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Topic: John Sulston


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  John Sulston - 2002
John Sulston was born in 1942 and educated at the Merchant Taylor’s School in Northwood, Middlesex, and at Pembroke College, Cambridge, graduating in 1963.
John Sulston determined the cell lineage during the growth of Caenorhabditis elegans.
Sulston described the visible steps in the cellular death process and demonstrated the first mutation of a gene participating in programmed cell death, the nuc-1 gene, and in 1983, his group identified two other genes involved, ced-1 and ced-2.
www2.mrc-lmb.cam.ac.uk /archive/Sulston02.html   (443 words)

  
 The Telegraph - Calcutta : International
Sulston extended Brenner’s work, describing the visible steps of the cell death process and demonstrating the first mutations of genes that took part in the process.
Sulston is one of the scientists demanding that the genetic blueprint should be freely available, calling genome sequencing for commercial gain “totally immoral and disgusting”.
Sulston was at his desk at the Sanger Centre when he received news of the award.
www.telegraphindia.com /1021008/asp/foreign/story_1273039.asp   (661 words)

  
  One man and his worm
Sulston was born in 1942; his father was an army chaplain who became an administrator in an Anglican missionary society, and his mother was an English teacher.
Sulston spent two years mostly writing the computer programs that made it possible; after that his job was a mixture of computers and exhortation as he got worm researchers around the world to contribute their fragments of DNA to a shared project that would benefit everyone.
Sulston believes passionately that the information in genome sequences must be freely available and that it is wrong to patent human gene sequences, both morally and scientifically.
www.geocities.com /costisifri/nobel_Sulston.htm   (2822 words)

  
 John E. Sulston - Wikipedia, the free encyclopedia
Sir John Edward Sulston PhD,FRS (born 1942) was educated at Pembroke College, Cambridge graduating in 1963.
At this point John was made director of the newly established Sanger Centre (now the Wellcome Trust Sanger Institute), located in Cambridgeshire, UK.
One of Sulston's most important contributions during his research years at the LMB was to elucidate the precise order in which cells in C.
en.wikipedia.org /wiki/John_Sulston   (364 words)

  
 BBC - BBC Four Profile - Sir John Sulston
John Sulston has a knighthood, a Nobel Prize and the credit for uncovering our genetic instructions for life.
The son of a vicar and a teacher, Sulston was, at an early age, imbued with a strong moral code and curiosity for how things work.
Sulston was considered a safe pair of scientific hands to receive a huge cheque and the keys to the Sanger Centre in Cambridge, where he set about directing the British end of the international Human Genome Project.
www.bbc.co.uk /bbcfour/documentaries/profile/john-sulston.shtml   (422 words)

  
 Profile of John Sulston, Nobel Prize-winning scientist | Higher | EducationGuardian.co.uk
Sulston was born in 1942; his father was an army chaplain who became an administrator in an Anglican missionary society, and his mother was an English teacher.
Sulston spent two years mostly writing the computer programs that made it possible; after that his job was a mixture of computers and exhortation as he got worm researchers around the world to contribute their fragments of DNA to a shared project that would benefit everyone.
Sulston believes passionately that the information in genome sequences must be freely available and that it is wrong to patent human gene sequences, both morally and scientifically.
education.guardian.co.uk /higher/sciences/story/0,12243,807366,00.html   (2847 words)

  
 CalendarHome.com - - Calendar Encyclopedia   (Site not responding. Last check: 2007-10-23)
Sir John Edward Sulston PhD, FRS (born March 27, 1942) was educated at Pembroke College, Cambridge graduating in 1963.
At this point John was made director of the newly established Sanger Centre (named after Fred Sanger and now the Wellcome Trust Sanger Institute), located in Cambridgeshire, UK.
John E. Sulston was also a co-author of articles on the new Public Library of Science journal.
encyclopedia.calendarhome.com /cgi-bin/encyclopedia.pl?p=John_E._Sulston   (416 words)

  
 [No title]   (Site not responding. Last check: 2007-10-23)
SBS was honored to recognize Sir John Sulston with the 2002 Achievement Award for his contributions and leadership as the founding director of the Sanger Centre, created by the Wellcome Trust in 1992 to sequence the human genome.
Sulston's award lecture, "The Common Thread-Our Human Genome," focused on the exciting consequences that are emerging from the human genome sequence.
Sulston ended his lecture with some thought-provoking ideas about the preservation of genomic information in the public domain and the disadvantages to society of commercial organizations monopolizing genes.
www.sbsonline.org /pu/popup.php?p=../awards_grants/bios/02jSulston.php   (147 words)

  
 University of Dundee: Graduation 2005 - Ceremony & Events
John Sulston is a scientist who has reached the highest level of recognition in his chosen profession by being awarded the Nobel Prize for Physiology or Medicine in 2002.
John Sulston was born in 1942, the son of an Anglican priest and an English teacher.
The Nobel Prize was subsequently awarded in 2002 to John Sulston, Sydney Brenner and Robert Horvitz for their seminal discoveries on the genetic regulation of organ development which are important for medical research and our understanding of disease.
www.dundee.ac.uk /graduation2005/sulstonlaureation.html   (1177 words)

  
 John Sulston - The Prince of Asturias Foundation
The teams are from The Sanger Centre in the United Kingdom, directed by John Sulston, from the National Human Genome Research Institute, under the leadership of Francis Collins, from Celera Genomics (U.S.A.) led by Craig Venter and Hamilton Smith and from Genoscope in France, under the directorship of Jean Weissenbach.
John Sulston began his scientific career in the seventies at Cambridge, where he graduated in Organic Chemistry, and the obtained his doctorate.
John Sulston has accepted the Prince of Asturias Award on behalf of the International Human Genome Sequencing Consortium, which has released the sequence of the human genome freely and without restriction, for the benefit of all humankind.
www.fundacionprincipedeasturias.org /ing/04/premiados/trayectorias/trayectoria738.html   (296 words)

  
 cell death   (Site not responding. Last check: 2007-10-23)
John Sulston came to Brenner's laboratory in 1969.
As a result of these findings Sulston made the seminal discovery that specific cells in the cell lineage always die through programmed cell death and that this could be monitored in the living organism.
Sulston also showed that the protein encoded by the nuc-1 gene is required for degradation of the DNA of the dead cell.
sps.k12.ar.us /massengale/cell_death.htm   (1803 words)

  
 Sir John Sulston FRS - Worm genomics
Sir John Sulston's name is synonymous with the UK's contribution to the Human Genome Project - an international collaboration to sequence every gene encoded by the DNA contained in our cells.
John was awarded his Fellowship for his early work on the development of the tiny nematode worm Caenorhabditis elegans.
John's strong conviction that all results of his research should be made freely and publicly available has always been a distinguishing feature of his work on gene sequencing and genomics.
www.royalsoc.ac.uk /page.asp?id=1560   (742 words)

  
 AEGiS-Reuters: 'Cell Suicide' Worm Work Wins Medicine Nobel
Sulston extended Brenner's work, describing the visible steps of the cell death process and demonstrating the first mutations of genes that took part in the process.
Sulston also sequenced the worm's genome or its genetic blueprint in 1998, the first time a living animal's genes had been mapped -- akin to creating a geographical atlas or coded instructions needed to make the animal.
Sulston was at his desk at the Sanger Center when he received news of the award.
www.aegis.com /news/re/2002/RE021013.html   (830 words)

  
 Channel4 - Genetics - Lectures - Sir John Sulston
In 1992, Sir John was appointed the first Director of the Sanger Centre in Cambridgeshire which is behind the UK's contribution to the international Human Genome Project.
John Sulston is the co-author, with Georgina Ferry, of The Common Thread: A Story of Science, Politics, Ethics and the Human Genome, to be published by Bantam Press in February 2002, price £17.95.
In October 2002, Sir John Sulston was awarded the 2002 Nobel Prize for physiology and medicine, with Bob Horvitz and Sydney Brenner.
www.channel4.com /learning/microsites/G/genetics/lectures/about.html   (286 words)

  
 Biography: John Sulston
John Sulston was born in Buckinghamshire on 24 March 1942, the son of a Church of England minister and a schoolteacher.
As the leader of one of the four principal sequencing centres in the world, Sulston was a major influence on the Human Genome Project as a whole, particularly in establishing the principle that the information in the genome should be freely released so that all could benefit.
In 2002, John Sulston was awarded the Nobel Prize for Physiology or Medicine jointly with Sydney Brenner and Bob Horvitz, for the work they had done in understanding the development of the worm and particularly the role of programmed cell death.
www.wellcome.ac.uk /en/genome/geneticsandsociety/hg13f022.html   (466 words)

  
 Columbia News ::: Nobel Laureate John Sulston to Examine Public, Private Ownership of Scientific Information, Nov. 11
John Sulston, winner of the 2002 Nobel Prize in Physiology or Medicine, will offer the Eric Holtzman Memorial Lecture, entitled "The Common Thread: Society and the Human Genome." The lecture will be held on Monday, November 11, at 4:00 p.m.
Sulston will discuss the issue of public versus private ownership of scientific information, particularly as it relates to his involvement in the human genome sequencing project.
The lecture brings scientists to the Columbia community to speak on broad issues in the study of science, science education and the impact of science on society, all subjects that Holtzman embraced in addition to his commitment to his research.
www.columbia.edu /cu/news/02/11/sulston_lecture.html   (373 words)

  
 John Sulston: Hands-on at the Sanger
John Sulston says that he became Director of the Sanger Center, spearheading the UK's contribution to large-scale human genome sequencing, only because he couldn't see how else he would get the funding to finish his real life's work, the genome sequence of the nematode worm.
Dr Sulston's first major contribution was to document the lineage of every cell in the adult worm, right back to the fertilised egg.
Between 1992-2000, Sir John Sulston was Director of the Sanger Centre and led the UK’s involvement in the Human Genome Project.
genome.wellcome.ac.uk /doc_wtd020738.html   (700 words)

  
 Nat'l Academies Press: The Common Thread: A Story of Science, Politics, Ethics, and the Human Genome
John Sulston, who led the large British contribution to the Human Genome Project, wrote this book with Georgina Ferry, a professional science writer, to put the record straight...
John Sulston is well placed to relate recent events and to consider their implications.
John Sulston was the director of the Sanger Centre in Cambridge, England.
www.nap.edu /catalog/10373.html   (2524 words)

  
 Whose Genome Is It? — Institute for Genome Sciences and Policy   (Site not responding. Last check: 2007-10-23)
Sulston's is certainly one, and there are others, all of which merit scrutiny as to their effects on scientific productivity and what's best for society.
When Sulston and Bob Waterston (then at Washington University in St. Louis) were tapped to lead the Human Genome Project's sequencing efforts in the 1990s, both brought “the worm ethos” of prompt, open data release to the task.
Rai acknowledges that much of the success of Sulston's open source model was due to the high-profile nature of the human genome and widespread interest in reviewing and refining the data.
www.genome.duke.edu /research/highlights/publicgenomics/whosegenome   (1327 words)

  
 John Sulston: Hands-on at the Sanger
By GF Under the leadership of Sir John Sulston, the Sanger Centre became one of the world’s largest contributors to the Human Genome Project.
John Sulston says that he became Director of the Sanger Center, spearheading the UK’s contribution to large-scale human genome sequencing, only because he couldn’t see how else he would get the funding to finish his real life’s work, the genome sequence of the nematode worm.
Between 1992-2000, Sir John Sulston was Director of the Sanger Centre and led the UK’s involvement in the Human Genome Project.
www.wellcome.ac.uk /en/genome/thegenome/hg01f012.html   (651 words)

  
 Press Release: The 2002 Nobel Prize in Physiology or Medicine
John Sulston (b 1942), Cambridge, England, mapped a cell lineage where every cell division and differentiation could be followed in the development of a tissue in C.
As a result of these findings Sulston made the seminal discovery that specific cells in the cell lineage always die through programmed cell death and that this could be monitored in the living organism.
Sulston also showed that the protein encoded by the nuc-1 gene is required for degradation of the DNA of the dead cell.
www.nobel.se /medicine/laureates/2002/press.html   (1590 words)

  
 [No title]
The first speaker is Professor Sir John Sulston a very distinguished scientist here in the UK who made substantive contributions to the UK effort on sequencing the human genome.
John Sulston: Sanger Centre My justification for being here at all today is my experience with the human genome over the last few years.
John Sulston Regarding the question about multiple gene patents, of course, you understand I gave the mildest form of my own philosophy, which did allow some patenting, and I absolutely see the point.
www.iprcommission.org /papers/text/conferences/session_7.txt   (7422 words)

  
 Fiona’s blog » Sir John Sulston visited Trinity College Dublin
Sulston lead the UK’s contribution to the Human Genome Project which was completed in 2003, and he ensured its open access with a public database to eliminate economic divisions and obstacles in communication, “These problems are avoided with a public database” said Dr. Sulston.
Sulston not only advocated the importance of open access of knowledge but also the importance of public funding in scientific research, so that the quest for knowledge is our main propriety but with private funding our focus is on economic benefits.
Sulston is a rare example of a scientist without training who is confident to openly discuss science with the public although he recognised the need for training when communicating with the public on complex issues, “when dealing with particularly antagonising subjects some scientists’ might find it quite bruising” said John Sulston.
www.vanderpuil.com /?p=17   (557 words)

  
 British Commercial News
Sydney Brenner and Sir John Sulston of the UK shared the Nobel Prize with American Robert Horvitz for their work on how genes control and co-ordinate the division of cells in the body to form tissues and organs.
One of their greatest discoveries was unravelling how certain genes programme some cells to commit suicide at the end of their lives for the greater good of the whole body.
John Sulston and Sydney Brenner’s discovery, therefore, could not only lead the way to drugs that save the lives of millions, but, in the process, spawn an industry whose value could make that of the highly successful monoclonal antibody industry seem like petty change.
www.ukinindia.org /htdocs/bcnissu/cedge_1.htm   (837 words)

  
 John Sulston biography
John Sulston was born in Buckinghamshire on 24 March 1942, the son of a Church of England minister and a schoolteacher.
As the leader of one of the four principal sequencing centres in the world, Sulston was a major influence on the Human Genome Project as a whole, particularly in establishing the principle that the information in the genome should be freely released so that all could benefit.
In 2002, John Sulston was awarded the Nobel Prize for Physiology or Medicine jointly with Sydney Brenner and Bob Horvitz, for the work they had done in understanding the development of the worm and particularly the role of programmed cell death.
genome.wellcome.ac.uk /doc_WTD021047.html   (505 words)

  
 Transworld : Book Details for The Common Thread by John Sulston & Georgina Ferry
John Sulston never meant to become involved in the three ring circus of the Human Genome Project.
Compelling and impassioned, this is not only the story of the most exciting scientific breakthrough in decades, it also reveals the very significant ethical issues involved, in particular Sulston's own quest to ensure that the sequence was freely available and that profit must not be allowed to restrict research.
John Sulston was the director of the Sanger Centre in Cambridge, where he led the British team in their work on the Human Genome Project, for seven years (1993-2000).
www.booksattransworld.co.uk /catalog/book.htm?command=Search&db=twmain.txt&eqisbndata=0552999415   (405 words)

  
 CBC News:'Cell suicide' research wins medicine Nobel   (Site not responding. Last check: 2007-10-23)
Sydney Brenner and Sir John Sulston of Britain, and H. Robert Horvitz of the United States shared the prize, worth about $1 million US.
Sulston, of the Sanger Centre at England's Cambridge University, extended Brenner's work by describing visible steps in the cell-death process and demonstrating the first mutations of genes that participate in the process.
Sulston also sequenced the worm's genome or genetic blueprint in 1998.
cbc.ca /stories/2002/10/07/nobel_med021007   (425 words)

  
 Amazon.com: The Common Thread: A Story of Science, Politics, Ethics and the Human Genome: Books: John Sulston,Georgina ...   (Site not responding. Last check: 2007-10-23)
Sulston's early work on the worm provides a nice illustration of resourcefulness: whereas others had found it impossible to observe cell division beyond the first few stages, because the worm would not lie still, Sulston kept it happily immobile by offering it bacterial food right on the microscope slide and continuously recording its divisions.
Sulston and those who worked with him campaigned for money for their efforts, to be sure, but they were committed to making any data they uncovered public.
John Sulston's memoirs of the battle for the human genome is deeply written and brutally honest, immersing the reader in a side of science rarely seen by the public.
www.amazon.com /Common-Thread-Science-Politics-Ethics/dp/0309084091   (3561 words)

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