.upmccancercenters.com /pdq_xml/cancer.cfm?id=66   (1145 words)

All Islet Cell Neroendecrine Carcinoma messages   (Site not responding. Last check: 2007-10-25) I was diagnosed with a neuroendicrine islet cell tumor in my pancreas(a very large one!) in 2002. It is my understanding that neuroendicrine islet cell tumors are rare and I couldn't find anyone who actually specialized in that area. The article states that it apprears to hinder three types of protien and receptors that cancer cells need to thrive and appears to go after not only the cancer cells, but also the blood vessels that nourish cancerous tumors and the tissue that supports tumors in the body. www.cancercompass.com /message-board/message/all,3599,0.htm   (1251 words)

Pancreas spiral CT scanning protocols: Suspected islet cell tumor However, these authors found both phases necessary to optimize lesion detection as some lesions were poorly seen or not seen in arterial phase. Case 1: islet cell carcinoma of the pancreas Case 2: islet cell carcinoma of the pancreas www.ctisus.com /ctprotocols/pancreas/p1000030.html   (71 words)

NEJM -- Streptozocin-doxorubicin, streptozocin-fluorouracil or chlorozotocin in the treatment of advanced islet-cell ... However, doxorubicin has also been shown to be active against this type of tumor, as has chlorozotocin, a drug that is structurally similar to streptozocin but less frequently causes vomiting. In this multicenter trial, we randomly assigned 105 patients with advanced islet-cell carcinoma to receive one of three treatment regimens: streptozocin plus fluorouracil, streptozocin plus doxorubicin, or chlorozotocin alone. The 31 patients in whom the disease did not respond to treatment were crossed over to chlorozotocin alone or to one of the combination regimens. content.nejm.org /cgi/content/abstract/326/8/519   (818 words)

Pancreatic Cancer, Islet Cell Carcinoma, CancerLinksUSA.com John TG, Greig JD, Carter DC, et al.: Carcinoma of the pancreatic head and periampullary region: tumor staging with laparoscopy and laparoscopic ultrasonography. Dalton RR, Sarr MG, van Heerden JA, et al.: Carcinoma of the body and tail of the pancreas: is curative resection justified? Kelsen D, Hudis C, Niedzwiecki D, et al.: A phase III comparison trial of streptozotocin, mitomycin, and 5-fluorouracil with cisplatin, cytosine arabinoside, and caffeine in patients with advanced pancreatic carcinoma. www.cancerlinksusa.com /pancreas/nci_physician.htm   (2914 words)

Amazon.com: islet   (Site not responding. Last check: 2007-10-25) Islet Transplantation and Beta Cell Replacement Therapy by James Shapiro and James Shaw (Hardcover - April 16, 2007) in a multiendocrine organ, the islet of Langerhans. Islet - Cheap Prices at Calibex -- Cheap Prices on Islet and Millions of Other Products at Calibex. www.amazon.com /s?ie=UTF8&search-alias=aps&keywords=islet&page=1   (431 words)

Medical Dictionary: Islet cell carcinoma - WrongDiagnosis.com Islet cell carcinoma is listed as a "rare disease" by the Office of Rare Diseases (ORD) of the National Institutes of Health (NIH). This means that Islet cell carcinoma, or a subtype of Islet cell carcinoma, affects less than 200,000 people in the US population. Terms that may be interchangeable with Islet cell carcinoma: www.wrongdiagnosis.com /medical/islet_cell_carcinoma.htm   (167 words)

Are these cancers a 'cluster?'  Are they all that rare? For 2-butoxyethanol exposure, this fatigue is autoimmune hemolytic anemia that fools the regular blood info because the red blood cells are small and immature, and their membranes are fragile. I spoke to my mum tonight and she informed me as her breast cancer has re-appeared, her lungs are filling with fluid, and the doctor has found traces of blood, as a result of her white blood cells being high. With this, the white blood cells that fight infection could be turning on your mum and causing an autoimmune situation towards the red blood cells home.gci.net /~blessing/pages/allthatrare.htm   (1043 words)

The Management of Patients with Advanced Carcinoid Tumors and Islet Cell Carcinomas -- Moertel et al. 120 (4): 302 -- ... carcinoma or carcinoid tumor and symptomatic measurable metastatic carcinoid tumor or islet cell carcinoma with metastasis clinically Treatment of metastatic islet cell carcinomas with a somatostatin analogue (SMS 201-995). www.annals.org /cgi/content/full/120/4/302   (3882 words)

Activity Of Imatinib (Gleevec®) In Metastatic Renal Cell Carcinoma - News Activity Of Imatinib (Gleevec®) In Metastatic Renal Cell Carcinoma Until recently, standard therapy for metastatic renal cell carcinoma (RCC) has been immunotherapy with either interleukin 2 or interferon. New targeted therapies that target specific molecular pathways important in malignant transformation and progression have been developed and are currently the subject of intense clinical investigation in a variety of malignancies... goldbamboo.com /news-a170023.html   (172 words)

Islet cell cancer: Treatment - Health Professional Information [NCI PDQ] -- General Information Islet cell cancer: Treatment - Health Professional Information [NCI PDQ] -- General Information This information is produced and provided by the National Cancer Institute (NCI). Since the clinical manifestations in functional tumors may result from the metabolic effects of polypeptide(s) secreted by the cancer cells rather than from tumor bulk or metastatic disease, each tumor type must be considered separately, both diagnostically and therapeutically.[1,2,3] Functional tumors may be too small in size to be detected by conventional imaging techniques. www.webmd.com /hw/cancer/ncicdr0000062794-general-information.asp   (546 words)

Islet cell cancer: Treatment - Patient Information [NCI PDQ] - SJMMC, Ann Arbor, Michigan MI Islet cell cancer: Treatment - Patient Information [NCI PDQ] - SJMMC, Ann Arbor, Michigan MI Online Health Information Islet cell cancer: Treatment - Patient Information [NCI PDQ] To search for documents containing all of your keywords simply enter the words. www.sjmercyhealth.org /14184.cfm   (1870 words)

Common Questions on Merkel Cell Carcinoma Where is the first place I should look for treatment information on merkel cell carcinoma? What are some of the different surgeries that are used to treat merkel cell cancer? I heard that over half of merkel cell cancers metastasize. www.massgeneral.org /cancer/crr/types/skin/questions_merkel_cell.asp   (158 words)

Try your search on: Qwika (all wikis)

About us   |   Why use us?   |   Reviews   |   Press   |   Contact us   Copyright © 2005-2007 www.factbites.com Usage implies agreement with terms.