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Topic: Ketoprofen

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	ketoprofen, Orudis, Oruvail - drug class, medical uses, medication side effects, and drug interactions by ...
		PRESCRIBED FOR: Ketoprofen is used for the treatment of inflammation and pain caused by rheumatoid arthritis and osteoarthritis, as well as soft tissue injuries, such as tendinitis and bursitis.
		Ketoprofen is generally used with caution in patients taking blood thinning medications (anticoagulants), such as warfarin (Coumadin), because of an increased risk of bleeding.
		Ketoprofen is not recommended in children as it has not been adequately studied in younger patients.
	www.medicinenet.com /ketoprofen/article.htm (635 words)

	Ketoprofen - RxList Generic Information
		Ketoprofen is a white or off-white, odorless, nonhygroscopic, fine to granular powder, melting at about 95 deg C. It is freely soluble in ethanol, chloroform, acetone, ether and soluble in benzene and strong alkali, but practically insoluble in water at 20 deg C. Ketoprofen is a nonsteroidal anti-inflammatory drug with analgesic and antipyretic properties.
		Studies in postoperative pain have shown that Ketoprofen in doses of 25 to 100 mg was comparable to 650 mg of acetaminophen with 60 mg of codeine, or 650 mg of acetaminophen with 10 mg of oxycodone.
		Ketoprofen tended to be somewhat slower in onset; peak pain relief was about the same and the duration of the effect tended to be 1 to 2 hours longer, particularly with the higher doses of ketoprofen.
	www.peru.k12.in.us /PJHS/Teacher/Jsites/top200/ketoprof.htm (5863 words)

	[No title] (Site not responding. Last check: 2007-10-28)
		Ketoprofen is contra-indicated in patients with active peptic ulceration, a history of recurrent peptic ulceration or chronic dyspepsia, severe renal dysfunction.
		It is recommended to avoid ketoprofen unless considered absolutely essential, in which case it is advised to discontinue treatment within one week of expected confinement when non-steroidal anti-inflammatory drugs might cause premature closure of the ductus arteriosus or persistent pulmonary hypertension in the neonate.
		Overdosage: Ketoprofen is of low toxicity in overdosage, symptoms after acute ketoprofen intoxication are largely limited to drowsiness, abdominal pain and vomiting, but adverse effects seen after overdosage with propionic acid derivatives such as hypotension, bronchospasm and gastrointestinal haemorrhage should be anticipated.
	www.btinternet.com /~little_willow/barricade/research/ketoprofen.txt (926 words)

	Howstuffworks "Ketoprofen: A Profile of a Pain Reliever"
		Ketoprofen is used to treat rheumatoid arthritis and osteoarthritis.
		Ketoprofen taken concurrently with lithium and cyclosporine may increase the amount of these drugs in the body, increasing their toxic effects.
		Although ketoprofen appears to be safe in animals, studies in pregnant women have not been conducted.
	health.howstuffworks.com /define-ketoprofen.htm (1010 words)

	Square - KOP
		Ketoprofen is rapidly and extensively metabolized in the liver, principally via conjugation with glucoronic acid.
		Ketoprofen is used for symptomatic relief of mild to moderate pain, such as postoperative (including that associated with dental surgery) postpartum and orthopedic (including musculoskeletal strains or sprains) pain and visceral pain associated with cancer.
		Ketoprofen should be used with caution in patients with heart failure, hypertension, or other conditions associated with fluid retention, since peripheral edema has been observed in some patients receiving the drug.
	www.bdorth.org /Kop.html (1041 words)

	Ketoprofen (Site not responding. Last check: 2007-10-28)
		Ketoprofen is a non-steroidal anti-inflammatory drug (NSAID) labelled for use in horses for the alleviation of inflammation and pain associated with musculoskeletal disorders.
		It is for this reason that if ketoprofen is used in conjunction with medications that alter blood flow (heparin, warfarin etc.), or medications that cause gastrointestinal erosion (aspirin, flunixin, phenylbutazone, corticosteroids, etc.) there is an increased likelihood of bleeding or ulceration.
		Ketoprofen may falsify results of blood glucose levels, serum bilirubin and serum iron levels during certain laboratory tests.
	www.oaep.on.ca /MedsSheets/Ketoprofen.htm (570 words)

	Data Sheet
		Ketoprofen is a potent non-steroidal anti-inflammatory aryl carboxylic acid derivative belonging to the propionic acid group of NSAIDs.
		The biotransformation of ketoprofen is characterised by two main processes, hydroxylation and conjugation with glucuronic acid, the latter being the main pathway in man. Excretion of ketoprofen as unchanged drug is very low (less than 1%).
		Almost all administered ketoprofen is excreted as metabolites in the urine, of which 65 to 85% of administered dose is excreted as a glucuronide metabolite.
	www.medsafe.govt.nz /Profs/Datasheet/o/Orudiscap.htm (1387 words)

	Ketoprofen For Veterinary Use
		Ketoprofen is commonly used for the management of musculoskeletal pain due to soft tissue injury, synovitis, and osteoarthritis in horses.
		Ketoprofen may also be used in the management of colic for protection from bacterial toxins (endotoxemia), however, flunixin meglumine is more commonly used for this purpose.
		Ketoprofen should be used in breeding animals with caution, when the potential benefits outweigh the potential risks.
	www.wedgewoodpharmacy.com /monographs/ketoprofen.asp (975 words)

	Ketoprofen for migraine
		Ketoprofen given as a rectal suppository or an intramuscular injection is effective for the acute treatment of migraine.
		A systematic review of ketoprofen was not found so Bandolier pulled together the evidence for this drug for the acute treatment of migraine.
		Inclusion criteria were: treatment of acute migraine with ketoprofen by any route; randomised allocation to treatment groups; double-blind design; adult population and headache outcomes.
	www.jr2.ox.ac.uk /bandolier/booth/Migraine/ketacute.html (393 words)

	Ketoprofen (Ketofen®)
		Ketoprofen is primarily used to treat pain and inflammation associated with arthritis and other musculoskeletal disorders.
		Ketoprofen should be avoided in animals with liver, heart or blood abnormalities.
		Ketoprofen is available in 12.5 mg, 25 mg, 50 mg and 75 mg tablets and as 100 mg, 150 mg and 200 mg extended-release tablets.
	www.petplace.com /drug-library/ketoprofen-ketofen/page1.aspx (556 words)

	MedicineHouse.com
		The antipyretic activity of Ketoprofen may occur secondary to inhibition of pyrogen induced release of prostaglandins in the central nervous system (including the hypothalamus) and possibly to centrally mediated peripheral vasodilation.
		Ketoprofen may cause peripheral edema and should also be used cautiously in patients with heart failure, hypertension and other conditions associated with fluid retention.
		Ketoprofen should be avoided in such patients as it may cause a dose-dependent decrease in prostaglandin formation and thus precipitate renal decompensation (3) Observe carefully patients with coagulation disorders and those receiving drug therapy that interferes with hemostasis.
	www.medicinehouse.com /cgi-bin/drug.php?drug=ketoprofen (960 words)

	Ketoprofen - Drugs & Vitamins - Drug Library - DrugDigest
		Ketoprofen helps relieve the inflammation and pain associated with rheumatoid arthritis, osteoarthritis, menstrual cramps or premenstrual pain and swelling.
		Ketoprofen is available in a non-prescription strength to treat minor aches and pains associated with the common cold, backache, muscular aches, toothache and menstrual pain.
		It is especially important not to use ketoprofen during the last 3 months of pregnancy unless specifically directed to do so by your health care provider.
	www.drugdigest.org /DD/DVH/Uses/0,3915,364\|Ketoprofen,00.html (978 words)

	Ketoprofen Drug Information, Professional
		Diflunisal, fenoprofen, ibuprofen, indomethacin, ketoprofen, meclofenamate, phenylbutazone, and tolmetin are used in the treatment of psoriatic arthritis.
		The antibradykinin activity of ketoprofen may also be involved in relief of pain, because bradykinin has been shown to act together with prostaglandins to cause pain.
		The antibradykinin activity of ketoprofen may also be involved in relief of dysmenorrhea, because bradykinin has been shown to induce uterine contractions and to act together with prostaglandins to cause pain.
	www.drugs.com /mmx/ketoprofen.html (3922 words)

	Ketoprofen.com - The official site for ketoprofen information
		Ketoprofen is in a class of drugs called nonsteroidal anti-inflammatory drugs (NSAIDs).
		Ketoprofen is used to reduce pain, inflammation, and stiffness caused by many conditions such as osteoarthritis, rheumatoid arthritis, and abdominal cramps associated with menstruation.
		Ketoprofen is more effective than tramadol for analgesia during early recovery after tonsillectomy in children
	www.ketoprofen.com (407 words)

	Ketoprofen Topical - Patient UK
		Ketoprofen is used to relieve pain and inflammation in the muscles, tendons and joints, it is also used for pain caused by rheumatism.
		Ketoprofen works by reducing the effect of irritant chemicals which are produced by the body as a response to inflammation.
		Ketoprofen may cause your skin to become more sensitive to sunlight than it is usually.
	www.patient.co.uk /showdoc/30003700 (692 words)

	Ketoprofen (Site not responding. Last check: 2007-10-28)
		Ketoprofen is used to treat rheumatoid arthritis, osteoarthritis, and ankylosing spondylitis.
		Though there is no research available to show that ketoprofen increases lithium blood levels, until more information is available, people taking ketoprofen should talk with their healthcare practitioner before supplementing with lithium.
		Ketoprofen may cause stomach upset and should therefore be taken with food.
	www.kroger.com /hn/Drug/Ketoprofen.htm (545 words)

	MedlinePlus Drug Information: Ketoprofen
		Prescription ketoprofen is used to relieve pain, tenderness, swelling and stiffness caused by osteoarthritis (arthritis caused by a breakdown of the lining of the joints) and rheumatoid arthritis (arthritis caused by swelling of the lining of the joints).
		Nonprescription ketoprofen is used to relieve minor aches and pain from headaches, menstrual periods, toothaches, the common cold, muscle aches, and backaches, and to reduce fever.
		Stop taking nonprescription ketoprofen and call your doctor if your symptoms get worse, you develop new or unexpected symptoms, the part of your body that was painful becomes red or swollen, your pain lasts for more than 10 days or your fever lasts for more than 3 days.
	www.nlm.nih.gov /medlineplus/druginfo/medmaster/a686014.html (1235 words)

	ketoprofen - Drug Finder - MSN Health & Fitness (Site not responding. Last check: 2007-10-28)
		Ketoprofen is used to reduce pain, inflammation, and stiffness caused by many conditions, such as osteoarthritis, rheumatoid arthritis, and abdominal cramps associated with menstruation.
		Ketoprofen must not be taken late in pregnancy (the third trimester) because a similar drug is known to affect the baby's heart.
		Ketoprofen may increase the sensitivity of the skin to sunlight.
	health.msn.com /drugfinder/articlepage.aspx?cp-documentid=100106359 (1396 words)

	Ketoprofen - Patient UK
		Ketoprofen belongs to the group of medicines known as non-steroidal anti-inflammatory drugs (NSAIDs).
		Ketoprofen is used to relieve pain and swelling in sprains, strains, backache and rheumatic diseases.
		Ketoprofen works by preventing the production of chemicals that cause pain and inflammation in the body.
	www.patient.co.uk /showdoc/30002015 (1028 words)

	RedOrbit - Health - Effect of Ketoprofen in Topical Formulation on Vascular Endothelial Growth Factor Expression and ... (Site not responding. Last check: 2007-10-28)
		Ketoprofen (KP) has been used as an analgesic to relieve the acuity of post-operative pain [32] and chronic cancer pain [31].
		The aim of the present study is to examine whether percutaneous treatment of tumor-bearing mice with KP is a useful means for cancer therapy.
		An open, randomized study of ketoprofen in patients in surgery for achilles or patellar tendinopathy.
	www.redorbit.com /news/display/?id=100727 (4053 words)

	Ketoprofen May Cause Serious Stomach Problems
		This is the first scientific study to report on the potential gastrointestinal (GI) effects of recommended OTC doses of ketoprofen.
		The randomised, double-blind, three-way crossover study compared 75mg/day of ketoprofen, with 4,000mg/day of acetaminophen, the medicine in Tylenol(TM) and a placebo.
		The condition of the stomach lining and the upper portion of the small intestine was graded to assess the extent of injury.
	www.docguide.com /dg.nsf/PrintPrint/3EE059835EB40BC685256647004D1393 (541 words)

	ketoprofen Consumer Drug Information
		Ketoprofen may also be used for purposes other than those listed in this medication guide.
		You may not be able to take ketoprofen, or you may require a dosage adjustment or special monitoring during treatment if you have any of the conditions listed above.
		Ketoprofen is in the FDA pregnancy category B. This means that it is not expected to be harmful to an unborn baby.
	www.drugs.com /MTM/ketoprofen.html (1383 words)

	warfarinfo
		It is more likely that the increased PT was due to a change in the sensitivity of the materials used in the test than from ketoprofen.
		Ketoprofen is known to decrease platelet adhesion and aggregation.
		Miezczak and Winther, in 1993, on a double-blind placebo-controlled study with 15 healthy, male volunteers that ketoprofen had no significant effect on the anticoagulant effect of warfarin.
	www.warfarinfo.com /ketoprofen.htm (250 words)

	Ketoprofen (Site not responding. Last check: 2007-10-28)
		Ketoprofen is a nonsteroidal anti-inflammatory drug (NSAID) used to treat minor aches and pains associated with the common cold, headache, muscle aches, backache, and arthritis.
		Ketoprofen may also be used to reduce fever.
		Ketoprofen works by blocking the enzyme in your body that makes prostaglandins.
	www.prescriptiondrugchat.com /showthread.php?t=1083 (302 words)

	[No title] (Site not responding. Last check: 2007-10-28)
		It is not known whether etodolac, floctafenine, ibuprofen, ketoprofen, nabumetone, oxaprozin, sulindac, or tiaprofenic acid passes into human breast milk.
		DR Mehlisch: Ketoprofen, ibuprofen, and placebo in the treatment of primary dysmenorrhea: a double-blind crossover comparison J Clin Pharmacol 1988 28: 29.
		Ketoprofen, ibuprofen, and placebo in the treatment of primary...
	members.lycos.co.uk /clickforme/ketoprofenibuprofen.html (597 words)

	Orudis (Ketoprofen) drug description - prescription drugs and medications at RxList
		Ketoprofen is a white or off-white, odorless, nonhygroscopic, fine to granular powder, melting at about 95
		(ketoprofen) capsules contain 25 mg, 50 mg, or 75 mg of ketoprofen for oral administration.
		(ketoprofen) 100 mg, 150 mg, or 200 mg capsule contains ketoprofen in the form of hundreds of coated pellets.
	www.rxlist.com /cgi/generic/ketoprof.htm (400 words)

	Veterinary Products... ketoprofen
		After seven days, by which time swelling, heat, pain, and lameness had developed in all study animals, each horse was given a single intravenous injection of ketoprofen at the randomly assigned dosage of 0 (placebo), 0.5, 1.0 or 1.5 mg/lb body weight.
		Controls were given placebo (vehicle not containing ketoprofen) injections at the rate of 1 mL/100 lb body weight.
		Dosage form was ketoprofen injectable solution containing 100 mg ketoprofen per ml, identical to the formulation to be marketed.
	www.betterchem.com /vet/ketoprofen.htm (745 words)

	Ketoprofen Tissue Permeation in Swine Following Cathodic Iontophoresis -- Panus et al. 79 (1): 40 -- Physical Therapy
		Total ketoprofen concentrations recovered in the skin and underlying fascia following either 40 minutes of cathodic iontophoresis at 4 mA or 40 minutes of passive delivery.
		No differences were observed between iontophoretic and passive ketoprofen permeation at either skin or fascia depths, as determined by a 2-tailed paired t test (N=5).
		.05) were demonstrated for total ketoprofen concentrations between the initial 1 cm of muscle tissue and subsequent depths within a given delivery protocol.
	www.ptjournal.org /cgi/content/full/79/1/40 (4025 words)

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