Itraconazole should be taken with orange juice or cola, as absorption is also improved by acid.
Itraconazole is a relatively well tolerated drug (although not as well tolerated as fluconazole or voriconazole) and the range of adverse effects it produces is similar to the other azole antifungals.
Itraconazole is prescribed by family doctors and general practitioners (whose patients have nail fungus), as well as for AIDS patients (to treat an infection).
Itraconazole oral solution is used to treat yeast infections of the mouth and throat and suspected fungal infections in patients with fever and certain other signs of infection.Itraconazole is in a class of antifungals called triazoles.
Itraconazole capsules are usually taken with a full meal one to three times a day for at least 3 months.
When itraconazole capsules are used to treat fungal infections of the fingernails, they are usually taken twice a day for one week, not taken at all for three weeks, and then taken twice a day for an additional week.
If itraconazole must be used with these medications, it is recommended that at least 2 hours pass between the antacid administration and the administration of itraconazole.
Itraconazole is one of the most expensive medications in used in veterinary medicine.
Itraconazole is able to penetrate most body tissues and thus fight fungal infections in most organs.
Itraconazole is used with caution in any patient with liver dysfunction.
Itraconazole is not used with following medications: terfenadine (Seldane), cisapride (Propulsid), astemizole (Hismanal), triazolam (Halcion) or midazolam (Versed).
Itraconazole is not, however, used for the treatment of isolated onychomycosis (local fungal nail infections) in pregnant women or for those contemplating pregnancy.
This is due to elevated terfenadine concentrations caused by itraconazole.
Based on results of an in vitro study and the chemical resemblance of itraconazole and ketoconazole, coadministration of astemizole and itraconazole is contraindicated.
Itraconazole is a 1:1:1:1 racemic mixture of four diastereomers (two enantiomeric pairs), each possessing three chiral centers.
Itraconazole is an azole medicine used to treat fungal infections.
Itraconazole binds to the fungal p450 enzymes and stops the cells making ergosterol, the main component of the cell wall.
As itraconazole needs acid for its absorption, antacids, H2 antagonists (cimetidine, famotidine, ranitidine) and omeprazole should not be taken for 2 hours after itraconazole.
