| |
| | T-wave alternans could surpass LVEF as risk-stratifier for ICD implantation |
 | | In the T-wave Alternans in Heart Failure (TWA in HF) trial, the TWA test "was at least twice as strong in predictive value as ejection fraction, which is an incredibly good risk stratifier," Dr J Thomas Bigger (Columbia University, New York, NY), told heartwire. |
 | | The population consisted of 549 mostly male patients in sinus rhythm and an LVEF <40% (average 25%) who were in NYHA class 1-3, divided nearly evenly between those with ischemic and nonischemic cardiomyopathy. |
 | | Although at least one prior study has suggested that TWA isn't predictive of death and ventricular arrhythmias among patients with a prolonged QRS interval,[5] according to the common definition also used in Bigger's study, retrospective data from the TWA in HF trial suggests the opposite. |
| www.alternanza.it /Bigger.htm (1033 words) |
|