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Topic: Lamin


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In the News (Sat 14 Nov 09)

  
  Lamin 8, North Wales, UK - Decorative board lamination services
Lamin 8, North Wales, UK - Decorative board lamination services
Lamin 8 are specialists in decorative board lamination and we offer a range of outstanding services including full cutting, edging and CNC facilities, all making use of the very latest technology to create extra impact, reduce costs and improve efficiency.
Adopting a way of working that keeps ahead of even the fastest-moving projects, Lamin 8 consistently delivers a level of service and a range of benefits that few if any other decorative board companies can match.
www.lamin8.co.uk   (86 words)

  
  BioMed Central | Full text | Altered protein dynamics of disease-associated lamin A mutants
In the absence of lamin A, emerin relocates from the INM to the endoplasmic reticulum [3,5,6].
By NMR and circular dichroism the structure and thermostability of the R482W mutant is similar to that of wt lamin A [26].
Our analysis of protein dynamics suggests that an altered interaction between emerin and lamin A could alter the stability of the nuclear lamina, reflected in the increased mobility of lamin A. Missense mutations in the coiled-coil domain of lamin A are associated with the myopathies, not FPLD (Figure 1).
www.biomedcentral.com /1471-2121/5/46   (4822 words)

  
 Antibodies to Lamin Proteins
Lamins form dimers through their rod domain and interact with chromatin and integral proteins of the inner nuclear membrane through binding sites located in their carboxy-terminal globular tail.
A-type lamins A and C are derived by differential splicing and alternative polyadenylation from one gene, the LMNA gene.
Lamin A is a 664 amino acid protein with a molecular weight of 70 kDa (calculated 74,139 Da) and a pI of 7.0 (theoretical pI 7.4).
www.acris-antibodies.com /focus_review/focus0028-Lamin.php?region_filter=&lg=en   (526 words)

  
 Lamin A/C (LMNA) homepage
Lamin B3 is germ cell specific protein generated by differential splicing and alternative polyadenylation of the LMNB2 gene (Furukawa and Hotta, 1993).
The lamins are components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane which is suggested to provide a framework for the nuclear envelope and may interact with chromatin.
WRN; Werner's syndrome (OMIM: 277700) is a progeroid syndrome caused by mutations at the WRN helicase locus.
www.dmd.nl /lmna_home.html   (2308 words)

  
 Lamin Lodge: the restaurant on stilts in the midst of the river Gambia
Lamin Lodge is a three-story wooden construction on stilts, overlooking the mangroves of the river Gambia.
Lamin Lodge is basically a restaurant, but it is also the point of departure for many of GRE's excursions.
Lamin Lodge also has a few plastic kayaks for rent, that can be used by people who want to discover the surrounding creeks on their own tempo.
www.gambiariver.com /pages/lamin.htm   (425 words)

  
 Interactive Fly, Drosophila
Lamin is expressed constitutively, in contrast to the second Drosophila lamin, Lamin C, which is developmentally regulated (Riemer, 1995).
Lamins are the major structural proteins of the nuclear lamina, a structure that lines the nucleoplasmic surface of the inner nuclear membrane in higher eukaryotic cells.
Lamins Dm1 and Dm2 are present as a random mixture of homo- and heterodimers.
www.sdbonline.org /fly/polycomb/lamin1.htm   (1459 words)

  
 Bioreagents.com: Lamin A/C
Figure 2 shows a Western blot of lamin A/C from HeLa cell extract using MA3-1000.
Lamins are a class of intermediate filament proteins that form a matrix on the inner surface of the nuclear envelope.
Lamins A and C are alternatively spliced versions of the LMNA gene.
www.bioreagents.com /index.cfm/fuseaction/products.detail/CatNbr/MA3-1000   (234 words)

  
 Interactive Fly, Drosophila
Lamin C is completely absent from the nuclear envelope in mutant primary MEFs, and there is an increase in lamin-C-reactive peptides in the cytoplasm, an observation not seen in wild-type cells when stained with the same antibody.
Lamin B of permeabilized sea urchin sperm nuclei incubated in fertilized egg G1 phase cytosolic extract is phosphorylated within 1 min of incubation and solubilized prior to sperm chromatin decondensation.
Egg vesicles absorbed with lamin isoform-specific antibodies to magnetic beads indicate that lamin LI-associated egg membranes are of heterogenous morphology, and are independent from the lamin LII and LIII vesicle populations.
www.sdbonline.org /fly/polycomb/lamin2.htm   (6521 words)

  
 Discovery of gene for premature aging syndrome reported in Science
The mutation Lévy and his colleagues discovered occurs in the LMNA gene, which contains the "blueprints" for constructing two proteins, called Lamin A and Lamin C. Together with Lamin B, these proteins are woven into a wallpaper-like meshwork, lining the inside of the membrane around the cell's nucleus.
Cells with defective lamin proteins divide improperly and die prematurely, impairing tissues' ability to regenerate.
Disorders caused by defective lamin proteins are collectively known as laminopathies.
www.eurekalert.org /pub_releases/2003-04/aaft-dog041103.php   (841 words)

  
 Decreased and aberrant nuclear lamin expression in gastrointestinal tract neoplasms -- Moss et al. 45 (5): 723 -- Gut
Lamin B1 is encoded by a gene on chromosome 5q23.2-31.3.
Lamins A and C are not expressed at early stages of human lymphocyte differentiation.
Lamins A and C appear during retinoic acid-induced differentiation of mouse embryonal carcinoma cells.
gut.bmj.com /cgi/content/full/45/5/723   (3374 words)

  
 The Stability of the Nuclear Lamina Polymer Changes with the Composition of Lamin Subtypes According to Their ...
Because lamins A and C are identical except for the last 6 residues of lamin C and the last 98 residues of lamin A, the calculations for lamin C are given separately in parentheses.
A, to affirm that the soluble lamins in the column-binding assay were not undergoing significant self-assembly, they were incubated in the same binding buffer for the same amount of time and at the same concentration used in binding assays (20 µg/ml).
Lamins were overexpressed in 293T cells, and cells were extracted at 54 h with detergent and salt.
www.jbc.org /cgi/content/full/279/41/42811   (5200 words)

  
 Lamin Dana Craft   (Site not responding. Last check: )
Lamin Dana, meaning traditional House in Melanau dialect, is a complex build by the locals in an effort to preserve and conserve Melanau culture.
Contemporary usage: Kiran Lamin Dana (Fruit basket) is woven with natural finish befitted its usage as fruit or bread container.
Lamin Dana Cultural Boutique Lodge had used the Babat for its ceiling and had proven that it can last five years or more.
www.lamindana.com /craft.html   (1680 words)

  
 Lamin A N-terminal phosphorylation is associated with myoblast activation: impairment in Emery-Dreifuss muscular ...
Lamin A N-terminal phosphorylation is associated with myoblast activation: impairment in Emery-Dreifuss muscular dystrophy -- Cenni et al.
Lamin A N-terminal phosphorylation is associated with myoblast activation: impairment in Emery–Dreifuss muscular dystrophy
N-terminus lamin C phosphorylation is modulated with a similar pattern, though a less intense phosphorylated lamin C band is observed in cycling myoblasts.
jmg.bmjjournals.com /cgi/content/full/42/3/214   (4431 words)

  
 Insertional Mutation of the Drosophila Nuclear Lamin Dm0 Gene Results in Defective Nuclear Envelopes, Clustering of ...
supernatants of the monoclonal Drosophila lamin Dm antibodies
by lamin Dm antibodies or DAPI was indistinguishable from that
Lamins A and C bind and assemble at the surface of mitotic chromosomes.
www.jcb.org /cgi/content/full/137/5/1001   (8102 words)

  
 Lamin A/C definition - Medical Dictionary definitions of popular medical terms
Lamin A/C: The lamin family of proteins that make up the nuclear lamina, a matrix of protein located next to the inner nuclear membrane.
Lamin proteins are involved in nuclear stability, chromatin structure and gene expression.
Mutations in the lamin A/C gene lead to a number of diseases: Emery-Dreifuss muscular dystrophy type 2, familial partial lipodystrophy, limb girdle muscular dystrophy type 1B, dilated cardiomyopathy, familial partial lipodystrophy, Charcot-Marie-Tooth disorder type 2B1, mandibuloacral dysplasia, childhood progeria syndrome (Hutchinson-Gilford syndrome) and a subset of Werner syndrome.
www.medterms.com /script/main/art.asp?articlekey=24021   (164 words)

  
 Lamin D. Zykara   (Site not responding. Last check: )
Lamin is part of me, and I am part of Lamin.
Lamin is usually torn by the responsibilities he feels, a situation I have experienced many times in my life.
In a sense, Lamin is an expression of my problems, a symbol of what I am and how I feel.
filer.case.edu /tar9/RS   (372 words)

  
 A novel mutation, Ser143Pro, in the lamin A/C gene is common in finnish patients with familial dilated cardiomyopathy ...
A novel mutation, Ser143Pro, in the lamin A/C gene is common in finnish patients with familial dilated cardiomyopathy -- Kärkkäinen et al.
Lamin A/C is a nuclear intermediate filament that is one of
Mutations in the LMNA gene encoding lamin A/C. Hum.
eurheartj.oxfordjournals.org /cgi/content/full/25/10/885   (4170 words)

  
 The lamin CxxM motif promotes nuclear membrane growth -- Prüfert et al. 117 (25): 6105 -- Journal of Cell Science
Lamin antibodies specific for lamins A (antibody X94; A',C'), B2 (antibody X223; B',D') and Drosophila lamin Dm0 (mixture of antibodies ADL195 and ADL84; E') were used.
(E) Drosophila lamin C forms membrane-free electron-dense aggregates at the nuclear envelope (arrow) and in the nucleoplasm (arrowhead) that have a banded substructure when sectioned parallel to the longitudinal axis of the lamin aggregates (inset).
Benavente, R. and Krohne, G. Involvement of nuclear lamins in postmitotic reorganization of chromatin as demonstrated by microinjection of lamin antibodies.
jcs.biologists.org /cgi/content/full/117/25/6105   (6382 words)

  
 Lamin Expression in Human Adipose Cells in Relation to Anatomical Site and Differentiation State -- Lelliott et al. 87 ...
Lamin B1 mRNA is shown after 4 h of autoradiography; lamin A/C and lamin B2 mRNA are shown after 24 h of autoradiography.
to be LMNA (5, 6, 7), the gene encoding A-type nuclear lamins.
B2 is the prevalent B-type lamin, and lamin B1 is absent (40).
jcem.endojournals.org /cgi/content/full/87/2/728   (4766 words)

  
 Meiotic lamin C2: The unique amino-terminal hexapeptide GNAEGR is essential for nuclear envelope association -- ...   (Site not responding. Last check: )
lamin C2 is identical to that of lamin C (28, 29).
Fate of lamin C2 as well as of lamin C2 carrying a mutated amino-terminal hexapeptide as investigated by confocal laser scanning microscopy.
To obtain additional proof as to whether the amino terminus of lamin C2 is myristoylated, COS-7 cells expressing lamin C2 were prepared for two-dimensional gel electrophoresis (37).
www.pnas.org /cgi/content/full/97/24/13120   (4038 words)

  
 Specialty Laboratories ::: we help doctors help patients
Lamin autoantibodies are also associated with antiphospholipid syndrome, autoimmune liver disease, thrombocytopenia and arthralgia, and may be useful in the diagnosis of chronic fatigue syndrome.
The clinical utility of lamin autoantibodies is unknown.
Strong association of autoantibodies to human nuclear lamin B1 with lupus anticoagulant antibodies in systemic lupus erythematosus.
www.specialtylabs.com /books/display.asp?id=68   (265 words)

  
 Properties of lamin A mutants found in Emery-Dreifuss muscular dystrophy, cardiomyopathy and Dunnigan-type partial ...
Endogenous lamin A/C is localized both to the nuclear foci and to the nuclear rim.
A-type lamins, emerin is partly mislocalized to the cytoplasm
of lamin A caused a mislocalization of emerin in the presence
jcs.biologists.org /cgi/content/full/114/24/4435   (7012 words)

  
 Lamin Optical Disc Offset Printer Film Registration Template
Lamin Optical Disc Offset Printer Film Registration Template
Lamin uses a single stainless steel plate for film registration providing consistant, extremely accurate film registration.
HW-430 I Lamin Company Profile I Printer Stucture I Non Stop I/O Handling I Precision Servo Motor I Blanket Roller
www.laminusa.com /film-registration.htm   (82 words)

  
 High-pressure decorative laminates, surfacing material and pre-finished wood veneers: Lamin-Art
High-pressure decorative laminates, surfacing material and pre-finished wood veneers: Lamin-Art
Our design-statement high-pressure decorative laminates and high-performance real wood veneers have been specified and installed in distinctive commercial interior projects worldwide for over 50 years.
Come see Lamin-Art at the Color and Materials Specifiers Conference in New York City on October 30, 2007.
www.laminart.com   (106 words)

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