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Topic: John E. Sulston

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One man and his worm Sulston spent two years mostly writing the computer programs that made it possible; after that his job was a mixture of computers and exhortation as he got worm researchers around the world to contribute their fragments of DNA to a shared project that would benefit everyone. Sulston was born in 1942; his father was an army chaplain who became an administrator in an Anglican missionary society, and his mother was an English teacher. Sulston believes passionately that the information in genome sequences must be freely available and that it is wrong to patent human gene sequences, both morally and scientifically. www.geocities.com /costisifri/nobel_Sulston.htm   (2822 words)

John E. Sulston - Wikipedia, the free encyclopedia Sir John Edward Sulston PhD,FRS (born 1942) was educated at Pembroke College, Cambridge graduating in 1963. John Sulston FRS interview from the Royal Society Portraits of John Sulston from the National Portrait Gallery (United Kingdom) en.wikipedia.org /wiki/John_Sulston   (364 words)

Royal Society Our work Spotlight on our scientists Scientist profiles featured this month Worm genomics Sir John Sulston’s name is synonymous with the UK’s contribution to the Human Genome Project - an international collaboration to sequence every gene encoded by the DNA contained in our cells. Sir John Sulston was made a Fellow of the Royal Society in 1986. John’s strong conviction that all results of his research should be made freely and publicly available has always been a distinguishing feature of his work on gene sequencing and genomics. www.royalsoc.ac.uk /page.asp?id=1560   (736 words)

BBC - BBC Four Profile - Sir John Sulston John Sulston has a knighthood, a Nobel Prize and the credit for uncovering our genetic instructions for life. Sulston was considered a safe pair of scientific hands to receive a huge cheque and the keys to the Sanger Centre in Cambridge, where he set about directing the British end of the international Human Genome Project. The son of a vicar and a teacher, Sulston was, at an early age, imbued with a strong moral code and curiosity for how things work. www.bbc.co.uk /bbcfour/documentaries/profile/john-sulston.shtml   (422 words)

Biography: John Sulston John Sulston was born in Buckinghamshire on 24 March 1942, the son of a Church of England minister and a schoolteacher. In 2002, John Sulston was awarded the Nobel Prize for Physiology or Medicine jointly with Sydney Brenner and Bob Horvitz, for the work they had done in understanding the development of the worm and particularly the role of programmed cell death. *The Common Thread by John Sulston and Georgina Ferry, Bantam Press 2002. www.wellcome.ac.uk /en/genome/geneticsandsociety/hg13f022.html   (466 words)

John Sulston - 2002 John Sulston was born in 1942 and educated at the Merchant Taylor’s School in Northwood, Middlesex, and at Pembroke College, Cambridge, graduating in 1963. John Sulston determined the cell lineage during the growth of Caenorhabditis elegans. Sulston described the visible steps in the cellular death process and demonstrated the first mutation of a gene participating in programmed cell death, the nuc-1 gene, and in 1983, his group identified two other genes involved, ced-1 and ced-2. www2.mrc-lmb.cam.ac.uk /archive/Sulston02.html   (443 words)

[No title] SBS was honored to recognize Sir John Sulston with the 2002 Achievement Award for his contributions and leadership as the founding director of the Sanger Centre, created by the Wellcome Trust in 1992 to sequence the human genome. Shortly following the SBS Conference, Sir John Sulston was named a recipient of the 2002 Nobel Prize in Physiology or Medicine for his seminal work on programmed cell death in the nematode C. elegans. Sulston's award lecture, "The Common Thread-Our Human Genome," focused on the exciting consequences that are emerging from the human genome sequence. www.sbsonline.org /pu/popup.php?p=../awards_grants/bios/02jSulston.php   (147 words)

British Commercial News Sydney Brenner and Sir John Sulston of the UK shared the Nobel Prize with American Robert Horvitz for their work on how genes control and co-ordinate the division of cells in the body to form tissues and organs. John Sulston and Sydney Brenner’s discovery, therefore, could not only lead the way to drugs that save the lives of millions, but, in the process, spawn an industry whose value could make that of the highly successful monoclonal antibody industry seem like petty change. Sydney Brenner and Sir John Sulston follow the success of Sir Paul Nurse and Tim Hunt of the Imperial Cancer Research Fund (now Cancer Research UK), who won the same prize last year. www.ukinindia.org /htdocs/bcnissu/cedge_1.htm   (837 words)

Press Release: The 2002 Nobel Prize in Physiology or Medicine John Sulston (b 1942), Cambridge, England, mapped a cell lineage where every cell division and differentiation could be followed in the development of a tissue in C. Sulston also showed that the protein encoded by the nuc-1 gene is required for degradation of the DNA of the dead cell. As a result of these findings Sulston made the seminal discovery that specific cells in the cell lineage always die through programmed cell death and that this could be monitored in the living organism. www.nobel.se /medicine/laureates/2002/press.html   (1590 words)

Nat'l Academies Press: The Common Thread: A Story of Science, Politics, Ethics, and the Human Genome John Sulston was the director of the Sanger Centre in Cambridge, England. John Sulston is well placed to relate recent events and to consider their implications. John Sulston, who led the large British contribution to the Human Genome Project, wrote this book with Georgina Ferry, a professional science writer, to put the record straight... www.nap.edu /catalog/10373.html   (2524 words)

AEGiS-Reuters: 'Cell Suicide' Worm Work Wins Medicine Nobel Sydney Brenner and Sir John Sulston of Britain and Robert Horvitz of the United States share the $1 million prize for work on how genes regulate organ development and cell death, said Sweden's Karolinska Institute, which awards the prize. Sulston extended Brenner's work, describing the visible steps of the cell death process and demonstrating the first mutations of genes that took part in the process. Sulston was at his desk at the Sanger Center when he received news of the award. www.aegis.com /news/re/2002/RE021013.html   (830 words)

New Scientist Breaking News - Geneticists and a tiny worm win Nobel prize John Sulston has become well known for his insistence that the human genome should be public property. John Sulston of the Sanger Institute, UK, Sydney Brenner, a UK national working at the Molecular Sciences Institute in Berkeley, US, and H. Robert Horvitz, at the Massachusetts Institute of Technology in Boston, will share the $1 million prize. In 1969, John Sulston joined Brenner at the MRC Laboratory of Molecular Biology in Cambridge to work on C. www.newscientist.com /article.ns?id=dn2890   (714 words)

John Sulston: Hands-on at the Sanger John Sulston says that he became Director of the Sanger Center, spearheading the UK’s contribution to large-scale human genome sequencing, only because he couldn’t see how else he would get the funding to finish his real life’s work, the genome sequence of the nematode worm. Between 1992-2000, Sir John Sulston was Director of the Sanger Centre and led the UK’s involvement in the Human Genome Project. By GF Under the leadership of Sir John Sulston, the Sanger Centre became one of the world’s largest contributors to the Human Genome Project. www.wellcome.ac.uk /en/genome/thegenome/hg01f012.html   (651 words)

Guardian Unlimited Archive Search This is conceptual artist Marc Quinn's depiction of geneticist John Sulston, and is created from Sulston's own DNA (derived, it transpires, from semen helpfully provided by the sitter, and subsequently replicated in bacteria). It was Sulston who argued, more effectively than any other scientist, that should our DNA be rigorously patented, as these companies planned, academics would have to pay fortunes in royalties just for the privilege of trying to achieve a new understanding of the human condition. Sulston's version of this near disaster forms the core of The Common Thread (written with, or more precisely, 'as told to' journalist Georgina Ferry). www.guardian.co.uk /Archive/Article/0,4273,4348541,00.html   (1105 words)

Cafe Scientifique Oxford John Sulston and Georgina Ferry, authors of The Common Thread: a story of science, politics, ethics and the human genome (Bantam Press, February 2002) discuss what the sequencing of the human genome will mean for medical science and for our understanding of ourselves. Sir John Sulston was the Director of the Sanger Centre near Cambridge from 1993-2000, where he led the British team that is sequencing one third of the human genome as part of the international Human Genome Project. The Cafe Scientifique maintains its proud tradition of inviting the most recent Royal Institution Christmas Lecturer to speak, with the invitation of Sir John Sulston in February of the new year. www.cafescientifique.org /oxford/sulston-0202.html   (256 words)

Amazon.com: The Common Thread: A Story of Science, Politics, Ethics and the Human Genome: Books: John Sulston,Georgina Ferry John Sulston's memoirs of the battle for the human genome is deeply written and brutally honest, immersing the reader in a side of science rarely seen by the public. In a book that will remind many of Watson's chronicle, _The Common Thread: A Story of Science, Politics, and the Human Genome_ (Joseph Henry Press), John Sulston, who led the British team on the project, joins with Georgina Ferry, a science writer, to tell how the race was won, and by the good guys. Sulston's early work on the worm provides a nice illustration of resourcefulness: whereas others had found it impossible to observe cell division beyond the first few stages, because the worm would not lie still, Sulston kept it happily immobile by offering it bacterial food right on the microscope slide and continuously recording its divisions. www.amazon.com /exec/obidos/tg/detail/-/0309084091?v=glance   (3520 words)

Columbia News ::: Nobel Laureate John Sulston to Examine Public, Private Ownership of Scientific Information, Nov. 11 John Sulston, winner of the 2002 Nobel Prize in Physiology or Medicine, will offer the Eric Holtzman Memorial Lecture, entitled "The Common Thread: Society and the Human Genome." The lecture will be held on Monday, November 11, at 4:00 p.m. Sulston will discuss the issue of public versus private ownership of scientific information, particularly as it relates to his involvement in the human genome sequencing project. Sulston stepped down as director in September 2000. www.columbia.edu /cu/news/02/11/sulston_lecture.html   (373 words)

CBC News:'Cell suicide' research wins medicine Nobel Sydney Brenner and Sir John Sulston of Britain, and H. Robert Horvitz of the United States shared the prize, worth about $1 million US. Sulston, of the Sanger Centre at England's Cambridge University, extended Brenner's work by describing visible steps in the cell-death process and demonstrating the first mutations of genes that participate in the process. Sulston also sequenced the worm's genome or genetic blueprint in 1998. cbc.ca /stories/2002/10/07/nobel_med021007   (425 words)

The Scotsman - Sci-Tech - Human genome project leader scorns profiteering drug companies Sir John Sulston warned that the benefits of new treatments for major diseases, derived from mapping the human body, were in danger of not being equally shared across the world as a result of the actions of major companies. Sir John, a former director of the Sanger Centre, in Cambridgeshire, which led the UK’s contribution to the human genome project, said pharmaceutical firms were justifying restrictive patents on new drugs by exaggerating the cost of their development. Sir John said if poorer areas of the world did not share in the benefits of such research, it would increase global inequality and the number of people fleeing from poorer countries to Europe. thescotsman.scotsman.com /scitech.cfm?id=934072002   (655 words)

Heritage of humanity, by John Sulston John Sulston is also a principal player in another remarkable scientific endeavour, the human genome project. The 2002 Nobel Prize in physiology or medicine was presented this month to John Sulston, Sydney Brenner and H Robert Horvitz for discoveries about the genetic regulation of organ development and programmed cell death. This article was adapted from John Sulston and Georgina Ferry’s mondediplo.com /2002/12/15genome   (2934 words)

Nobel Prize in Brazil - Events - Science - British Council - Brazil Article on Sir John Sulston for publication in Britcham magazine Sir John, who shared the 2002 Nobel Prize for Medicine visited São Paulo for a day on his way back home after a week in Argentina, and gave a lecture at the Brazilian British Centre on ethics and IP in the field of genomic research. Sir John’s main argument is that IP and patents should be limited to inventions, and not be applicable to natural resources, which belong to humankind. www.britishcouncil.org /brasil-sciences-events-nobel.htm   (797 words)

Why software - in particular embedded software - should not be patented — Debat Public John Sulston was the head of the Sanger Centre, and is a joint winner of the Nobel Prize for Medicine. I have produced various analysis to demonstrate that it is not the case, but none is as compelling as the example described by John Sulston in the book he wrote with Georgina Ferry, titled The Common Thread: Science, politics, ethics and the Human Genome (NAS, Bantam Press, 2002). Because physical machines that embed software have both physical and information components, they conclude that the principles of both should be equally patented. www.debatpublic.net /Members/paigrain/blogue/embedded   (1674 words)

[VanBUG] Bioinformatics Event: Nobel Laureate Dr. John Sulston Upcoming event posted on the Bioinformatics Event Calendar at: http://vanbug.org/event_calendar/ Nobel Laureate Dr. John Sulston Genome BC Presents Nobel Laureate Dr. John Sulston As part of its Distinguished Speaker series, Genome BC is proud to present "From worm cells to the human genome" a lecture by Dr. John Sulston. In 2003 Dr. John Sulston won the Nobel Prize in Physiology or Medicine. Sulston was the Director of the Sanger Centre (established in 1992) where one third of the human genome project was completed. perutz.cmmt.ubc.ca /pipermail/vanbug/announcements/2004-April/000086.html   (286 words)

BBC NEWS Science/Nature Code cracker to be knighted Dr John Sulston led UK scientists in the international project that set out more than a decade ago to read the biochemical "code of life" hidden in nearly all our cells. Dr Sulston, who said the knighthood reflected great credit on all his colleagues, is passionate in his belief that fundamental science should be done "out in the open". The announcement in June that a "rough draft" of the 3bn-letter-long code had been produced was one of the major news stories of 2000. news.bbc.co.uk /hi/english/sci/tech/newsid_1092000/1092690.stm   (490 words)

John Sulston John Sulston graduated from the University of Cambridge in 1963. John Sulston is the Founding Diretor of the Wellcome Trust Sanger Institute. He has worked mainly on the nematode, Caenorhabditis elegans, but latterly has been involved with the sequencing of the human genome. www.cptech.org /events/geneva04292003/js-bio.html   (90 words)

Guardian John Sulston, Marc Quinn (2001) Subject: Sir John Sulston, former director of the Sanger Centre and a leading contributor to the Human Genome Project. It's also a joke on the National Portrait Gallery: although it presents a true likeness of Sulston, it does so in a way that is also a portrait of all of us, in a visual language in which - to the casual eye - we all look the same. The bacteria containing the DNA segments were spread out on agar jelly in the plate you see in the portrait." The transparent entities are colonies of bacteria each grown from a single cell containing a part of Sulston's DNA; at the point of visibility their growth was stopped. www.guardian.co.uk /print/0,3858,4262119-103418,00.html   (442 words)

The Panorama of British Life: Technology, Business, Internet, News, Milestones, Life, People, Upcoming Events John Sulston's team has undertaken to sequence a large fraction of chromosome 22, the whole of chromosome 1, and much of the female sex chromosome the - X chromosome. The Director of the Sanger Centre is Dr John Sulston. Says Sulston "It's styled like a small university campus and the idea of a campus is that you have independently growing institutes which are complementary to one another, so the whole is greater than the sum of the parts. www.britannia.com /panorama/humngene.html   (838 words)

session_7.txt John Sulston: Sanger Centre My justification for being here at all today is my experience with the human genome over the last few years. John Sulston Regarding the question about multiple gene patents, of course, you understand I gave the mildest form of my own philosophy, which did allow some patenting, and I absolutely see the point. The first speaker is Professor Sir John Sulston a very distinguished scientist here in the UK who made substantive contributions to the UK effort on sequencing the human genome. www.iprcommission.org /papers/text/conferences/session_7.txt   (7422 words)

[No title] Sir John Sulston : I think it's not an immediate risk but I think we should look into all possibilities, and this is one reason why I think this information should be open and public so that everyone knows what's going on. Sir John Sulston : Probably the success of cloning depends on resetting the methylation of the DNA as part of the process. Sir John Sulston : Any University or Institute that does molecular biology and molecular genetics - wherever is more convenient for you - you should simply apply in the usual way. www.channel4.com /community/showcards/R/RI_Christmas_Lecture_-_2001.html   (1830 words)

National Portrait Gallery Press releases Genomic portrait Sir John Sulston is the UK's leading figure in the development of DNA analysis and played a pivotal role in the Human Genome Project, an international effort to produce the genetic "book" of humankind. What I like about my portrait of John Sulston is that, even though in artistic terms it seems to be abstract, in fact it is the most realist portrait in the Portrait Gallery since it carries the actual instructions that led to the creation of John. Throughout the 1990's, John Sulston dedicated himself to the Human Genome Project and the portrait captures two of the things which have been fundamental to this venture: John Sulston; and human DNA. www.npg.org.uk /live/prelgeno.asp   (915 words)

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