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Topic: Lassa virus

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	Lassa Fever \| CDC Special Pathogens Branch
		Lassa fever is an acute viral illness that occurs in West Africa.
		The virus, a member of the virus family Arenaviridae, is a single-stranded RNA virus and is zoonotic, or animal-borne.
		Lassa fever is an endemic disease in portions of West Africa.
	www.cdc.gov /ncidod/dvrd/spb/mnpages/dispages/lassaf.htm (1214 words)

	Lassa Fever
		Lassa virus was first described in Lassa, a village of northern Nigeria, in the central region of Africa.
		In this rodent, Lassa causes a chronic, inapparent infection with persistent viremia.
		Producing a Lassa vaccine is not a priority for the centre, as outbreaks of the virus have been restricted to a relatively small area.
	library.thinkquest.org /26215/lassa.html (1165 words)

	MedNets : A medical search engine and health portal
		Lassa fever is an acute viral illness that occurs in West Africa.
		The virus, a member of the virus family Arenaviridae, is a single-stranded RNA virus and is zoonotic, or animal-borne.
		Lassa fever is an endemic disease in portions of West Africa.
	www.mednets.com /index.cfm/fuseaction/articles_lassa_fever_lassa (1248 words)

	Lassa Fever Virus
		Lassa virus is a member of the Old World Arenaviruses, and, as such, is endemic in Western Africa.
		Lassa virus is typically spread through aerosolized virus particles, via either infected rodents (Mastomys natalensis) or close contact with infected individuals.
		Lassa virus is easily isolated from the blood during the febrile stage of the illness, and CF, IFA, and ELISA may all be used for detecting viral antibodies.
	www.stanford.edu /group/virus/arena/2005/LassaFeverVirus.htm (703 words)

	Sierra Leone: Lassa fever outbreak
		Lassa fever is an acute viral illness transmitted by rats that is common in West Africa.
		Lassa fever is caused by a virus known as Lassa virus.
		Lassa fever spreads by human to human contact, transmission occurring through contact with an infected person's blood, tissue, secretions, or excretions of an individual infected with the Lassa virus.
	www.scienceinafrica.co.za /2003/october/lassa.htm (587 words)

	Lassa Fever (Site not responding. Last check: 2007-11-03)
		Lassa fever is a viral infection caused by the Lassa virus.
		As the virus is present in bodily secretions such as urine, saliva, and semen, it can be spread through sexual contact as well.
		Hospitals and dispensaries are ideal environments for the spread of Lassa, and the worst epidemics documented have occurred in these places.
	www.thirdworldtraveler.com /Disease/lassa_fever.html (315 words)

	lassa
		TRANSMISSION The Lassa virus is transmitted by inhalation of aerosolized rodent droppings (12), indirect contact with fomites or ingestion of food contaminated with rodent droppings or urine, or by eating the rats themselves (3).
		The virus is shed is the urine of Lassa patients for anywhere from 3 to 9 weeks after the illness begins and in semen for up to 3 months (6).
		Lassa virus can also be cultured in VERO cells and their presence demonstrated by immunofluorescence (5).
	www2.austincc.edu /microbio/2704f/lassa.htm (1586 words)

	Medmicro Chapter 57 (Site not responding. Last check: 2007-11-03)
		The virus is round, oval, or pleomorphic, 110 to 130 nm in diameter, and enveloped.
		Virus can be recovered from the blood and serum for up to 3 weeks after onset of the infection, and Lassa virus can be recovered from the urine for up to 5 weeks.
		Lassa virus is regularly isolated by inoculation of Vero cells.
	gsbs.utmb.edu /microbook/ch057.htm (2817 words)

	HaemorrhagicFever
		Lassa fever is a well-recognized nosocomial infection e.g.
		The rodent C callosus is the reservoir for Macupo virus in an endemic region in Bolivia encompassing a population of 50,000.
		Virological diagnosis is readily achieved by virus isolation from serum during the febrile phase of the illness.
	virology-online.com /viruses/HaemorrhagicFever.htm (1870 words)

	Lassa Fever
		This virus results in a 30% fatality rate in pregnant women and is 95% lethal to a fetus in the third trimester.
		The reservoir for the virus is the multimammate rat.
		Since the rat sheds the virus in its urine and fecal material, this is the source of the virus' primary transmission to humans.
	www.arches.uga.edu /~icund/Lassa_Fever.html (298 words)

	lassa
		The virus was traced back to the town of Lassa, for which it was named (1).
		Lassa virus is of the arenaviridae family (1).
		The greatest amount of the virus are found in the spleen, lymph nodes, and bone marrow.
	www.austincc.edu /microbio/2704l/lassa.htm (617 words)

	WHO \| Lassa fever
		Lassa viral haemorrhagic fever is an acute illness of 1-4 weeks duration that occurs in West Africa.
		The virus is a single-stranded RNA virus belonging to the virus family Arenaviridae.
		The animal reservoir, or host, of Lassa virus is a rodent of the genus Mastomys, commonly known as the “multimammate rat.” Mastomys infected with Lassa virus do not become ill, but they can shed the virus in their excreta (urine and faeces).
	www.who.int /mediacentre/factsheets/fs179/en (944 words)

	Lassa Fever: Description, Vector, Mechanism, Symptoms, Mortality Rates, and so on...
		Lassa fever, an arenavirus, is an enveloped, single-stranded, bisegmented RNA virus.
		Lassa fever is named after the town (in the Yedseram River valley) in which the first cases were isolated in 1969, during a nosocomial outbreak at a local hospital.
		Lassa virus has been isolated from semen 6 weeks after acute illness; the virus can be transmitted to sexual partners by convalescent men.
	www.tarakharper.com /v_lassa.htm (1663 words)

	24DrTravel.com Reference Library - Lassa Fever
		Lassa fever is an acute viral illness of one to four weeks duration caused by Lassa virus, a member of the arenavirus family of viruses.
		Lassa infection in rodents persists and the virus is shed throughout the life of the animal.
		The virus may be excreted in the urine of patients for three to nine weeks from the onset of illness.
	www.24drtravel.com /reference/library/travel/lassa_fever.asp (1101 words)

	Ebola Virus Haemorrhagic Fever
		The results of the Lassa virus CF antibody tests on Mastomys natalensis sera are shown in Table 1: 56 sera from other rodent species from the same localities: Tatera, Myomys, Rattus, Arvicathus, Lemniscomys, the hedgehog, Erinaceus, and shrew, Crocidura were negative for Lassa CF antibodies.
		On the other hand, during the 1974 Lassa outbreak in Onitsha, Anambra State, none of the human and animal sera tested was positive for Lassa CF antibodies, although 3 cases of Lassa fever infection were confirmed by virus isolation and/or antibody studies (12).
		The Pankshin area of the Plateau State may be considered a highly endemic zone for Lassa fever in the state, as evidenced by the high level of antibodies in humans and Mastomys, as well as the high rate of virus isolation from Mastomys in that area.
	www.itg.be /ebola/ebola-49.htm (1660 words)

	UNSW Embryo- Abnormal Development - Lassa virus
		Lassa virus is a member of the virus family Arenaviridae, a single-stranded RNA virus.
		The virus is the causative agent of a hemorrhagic fever and can be transmitted between species (zoonotic).
		These effects can be directly by virus crossing the placental barrier and infecting the developing embryo, or indirectly due to the impact on the mother, for example the effects of fever.
	embryology.med.unsw.edu.au /Defect/lassavirus.htm (488 words)

	Lassa fever - lassa fever virus
		The virus belongs to Arenaviridae family; it is an enveloped, single-stranded, bisegmented RNA virus.
		Lassa fever is less deadly compared to ebola, though they share similar symptoms.
		All persons suspected of Lassa fever infection should be admitted to isolation facilities and their body lassa fever fluids and excreta properly disposed of.
	www.medicalgeo.com /Med-Diseases-L/Lassa-fever.html (1120 words)

	Replicon System for Lassa Virus -- Hass et al. 78 (24): 13793 -- The Journal of Virology
		Lassa fever is the broad-spectrum nucleoside analogue ribavirin
		Sequence heterogeneity in the termini of lymphocytic choriomeningitis virus genomic and antigenomic RNAs.
		Lassa virus Z protein is a matrix protein sufficient for the release of virus-like particles.
	jvi.asm.org /cgi/content/full/78/24/13793 (8272 words)

	Lassa fever - WrongDiagnosis.com
		Lassa fever is an acute viral hemorrhagic fever first described in 1969 in the Nigerian town of Lassa in the Yedseram River valley.
		With a diagnosis of Lassa fever, it is also important to consider whether there is an underlying condition causing Lassa fever.
		The prognosis of Lassa fever may include the duration of Lassa fever, chances of complications of Lassa fever, probable outcomes, prospects for recovery, recovery period for Lassa fever, survival rates, death rates, and other outcome possibilities in the overall prognosis of Lassa fever.
	www.wrongdiagnosis.com /l/lassa_fever/intro.htm (676 words)

	Lassa fever: essential data
		The virus is spread throughout western Africa, although not all isolates have been associated with outbreaks of the disease.
		Infection is thought to occur by inhaling virus in dust after it has been deposited in the urine of a carrier animal.
		In areas where the disease is endemic, 15-40% of the population have circulating antibodies to the virus that appear to be as a result of asymptomatic or low-grade infections.
	www.cbwinfo.com /Biological/Pathogens/LASV.html (504 words)

	Lassa Fever Virus (Site not responding. Last check: 2007-11-03)
		The focus of this report will be on Lassa Fever Virus, a Level 4 virus belonging to the family Arenaviridae.
		Lassa is found primarily in West Africa where it is classified as an endemic virus.
		Little did you know that Lassa Fever Virus, named after the town you resided in as a missionary, was to become one of the most widely spread hemorrhagic fevers in about 30 years and still be without a vaccine.
	www.geocities.com /guipago_22/Virology.html (367 words)

	eMedicine - CBRNE - Viral Hemorrhagic Fevers : Article by David C Pigott, MD (Site not responding. Last check: 2007-11-03)
		Lassa virus is the most clinically significant of the Arenaviridae, accounting for serious morbidity and mortality in West Africa.
		RVF virus, an important African pathogen, is transmitted to humans and livestock by mosquitos and by the slaughter of infected livestock.
		Apodemus agrarius, the vector of Korean hemorrhagic fever caused by a hantavirus.
	www.emedicine.com /emerg/topic887.htm (3747 words)

	ScienceDaily: Experimental Vaccine Protects Nonhuman Primates From Lassa Fever
		Lassa fever is common in parts of West Africa where it causes a significant amount of death and disability among the population.
		The Lassa virus that causes the disease is considered a potential agent of bioterrorism.
		West Nile virus -- West Nile virus is a virus of the family Flaviviridae, found in both tropical and temperate regions.The main route of human infection is through the bite of an infected...
	www.sciencedaily.com /releases/2005/06/050627232941.htm (2079 words)

	eMedicine - Arenaviruses : Article by Larry I Lutwick, MD
		Lassa virus (ie, Lassa fever): Lassa fever is endemic to West Africa.
		Lassa virus can be isolated easily (ie, in a biosafety level 4 laboratory) in tissue culture using the E6 clone of Vero cells or in suckling mice.
		In one study with Lassa virus, a recombinant vaccinia virus that expressed Lassa virus glycoprotein was found to be efficacious in primates.
	www.emedicine.com /med/topic166.htm (3531 words)

	00.003.0.01.003. Lassa virus
		Virus belongs to the serogroup (or complex) LCM-LASV Complex (Old world arenaviruses).(VC 00.003.0.01.
		ICTV members and experts, or by the ICTVdB Management using data provided by the experts, the literature or the latest ICTV Report.
		All virus descriptions are based on the character list and natural language translations from the encoded descriptions are automatically generated and formatted for display on the Web.
	www.ncbi.nlm.nih.gov /ICTVdb/ICTVdB/03011003.htm (339 words)

	Lassa fever - Wikipedia, the free encyclopedia
		In fatal cases, Lassa fever is characterized by impaired or delayed cellular immunity leading to fulminant viremia.
		Lassa fever is far less deadly compared to Ebola, though they share similar symptoms.
		Clinically, Lassa fever infections are difficult to distinguish from other viral hemorrhagic fevers such as Ebola and Marburg, and from more common febrile illnesses such as malaria.
	en.wikipedia.org /wiki/Lassa_fever (1186 words)

	BBC NEWS \| Health \| Lassa fever vaccine shows promise
		Lassa fever is endemic in West Africa, where hundreds of thousands of people are infected each year.
		The virus is transmitted to humans from rodents that harbour the virus.
		Lassa vaccine initiatives have suffered from a lack of funding in the past.
	news.bbc.co.uk /go/rss/-/2/hi/health/4626637.stm (521 words)

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