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Topic: JC polyomavirus


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In the News (Mon 4 Jun 12)

  
  Polyomavirus - Wikipedia, the free encyclopedia
Polyomavirus is the sole genus of viruses within the family Polyomaviridae.
There are two polyomaviruses found in humans: JC virus, which can infect the respiratory system, kidneys, or brain (sometimes causing the fatal progressive multifocal leukoencephalopathy in the latter case), and BK virus, which produces a mild respiratory infection and can affect the kidneys of immunosuppressed transplant patients.
An avian polyomavirus sometimes referred to as the Budgerigar fledgling disease virus is a frequent cause of death among caged birds.
en.wikipedia.org /wiki/Polyomavirus   (295 words)

  
 Polyomaviruses, JC Virus, BK Virus
JC was first isolated from the brain from a patient suffering from Hodgkin's disease, and suffering from PML.
Polyomavirus replication in permissive cells can be detected by observing CPE or plaque production, by identifying virus particles in cell or culture fluid by EM, by detecting virus antigens using IF, or by observing haemagglutination.
JC and BK viruses are ubiquitous throughout the world, and the 2 viruses circulate independently.
www.virology-online.com /viruses/polyomaviruses.htm   (1487 words)

  
 JC virus - Wikipedia, the free encyclopedia
JC virus or JC polyomavirus is a type of human polyomavirus, genetically similar to BK virus and SV40.
It was discovered in 1971 and named after the initials of the person in whom it was found, a patient with progressive multifocal leukoencephalopathy.
Studies since 2000 have found JC virus in malignant colon tumors and suggested that the virus may be linked to colon cancer.
en.wikipedia.org /wiki/JC_virus   (187 words)

  
 JC Virus Abstracts & Publications : ViraCor Laboratories
JC Virus Load in Progressive Multifocal Leukoencephalopathy: analysis of the Correlation between the Viral Burden in Cerebrospinal Fluid, Patient Survival, and the Volume of Neurological Lesions.
JC virus (JCV) is the causative agent of progressive multifocal leukoencephalopathy (PML), a demyelinating central nervous system infection that mainly affects patients with acquired immunodeficiency syndrome.
Polyomavirus (JC virus[JCV], BK virus [BKV], and simian virus 40 [SV40]) establish subclinical and persistent infections and share the capacity for reactivation from latency in their host under immunosuppression.
www.viracor.com /diagnostic-virals-jc_links.htm   (1199 words)

  
 Specialty Laboratories ::: we help doctors help patients
A polyomavirus known as simian virus 40 (SV40) was introduced into humans through contaminated poliovirus and adenovirus vaccines in use before 1963, at which time, ~90% of children and ~60% of adults received contaminated poliovirus vaccination (cf.#3).
Polyomavirus BK nephropathy causes renal allograft dysfunction in up to 5% of recipients at 40 weeks and results in irreversible renal failure of the allograft in ~45% of the 5%.
Polyomavirus BK nephropathy: a (re-) emerging complication in renal transplantation.
www.specialtylabs.com /books/display.asp?id=424   (1575 words)

  
 Emerging Worlds: Chronic Illness and Viral Infections
The avian polyomavirus referred to as BFDV by the ICTV is not a single entity; three distinct viruses can be distinguished based on DNA sequence analysis and clinical studies, and these three viruses are designated BFDV 1–3 (10).
The fact that polyomavirus DNA is sometimes found in an episomal manner in tumor tissue is reminiscent of the situation with human papillomavirus strain 16 (HPV-16).
The main difficulties in establishing a polyomavirus as an etiologically significant factor in human cancer causation are similar to those that were encountered in studies of cancer induction by HPV (reviewed in Ref. 3,116).
www.emergingworlds.com /pro_article.cfm?link=POLYOMAVIRUSES_AND_HUMAN_TUMORS_Lednicky_and_Butel.htm   (8448 words)

  
 References
Infection of glial cells by the human polyomavirus JC is mediated by an N-linked glycoprotein containing terminal a(2-6)-linked sialic acids.
JC virus DNA is present in many human brain samples from patients without progressive multifocal leukoencephalopathy.
Involvement of JC virus-infected mononuclear cells from the bone marrow and spleen in the pathogenesis of progressive multifocal leukoencephalopathy.
www.medscape.com /content/1999/00/41/75/417570/417570_ref.html   (1596 words)

  
 Progressive multifocal leukoencephalopathy and JC virus genotypes in West African patients with acquired ...
Progressive multifocal leukoencephalopathy and JC virus genotypes in West African patients with acquired immunodeficiency syndrome: a pathologic and DNA sequence analysis of 4 cases.
OBJECTIVE: Progressive multifocal leukoencephalopathy is caused by polyomavirus JC in immunosuppressed patients.
JC virus genotypes are identified by sequence analysis of the viral genome.
www.aegis.com /aidsline/1999/aug/A9980709.html   (493 words)

  
 Immunohistochemical Detection of JC Virus in Nontumorous Renal Tissue of a Patient with Renal Cancer but without ...
JC virus (JCV) is a member of the polyomavirus group of viruses and is the causative agent of progressive multifocal leukoencephalopathy
Detection of BK virus and JC virus in urine and brain tissue by the polymerase chain reaction.
Transmission of the human polyomavirus JC virus occurs both within the family and outside the family.
jcm.asm.org /cgi/content/full/37/4/1165   (1752 words)

  
 CIN'2003. Randhawa. POLYOMAVIRUS INFECTIONS IN KIDNEY TRANSPLANT RECIPIENTS
JC virus genotypes in the western Pacific suggest Asian mainland relationships and virus association with early population movements.
JC virus infection of hematopoietic progenitor cells, primary B lymphocytes, and tonsillar stromal cells: implications for viral latency.
Polyomavirus infection of renal allograft recipients: from latent infection to manifest disease.
www.uninet.edu /cin2003/conf/randhawa/randhawa.html   (3650 words)

  
 ExactAntigen index page for virus species
polyomavirus bk: also called bk polyomavirus, polyomavirus bk, human polyomavirus type bk bkv, polyomavirus hominis 1, papovavirus bkv, human polyomavirus bkv, human polyomavirus bk, human polyomavirus (type bk), bk virus bkv, bk virus, bkv, polyomavirus homonis 1
polyomavirus hominis 1: also called bk polyomavirus, polyomavirus bk, human polyomavirus type bk bkv, polyomavirus hominis 1, papovavirus bkv, human polyomavirus bkv, human polyomavirus bk, human polyomavirus (type bk), bk virus bkv, bk virus, bkv, polyomavirus homonis 1
polyomavirus homonis 1: also called bk polyomavirus, polyomavirus bk, human polyomavirus type bk bkv, polyomavirus hominis 1, papovavirus bkv, human polyomavirus bkv, human polyomavirus bk, human polyomavirus (type bk), bk virus bkv, bk virus, bkv, polyomavirus homonis 1
www.exactantigen.com /taxonomy/virus/p/index.html   (2395 words)

  
 Seminars, Lectures and Presentation
"Molecular characterization of BK and JC viruses from native and renal allograft tissue".
"JC virus infection in the kidney." Sixth Banff Conference on Allograft Pathology, Banff, Alberta, Canada, April 24, 2001.
Polyomavirus allograft nephropathy in kidney transplant recipients: correlation of histologic parameters with changes in immunosuppression.
path.upmc.edu /people/faculty/randhawa/06b.htm   (931 words)

  
 REFERENCES (Molecular Epidemiology of Human Polyomavirus JC in the Biaka Pygmies and Bantu of Central Africa )   (Site not responding. Last check: 2007-11-04)
JC virus regulatory region rearrangements and genotypes in progressive multifocal leukoencephalopathy: two independent aspects of virus variation.
Human polyomavirus JC promoter/enhancer rearrangement patterns from progressive multifocal leukoencephalopathy brain are unique derivatives of a single archetypal structure.
Geographical distribution of the human polyomavirus JC virus type A and B and isolation of a new type from Ghana.
memorias.ioc.fiocruz.br /935/7mref.html   (732 words)

  
 CBER - Simian Virus 40 (SV40:) A Possible Human Polyomavirus Workshop
Two patients with progressive multi focal leukoencephalopathy, a disease we heard about yesterday known to be associated with the JC virus, and born in 1915 and 1933, had SV40 isolated from their brains by techniques that are still reliable.
Again, the purpose of this was to see whether the mesothelioma population as a whole had some difference from a normal population with regard to neutralizing antibodies of T-antigen, and the data is graphically depicted here with the normal volunteers at the bottom and at the top.
Small parts of SV40 put into JC might make JC a bit more active, maybe more tumorigenic, but it might be difficult also to define those SV40 sequences in those JCs unless you do a lot of sequencing.
www.fda.gov /cber/minutes/sv40012897.htm   (17239 words)

  
 American Journal of Kidney Diseases
Although the BK subtype of polyomavirus was first isolated from the urine of a renal transplant recipient in 1971, recognized infection was rare until recently.
Because the histological picture is similar to that in acute rejection and polyomavirus interstitial nephritis can coexist with acute rejection, some patients have undergone treatment for acute rejection along with intensification of their maintenance immunosuppression.
JC polyomavirus is the etiologic agent for progressive multifocal leukoencephalopathy, a disorder of immunocompromised patients characterized by cerebral white matter defects with cortical blindness, hemiparesis, dementia, coma, and death within 6 months.
www.transplantbuddies.org /library/viruses.html   (8053 words)

  
 Bioline International Official Site (site up-dated regularly)
The age and gender of the Biaka and Bantu adults tested for JC viruria is given in the Table.
We conclude that human polyomavirus JCV is excreted in the urine of Biaka Pygmies and Bantus of central Africa, though at a lower rate than that observed in other population groups.
The finding of four different subtypes of JCV in the urine of Biaka Pygmies may be explained by the extensive interactions of Pygmies with their various African tribal neighbors over a long period of time, as they moved from place to place in the equatorial forest.
www.bioline.org.br /request?oc98118   (4876 words)

  
 JC virus - Encyclopedia Glossary Meaning Explanation JC virus   (Site not responding. Last check: 2007-11-04)
JC virus - Encyclopedia Glossary Meaning Explanation JC virus.
Here you will find more informations about JC virus.
The orginal JC virus article can be editet
www.encyclopedia-glossary.com /en/JC-virus.html   (237 words)

  
 Molecular Epidemiology of Human Polyomavirus JC in the Biaka Pygmies and Bantu of Central Africa   (Site not responding. Last check: 2007-11-04)
Molecular Epidemiology of Human Polyomavirus JC in the Biaka Pygmies and Bantu of Central Africa
The presence of multiple subtypes of JCV in Biaka Pygmies may be a result of extensive interactions of Pygmies with their African tribal neighbors during their itinerant movements in the equatorial forest.
The dsDNA polyomavirus JC (JCV) is ubiquitous in humans and bears close sequence homology with other species of this genus, BK virus and the simian virus 40.
memorias.ioc.fiocruz.br /935/7m.html   (1164 words)

  
 Jc Penny Co
Roda JC play in the List of football clubs in the Nethe 21: became Roda JC.
A 56: issues is nanotechnology : the main character JC Denton serves under the flag of UNATCO (Uni 78: ===JC Denton=== 80: embryo.
Michael Moorcock 3: Moorcock, indeed, makes much use of the initials 'JC ', and not entirely coincidentally these are also 13: opular creations was Jerry Cornelius (another JC), a ki...
www.moviewavspage.com /sand/46970-jc-penny-co.html   (730 words)

  
 News Article   (Site not responding. Last check: 2007-11-04)
Researchers from Temple University, Philadelphia, USA have confirmed a link between the common JC polyomavirus and the development of malignant brain tumours of childhood — medulloblastomas.
The human polyoma JC virus (JCV) has received particular attention for its role in a rare, but usually fatal demyelinating disease of the brain known as progressive multifocal leukoencephalopathy (PML), which affects individuals with defective cell-mediated immune responses, such as in AIDS.
The authors conclude that, ‘the finding of agnoprotein expression in the absence of T antigen expression suggests a potential role for agnoprotein in pathways involves in the development of JCV-associated medullablastomas’.
www.mediscover.net /related.cfm?Hnid=561   (673 words)

  
 Utility of JC polyomavirus in tracing the pattern of human migrations dating to prehistoric times -- Pavesi 86 (5): ...
Utility of JC polyomavirus in tracing the pattern of human migrations dating to prehistoric times -- Pavesi 86 (5): 1315 -- Journal of General Virology
Utility of JC polyomavirus in tracing the pattern of human migrations dating to prehistoric times
JC virus (JCV) is a double-stranded DNA polyomavirus co-evolving
vir.sgmjournals.org /cgi/content/abstract/86/5/1315   (314 words)

  
 BK and JC polyomavirus infection in a patient with chronic lymphocytic leukaemia and renal failure -- Fogazzi et al. 17 ...
BK and JC polyomavirus infection in a patient with chronic lymphocytic leukaemia and renal failure -- Fogazzi et al.
BK and JC polyomavirus infection in a patient with chronic lymphocytic leukaemia and renal failure
Human polyomavirus infection with JC virus and BK virus in renal transplant patients.
ndt.oxfordjournals.org /cgi/content/full/17/8/1534   (1113 words)

  
 Quantification of human polyomavirus JC in brain tissue and cerebrospinal fluid of patients with progressive multifocal ...
Quantification of human polyomavirus JC in brain tissue and cerebrospinal fluid of patients with progressive multifocal leukoencephalopathy by competitive PCR.
Activation of human polyomavirus JC (JCV) infection is the cause of the central nervous system (CNS) disease progressive multifocal leukoencephalopathy (PML).
This pointed to an individual course of virus shedding and demonstrates that a controlled competitive PCR system of high accuracy is essential for reliable quantification of virus DNA either in initial diagnosis, in progressive disease or for the evaluation of therapeutic effects.
www.aegis.com /aidsline/2000/apr/A0040342.html   (601 words)

  
 Jc Penney Co
Jc Penney Co Jc Penney Co Comprehensive Analysis
taxon = '''''JC polyomavirus'''''}} 10: '''JC virus''' or '''''JC polyomavirus''''' is a type of human polyomavir 14: Studies since 2000 have found JC virus in malignant colon tumors and suggested
He founded the JC Penney (store)JC Penney department store chain in 1902.
www.moviewavspage.com /sand/25446-jc-penney-co.html   (463 words)

  
 Cooperative action of cellular proteins YB-1 and Pur alpha with the tumor antigen of the human JC polyomavirus ...
Cooperative action of cellular proteins YB-1 and Pur alpha with the tumor antigen of the human JC polyomavirus determines their interaction with the viral lytic control element.
Cooperative action of cellular proteins YB-1 and Pur alpha with the tumor antigen of the human JC polyomavirus determines their interaction with the viral lytic control element.Human JC polyomavirus (JCV) is the etiologic agent of the neurodegenerative disease progressive mulifocal leukoencephalopathy.
Based on the interaction of Pur alpha, YB-1, and TAg, and their binding to DNA, a model is proposed for the role of these proteins in transcription of viral early and late genes during the lytic cycle.
www.pdg.cnb.uam.es /UniPub/iHOP/gp/165441.html   (245 words)

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