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Topic: Klebsiella

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Klebsiella pneumoniae

Proteus (bacterium)

Enterobacteriaceae

Gram staining

Alpha Proteobacteria

Escherichia coli

Gamma Proteobacteria

	Medmicro Chapter 26
		Klebsiella pneumoniae causes a severe pneumonia; K rhinoscleromatis causes rhinoscleroma; and K ozaenae is associated with ozena, an atrophic disease of the nasal mucosa.
		Klebsiella rhinoscleromatis is the agent of rhinoscleroma, a chronic destructive granulomatous disease of the respiratory tract that is endemic in Eastern Europe and Central America.
		Klebsiella ozaenae, a rare cause of serious infection, is classically associated only with ozena, an atrophy of nasal mucosal membranes with a mucopurulent discharge that tends to dry into crusts; however, recent studies indicate that the organism may cause various other diseases including infections of the urinary tract, soft tissue, middle ear, and blood.
	gsbs.utmb.edu /microbook/ch026.htm (5353 words)

	Klebsiella
		Klebsiella is the genus name for one of these bacteria found in the respiratory, intestinal, and urinogenital tracts of animals and man. When Klebsiella bacteria get outside of the gut, however, serious infection can occur.
		Klebsiella pneumoniae is known as a resident of the intestinal track in about 40% of man and animals.
		Klebsiella pneumoniae infection: a review with reference to the water-borne epidemiologic significance of K. pneumoniae presence in the natural environment.
	www.sproutnet.com /Reports/klebsiella.htm (830 words)

	Klebsiella - MicrobeWiki
		Klebsiella are non-motile, rod-shaped, aerobic bacteria that possess a prominent polysaccharide capsule.
		Klebsiella pneumoniae and Klebsiella oxytoca are both opportunistic pathogens found in the environment and in mammalian mucosal surfaces; they are commonly passed by hands of hospital personel.
		Two rarer infections caused by Klebsiella bacteria are rhinoscleroma, a "chronic inflammatory process involving the nasopharynx," and ozena, a "chronic atrophic rhinitis characterized by necrosis of nasal mucosa and mucopurulent nasal discharge" (Emedicine).
	microbewiki.kenyon.edu /index.php/Klebsiella (670 words)

	CDC - Community-Acquired Klebsiella pneumoniae Bacteremia: Global Differences in Clinical Patterns
		It is a common hospital-acquired pathogen, causing urinary tract infections, nosocomial pneumonia, and intraabdominal infections.
		When pneumonia due to Klebsiella was first described by Friedlander in 1882, he believed it to be the most common cause of bacterial pneumonia (37).
		Klebsiella pneumonia in the modern era: clinicoradiographic correlations.
	www.cdc.gov /ncidod/eid/vol8no2/01-0025.htm (4130 words)

	M4: peritoneal Klebsiella pneumoniae
		Klebsiella pneumoniae was proved in her jejunal juice by bacteriologic examination.
		Resistance to ceftriaxone and pefloxacin emerged, respectively, in 15 percent and 83 percent of animals with Klebsiella pneumoniae, 71 percent and 54 percent with Enterobacter cloacae, 0 percent and 83 percent with Serratia marcescens, 25 percent and 100 percent with Pseudomonas aeruginosa, and 0 percent with both Escherichia coli and Staphylococcus aureus.
		RU-41740, a purified glycoprotein extract from Klebsiella pneumoniae, (which is an efficient non-specific immune activator in a broad spectrum of in vitro and in vivo reactions) was administered either orally or parenterally in the mouse.
	members.jorsm.com /~binstock/mike-4.htm (8008 words)

	KLEBSIELLA (Site not responding. Last check: 2007-09-11)
		Klebsiella's pathogenicity can be attributed to its production of a heat-stable enterotoxin.
		Klebsiella infections are encountered far more often now than in the past.
		Klebsiella species may contain resistance plasmids (R-plasmids) which confer resistance to such antibiotics as ampicillin and carbenicillin.
	medic.med.uth.tmc.edu /path/00001506.htm (132 words)

	Klebsiella pneumoniae*
		The Klebsiellae are distinguished by the presence of a capsular polysaccharide, of which there are 77 antigenic types.
		Although Klebsiella pneumoniae can cause a severe pneumonia, it is most commonly the cause of hospital-acquired urinary tract infections or burn wound infections.
		The virulence of Klebsiella is not well understood, but its antiphagocytic capsule plays a role in the lung infections by preventing phagocytosis.
	medinfo.ufl.edu /year2/mmid/bms5300/bugs/klebpne.html (202 words)

	KLEBSIELLA: One Potentially Nasty Bacteria
		Klebsiella is the genus name for one of these bacteria.
		Mortality in Klebsiella pneumonia is fairly high due to the underlying disease that tends to be present in affected persons.
		Other common hospital-acquired infections caused by Klebsiella are urinary tract infections, surgical wound infections and infection of the blood (known as bacteremia).
	www.personalmd.com /news/klebsiella_102299.shtml (759 words)

	Say No To GMOs! - Klebsiella Planticola
		However, Michael Holmes discovered that the engineered bacterium, Klebsiella planticola with a additional alcohol gene, killed all the wheat plants in microcosms into which the engineered organisms was added 1.
		Klebsiella planticola is merely an example that human beings can engineer organisms that can cause serious problems.
		Effects of Klebsiella planticola SDF20 on soil biota and wheat growth in sandy soil.
	www.saynotogmos.org /klebsiella.html (2443 words)

	eMedicine - Klebsiella Infections : Article by Obiamiwe Umeh, MBBS
		Klebsiellae may be regarded as normal flora in many parts of the colon and intestinal tract and in the biliary tract.
		Klebsiella pneumonia characteristically affects one of the upper lobes of the lung, although infection of the lower lobes is not uncommon.
		Wounds may be infected with Klebsiella organisms as the sole pathogens or as a component of a multipathogenic infection.
	www.emedicine.com /med/topic1237.htm (5853 words)

	Treatments for "Klebsiella pneumoniae"
		According to the University of Florida Medical School, " The autoimmune disease, ankylosing spondylitis, is thought to be a possible sequela of Klebsiella infection." This is part of the discussion of the disease on theeir Medinfo page at http://www.medinfo.ufl.edu/year2/mmid/bm...
		Klebsiella is normal flora in the intestines and it is rumored that some inmates force other inmates to ingest fecal matter.
		Please respond, I'm afraid this klebsiella is eating away of the lung tissue.
	www.suite101.com /discussion.cfm/microbiology/46588/31-40 (1278 words)

	M5: neurologic Klebsiella pneumoniae
		Escherichia coli, Clostridium sp, Klebsiella pneumoniae, Enterococcus sp, Staphylococcus epidermidis, and S intermedius were the most common bacteria isolated from hepatic abscesses.
		Septic metastatic endophthalmitis from Klebsiella pneumoniae liver abscess, first reported in seven cases treated at the Veterans General Hospital, Taipei, Taiwan, between 1981 and 1985, was seen in six similar cases at the same hospital in the subsequent 2 years.
		Klebsiella pneumoniae liver abscess, bacteremia, and the underlying diabetes mellitus were significantly more common in the study group than in the comparison group.
	members.jorsm.com /~binstock/mike-5.htm (3306 words)

	Klebsiella pneumoniae - Wikipedia, the free encyclopedia
		Klebsiella pneumoniae is a Gram-negative, nonmotile, encapsulated, lactose-fermenting, facultatively anaerobic, rod-shaped bacterium found in the normal flora of the mouth, skin, and intestines.
		Klebsiella possesses a chromosomal class A beta-lactamase giving it inherent resistance to ampicillin.
		Klebsiella pneumoniae is often called Friedländer's Pneumonia, after Carl Friedländer.
	en.wikipedia.org /wiki/Klebsiella (327 words)

	eMedicine - Klebsiella Infections : Article Excerpt by: Obiamiwe Umeh, MBBS
		Background: The genus Klebsiella belongs to the tribe Klebsiellae, a member of the family Enterobacteriaceae.
		Klebsiellae are nonmotile, rod-shaped, gram-negative bacteria with a prominent polysaccharide capsule.
		These are (1) Klebsiella pneumoniae, (2) Klebsiella ozaenae, (3) Klebsiella rhinoscleromatis, (4) Klebsiella oxytoca, (5) Klebsiella planticola, (6) Klebsiella terrigena, and (7) Klebsiella ornithinolytica.
	www.emedicine.com /med/byname/klebsiella-infections.htm (530 words)

	Klebsiella spp. as Nosocomial Pathogens: Epidemiology, Taxonomy, Typing Methods, and Pathogenicity Factors -- Podschun ... (Site not responding. Last check: 2007-09-11)
		Klebsiella species are usually identified and differentiated according to their biochemical reactions.
		Immunogenicity of a 24-valent Klebsiella capsular polysaccharide vaccine and an eight-valent Pseudomonas O-polysaccharide conjugate vaccine administered to victims of acute trauma.
		A hospital epidemic caused by a gentamicin-resistant Klebsiella aerogenes.
	cmr.asm.org.cob-web.org:8888 /cgi/content/full/11/4/589 (7091 words)

	Klebsiella
		The reason for proposing Klebsiella as a causative agent of ankylosing spondylitis is that specific antibodies to this microbe, but not to twelve others, have been demonstrated (Ebringer, 105).
		If Klebsiella is the cause of the inflammation, then removal should lead to a drop in level of acute phase reactants and no new damage should occur in patients.
		Though this data was consistent with the proposed theories on Klebsiella, it does not prove it (Ebringer,117).
	www.chem.fsu.edu /editors/learn/kleb.htm (1088 words)

	Capsule Impedes Adhesion to and Invasion of Epithelial Cells by Klebsiella pneumoniae -- Sahly et al. 68 (12): 6744 -- ...
		Klebsiella pneumoniae is an opportunistic pathogen involved in outbreaks of nosocomial infections, such as bacteremia and
		The primary contribution of CPS to the pathogenicity of Klebsiella appears to be by rendering the bacteria resistant to phagocytosis
		Klebsiella capsular type K7 in relation to toxicity, susceptibility to phagocytosis and resistance to serum.
	iai.asm.org /cgi/content/full/68/12/6744 (4562 words)

	Klebsiella pneumoniae
		Klebsiella pneumoniae is commonly isolated from industrial and environmental biofilms.
		Klebsiella pneumoniae produces large "sticky" colonies when plated on nutrient media.
		Klebsiella pneumoniae is an opportunistic pathogen which causes pneumonia.
	www.thelabrat.com /restriction/sources/Klebsiellapneumonia.shtml (69 words)

	Surfactant Protein D Binds Selectively to Klebsiella pneumoniae Lipopolysaccharides Containing Mannose-Rich O-Antigens ...
		Klebsiella to the epithelial cells was 3 µg/ml for the
		Klebsiella pneumoniae lipopolysaccharide O typing: revision of prototype strains and O-group distribution among clinical isolates from different sources and countries.
		O-antigen seroepidemiology of Klebsiella clinical isolates and implications for immunoprophylaxis of Klebsiella infections.
	www.jimmunol.org /cgi/content/full/169/6/3267 (6145 words)

	KickAS.org - ANKYLOSING SPONDYLITIS IS CAUSED BY KLEBSIELLA
		Ankylosing spondylitis (AS) is caused by Klebsiella pneumoniae infection.
		ANTIBODY against Klebsiella is produced in the lymph nodes draining the lower ileum, and they are located in the mesentery, which is attached to the anterior aspect of the lumbar spines.
		Nevertheless, the clear demonstration that there is cross-reactivity between HLA-B27 and a Klebsiella protein, and the independent demonstration that the Klebsiella microbe is found in AS patients during active phases of the disease, is consistent with the predictions of the molecular mimicry model.
	www.kickas.org /medical/11.shtml (6731 words)

	Structural and Functional Features of Modified Heat-Stable Toxins Produced by Enteropathogenic Klebsiella Cells -- ... (Site not responding. Last check: 2007-09-11)
		Transformed ESMS of the new toxins from Klebsiella AL55, toxins A-1 (a), A-2 (b), and B (c).
		coli ST1b and by Klebsiella toxins A-1, A-2, and B. The kinetics of guanylate cyclase activation in response to E.
		coli ST1b and to Klebsiella toxins A-1, A-2, and B were similar, indicating similar biologic effects of the toxin isoforms.
	www.pedresearch.org /cgi/content/full/48/5/685 (3195 words)

	The aadB Gene Cassette Is Associated with blaSHV Genes in Klebsiella Species Producing Extended-Spectrum ...
		Patterns of resistance associated with integrons, the extended-spectrum ß-lactamase SHV-5 gene, and a multidrug efflux pump of Klebsiella pneumoniae causing a nosocomial outbreak.
		The resistance and integrase genes of pACM1, a conjugative multiple-resistance plasmid, from Klebsiella oxytoca.
		The cassettes and 3' conserved segment of an integron from Klebsiella oxytoca plasmid pACM1.
	aac.asm.org /cgi/content/full/49/2/794 (2003 words)

	Klebsiella pneumoniae Produces No Histamine: Raoultella planticola and Raoultella ornithinolytica Strains Are Histamine ...
		Klebsiella pneumoniae Produces No Histamine: Raoultella planticola and Raoultella ornithinolytica Strains Are Histamine Producers -- Kanki et al.
		Purification and properties of pyridoxal-5'-phosphate-dependent histidine decarboxylases from Klebsiella planticola and Enterobacter aerogenes.
		Klebsiella terrigena, a new species from soil and water.
	aem.asm.org /cgi/content/full/68/7/3462 (2041 words)

	Klebsiella Infection
		The most clinically important species of this genus is Klebsiella pneumoniae.
		The efficacy of Klebsiella pneumoniae bacteriophage in the therapy of experimental Klebsiella infection
		Klebsiella pneumoniae urinary tract infection complicated by endophthalmitis, perinephric abscess, and ecthyma gangrenosum.
	www.phageinternational.com /pathogens/klebsiella.htm (413 words)

	STAT4 Is a Critical Mediator of Early Innate Immune Responses against Pulmonary Klebsiella Infection -- Deng et al. 173 ...
		Klebsiella pneumoniae is a major Gram-negative pathogen in patients
		Alveolar macrophages are required for protective pulmonary defenses in murine Klebsiella pneumoniae: elimination of alveolar macrophages increases neutrophil recruitment but decreases bacterial clearance and survival.
		Leukotriene-deficient mice manifest enhanced lethality from Klebsiella pneumoniae in association with decreased alveolar macrophage phagocytic and bactericidal activities.
	www.jimmunol.org /cgi/content/full/173/6/4075 (4581 words)

	Killing of Klebsiella pneumoniae by human alveolar macrophages -- Hickman-Davis et al. 282 (5): 944 -- AJP - Lung ...
		Klebsiella were washed twice with HBSS, resuspended with sterile water, and total Klebsiella-associated SP-A was measured by indirect ELISA and expressed as total nanograms of SP-A. Data are ± SE, n = 4 performed in duplicate.
		in Klebsiella CFUs by 60 min and a 68% decrease in CFUs by 120
		Alveolar macrophages are required for protective pulmonary defenses in murine Klebsiella pneumonia: elimination of alveolar macrophages increases neutrophil recruitment but decreases bacterial clearance and survival.
	ajplung.physiology.org /cgi/content/full/282/5/L944 (7654 words)

	Molecular Serotyping of Klebsiella Species Isolates by Restriction of the Amplified Capsular Antigen Gene Cluster -- ...
		Klebsiella genus the cps gene cluster responsible for the synthesis
		Genomic organization of the Klebsiella pneumoniae cps region responsible for serotype K2 capsular polysaccharide synthesis in the virulent strain Chedid.
		Epidemiology of quinolone resistance of Klebsiella pneumoniae and Klebsiella oxytoca in Europe.
	jcm.asm.org /cgi/content/full/42/8/3388 (6054 words)

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