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| | eMedicine - Toxicity, Alcohols : Article by Ann G Egland, MD |
 | | Approximately 20-50% of isopropanol is excreted unchanged by the kidney, while 50-80% is converted in the liver to acetone, which is a CNS depressant in its own right. |
 | | Isopropanol is a GI irritant that causes abdominal pain, nausea, vomiting, and gastritis with hematemesis. |
 | | Isopropanol toxicity also produces an elevated osmolal gap, but generally no abnormal anion gap, although this may be seen as a result of hypotension and lactic acidosis. |
| www.emedicine.com /emerg/topic19.htm (4747 words) |
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