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Topic: John Vane


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In the News (Fri 5 Dec 08)

  
  John Robert Vane - Wikipedia, the free encyclopedia
Sir John Robert Vane (March 29, 1927 – November 19, 2004) was a British pharmacologist.
His father was the son of immigrants from Russia and his mother came from a Worcestershire farming family.
Vane completed a doctorate in pharmacology from Oxford University in 1953.
en.wikipedia.org /wiki/John_Robert_Vane   (237 words)

  
 "John Vane - New South Wales Bushranger"
John Vane was born at Jerrys Plains, near Fell Timber Creek and Carcoar in western New South Wales on June 16th.
Vane was still only 20, but they had earned a reputation for daring after stealing a famous racehorse 'Comus 11', and a gelding, from the stables of Mr Thomas Icely at Coombing Park Station, shooting a groom in the face as they escaped.
Vane was enraged and mortified at the loss of his friend and shortly after left the gang to wander the bush alone.
www.wilmap.com.au /bushrangers/vane.html   (770 words)

  
 © The American Physiological Society - John R. Vane
John R. Vane, 77, who shared the Nobel Prize in medicine in 1982 for his part in discovering how aspirin works, died Nov. 19 in Farnborough, England, of complications from fractures suffered this year.
Vane founded the William Harvey Research Institute, specializing in cardiovascular and inflammation research, in 1986, serving first as chairman, then as director general.
Vane was a fellow of the Royal Society, Britain's preeminent academic society, and was knighted in 1984.
www.the-aps.org /membership/obituaries/john_vane.htm   (275 words)

  
 EducationGuardian.co.uk | Special Reports | Sir John Vane
The lasting legacy of the pharmacologist Sir John Vane, who has died aged 77, will be the millions of lives saved each year by the use of daily low-dose aspirin to prevent heart attacks and strokes, and of the angiotensin converting enzyme (Ace) inhibitors for the treatment of high blood pressure and heart failure.
John published around 900 original articles, wrote or edited 20 books, received more than 25 medals, prizes and awards, was made a fellow of around 30 societies or institutions (including Fellowship of the Royal Society in 1974), and was given honorary awards by 17 universities.
John was one of the greatest pharmacologists of the 20th century; for his colleagues, he will be remembered as an outstanding teacher, speaker, writer, thinker, manager, friend and all-round inspiration.
education.guardian.co.uk /obituary/story/0,12212,1359188,00.html   (800 words)

  
 Telegraph | News | Sir John Vane   (Site not responding. Last check: 2007-10-24)
Sir John Vane, who died on Friday aged 77, shared the Nobel Prize for Medicine in 1982 for his discovery, in 1976, of prostacyclin, the blood-vessel dilating prostaglandin that inhibits blood-clotting, and for his earlier work on aspirin.
Vane's discoveries led to new treatments for heart and blood-vessel disease, and to the development and introduction of a new class of life-saving drugs to control pulmonary hypertension - the Ace inhibitors - from which tens of thousands of people around the world have since benefitted.
During this period, when Vane had time for research, he developed, with others, the cascade superfusion bioassay technique for measurement of, dynamically and instantaneously, the release and fate of vasoactive hormones in the circulation or in the perfusion fluid of isolated organs.
www.telegraph.co.uk /news/main.jhtml?view=DETAILS&grid=&targetRule=10&xml=/news/2004/11/22/db2202.xml   (817 words)

  
 Sir John Vane; Nobel laureate who helped decipher aspirin; 77 | The San Diego Union-Tribune
Vane's research with aspirin, already the most widely used drug in the world, also helped advance new therapies for heart and blood vessel disease and contributed to the development of two classes of widely prescribed drugs, the cox-2 inhibitors for pain and inflammation and the ACE inhibitors in blood pressure.
Vane entered the University of Birmingham in 1944 to study chemistry but was discouraged by a lack of enthusiasm there for his desire to experiment.
Vane also helped the development of another class of drugs, the ACE inhibitors (for angiotensin converting enzyme inhibitors), which are widely prescribed to treat high blood pressure, heart failure and other circulatory diseases.
www.signonsandiego.com /uniontrib/20041125/news_1m25vane.html   (637 words)

  
 Boston.com / Your Life / Health & Fitness / Diseases & Treatments / Nobel Prize winner Sir John Vane dies
Vane died Friday in Farnborough of complications from fractures suffered earlier in the year, the University of London said.
Vane showed that aspirin inhibits the production of prostaglandins, ubiquitous hormone-like substances that are involved in body mechanisms ranging from fever to inducing labor.
Vane was a fellow of the Royal Society, Britain's pre-eminent academic society, and was knighted in 1984.
www.boston.com /yourlife/health/diseases/articles/2004/11/22/nobel_prize_winner_sir_john_vane_dies   (326 words)

  
 Bushranger Profiles John Vane
John Vane was born at **James Plains, near Carcoar, New South Wales, in 1842.
John Vane was tried in April 1864 and sentenced to 15 years hard labour for Robbery Under Arms.
John Vane died on 30 January 1906 at Cowra Hospital and is buried in an unmarked grave in Woodstock Cemetery.
scs.une.edu.au /Bushrangers/vane.htm   (1238 words)

  
 HighBeam Encyclopedia - Vane, Sir John Robert   (Site not responding. Last check: 2007-10-24)
VANE, SIR JOHN ROBERT [Vane, Sir John Robert] 1927-2004, British pharmacologist, Ph.D. Oxford, 1953.
With B. Samuelsson and Sune K. Bergström, Vane was awarded the 1982 Nobel Prize in Physiology or Medicine.
Vane's work helped explain the effects on the body of aspirin, the world's most widely used drug and also contributed to the discovery and development of cox-1 and cox-2 inhibitors (see nonsteroidal anti-inflammatory drug).
www.encyclopedia.com /html/V/Vane-Joh.asp   (252 words)

  
 The Genealogy Website of Adams/Simpson - pafg76 - Generated by Personal Ancestral File   (Site not responding. Last check: 2007-10-24)
William Vane was born in 1617 in of,Shiborne,Durham,England.
John Vane was born in 1618 in of,Raby Castle,Durham,England.
Walter Vane Sir was born in 1620 in of,Shiborne,Durham,England.
users.kricket.net /RajinCajun/pafg76.htm   (402 words)

  
 Ned Kelly World - Australia's Famous Bushrangers   (Site not responding. Last check: 2007-10-24)
John Vane was born near Fell Timber Creek (NSW) in 1842 to William Vane, a carpenter, and Ann née Miller.
John was one year older than "Micky", and although both lads never went to school, they were brought up in the bush, where they became superb horsemen.
In August 1863, Vane was with his mate Burke, who stole the famous racehorse Comus II and a gelding from the stables of Mr Thomas Icely at Coombing Park Station.
www.nedkellysworld.com.au /bushrangers/vane_j.htm   (539 words)

  
 JOHN VANE THE BUSHRANGER
Vane upon catching sight of the reverend gentleman, grasped his fire arms, when Mr McCarthy called out that he was a priest, and not a trooper.
Vane is a native of the colony, twenty years of age, stands six feet high, and has a ruddy complexion, with fl hair, and is said to be a Wesleyan.
John McKellar, having turned approver, but, in consequence of his evidence being unsupported, and the other witnesses being unable to identify the prisoners they were all acquitted).
home.iprimus.com.au /kymh/vane.htm   (1358 words)

  
 The Lasker Foundation | Former Award Winners, Basic Medical Research 1946 Obituary
Vane shared the Nobel Prize in Physiology or Medicine in 1982 with Sune K. Bergstrom and Bengt I. Samuelsson, both of the Karolinska Institute in Stockholm.
Vane also helped the development of another class of drugs, the ACE inhibitors (for angiotensin converting enzyme inhibitors), widely prescribed to treat high blood pressure, heart failure and other circulatory diseases.
Vane had to be resuscitated twice; broke his hip; underwent hip replacement surgery; and broke his hip again, Dr. DuBois said.
www.laskerfoundation.org /awards/obits/vaneobit.shtml   (721 words)

  
 John R. Vane Biography / Biography of John R. Vane Anatomy and Physiology Biography
John R. Vane's research on prostaglandins, hormone-like substances produced by the body, proved fundamental in the research and treatment of such illnesses as heart disease, strokes, ulcers and asthma.
Vane was born March 29, 1927, in Tardebigge, Worcester, the son of Maurice Vane and the former Frances Fisher.
Vane's father, the son of Russian immigrants, owned a small manufacturing company; his mother came from a family of farmers.
www.bookrags.com /biography-john-r-vane-wap   (253 words)

  
 Search Results for "vane"
...John Robert, 1927-, British biochemist, Ph.D. Univ. of Oxford, 1953.
With B. Samuelsson and Sune K. Bergstrom, Vane was awarded the 1982 Nobel Prize in Physiology...
Commercial and agricultural fairs and winter sports events are held in the city.
www.bartleby.com /cgi-bin/texis/webinator/65search?query=vane   (284 words)

  
 William Harvey
John returned to the UK in 1955 and W D M Paton appointed him senior lecturer in his department of pharmacology at the Institute of Basic Medical Sciences in London.
Here, John perfected his signature ‘blood bathed organ cascade’, a technique whereby blood or saline solution was passed over a series of strips of smooth muscles chosen for their exquisite sensitivity to the substances under investigation.
John died peacefully of pneumonia in the Princess Royal Hospital in Farnborough, Kent, UK on Friday 19th November, aged 77.
www.williamharvey.co.uk /institute/sirJohnvane.htm   (598 words)

  
 Sir John Vane, founder of the William Harvey Research Institute, has died aged 77 Queen Mary, University of London
Sir John is credited with discovering how aspirin and similar drugs produce their effects; his work provided a scientific basis for the pain-relieving and anti-inflammatory effects of aspirin and also provided an explanation for how aspirin prevented blood clots and helped prevent heart attacks and strokes.
Sir John also assisted with the development of a family of medicines called ACE inhibitors, which are widely used to treat high blood pressure, heart failure and a number of other vascular diseases.
John and I went back a long way and we have interacted in various ways over the years most recently in setting up, with other old and mutual friends, Vanguard Medica which was John's brainchild.
www.qmul.ac.uk /news/newsrelease.php?news_id=107   (5547 words)

  
 peg-2006 - pegg421.htm - Generated by Personal Ancestral File   (Site not responding. Last check: 2007-10-24)
John Vane Overton was born on 17 Jun 1938.
John Scott Bolling was born on 25 Nov 1939 in Brazoria Co., Texas.
John Marvin Coleman was born on 5 Apr 1925 in Chicago, Cook Co., Illinois.
www.patch.net /pegram/pegg421.html   (1021 words)

  
 The Genealogy Website of Adams/Simpson - pafg136 - Generated by Personal Ancestral File   (Site not responding. Last check: 2007-10-24)
John Vane or Fane [Parents] was born about 1503.
John Molineux was born in 1525 in Of,Sefton,Lancashire,Englandire.
John Molyneux was born about 1470 in Of,,Lancashire,England.
users.kricket.net /rajincajun/pafg136.htm   (439 words)

  
 Medicine - Related Items - MSN Encarta
Sulston, Sir John E. Sutherland, Earl Wilbur, Jr.
Vane, John R. Vane, John R. (1927-2004), British pharmacologist and Nobel Prize winner.
Vane's main area of research involved prostaglandins, hormonelike...
encarta.msn.com /related_761567832_54.159/Vane_John_R.html   (37 words)

  
 The Lasker Foundation | Former Award Winners, Clinical Medical Research
He credits Dr. John Vane with suggesting angiotensin converting enzyme as a target for research at The Squibb Institute.
John had a lot of good ideas, and he pushed them, and he was also very helpful in my career.
I don't think John Laragh was actually the first person to test it, but there were some other investigators, one of whose names is evading me right now, who tested it in the clinic and quite soon they started turning out papers on the utility of converting enzyme inhibitors.
www.laskerfoundation.org /awards/library/1999c_int_cd2.shtml   (6144 words)

  
 Pulmonary Hypertension Association
It’s been 20 years since Dr Vane shared the Nobel Prize for his studies of prostaglandins, and his discovery of one of them, prostacyclin, eventually ushered in a new era in the treatment of pulmonary hypertension.
Dr Vane was cited by the Nobel committee for his “discovery of the prostaglandin known as prostacyclin in 1976, and for analyzing its biological effects and function.” Yet it was years before the drug epoprostenol (Flolan) was first used in pulmonary hypertension after Timothy Higenbottam, MD, documented its efficacy in the disease in 1987.
Dr Vane suggested that the synergism could be related to the fact that silde-nafil inhibits consumption of both cyclic GMP and cyclic AMP.
www.phassociation.org /medical/Advances_in_PH/Winter_2002/Sir_John_Vane.asp   (758 words)

  
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He was the Reverend John Vane, Rector from 1828 until his death on 29 December 1870, and Perpetual Curate of Burrington from 1831.
There are quite a few discrepancies in various reference books that mention John Vane, but the consensus has been that he was born in County Durham about 1791 and was the natural son of William Harry Vane (1766-1842), who became the 1st Duke of Cleveland.
One contradictory reference, citing the Record of Dulwich College where John Vane was a Fellow from 1818 to 1848, says he was "the acknowledged natural son of Lord Castlereagh" (Foreign Secretary and Leader of the House of Commons during the post-Napoleonic period).
www.wringtonsomerset.org.uk /history/johnvane.html   (577 words)

  
 John William De Forest - Wikipedia, the free encyclopedia
John William De Forest (May 31, 1826–July 17, 1906) was an American soldier and writer of realistic fiction, best known for his Civil War novel Miss Ravenel's Conversion from Secession to Loyalty.
He was born in Seymour, Connecticut (then called Humphreysville), the son of a prosperous cotton manufacturer.
Works by John William De Forest at Project Gutenberg
en.wikipedia.org /wiki/John_William_De_Forest   (635 words)

  
 Re: General wind vane question
when the rudder correction is applied then the apparent wind direction should come into line with the vane, the vane will straighten out and then so will the oar.
in practice, the vane is constantly moving constantly but oh so slightly, the oar is moving oh so slightly, and the tiller is moving oh so slightly.
John V -- Monday, 22 March 2004, at 12:52 p.m.
cruisenews.net /cgi-bin/windvane/windvane.pl/noframes/read/772   (381 words)

  
 Pirate History: Famous Pirates, Privateers, Buccaneers, and Corsairs U-Z
In another incident, Vane had set out to capture a ship, but when he got closer and realized that it was a larger French Man o' War, he decided to retreat, feeling they were outmatched.
Vane left on another sloop, which was eventually wrecked in a storm off an uninhabited island in the Bay of Honduras.
After a while, another ship finally rescued Vane, but soon after leaving the island, the ship met up with Captain Holford's, and its captain held Vane prisoner, turning him over to the authorities in Jamaica where he was found guilty and hanged.
www.privateerdragons.org /pirates_famous9.html   (1102 words)

  
 Sample Contracts - Consultancy Contract - deCODE genetics Inc. and Vane Associates - Competitive Intelligence for ...
COMMENCEMENT This Agreement shall be deemed to commence with effect from 27 October 1997 and shall continue until the close of business on the third anniversary of the date of this Agreement and thereafter until terminated by either party upon 90 days written notice to the other.
6.3 Sir John Vance and consultant shall execute Non-Disclosure Agreements in favour of Company in the form attached hereto as Exhibit A. 7.1 It is agreed that this Agreement shall enure for the benefit of and be enforceable by the Consultant and its successors in title.
It is particularly understood that the Consultant and/or Sir John Vane are required to fulfil certain obligations to the Affiliated Entities pursuant to the guidelines or the policies if any, adopted by the Affiliated Entities or pursuant to a contract entered into with such Affiliated Entities.
contracts.onecle.com /decode/vane.consult.1997.12.01.shtml   (1061 words)

  
 Vane, Sir Henry - ENCYCLOPEDIA - The History Channel UK
Vane, Sir Henry, 1613-62, English statesman; son of Sir Henry Vane (1589-1655).
During the English civil war, Vane was a consistent moderate and proved himself a very able administrator.
Vane sat in Parliament under Richard Cromwell but, at the fall of Richard's government, argued for the restoration of the Long Parliament.
www.thehistorychannel.co.uk /staging/search/search.php?word=Vane-H2   (514 words)

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