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Topic: Krebs cycle


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  Krebs’ Cycle Intermediates: Maximizing Your Body's Performance Edge
Krebs proposed a specific metabolic pathway within the cells to account for the oxidation of the basic components of food — carbohydrates, protein and fats —; for energy.
Interconversions of Krebs’ cycle intermediates are controlled by enzymes that often require vitamin-derived cofactors and minerals to operate.
The Krebs’ cycle is an eloquent and essential system designed to generate large amounts of cellular energy required for life.
www.nutritionreview.org /library/krebs.html   (4591 words)

  
  What is the Krebs Cycle?
The Krebs cycle refers specifically to a complex series of chemical reactions in all cells that utilize oxygen as part of their respiration process.
Within the Krebs cycle, energy in the form of ATP is usually derived from the breakdown of glucose, although fats and proteins can also be utilized as energy sources.
The Krebs cycle affects all types of life and is, as such, the metabolic pathway within the cells, which chemically converts carbohydrates, fats and proteins into carbon dioxide and converts water into serviceable energy.
www.wisegeek.com /what-is-the-krebs-cycle.htm   (356 words)

  
 Carolina: Science Quizzes: Krebs
Krebs researched intermediate metabolism, eventually explaining how foodstuffs are oxidized to produce energy in chemical processes known as the Krebs cycle (also known as the tricarboxylic acid cycle and the citric acid cycle).
Hans Adolf Krebs was born in 1900 to a well-educated professional family in Germany.
At Sheffield, Krebs first demonstrated the citric acid cycle (Krebs cycle) in 1937, which led to a basic understanding of cell metabolism and molecular biology.
www.carolina.com /quiz/krebs.asp   (457 words)

  
 BioCarta - Charting Pathways of Life
One source of the acetyl-CoA that enters the Krebs cycle is the conversion of pyruvate from glycolysis to acetyl-CoA by pyruvate dehydrogenase.
As the cycle proceeds, the Krebs cycle intermediates are oxidized, transferring their energy to create reduced NADH and FADH2.
The activity of the Krebs cycle is closely linked to the availability of oxygen, although none of the steps in the pathway directly use oxygen.
www.biocarta.com /pathfiles/krebPathway.asp   (466 words)

  
 Krebs cycle — FactMonster.com
Krebs cycle, series of chemical reactions carried out in the living cell; in most higher animals, including humans, it is essential for the oxidative
This cycle, also known as the citric acid cycle, was named in recognition of the German chemist Hans Krebs, whose research into the cellular utilization of glucose contributed greatly to the modern understanding of this aspect of metabolism.
Hence the Krebs cycle is sometimes referred to as the tricarboxylic acid (TCA) cycle.
www.factmonster.com /ce6/sci/A0828225.html   (465 words)

  
  Krebs Cycle   (Site not responding. Last check: )
The Krebs Cycle is the central metabolic pathway in all aerobic organisms.
In reality, the Krebs Cycle is not only part of the pathway for the breakdown of glucose but also for the breakdown of all metabolites, including other sugars, amino acids and fatty acids.
This reaction is not really part of the Krebs Cycle, however, since pyruvate is most often generated by glycolysis (which occurs in the cytoplasm of the cell) and the oxidation of pyruvate occurs in the mitochondrion, it is usually associated with the cycle.
www.austincc.edu /emeyerth/krebs.htm   (433 words)

  
  AllRefer.com - Krebs cycle (Biochemistry) - Encyclopedia   (Site not responding. Last check: )
Krebs cycle, series of chemical reactions carried out in the living cell; in most higher animals, including humans, it is essential for the oxidative metabolism of glucose and other simple sugars.
The breakdown of glucose to carbon dioxide and water is a complex set of chemical interconversions called carbohydrate catabolism, and the Krebs cycle is the second of three major stages in the process, occurring between glycolysis and oxidative phosphorylation.
This cycle, also known as the citric acid cycle, was named in recognition of the German chemist Hans Krebs, whose research into the cellular utilization of glucose contributed greatly to the modern understanding of this aspect of metabolism.
reference.allrefer.com /encyclopedia/K/Krebscyc.html   (510 words)

  
  Krebs cycle - HighBeam Encyclopedia   (Site not responding. Last check: )
Krebs cycle series of chemical reactions carried out in the living cell; in most higher animals, including humans, it is essential for the oxidative metabolism of glucose and other simple sugars.
The breakdown of glucose to carbon dioxide and water is a complex set of chemical interconversions called carbohydrate catabolism, and the Krebs cycle is the second of three major stages in the process, occurring between glycolysis and oxidative phosphorylation.
This cycle, also known as the citric acid cycle, was named in recognition of the German chemist Hans Krebs, whose research into the cellular utilization of glucose contributed greatly to the modern understanding of this aspect of metabolism.
www.encyclopedia.com /doc/1E1-Krebscyc.html   (698 words)

  
 Krebs Cycle | World of Microbiology and Immunology
The Krebs cycle is a set of biochemical reactions that occur in the mitochondria.
The Krebs cycle is the final common pathway for the oxidation of food molecules such as sugars and fatty acids.
The Krebs cycle is a cycle because, during its course, it regenerates one of its key reactants.
www.bookrags.com /research/krebs-cycle-wmi   (577 words)

  
 Pyruvate & Krebs.96
Pyruvate is decarboxylated to acetyl-CoA by the pyruvate dehydrogenase complex and the acetyl-CoA is oxidized by the Krebs cycle.
The Krebs Cycle is subject to a major drain of intermediates by the conversion of oxaloacetate to aspartic acid (needed for making Asn, Met, Lys, Thr and Ile) and of ketoglutarate to glutamic acid (for Gln, Arg, Pro).
Remember, the acetyl-CoA which enters the Krebs cycle is all turned into CO Contrast this with the synthesis of alanine from pyruvate or of serine from 3-phosphoglyceric acid which pose no problem because glycolysis is a linear pathway and new intermediates are constantly made from glucose.
www.science.siu.edu /microbiology/micr425/425Notes/05-PyrKrebs.html   (2256 words)

  
 Krebs Cycle | World of Biology
The Krebs cycle is part of the process used by cells to convert foodstuffs, such as carbohydrates, into usable energy.
The Krebs cycle is primarily a catabolic process because it breaks down larger carboxylic acids into smaller units.
The first step of the Krebs cycle acts upon a material known as acetyl coenzyme A (acetyl CoA), which is a derivative of the vitamin called pantothenic acid.
www.bookrags.com /research/krebs-cycle-wob   (674 words)

  
 Krebs Main Page   (Site not responding. Last check: )
The Krebs cycle, or citric acid cycle, was put forth to account for the oxidation of carbohydrates by animal tissues.
Of course, later the acetyl derivative (a compound formed in fat degradation) was identical to the compound formed by the oxidative decarboxylation of pyruvate; thus proving that the Krebs cycle also serves for the oxidation of fats.
Krebs' later work showed that the cycle is not restricted to animals, but rather is present in nearly all aerobic cells.
incolor.inetnebr.com /mcanaday/main.htm   (234 words)

  
 citric acid cycle
Krebs identified the citric acid cycle in 1937 by noting that small quantities of organic acids such as succinate, malate or citrate stimulated oxygen uptake by minced pigeon breast muscle.
The Krebs cycle enzymes are soluble proteins located in the mitochondrial matrix space, except for succinate dehydrogenase, which is an integral membrane protein that is firmly attached to the inner surface of the inner mitochondrial membrane, where it communicates directly with components in the respiratory chain.
Krebs cycle intermediate concentrations depend on the activity of ancillary enzymes, which add material to the cycle from amino acid or carbohydrate sources, or alternatively remove intermediates for use in biosynthetic reactions.
www.bmb.leeds.ac.uk /illingworth/metabol/krebs.htm   (1238 words)

  
 Krebs Cycle: glycolysis krebs cycle, krebs cycle animation, krebs citric acid cycle
The citric acid cycle (also known as the tricarboxylic acid cycle, the TCA cycle, or the Krebs cycle, after Hans Adolf Krebs who identified the cycle) is a series of chemical reactions of central importance in all living cells that use oxygen as part of cellular respiration.
In aerobic organisms, the citric acid cycle is part of a metabolic pathway involved in the chemical conversion of carbohydrates, fats and proteins into carbon dioxide and water to generate a form of usable energy.
The citric acid cycle also provides precursors for many compounds such as certain amino acids, and some of its reactions are therefore important even in cells performing fermentation.
advantacell.com /wiki/Krebs_Cycle   (1047 words)

  
 Hans Krebs
It was in Berlin that Krebs became an assistant of Otto Warburg (Nobel Prize recipient in 1931) at the Kaiser Wilhelm Institute for Biology until 1930.
In 1932, he discovered the urea cycle (reactions in animal organisms that produces urea from ammonia) and the citric acid cycle (series of chemical reactions of central importance in all living cells that utilize oxygen as part of cellular respiration) in 1937.
Krebs was awarded the Nobel Prize for Medicine in 1953, along with Fritz Lipmann.
www.jewishvirtuallibrary.org /jsource/biography/Hans_Krebs.html   (262 words)

  
 Krebs Cycle - Search Results - MSN Encarta
Krebs Cycle, series of chemical reactions occurring within the cell, responsible for the final breakdown of food molecules to form carbon dioxide,...
Although ATP is often regarded as an energy store for the reactions of the body, it is perhaps better to regard it as a means of transferring energy...
- metabolic energy cycle: a sequence of biochemical reactions occurring in cells that is part of the metabolism of carbohydrates to produce energy
uk.encarta.msn.com /Krebs_Cycle.html   (136 words)

  
 Hans Krebs - brief biography
Prior to Krebs discovery, experiments by T. Thunberg and F. Batelli and L.S. Stern revealed that minced animal tissues contained substances that could transfer hydrogen atoms from specific intracellular organic acids (including succinate, malate, and citrate) to methylene blue dye, reducing it to a colorless form.
Krebs discovered the formation of citrate from oxaloacetate and pyruvate, the 'missing link' that allowed the known reactions to form a cyclic sequence.
Krebs' own account of the history of the discovery of the cycle can be found in his article, The History of the Tricarboxylic Acid Cycle, Perspect.
www.ruf.rice.edu /~bioslabs/studies/mitochondria/krebs.html   (591 words)

  
 Essays Page
A cycle of reactions that is universally important in living cells for respiration and biosynthesis.
In eukaryotic cells it takes place in the matrix of mitochondria, whereas in prokaryotic cells the Krebs cycle enzymes are associated with the plasma membrane.
The Krebs cycle also plays a central role in providing building blocks for a range of biosynthetic pathways, including synthesis of various amino acids, cytochromes, and fatty acids.
www.fofweb.com /Subscription/Science/Helicon.asp?SID=2&RecordType=Definition&iPin=ffdmolec1034   (297 words)

  
 Krebs cycle — Infoplease.com
Krebs cycle, series of chemical reactions carried out in the living cell; in most higher animals, including humans, it is essential for the oxidative
Experimental reduction of predators reverses the crash phase of small-rodent cycles.
The impact of predator-induced stress on the snowshoe hare cycle.
www.infoplease.com /ce6/sci/A0828225.html   (553 words)

  
 Krebs Cycle Chelates by Enzymatic Therapy - Medwing.com, Inc.
Krebs Cycle Chelates are a scientifically balanced combination of major and trace minerals, including boron, chelated to the Krebs cycle intermediates.
The Krebs cycle intermediates are a unique chain of five organic acids: citrate, fumarate, malate, succinate, and alpha ketoglutarate.
The Krebs cycle is the final common pathway for converting carbohydrates, fats, and proteins into chemical energy.
www.medwing.com /product/763948077519.html   (347 words)

  
 Controlled oxidation of substrates: selected Krebs cycle mechanisms
The citric acid cycle is also called the Krebs cycle, after Hans Krebs, who first proposed its cyclic nature.
Unfortunately, such a presentation may leave students with the impression that metabolites follow a linear progression through glycolysis to acetyl-coenzyme A to citric acid, through the Krebs intermediates to oxaloacetate, which is then coupled to the two carbons of another acteyl-coenzyme A to regenerate citric acid.
They must be replaced in order to maintain energy balance, however the fate of a Krebs intermediate is not necessarily to cycle through the enzymes until it is completely oxidized to carbon dioxide and water.
www.ruf.rice.edu /~bioslabs/studies/mitochondria/mitokrebs.html   (924 words)

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