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Topic: Ketone bodies


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In the News (Wed 25 Nov 09)

  
  Ketone bodies - Wikipedia, the free encyclopedia
Ketone bodies are three chemicals that are produced as by-products when fatty acids are broken down for energy.
The three ketone bodies are acetoacetate, beta-hydroxybutyrate and acetone.
Ketone bodies are produced from acetyl-CoA (see ketogenesis) mainly in the mitochondria of liver cells when carbohydrates are so scarce that energy must be obtained from breaking down fatty acids.
en.wikipedia.org /wiki/Ketone_bodies   (470 words)

  
 Ketone - Wikipedia, the free encyclopedia
Acetone, acetoacetate and beta-hydroxybutyrate are ketones (or ketone bodies) generated from carbohydrates, fatty acids and amino acids in humans and most vertebrates.
Ketones are elevated in blood after fasting including a night of sleep, and in both blood and urine in starvation, hypoglycemia due to causes other than hyperinsulinism, various inborn errors of metabolism, and ketoacidosis (usually due to diabetes mellitus).
Ketones are often used in perfumes and paints to stabilize the other ingredients so that they don't degrade as quickly over time.
en.wikipedia.org /wiki/Ketone   (846 words)

  
 Dorlands Medical Dictionary
ketone bodies three substances that are produced by fatty acid and carbohydrate metabolism in the liver, being β-hydroxybutyric acid, acetoacetic acid, and acetone in approximately a 78:20:2 ratio.
a cytoplasmic body of varying appearance, structure, and function closely associated with the nucleus, kinetoplast, and basal body in certain parasitic flagellate protozoa; it is usually connected to the basal body by a fibril or thread, which together are known as the parabasal apparatus.
an ovoid body found in the adventitia of the upper part of the superior bulb of the internal jugular vein; its structure and presumably its function are similar to those of the glomus caroticum (carotid body).
www.mercksource.com /pp/us/cns/cns_hl_dorlands.jspzQzpgzEzzSzppdocszSzuszSzcommonzSzdorlandszSzdorlandzSzdmd_b_17zPzhtm   (3585 words)

  
 Lipid Panel Testing - Cholesterol Management with the CardioChek Analyzer
When ketone bodies are released, they enter the bloodstream, acidify the blood, and are eventually excreted mostly in urine.
Ketonuria: accumulation of ketone bodies in the urine.
Prevention of emergencies in diabetics prone to ketonuria requires close monitoring of the levels of glucose in the blood and ketone bodies in the urine.
www.lipidpanel.com /ketones.htm   (501 words)

  
 Ketone bodies in - Find The Best Ketone bodies in Resources Online   (Site not responding. Last check: 2007-10-07)
Ketone body synthesis in liver is effectively irreversible because the enzyme Ketone bodies, unlike fatty acids and triglycerides, are water-soluble.
Ketone bodies are the physiological response of the animal to insulin deficiency.
Ketone bodies tend to accumulate in the blood and urine of individuals affected by starvation or uncontrolled diabetes mellitus.
tiger-woods-2004.findoutall.com /pft/tiger-woods-2004-ketone-bodies-in.html   (599 words)

  
 AllRefer Health - Serum Ketones (Acetone Bodies, Ketone Bodies - Serum, Ketones - Serum, Nitroprusside Test) - ...
Ketone bodies (acetone, acetoacetic acid, beta-hydroxybutyric) are synthesized by the liver from excess fatty acids.
In normal individuals this serves a useful purpose because certain tissues, especially muscle, can use the fatty acids or ketone bodies for energy in lieu of glucose (which is then saved for the tissues which survive solely on glucose, particularly the brain and red blood cells).
The main causes of significant ketosis (elevated ketone bodies) are uncontrolled diabetes, starvation, and alcoholism.
health.allrefer.com /health/serum-ketones-info.html   (455 words)

  
 Ketone bodies: Facts and details from Encyclopedia Topic   (Site not responding. Last check: 2007-10-07)
Ketone bodies are certain chemicals produced mainly in the liver liver quick summary:
Ketone bodies are transported from the liver through the blood to other tissues, EHandler: no quick summary.
Urine is liquid waste excreted by the kidneys and eventually expelled from the body in a process known as urination....
www.absoluteastronomy.com /encyclopedia/k/ke/ketone_bodies.htm   (1400 words)

  
 Test means and method for detecting ketone bodies - Patent 4147514
As used herein, ketone bodies includes compounds such as acetone, acetoacetic acid and.beta.-hydroxybutyric acid (though the latter is not a ketone).
When the body metabolizes inadequate amounts of carbohydrate because of metabolic disorder or inadequate diet, increased fatty acid metabolism gives rise to the appearance of ketone bodies in the blood (ketonemia) and urine (ketonuria).
The test device of the invention is sensitive to ketone bodies, particularly to acetoacetic acid and acetoacetate in the urine.
www.freepatentsonline.com /4147514.html   (6620 words)

  
 Kelp, Ketone bodies, Ketosis, Kidneys   (Site not responding. Last check: 2007-10-07)
An abnormal accumulation of ketone bodies is known as ketosis.
When severe, ketosis is known as ketoacidosis, because the body becomes over-acidified due to the acidity of two of the ketone bodies.
In all these cases the body is forced to use fat as an alternative energy source, and free fatty acids in the circulation are converted to ketone bodies in the liver.
www.health-diets.net /healthsearch/kelp.htm   (275 words)

  
 Ketosis   (Site not responding. Last check: 2007-10-07)
In scientific terms it is defined as an accumulation of excessive amounts of ketone bodies in body tissues and fluids.
'Ketone bodies' are the metabolic substances acetoacetic acid and beta-hydroxybutyric acid.
During fat mobilization, ketone bodies (one of which produces acetone) are produced and circulated in the blood, hence the names ketosis or acetonemia." Lori notes that most of the accepted ketosis treatments attempt to raise blood glucose in some manner.
hometown.aol.com /goatlist/ketosis.htm   (934 words)

  
 Ketone Bodies
Ketone body synthesis from acetyl CoA occurs in hepatic mitochondria
Therefore, if the demand for ATP is high the fate of acetyl-CoA is likely to be further oxidation to CO The level of fat oxidation is regulated hormonally through phosphorylation of ACC, which may activate it (in response to glucagon) or inhibit it (in the case of insulin).
This allows the heart and skeletal muscles primarily to use ketone bodies for energy, thereby preserving the limited glucose for use by the brain.
home.austin.rr.com /mikeready/KetoneBodies.htm   (436 words)

  
 Fatty Acid Metabolism   (Site not responding. Last check: 2007-10-07)
Ketone bodies are produced in small quantities in healthy persons.
Ketone bodies are synthesized from acetyl-CoA and not surprisingly the excessive accumulation of acetyl-CoA will lead to higher levels of ketone bodies in the liver and blood stream.
One indication that a person is producing ketone bodies at a higher rate is the presence of acetone in the person's breath.
www.np.edu.sg /~dept-bio/biochemistry/aab/topics/aab_lipid.htm   (881 words)

  
 Ketone bodies - Medicine terms   (Site not responding. Last check: 2007-10-07)
When the body does not have the help of insulin, the ketones build up in the blood and then "spill" over into the urine so that the body can get rid of them.
The body can also rid itself of one type of ketone, called acetone, through the lungs.
Ketones that build up in the body for a long time lead to serious illness and coma.
www.encyclopedia-wiki.org /encyclopedias/medicine/Ketone-bodies.html   (95 words)

  
 Ketosis: Mystery or Misconception?   (Site not responding. Last check: 2007-10-07)
The major role of ketone bodies is to supply an alternative (to glucose) fuel for the brain in situations where there are little or no carbohydrates available with food.
Ketone bodies are precursors for the essential substance (acetyl-CoA) required in the synthesis of lipid (myelin) in the neural cells.
The concentration of ketone bodies in the blood at any time represents a balance between the rate of their production by the liver and the rate of their use by tissues.
www.bestlowcarbs.com /article1067.html   (633 words)

  
 ketone bodies - General Practice Notebook   (Site not responding. Last check: 2007-10-07)
Ketonaemia, ketones in the bloodstream, is a physiological consequence of lipid metabolism.
Ketogenesis is the normal pathway by which ketones are formed in the liver.
Ketones are a valuable energy source for tissues such as the brain and muscle.
www.gpnotebook.co.uk /cache/-147521478.htm   (118 words)

  
 CLINICAL AND BIOCHEMICAL STUDIES ON THE BASIS OF KETONE BODIES IN CATTLE : II. URINE KETONE BODIES IN NORMAL DAIRY ...   (Site not responding. Last check: 2007-10-07)
The mean values for the ketone bodies of the normal group were 6.19 (2.12〜43.41) mg/100 ml in total ketone, and 1.25 (0.18〜24.95) mg/100 ml in free acetone.
The mean values for the ketone bodies of the sub-normal group were 122.50 (47.97〜258.00) mg/100 ml in total ketone, and 54.50 (25.83〜123.00) mg/100 ml in free acetone.
In the sub-norml group, not only the increase of the ketone bodies but also increase of the blood sugar level and marked decrease in number of eosinophilic leucocytes were clarified.
hdl.handle.net /2115/1701   (261 words)

  
 CLINICAL AND BIOCHEMICAL STUDIES ON THE BASIS OF KETONE BODIES IN CATTLE : I. BLOOD KETONE BODIES IN NORMAL DAIRY ...   (Site not responding. Last check: 2007-10-07)
The values for the blood ketone bodies of the clinically healthy cows varied so widely that they were statistically divided into 2 groups, viz., "normal and sub-normal groups." 2.
The mean values for the ketone bodies of the normal group were 3.11 (0.99〜11.17)mg/100ml in total ketone, and 0.79 (0.22〜4.53)mg/100ml in free acetone.
The mean values for the ketone bodies of the sub-normal group were 39.10 (12.30〜73.80)mg/100ml in total ketone, and 8.23 (5.20〜10.50)mg/100ml in free acetone.
hdl.handle.net /2115/1699   (233 words)

  
 BioCarta - Charting Pathways of Life
Ketone bodies are transported to other tissues such as brain, muscle or heart where they are converted back to acetyl-CoA to serve as an energy source.
The brain normally uses only glucose for energy, but during starvation ketone bodies can become the main energy source for the brain.
In the metabolic condition called ketosis, ketone bodies are produced faster than they are consumed by tissues and the smell of acetone can be detected on a person's breath.
www.biocarta.com /pathfiles/ketonebodiesPathway.asp   (183 words)

  
 Welcome to Parrillo Performance
As a result, the capacity of the Krebs cycle is overwhelmed and a large proportion of the acetyl-CoA is directed toward the synthesis of ketone bodies (Bach and Babayan, 1982).
Ketone bodies are released from the liver into the blood and are subsequebtly taken up by muscles and used as fuel.
LCT ingestion also causes an increase in blood levels of ketone bodies during fasting, but only MCT will still produce ketone bodies if carbohydrates are concurrently ingested (Sucher, 1986).
www.parrillo.com /sngdetails.asp?sng=mct&id=2   (815 words)

  
 Copper-y smell?
Ketone bodies are synthesized by the liver whenever fatty acid levels are high in the blood.
Under normal conditions there are very few ketone bodies in the blood because they are chewed up as quickly as they are formed.
Excess ketone bodies are made by the liver when blood glucose is kept persistently low or when glucose uptake into cells is not working efficiently.
www.medhelp.org /forums/diabetes/messages/74a.html   (663 words)

  
 HEALTH AND FITNESS GLOSSARY AND DEFINITIONS: K   (Site not responding. Last check: 2007-10-07)
Ketone bodies are typically formed under conditions of glycogen depletion from low-carbohydrate diets or extreme exercise resulting in carbohydrate depletion.
The accumulation of ketone bodies in the body, accompanied by a state of acidosis.
The ability of individuals to feel where their bodies are in relation to space; a body awareness.
www.1-fitness.com /glossary.asp?page=K   (330 words)

  
 Ketone Bodies   (Site not responding. Last check: 2007-10-07)
Some of the benefits result from a shift in the brain's metabolism from blood sugar, the body's main fuel, to ketone bodies, a secondary energy source that is...
The body goes from metabolizing sugar to a much better fuel source -- ketone bodies.
Ketones were first discovered in the urine of diabetic patients in the mid-19th century.Reduction...
www.wikiverse.org /ketone-bodies   (656 words)

  
 Ketone bodies   (Site not responding. Last check: 2007-10-07)
The chemicals acetoacetate acetone and beta-hydroxybutyrate are collectively known as bodies; note that the first two are ketones while the third is not.
Ketone bodies are transported from the liver the blood to other tissues where acetoacetate beta-hydroxybutyrate can be reconverted to acetyl CoA produce energy.
After a three-day 30% of the energy used by the is from ketone bodies.
www.freeglossary.com /Ketone_bodies   (916 words)

  
 Post-exercise ketosis, ketone bodies
"Ketosis" is the name given to any situation where "ketone bodies" accumulate in the blood, and are then partly breathed out, some appears in the urine, but the majority are burnt by the muscles, brain and other tissues of the body.
Their ketone bodies levels in the blood would then be sky high; but what was making them feel faint and dizzy were the low levels of glucose in the blood.
Within minutes the symptoms were gone, and when we tested the blood, ketone bodies could no longer be found, and their blood sugars would be normal.
academic.sun.ac.za /medphys/ketosis.htm   (1735 words)

  
 Ketone bodies
In diabetes, ketone bodies can accumulate in the blood, causing diabetic ketoacidosis, a dangerous condition.
The chemicals acetoacetate, acetone and beta-hydroxybutyrate[?] are collectively known as ketone bodies; note that the first two are ketones while the third isn't.
If glucose levels are low, such as during starvation, the brain uses ketone bodies as energy source instead.
www.fastload.org /ke/Ketone_bodies.html   (505 words)

  
 Atkins Diet -- The Final Verdict
In case you might be curious, the three ketone bodies produced by this alternative pathway for breaking down fat are acetoacetate, beta-hydroxybutyrate, and acetone.
These ketone bodies are formed in your liver and then are transported to other tissues, mainly the brain.
When ketone bodies are circulating in your bloodstream, it signals an abnormal physiologic state, called starvation.
www.weight-loss-professional.com /atkins-diet.html   (1038 words)

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