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| | eMedicine - Local Anesthetics : Article by Don R Revis, Jr, MD (Site not responding. Last check: 2007-10-08) |
 | | Local anesthetics differ in respect to the pH at which the ionized and nonionized forms are present at equilibrium, but this pH is generally in the range of 7.6-8.9. |
 | | For proper administration of local anesthetics, consider the individual characteristics of the patient, dose of local anesthetic to be administered, presence or absence of epinephrine, speed of administration, local tissue vascularity, and technique of administration. |
 | | Local anesthetics decrease the rate of depolarization of cardiac tissue, which is the rationale behind the use of lidocaine in treatment of ventricular arrhythmias. |
| www.emedicine.com /ent/topic20.htm (3188 words) |
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