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Topic: Lennox-Gastaut syndrome


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In the News (Tue 22 Dec 09)

  
 Lennox-Gastaut syndrome - Wikipedia, the free encyclopedia
Lennox-Gastaut syndrome (LGS), also known as Lennox syndrome, is a difficult to treat form of childhood-onset epilepsy, that most often appears between the second and sixth year of life and is characterized by frequent seizures and different seizure types and is often accompanied by mental retardation and behavior problems.
(1993) Efficacy of Felbamate in Childhood Epileptic Encephalopathy (Lennox-Gastaut Syndrome).
Gamma-vinyl-GABA (vigabatrin) in the therapy of Lennox-Gastaut syndrome: an open study.
en.wikipedia.org /wiki/Lennox-Gastaut_syndrome   (1338 words)

  
 Syndrome, Lennox-Gastaut definition - Medical Dictionary definitions of popular medical terms
Syndrome, Lennox-Gastaut: A severe form of epilepsy that usually begins in early childhood and is characterized by frequent seizures of multiple types, mental impairment, and a particular brain wave pattern (a slow spike-and-wave pattern).
The Lennox-Gastaut syndrome usually develops in children between 1 and 8 years of age and is characterized by seizures, developmental delay, and behavioral disturbances such as poor social skills and attention-seeking behavior.
The syndrome is named for W.G. Lennox and H. Gastaut who described it.
www.medterms.com /script/main/art.asp?articlekey=5647   (354 words)

  
 Epilepsy Action: Lennox-Gastaut Syndrome
Lennox-Gastaut syndrome does not usually run in families and the numbers of children affected is not known with certainty but it may account for some 10 per cent of all childhood epilepsies, and for up to 50 per cent of childhood epilepsies that do not respond to anti-epileptic drug treatment.
The Lennox-Gastaut syndrome is one of the hardest forms of childhood epilepsy to treat.
However, a small group of people (5 per cent) with otherwise typical Lennox-Gastaut syndrome grow out of their seizures by the time they are teenagers and subsequently will attain average or near average levels of ability.
www.epilepsy.org.uk /info/lennox.html   (919 words)

  
 Lennox-Gastaut
The Lennox-Gastaut (LG) syndrome is one of the epileptogenic encephalopathies of childhood an it presents as intractable or hard to control seizures.
It is evident, that polypharmacy is the rule in the Lennox-Gastaut syndrome.
The prognosis for patients with the Lennox-Gastaut syndrome is usually poor.
home.coqui.net /myrna/lennox.htm   (810 words)

  
 Special Child: Disorder Zone Archives - Lennox-Gastaut Syndrome
Lennox-Gastaut syndrome (LGS) is one of the most severe forms of childhood epilepsy and is characterized by several different seizure types and developmental delay.
If you are interested in meeting other parents and individuals who are involved in raising a child with Lennox-Gastaut syndrome, the following listserv is available:
In 1938, the classic EEG pattern was identified and in 1950, Dr. Lennox found and described a clinical correlation between the typical EEG pattern and patients with multiple epileptic episodes.
www.specialchild.com /archives/dz-017.html   (3550 words)

  
 Lennox-Gastaut syndrome
Lennox-Gastaut syndrome (LGS) belongs to the group of severe childhood epileptic encephalopathies.
This disorder is defined as a cryptogenic or symptomatic generalized epilepsy, which is characterized by the following symptomatic triad: several epileptic seizures (atypical absences, axial tonic seizures and sudden atonic or myoclonic falls); diffuse slow interictal spike wave in the waking electroencephalogram (EEG) (
www.orpha.net /static/GB/lennoxgastaut_syndrome.html   (56 words)

  
 Lennox-Gastaut Syndrome
Lennox-Gastaut syndrome is a severe form of epilepsy (a seizure disorder).
However, the types of seizures associated with Lennox-Gastaut syndrome are generally difficult to control due to their resistance to most anti-epileptic drugs.
The NINDS conducts and supports a broad program of basic and clinical research on epilepsy including Lennox-Gastaut syndrome.
clevelandclinic.org /health/health-info/docs/1200/1296.asp?index=6036   (390 words)

  
 lennox-gastaut.html
AB: In 102 patients with Lennox-Gastaut syndrome (LGS) observed for an average of 16 years (range, 10-20 years), 12 of the patients worked normally, 36 worked part-time or at a sheltered workshop, and most of the remaining 54 were under home care or institutionalization.
LGS evolved from West syndrome or from unspecified epilepsies, or as the primary form, mostly in childhood and rarely in adolescence or adulthood.
AB: Early infantile epileptic encephalopathy (EIEE) with burst-suppression (Ohtaharas syndrome) is a rare type of epileptic encephalopathy in infancy and represents the earliest type of age-related symptomatic generalised epilepsy.
www.indiana.edu /~pietsch/lennox-gastaut.html   (6003 words)

  
 Lennox-Gastaut Syndrome : Epilepsy.com
Three kinds of seizures that usually occur in Lennox-Gastaut syndrome are tonic, atonic (also known as akinetic), and atypical absence seizures.
But children with Lennox-Gastaut syndrome most often have non-convulsive status epilepticus, which can be very difficult to recognize.
And another parent's view: "The parent of a child with Lennox-Gastaut syndrome needs lots of patience.
www.epilepsy.com /epilepsy/epilepsy_lennoxgastaut.html   (839 words)

  
 Treatment of Lennox-Gastaut syndrome
Lennox-Gastaut syndrome is a seizure (epilepsy) disorder which is commonly associated with behavioural and mental health problems.
The optimum treatment for Lennox-Gastaut syndrome remains uncertain and no study to date has shown any one drug to be highly efficacious; lamotrigine, topiramate and felbamate may be helpful as add-on therapy.
All randomised controlled trials (RCTs) of the administration of drug therapy to patients with Lennox-Gastaut syndrome.
www.cochrane.org /reviews/english/ab003277.html   (548 words)

  
 Lennox-Gastaut syndrome : Epilepsy.com/Professionals
Author: Gregory L. Holmes, MD Lennox-Gastaut syndrome (LGS) is characterized by a mixed seizure disorder.
About Epilepsy & Seizures > Epilepsy Syndromes > Lennox-Gastaut syndrome
Some children with this syndrome have hundreds of seizures daily.
professionals.epilepsy.com /page/syndromes_lennox.html   (838 words)

  
 News - FDA Approves Topamax (Topiramate) As Adjunctive Therapy For Lennox-Gastaut Syndrome
A study of Topamax was conducted at 12 sites, involving 98 patients who had a history of symptoms associated with Lennox-Gastaut Syndrome and had experienced a minimum of 60 seizures during the month before the study started.
Lennox-Gastaut Syndrome (LGS) is one of the most severe forms of epilepsy.
"The results of the study of topiramate in Lennox-Gastaut Syndrome are impressive, given how difficult this condition can be to treat - particularly in young children," says John Pellock, MD, chairman of child neurology at the Medical College of Virginia and one of the investigators in the study.
docguide.com /news/content.nsf/news/5E579F4136CDE07C85256ABD004FE165   (767 words)

  
 ScienceDaily:
Treatment Of Down Syndrome In Mice Restores Nerve Growth In Cerebellum (January 31, 2006) -- Researchers at Johns Hopkins restored the normal growth of specific nerve cells in the cerebellum of mouse models of Down syndrome that were stunted by this genetic condition.
Study Finds Nerve Damage In Previously Mysterious Chronic Pain Syndrome (January 31, 2006) -- Researchers at Massachusetts General Hospital have found the first evidence of a physical abnormality underlying the chronic pain condition called reflex sympathetic dystrophy or complex regional...
Archaeologists Uncover One Of Biggest Medieval Graveyards (January 31, 2006) -- University of Leicester archaeologists are beginning work on examining the largest discovery of medieval skeletons -- numbering 1,300 -- to be found outside London.
www.sciencedaily.com /encyclopedia/list_of_neurological_disorders   (770 words)

  
 Lennox Gastaut Syndrome
Lennox-Gastaut Syndrome may be due to or occur in association with a number of different underlying disorders or conditions.
It is possible that the main title of the report Lennox Gastaut Syndrome is not the name you expected.
The disorder is characterized by frequent episodes of uncontrolled electrical disturbances in the brain (seizures) and, in many cases, abnormal delays in the acquisition of skills that require the coordination of mental and muscular activity (psychomotor retardation).
www.healthnowny.com /kbase/nord/nord887.htm   (383 words)

  
 LENNOX-GASTAUT SYNDROME : Contact a Family - for families with disabled children: information on rare syndromes and disorders
Lennox-Gastaut syndrome is the name given to a group of severe epilepsies which occur in childhood.
LENNOX-GASTAUT SYNDROME : Contact a Family - for families with disabled children: information on rare syndromes and disorders
It sometimes follows the onset of seizures in the first year of life, which may include infantile spasms (see West syndrome).
www.cafamily.org.uk /Direct/l27.html   (717 words)

  
 Lennox-Gastaut syndrome definition - Medical Dictionary definitions of popular medical terms
Lennox-Gastaut syndrome: A severe form of epilepsy that is characterized by the onset in early childhood of frequent seizures of multiple types, developmental delay, a particular brain wave pattern (a slow spike-and-wave pattern), and behavioral disturbances with poor social skills and attention-seeking behavior.
The seizures in this syndrome are notoriously hard to treat and may lead to falls and injuries.
The types of seizures may include tonic (stiffening of the body, upward deviation of the eyes, dilation of the pupils, and altered respiratory patterns), atonic (brief loss of muscle tone and consciousness, causing abrupt falls), atypical absence (staring spells), and myoclonic (sudden muscle jerks).
www.medterms.com /script/main/art.asp?articlekey=4131   (277 words)

  
 lennox-gastaut syndrome & vaccination
Lennox-Gastaut syndrome after a further attenuated live measles vaccination.
A severe form of epilepsy that usually begins in early childhood and is characterised by frequent seizures of multiple types, mental impairment, and a particular brain wave pattern (a slow spike-and-wave pattern)
www.whale.to /vaccines/lennox.html   (41 words)

  
 Lennox-Gastaut Syndrome
If your son has Lenox-Gastuat syndrome, he will probably never have what would be considered good control of his seizures, but may, with continued experimentation with combinations of drugs be able to achieve a reasonable quality of life.
As it is a syndrome, multiple different pathways of brain injury may produce it.
It may be that your son had an immunologic reaction to one of the componenets of the MMR vaccine that damaged his brain.
www.medhelp.org /perl6/neuro/archive/426.html   (644 words)

  
 Vagus Nerve Stimulation May Be Good Treatment Option For Lennox-Gastaut Syndrome
Lennox-Gastaut syndrome is a severe form of epilepsy that most commonly develops in children between the ages of one and eight.
The types of seizures that the Lennox-Gastaut syndrome presents are generally resistant to most antiepileptic drugs, and these drugs frequently contribute to cognitive and behavioral abnormalities.
"Unlike the traditional therapies for Lennox-Gastaut syndrome, VNS presents no serious, harmful side effects, and study results suggest that VNS could be a viable alternative for the thousands of patients who suffer from Lennox-Gastaut syndrome." Dr. Hosain recently presented one-year follow-up results on the study patients at the American Epilepsy Society annual meeting.
www.docguide.com /dg.nsf/PrintPrint/0331629B8FE9710685256A1E004D3007   (684 words)

  
 Lamictal Side Effects - Lamictal Drug Information - Dosage - Drug Interactions - Uses - Storage - Overdose - Precautions - Lamotrigine
Therefore, lamotrigine should only be used in children who have partial seizures or seizures associated with Lennox-Gastaut syndrome.
These rashes (e.g., Stevens-Johnson syndrome) are more common in children (less than 16 years old) than in adults.
Immediately notify your doctor if you develop any type of rash.
health-medical.infomeds.biz /drug-information/Lamictal.htm   (653 words)

  
 Lamictal
It is also used to control a serious form of epilepsy known as Lennox-Gastaut syndrome.
Lamictal can be added to other epilepsy drugs prescribed for children under 16 who have partial seizures or a serious form of epilepsy known as Lennox-Gastaut syndrome.
Once you've reached a dosage of 500 milligrams per day divided into 2 doses, the doctor will then begin gradually reducing the dosage of the other drug until, after 4 weeks, it has been completely eliminated.
www.healthsquare.com /newrx/lam1217.htm   (977 words)

  
 Re: Lennox Gastaut Syndrome
Re: Lennox Gastaut Syndrome jane 16:49:32 02/04/04 (
Re: Lennox Gastaut Syndrome Angelika Jorgensen 16:56:15 01/20/04 (
Hello, My name is mary and i have a 16 year old son who was diagnosed with Lennox-Gastaut when he was about 12 months old i have never had the opportunity to chat with anyone else who is a parent about this, and I would love to compare notes with you.
www.specialchild.com /bbs3/messages/13154.html   (229 words)

  
 Epinet - Info - Lennox-Gastaut Syndrome
Lennox-Gastaut syndrome (LGS) is one of the more severe forms of epilepsy.
This information may be reproduced for not-for-profit purposes provided its source is appropriately acknowledged.
www.epinet.org.au /epinet2003/info/lennoxGastaut.html   (1679 words)

  
 Topamax Side Effects & Drug Interactions - Topiramate - USA Today
Incidence in Controlled Clinical Trials Ð Add-On Therapy Ð Partial Onset Seizures, Primary Generalized Tonic-Clonic Seizures, and Lennox-Gastaut Syndrome
Table 4 lists treatment-emergent adverse events that occurred in at least 1% of adults treated with 200 to 400 mg/ day topiramate in controlled trials that were numerically more common at this dose than in the patients treated with placebo.
Approximately 11% of the 310 pediatric patients who received topiramate at dosages up to 30 mg/ kg/ day discontin-ued due to adverse events.
www.healthscout.com /rxdetail/68/69/2/main.html   (714 words)

  
 MedlinePlus: Epilepsy
Lennox-Gastaut Syndrome (National Institute of Neurological Disorders and Stroke) - Short Summary
www.nlm.nih.gov /medlineplus/epilepsy.html   (329 words)

  
 Find in a Library: The official parent's sourcebook on Lennox-Gastaut syndrome
Find in a Library: The official parent's sourcebook on Lennox-Gastaut syndrome
WorldCat is provided by OCLC Online Computer Library Center, Inc. on behalf of its member libraries.
worldcatlibraries.org /wcpa/ow/742e21336482008aa19afeb4da09e526.html   (55 words)

  
 clonazepam and pregnancy, canada clonazepam,affect clonazepam side
Klonopin, RX List Monographs:"Epilepsy, absence; Epilepsy, akinetic; Epilepsy, myoclonic; Lennox-Gastaut syndrome; DEA Class CIV; FDA Approved 1975 Jun; Top 200 Drugs; Pregnancy Category D; WHO Formulary; Orphan Drugs."
In humans, clonazepam is capable of suppressing the spike and wave discharge in absence seizures (petit mal) and decreasing the frequency, amplitude, duration and spread of discharge in minor motor seizures."
Clonazepam will cause drowsiness and may cause dizziness.
clonazepam.bayklaver.com /clonazepam-and-pregnancy   (610 words)

  
 ClinicalTrials.gov - Information on Clinical Trials and Human Research Studies: Trial List
Search results for Lennox-Gastaut Syndrome [ALL-FIELDS] are shown below.
clinicaltrials.gov /search/term=Lennox-Gastaut+Syndrome   (64 words)

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