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| | leprosy |
 | | Lepromatous leprosy is a progressive malignant process occurring in persons with decreased cell mediated immunity, and often evolves from indeterminate or borderline leprosy. |
 | | Differential Diagnosis: Among the differential diagnoses for leprosy are (for skin lesions) leishmaniasis, granuloma annulare, granuloma multiforme, lupus erythematosus, lupus vulgaris, psoriasis, pityriasis rosea, yaws, sarcoidosis; and (for peripheral neuropathies) carpal tunnel syndrome, diabetic neuropathy, primary amyloidosis of nerves, and familial hypertrophic neuropathy. |
 | | Patients with borderline or lepromatous leprosy should be treated with a multi-drug regimen such as dapsone 50-100 mg po daily, clofazamine 50 - 200 mg po daily, and rifampin 600 mg/day or 10 mg/kg daily for at least 2-3 years until all biopsies are negative for acid-fast bacilli. |
| www.baylor.edu /~Charles_Kemp/leprosy.htm (1048 words) |
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