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	Lap-Chee Tsui - Wikipedia, the free encyclopedia
		Professor Lap-chee Tsui O.Ont. (徐立之 pinyin: Xú Lìzhī; born December 21, 1950) was appointed Vice-Chancellor of the University of Hong Kong in May 2002 and assumed office as the fourteenth Vice-Chancellor of the university with effect from September 1, 2002.
		Tsui was awarded his bachelor's (with only 3rd class honours) and master's degrees from The Chinese University of Hong Kong in 1972 and 1974, respectively.
		Tsui became internationally acclaimed in 1989 when he and his team identified the defective gene, namely Cystic Fibrosis Transmembrane Regulator (CFTR), that causes cystic fibrosis, which is a major breakthrough in human genetics.
	en.wikipedia.org /wiki/Lap-Chee_Tsui (350 words)

	Lap-chee Tsui: Scientific sleuth sets new target
		Tsui, who set himself the goal of learning about the human genome, trained briefly after graduation in the Biology Division of Oak Ridge National Laboratory of Canada, studying the biology of the RNA tumour virus.
		Tsui explained that, as the genes of a monkey and a human are almost identical, varying by only about 2 per cent, the great difference in the two animals has to do with the way an organism controls which genetic instructions are read from its DNA.
		Tsui's role in fostering international collaborations was given more play when he was appointed vice-chancellor of the 92-year-old University of Hong Kong last year.
	mpelembe.mappibiz.com /archives/Lap-chee_Tsui.html (1464 words)

	provost - Professor Lap-Chee Tsui (Site not responding. Last check: 2007-10-09)
		Tsui was born in Shanghai, raised and educated in Hong Kong, and there awarded his bachelor and master degrees from the Chinese University.
		Tsui's achievement was named in the Science magazine as "the most refreshing scientific development of 1989" and hailed in Maclean's Honor Roll as "discoveries of hope at the heart of human life" in the same year.
		Tsui is a key member of the Canadian Genetic Disease Network, which is part of the nation-wide Network of Centers of Excellence funded directly by the federal government to promote the transfer of research findings to commercial applications.
	www.provost.utoronto.ca /English/Professor-Lap-Chee-Tsui.html (764 words)

	Tsui, Lap-Chee
		In 1987 Tsui and Francis Collins of the U of Michigan Medical School - an expert in the chromosome-jumping technique needed in the search for the gene - agreed to work together.
		Two years later, in Aug 1989, Tsui, his Canadian collaborators Jack Riordan and Manuel Buchwald, and Collins with his American research team, announced their successful isolation of the gene carrying the defect that causes cystic fibrosis.
		In 1990 Tsui, Riordan and Collins were awarded the Gairdner Prize for their achievement.
	www.thecanadianencyclopedia.com /index.cfm?PgNm=TCE&Params=A1ARTA0010056 (227 words)

	The Killam Trusts (Site not responding. Last check: 2007-10-09)
		Geneticist Lap-Chee Tsui is best known for his ground-breaking research into cystic fibrosis, a fatal inherited disorder that affects one in 2,500 Caucasian children throughout the world.
		Tsui’s team has continued to be in the forefront of scientific discovery.
		This project has generated many breakthroughs by Dr. Tsui’s team and by the over 50 national and international groups who have collaborated with them in the identification of genes that cause a variety of diseases on chromosome 7.
	www.killamtrusts.ca /english/canadacouncil/tsui.html (276 words)

	University of Hong Kong - Wikipedia, the free encyclopedia
		Lap-Chee Tsui as the new head of the University in 2002.
		Tsui Building were added to the old building to form the University Museum and Art Gallery.
		The Vice-Chancellor is Professor Dr Lap-Chee Tsui, the Deputy Vice Chancellor is Professor R. Wong, and the Pro-Vice-Chancellors are Professor C. Lee, Professor J. Malpas, Professor J. Lee and Professor P. Tam.
	en.wikipedia.org /wiki/University_of_Hong_Kong (3240 words)

	Lap-Chee Tsui (Site not responding. Last check: 2007-10-09)
		Tsui is particularly interested in the organization of large blocks (>100 kb) of duplicated sequences on this chromosome as they appear to be involved in frequent chromosome rearrangements.
		He is also interested in developing mouse models to understand the molecular basis of Williams syndrome, a multisystem disorder caused by the deletion of a segment of this chromosome as well as the pathophysiology of the late-onset form of citrullinemia.
		Crackower MA, Motoyama J, Tsui L-C (1998) Defect in the maintenance of the apical ectodermal ridge in the Dactylaplasia mouse.
	www.genet.sickkids.on.ca /~lapchee (1320 words)

	The University of Texas at Dallas
		Tsui has made his life work defining the genetic defects that causes this inherited disease that affects mainly the lungs and the digestive system to develop better therapies and, perhaps one day, a cure.
		Tsui is geneticist-in-chief and head of the Genetics and Genomic Biology Program of the Research Institute at the Hospital for Sick Children in Toronto.
		Tsui’s visit is sponsored by UTD’s Office of the Vice President of Research and Graduate Education, the University of Texas Southwestern Medical Center at Dallas, the Collin County Comissioners and the UTD chapter of Sigma Xi, an international research society.
	www.utdallas.edu /news/archive/2001/tsui.html (477 words)

	LAP-CHEE TSUI (Site not responding. Last check: 2007-10-09)
		Professor Lap-chee Tsui was appointed Vice-Chancellor of the University of Hong Kong in May 2002 and assumed office as the fourteenth Vice-Chancellor of the university with effect from September 1, 2002.
		Prof Tsui was awarded his bachelor and master's degrees from The Chinese University of Hong Kong in 1972 and 1974, respectively.
		Prof Tsui was born in Shanghai on December 21, 1950.
	www.websters-online-dictionary.org /definition/LAP-CHEE+TSUI (281 words)

	wikien.info: Main_Page (Site not responding. Last check: 2007-10-09)
		Antique lap desk As an antique the lap desk is a smaller variant of the writing slope.
		A lap dog gets its name from its size; it is small enough to be held in the arms or lie comfortably on a person's lap.
		Lap Steel Guitar (also called Hawaiian Guitar or simply lap steel or steel guitar) is a type of guitar, and a method of playing the instrument.
	teknoworld.info /browse.php?title=L/LA/LAP (6866 words)

	CaSSS: Industry News
		Tsui said the team's complete sequence, like its initial sequence, would be available publicly.
		Tsui also said China was actively involved in the human genome projects in hopes of finding answers to treatment of common ailments found in the country.
		Tsui said Chinese scientists were also delving into plant genetics and bio-engineering research to improve the quality of its key crops such as rice, widely regarded as a basis for studying other grains.
	www.casss.org /news/2002/2002APR15B.htm (389 words)

	Lap-Chee Tsui Biography / Biography of Lap-Chee Tsui World of Genetics Biography
		Tsui's career continued to flourish; he holds the Sellers Chair of Cystic Fibrosis Research, and in 1996 he became the hospital's Geneticist-in-Chief.
		Tsui is a Professor of Molecular and Medical Genetics at the University of Toronto.
		Tsui's contribution to science, to his adopted country, and to international relations have all been appropriately recognized by awards far too numerous to list.
	www.bookrags.com /biography-lap-chee-tsui-wog (684 words)

	Hong Kong Association of Southern California
		Education is the key to economic success, and Tsui believed that Hong Kong is prepared to assume the role of an international education hub.
		However, Tsui pointed out that educators must bear in mind the development of human capital potential and consider the fact that university graduates today will likely enter and pursue several careers, and that employers today seek attributes such as pragmatism, logical thinking and communication skills.
		Tsui sees the future of higher education in research that will contribute to regional development.
	www.hkasc.org /hongkongfocus_LapCheeTsui.htm (757 words)

	science.ca Profile : Lap-Chee Tsui (Site not responding. Last check: 2007-10-09)
		Now show me that it’s real.” Tsui doesn’t seem excited at all but he knows this is a solid clue, a major hint that they have found what they are looking for: the gene for cystic fibrosis, and the cause of that terrible disease.
		Lap Chee Tsui is particularly interested in the gene for cystic fibrosis and other genes on human chromosome number 7.
		Over the years, Tsui and his team have discovered that the DNA sequence with the mutation was part of the instructions for making a special protein called CFTR (Cystic Fibrosis Transmembrane conductance Regulator), a part of the cell membrane in certain special epithelial (surface) cells that generate mucous.
	www.science.ca /scientists/scientistprofile.php?pID=19 (1630 words)

	Lap-Chee Tsui - Nature Medicine
		Born in Shangai, Tsui obtained his Bachelor's and Master's degrees from the Chinese University of Hong Kong before leaving to pursue a PhD at the University of Pittsburgh.
		Tsui's plans to continue to work on CF at his Toronto laboratory for at least three more years when he moves to Hong Kong, although his other major research focus—an effort to construct an integrated physical and genetic map of chromosome 7—will continue in the laboratory of his colleague and former trainee Steve Scherer.
		Tsui's first attempt to "cultivate the collaborative spirit" is going to be through the establishment of a genome research center at the University of Hong Kong, which will bring together researchers and resources from within the university and other institutes in the Hong Kong region.
	www.nature.com /nm/journal/v8/n9/full/nm0902-910.html (992 words)

	The Canadian Club of Toronto (Site not responding. Last check: 2007-10-09)
		Born in Shanghai, educated in Hong Kong and the USA, Professor Tsui spent 20 years in Canada, most of it, at the Hospital for Sick Children where he was Geneticist-in-Chief and Head of the Genetics and Genomic Biology Program of the Research Institute.
		Professor Tsui joined HKU in 2002, bringing to the role of Vice-Chancellor, his experience as a researcher, teacher and an internationally renowned geneticist in his own right, having led the discovery of the gene that causes cystic fibrosis.
		Professor Tsui will join us on October 29th to share his thoughts on the changing educational landscape in Hong Kong and more broadly across China and what this means for countries like Canada, who currently have a large number of Asian students pursuing higher education here.
	www.canadianclub.org /index.cfm?action=event&ID=2967 (327 words)

	Page Title (Site not responding. Last check: 2007-10-09)
		Lap-Chee Tsui and Jack Riordan, in collaboration with Dr. Francis Collins announced the discovery of the gene responsible for cystic fibrosis.
		Cystic fibrosis is an inherited genetic disease in humans, which affects the cells of various glands -including mucus-secreting glands and sweat glands in the skin (epithelial glands)(9).
		The cystic fibrosis gene was discovered in humans in August 1989(10) by Lao Chee Tsui, a Canadian genetisist(11).
	www.linkny.com /~civitas/page357.html (1264 words)

	Lap-Chee Tsui
		Tsui was awarded his bachelor and master's degrees from The Chinese University of Hong Kong in 1972 and 1974, respectively.
		He received his Ph.D. degree from the University of Pittsburgh in 1979.
		Tsui became internationally acclaimed in 1989 when he and his team identified the detective gene, namely Cystic Fibrosis Transmembrane Regulator (CFTR), that causes cystic fibrosis, which is a major breakthrough in human genetics.
	www.sciencedaily.com /encyclopedia/lap_chee_tsui (334 words)

	Lap-Chee Tsui - Encyclopedia Glossary Meaning Explanation Lap-Chee Tsui (Site not responding. Last check: 2007-10-09)
		Lap-Chee Tsui - Encyclopedia Glossary Meaning Explanation Lap-Chee Tsui.
		Professor Lap-chee Tsui (徐立之 born December 21, 1950) was appointed Vice-Chancellor of the University of Hong Kong in May 2002 and assumed office as the fourteenth Vice-Chancellor of the university with effect from September 1, 2002.
		Tsui was awarded his bachelor's (with 3rd honours) and master's degrees from The Chinese University of Hong Kong in 1972 and 1974, respectively.
	www.encyclopedia-glossary.com /en/Lap-Chee-Tsui.html (333 words)

	National Academy of Sciences - Members (Site not responding. Last check: 2007-10-09)
		From Canada, Tsui has made major contributions to the mapping, cloning, and detailed characterization of the human gene that is mutated in cystic fibrosis.
		He has also contributed to the mapping and annotation of human chromosome 7, and to the identification of other disease genes.
		The goal of the latter project has been to generate an integrated genetic, physical and transcriptional map for this chromosome to facilitate identification of other disease genes.
	www4.nationalacademies.org /nas/naspub.nsf/(urllinks)/NAS-5YKFAB?opendocument (251 words)

	[No title] (Site not responding. Last check: 2007-10-09)
		Heng, H.H.Q., Shi, X-M., and Tsui, L-C. Fluorescence in situ hybridization mapping of the cystic fibrosis transmembrane conductance regulator (CFTR) gene to 7q31.3.
		Heng, H.H.Q., Xie, B., Shi, X-M., Tsui, L-C., and Mahuran, D. Refined mapping of the Gm2 activator protein (GM2A) locus to 5q31.3-q33.1, distal to the spinal muscular atrophy locus.
		Scherer, S.W., Heng, H.H.Q., Mahon, K.A., Evans, J., and Tsui, L-C. Assignment of the human homolog of mouse DIX-3 to chromosome 17q21-q22 by analysis of somatic cell hybrids and fluorescent in situ hybridization.
	www.genet.sickkids.on.ca /~henry/cv.html (2132 words)

	CCFF: CF research & clinical care: highlights of progress (Site not responding. Last check: 2007-10-09)
		Lap-Chee Tsui and Manuel Buchwald trace the gene responsible for CF to chromosome 7.
		Lap-Chee Tsui and Jack Riordan of the RDP I team, in collaboration with Dr.Francis Collins, announce the discovery of the gene responsible for cystic fibrosis.
		In 2002, Genome Canada awarded Dr. Lap-Chee Tsui (The Hospital for Sick Children) and his colleagues $3.36 million over 3 years to supplement CCFF research funds (for a total grant of $7.01 million) to help researchers identify and understand the role of modifier genes in individuals with CF.
	www.cysticfibrosis.ca /page.asp?id=82 (2607 words)

	WritingDEN: Paragraphs - 1 of 3 (Site not responding. Last check: 2007-10-09)
		In July 1989, Dr. Lap-Chee Tsui and a team of scientists working at the Hospital for Sick Children in Toronto achieved a major scientific breakthrough.
		Tsui and his colleagues discovered the gene that causes cystic fibrosis (CF).
		They may be right because the results of Tsui’s work have helped scientists develop tests that identify carriers of the CF gene.
	www2.actden.com /writ_Den/t04/Level3/page1.htm (95 words)

	Scotsman.com News - Sci-Tech - Scientists race ahead in genome mapping (Site not responding. Last check: 2007-10-09)
		Lap-Chee Tsui, the president of the Human Genome Organisation (HUGO), said the breakthrough was destined to turn medicine on its head.
		London-based HUGO is the largest international non-profit organisation involved in human genome research and consists of a consortium of scientists from the United States, Britain, Japan, France, Germany and China.
		Prof Tsui also said China was actively involved in the human genome projects in the hope of finding answers for a number of common ailments found in the country.
	news.scotsman.com /scitech.cfm?id=401112002 (630 words)

	BBC News \| SCI/TECH \| Gene knowledge gap
		Professor Lap-Chee Tsui, outgoing president of the meeting's organiser (Human Genome Organisation - Hugo), says that our poor understanding of even basic human anatomy means that the human genome project is not delivering cures for genetic diseases as was hoped.
		Professor Lap-Chee Tsui, from Montreal University, says the genome can be used in studying infectious diseases.
		Professor Tsui said he hoped that by the time of next year's meeting, scientists would have developed many practical applications from the data.
	news.bbc.co.uk /hi/english/sci/tech/newsid_1935000/1935320.stm (470 words)

	ETIC Main Page
		Professor Tsui was appointed Vice-Chancellor of the University of Hong Kong in May 2002 and has assumed office as the fourteenth Vice-Chancellor of the University with effect from September 1, 2002.
		Prior to his appointment, Professor Tsui was Geneticist-in-Chief and Head of the Genetics and Genomic Biology Program of the Research Institute, at The Hospital for Sick Children in Toronto.
		While Professor Tsui's current research continues towards a better understanding of cystic fibrosis, he is also active in other genetic and disease gene analysis.
	www.etic.com.hk /company_bod.jsp (1688 words)

	china11 (Site not responding. Last check: 2007-10-09)
		Lap-Chee Tsui, O.C., was born in Shanghai, China, 1950.
		In 1989, Dr. Tsui attracted international attention when he announced that he and colleagues had identified the defective gene responsible for cystic fibrosis.
		Recipient of four honorary doctorates, Dr. Tsui is the inaugural holder of the H.E. Sellers Chair in Cystic Fibrosis at The Hospital for Sick Children.
	collections.ic.gc.ca /heirloom_seven/volume7/countries/china11.html (237 words)

	Cystic Fibrosis (Site not responding. Last check: 2007-10-09)
		Approximately 1 in 25 people in the United States carry such a mutation, but because the disease is recessive, in most cases both parents must carry a mutation in the gene in order for their children to be affected.
		Based on the DNA sequence of the CF gene, Collins, Tsui and Riordan predicted that the protein it encodes sits in a cell's outer membrane, where it serves as a tiny pore, or channel, through which charged atoms called ions move into or out of the cell.
		The researchers suggested that the protein might be a channel for chloride ions because cells from people with CF had been shown to have faulty chloride ion transport.
	www.hhmi.org /annual99/a211.html (340 words)

	The Human Genome Organisation
		He was awarded to "Chevalier" from France Government in August 2001, in recognition of his contribution to the scientific co-operation between France and Japan.
		Professor Lap-Chee Tsui is Vice-Chancellor of the University of Hong Kong.
		Prior to his present appointment in September 2002, Professor Tsui was Geneticist-in-Chief and Head of the Genetics and Genomic Biology Program of the Research Institute, at The Hospital for Sick Children in Toronto.
	www.hugo-international.org /mission_presidents.htm (1881 words)

	Neuro, Spring 2000 (Site not responding. Last check: 2007-10-09)
		The international effort is coordinated by HUGO (Human Genome Organization), whose current president is Dr. Lap-Chee Tsui, Geneticist in Chief at Toronto's Hospital for Sick Children.
		In 1989, Dr. Lap-Chee Tsui, Geneticist-in-Chief at Toronto's Hospital for Sick Children, led the team that discovered the gene that is altered in cystic fibrosis (CF).
		For Dr. Tsui, one of the major benefits of human genomics research is the ability to study complex diseases such as diabetes and asthma, and multi-gene diseases such as Williams syndrome and many cancers, diseases that they were unable to really get a handle on before.
	www.mni.mcgill.ca /nm/2000se/nm2000se_p8.htm (873 words)

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