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Topic: Lethal dose

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	The Individualist: Lethal Dose (LD50)
		In animal testing studies, and those of other organisms, the dose administered that kills half the test population is referred to as the LD50, for "Lethal Dose, 50%".
		The median infective dose (ID50) is the number of organisms received by a person or test animal qualified by the route of administration (e.g., 1,200 org/man per oral).
		Because of the difficulties in counting actual organisms in a dose, infective doses may be expressed in terms of biological assay, such as the number of LD50's to some test animal.
	www.dadamo.com /wiki/wiki.pl/Lethal_Dose_(LD50) (742 words)

	MySpace.com - LETHAL DOSE - Warsaw, PL - Hardcore / Metal / Rock - www.myspace.com/lethaldosepl
		LETHAL DOSE was set up in may/june of 2003 in Warsaw Poland.
		Some songs was taken from the times before Lethal Dose when Pawel and Maciek played together in other band.
		In December 2006 Lethal Dose finished cooperation with the second guitarist.
	www.myspace.com /lethaldosepl (717 words)

	LD 50 Lethal Dose (2003)
		"Lethal Dose 50" is a stylish British production that deserves a view.
		It's a for sure a great and pleasure full time killer.
		Discuss this title with other users on IMDb message board for LD 50 Lethal Dose (2003)
	www.imdb.com /title/tt0337659 (400 words)

	What is the lethal dose of marijuana? (Site not responding. Last check: )
		In summary, enormous doses of Delta 9 THC, All THC and concentrated marihuana extract ingested by mouth were unable to produce death or organ pathology in large mammals but did produce fatalities in smaller rodents due to profound central nervous system depression.
		These doses would be comparable to a 154-pound human smoking at one time almost three pounds (1.28 kg) of 1%-marihuana or 250,000 times the usual smoked dose and over a million times the minimal effective dose assuming 50% destruction of the THC by smoking.
		This ratio defines the difference between a therapeutically effective dose and a dose which is capable of inducing adverse effects.
	www.druglibrary.org /schaffer/library/mj_overdose.htm (771 words)

	Lethal dose
		Ionizing radiation dose leading to the death of the irradiated individual due to acute radiation injuries.
		The average lethal dose (LD) is the dose where half of the individuals with similar irradiation quantities die.
		is the dose leading to a mortality of 1% of the irradiated persons; consequently, LD is lethal for all (99%) persons irradiated.
	www.euronuclear.org /info/encyclopedia/l/lethal-dose.htm (64 words)

	* Lethal dose - (Environment): Definition (Site not responding. Last check: )
		Lethal dose: (Lethal dose 50/30) The dose of radiation expected to cause death to an exposed population within 30 days to 50 percent (LD 50/30) of those exposed.
		Lethal Dose 50: Also referred to as LD50, the dose of a toxicant that will kill 50 percent of test organisms within a designated period of time; the lower the LD 50, the more toxic the compound.
		Median Lethal Dose (LD50) The amount or concentration of a toxic substance which will result in the death of 50 percent of a group of test organisms upon exposure (by ingestion, application, injection or in their surrounding environment) for a...
	en.mimi.hu /environment/lethal_dose.html (299 words)

	Lethal dose - Biocrawler (Site not responding. Last check: )
		A lethal dose (LD) is an indication of the lethality of a given substance or type of radiation.
		Because resistance varies from one individual to another, the 'lethal dose' represents a dose (usually recorded as dose per kilogram of subject body weight) at which a given percentage of subjects will die.
		The most commonly-used lethality indicator is the LD50, a dose at which 50% of subjects will die.
	www.biocrawler.com /encyclopedia/Lethal_dose (171 words)

	[No title] (Site not responding. Last check: )
		a certain dose kills 50 percent of the subject group (usually rats or mice), that dose is then considered to be the lethal dose.
		The alternative, known as the Fixed Dose Procedure, was developed in Great Britain and is based on toxicologists noticing signs that hint at the lethal dose, instead of having to continue injecting the substances until the animals die.
		The aim is to set a maximum dose level beyond which no further testing is needed because the lethal dose can be predicted.
	www.ynetnews.com /articles/0,7340,L-3060397,00.html (566 words)

	Roger Lewis's calculations
		This level is widely known to represent three times the lethal dose of heroin, but it is not commonly understood that this level is three times the lethal dose even for severe heroin addicts.
		Regardless of the specific dose of heroin, the 1.52mg/L blood morphine level in Cobain allows for the conclusion to be made that he was immediately incapacitated or dead based on the simple fact that no other instance exists on record indicating otherwise, even remotely.
		The lethality of the heroin is so greatly increased that very small doses kill, meaning that "...the interaction of drugs in eliciting acute responses and causing deaths even when sublethal amounts of two or more drugs are present in postmortem specimens from the same cadaver may be a factor." (63).
	pages.intnet.mu /cobain/lewis1.htm (4764 words)

	Brainboost - what is the lethal dose of sarin (Site not responding. Last check: )
		A lethal dose of sarin can kill somebody as quickly as 20 minutes or as slowly as two hours by overloading the human nervous system..
		Nowadays, the lethal dose of sarin on the skin of an averagely built man is estimated to be around 1,800 milligrams.
		The lethal dose of Sarin for an adult is 0.5 milligrams..
	www.brainboost.com /search.asp?Q=what+is+the+lethal+dose+of+sarin&lfmq=1 (350 words)

	The lethal dose (LD) test -(LD-50 test)
		During a lethal dose test, the experimental substance is forced into the animals' throats or is pumped into their stomachs by a tube, sometimes causing death by stomach rupture or from the sheer bulk of the chemical dosage.
		Lethal dose test results can be affected by the age and sex of the animals tested, their housing and nutritional conditions, temperature, time of day and year, and the exact method used to administer the substance.(2) Different species react differently to substances, and reactions between individuals of the same species can also vary greatly.
		For example, nicotine is lethal to humans at 0.9mg/kg, but lethal dose values of nicotine in dogs are a staggering 9.2mg/kg; in pigeons, 75mg/kg; and in rats, 53mg/kg.
	www.geari.org /faqlethaldose.html (612 words)

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	Powerslave.com- Lethal Dose
		Lethal Dose were formed by old friends who shared a passion for loud, aggressive violent music so it was only natural that they came together to create a band in the same vein as the bands they grew up listening to.
		With several more shows under their belt Lethal Dose have launched an all out attack on the heavy metal scene and are preparing to set the club scene ablaze.
		Lethal Dose are sometime in the winter of 2000 Lethal Dose will release their first full length demo.
	www.powerslave.com /bands/bandprofile.php?band_id=136&count=3&page=none (313 words)

	American Scientist Online - The Toxicity of Recreational Drugs (Site not responding. Last check: )
		The median lethal dose for such an adult is approximately 330 grams, the quantity contained in about 20 shots of vodka.
		But coroners are generally hard-pressed to determine the size of the dose because significant redistribution of a drug often occurs after death, typically from tissues of solid organs (such as the liver) into associated blood vessels.
		The largest cluster of substances has a lethal dose that is 10 to 20 times the effective dose: These include cocaine, MDMA (methylenedioxymethamphetamine, often called "ecstasy") and alcohol.
	www.americanscientist.org /template/AssetDetail/assetid/50773?&print=yes (1923 words)

	Lethal dose - ArticleWorld (Site not responding. Last check: )
		The Lethal dose is an indication about the lethality of a substance or type of radiation.
		The Lethal dose depends very much on the subject's resistance, background health, medical history etc. This means that the lethal dose is not the same for all subjects, and this is why it is commonly expressed in quantity of substance/radiation per kilogram of body weight.
		Until a few years ago, the most common way of testing the lethal dose was using animal subjects to which the substance or radiation was gradually administered.
	www.articleworld.org /index.php?title=Lethal_dose&redirect=no (235 words)

	TOXICOLOGY (1223)
		Median lethal concentration (LC50):-The statistically derived exposure concentration of a chemical that can be expected to cause death in 50% of a given population of organisms under a defined set of experimental conditions.
		Median lethal dose (LD50):-The statistically derived single dose of a chemical that can be expected to cause death in 50% of a given population of organisms under a defined set of experimental conditions.
		In fixed dose testing, the test substance is administered to rats or other test species at one dose level: the dose level is selected from preset levels which equate with regulatory classification or ranking systems.
	www.bio.hw.ac.uk /edintox/dose.htm (1556 words)

	EXTOXNET TIBs - DOSE-RESPONSE RELATIONSHIPS IN TOXICOLOGY
		The dose level at which 50 percent of the fish have turned over is known as the ED50, which means effective dose for 50 percent of the fish tested.
		The LD50 (the lethal dose for 50 percent of the animals tested) of a poison is usually expressed in milligrams of chemical per kilogram of body weight (mg/kg).
		The toxic dose does not give any information about the lethal dose because toxic effects (for example, nausea and vomiting) may not be directly related to the way that the chemical causes death.
	extoxnet.orst.edu /tibs/doseresp.htm (1798 words)

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	Estimated Minimum Lethal Dose of Fluoride
		1) The currently accepted estimate for the minimum lethal dose of fluoride is 5 mg/kg (i.e.
		This dose is referred to in the medical literature as the "Probably Toxic Dose" or "PTD." It is sufficient to produce severe poisoning, including death, in some individuals.
		This does not imply that this dose must result in death nor that a somewhat smaller dose would be innocuous.
	www.fluoridealert.org /health/accidents/lethal.html (1432 words)

	Justice For Kurt Cobain - Investigation - Dead Men Don't Pull Triggers - Table 1
		This level is widely known to represent three times the lethal dose of heroin, but it is not commonly understood that this level is three times the lethal dose even for severe heroin addicts.
		Table 2, below, shows that the lethal dose range of intravenous heroin is generally regarded as 10 mg to 12 mg.
		The important thing to note here is that the problems associated with establishing a "lethal dose" for intravenous heroin primarily relates to the problem of establishing a "minimal lethal dose," i.e.
	www.justiceforkurt.com /investigation/dmdpt/table1.shtml (1189 words)

	Erowid LSD Vault : Dosage
		A single drop of potent liquid LSD could be 50 times a normal dose, although it is generally diluted to the point where a single drop is equal to approximately one dose.
		LD50 (That's lethal dose in 50% of those who injest this much) determinations vary widely with species, begin 46 mg/kg in mice, 16.5 mg/kg in rats, 0.3 mg/kg in rabbits and 0.1 mg/kg in elephants.
		Human data are manifestly lacking, and predictions of the average lethal dose for humans have ranged from 0.2 mg/kg to more than 1 mg/kg, administered orally.
	erowid.org /chemicals/lsd/lsd_dose.shtml (1288 words)

	Fluoride Toxicity Issues
		In this paper, on the basis of toxic doses estimated in outbreaks of fluoride poisoning, the potential for acute poisoning by fluoride ingested during mouth rinsing is assessed.
		They state that their studies "suggest" that the minimum lethal dose of fluoride for humans, when consumed over 24 to 32 hours is in the range of 20 mg/kg.
		The generally accepted "certainly lethal dose" range for 70 kg adults, i.e., from 5 to 10 g of sodium fluoride or from 32 to 64 mg fluoride/kg, is discussed.
	www.fluoridation.com /poison.htm (3321 words)

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	Howstuffworks "How Lethal Injection Works"
		For surgical operations, patients are given a dose of 100 to 150 milligrams over a period of 10 to 15 seconds.
		In many states, this drug is given in doses of up to 100 milligrams, a much higher dose than is used in surgical operations -- usually 40 to 100 micrograms per one kilogram of body weight.
		Toxic agent (not used by all states) - Potassium chloride is given at a lethal dose in order to interrupt the electrical signaling essential to heart functions.
	people.howstuffworks.com /lethal-injection4.htm (522 words)

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