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Topic: Lissencephaly

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	Lissencephaly: Encyclopedia of Genetic Disorders
		Lissencephaly, literally meaning smooth brain, is a rare birth abnormality of the brain that results in profound mental retardation and severe seizures.
		Lissencephaly is caused by an arrest in development of the fetal brain during early pregnancy.
		Lissencephaly is one of a number of conditions called "neural migration disorders" that occur because the developing neurons do not proceed correctly to their normal place in the brain's cortex during fetal development.
	health.enotes.com /genetic-disorders-encyclopedia/lissencephaly (2191 words)

	Congenital Brain Defects - Definition, Description, Demographics, Causes and symptoms, Diagnosis, Treatment, Prognosis, ...
		The normal ridges and valleys of the mature brain are formed after cells from the inside of the developing brain migrate to the outside and multiply.
		When these cells fail to migrate, the surface remains smooth, a condition called lissencephaly ("smooth brain").
		Lissencephaly is often associated with facial abnormalities including a small jaw, a high forehead, a short nose, and low-set ears.
	www.healthofchildren.com /C/Congenital-Brain-Defects.html (1974 words)

	Lissencephaly: Physician Information
		While the papers presented here were written to physicians, parents and other lay persons are welcome to use them for additional information on lissencephaly and related syndromes.
		Note: This link will take you to GeneClinics, a clinical information resource relating genetic testing to the diagnosis, management, and genetic counseling of individuals and families with specific inherited disorders.
		Neuronal migration disorders are a group of malformations of the brain which primarily affect development of the cerebral cortex.
	www.lissencephaly.org /medical/info/index.htm (314 words)

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