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| | AATOD: AATOD's Policies |
 | | LAAM should not be continued in patients with confirmed QTc prolongation greater than 480 msec (milliseconds) without timely cardiologic consultation. |
 | | LAAM is metabolized to active metabolites by the cytochrome P450 isoform, CYP3A4. |
 | | All potential LAAM patients are to have medical histories updated with emphasis on a family history (of long QT syndrome, cardiac conduction defects, arrhythmias, syncopal attacks, seizures, and sudden or unexpected death); and personal history (of long QT syndrome, cardiac conduction defects, arrhythmias, syncopal attacks, seizures, palpitations, dizziness, and light-headedness). |
| www.aatod.org /policy_clinical.html (1340 words) |
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